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1. ((1s,2s,4r)-4-(4-((1s)-2,3-dihydro-1h-inden-1-ylamino)-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Sulfamate
2. ((1s,2s,4r)-4-(4-((1s)-2,3-dihydro-1h-inden-1-ylamino)-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Sulphamate
3. 4-(4-((1s)-2,3-dihydro-1h-inden-1-ylamino)-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl Methyl Sulfamidate
4. Mln-4924
5. Mln4924
1. Mln4924
2. Mln-4924
3. 905579-51-3
4. Mln 4924
5. Pevonedistat (mln-4924)
6. ((1s,2s,4r)-4-(4-(((s)-2,3-dihydro-1h-inden-1-yl)amino)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Sulfamate
7. Mln-4924003
8. S3azd8d215
9. 905579-51-3 (free Base)
10. Pevonedistat (usan)
11. Pevonedistat [usan]
12. [(1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl Sulfamate
13. Sulfamic Acid [(1s,2s,4r)-4-[4-[[(1s)-2,3-dihydro-1h-inden-1-yl]amino]-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl Ester
14. ((1s,2s,4r)-4-(4-((1s)-2,3-dihydro-1h-inden-1-ylamino)-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Sulfamate
15. Sulfamic Acid, ((1s,2s,4r)-4-(4-(((1s)-2,3-dihydro-1h-inden-1-yl)amino)-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Ester
16. Pevonedistat [usan:inn]
17. Pevonedistatum
18. Unii-s3azd8d215
19. 3gzn
20. ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl Sulfamate
21. B39
22. Pevonedistat; Mln4924
23. Pevonedistat [inn]
24. ((1s,2s,4r)-4-(4-((1s)-2,3-dihydro-1h-inden-1-ylamino)-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Sulphamate
25. Mls006010830
26. Pevonedistat [who-dd]
27. Schembl192875
28. Tak924
29. Chembl1231160
30. Chebi:95028
31. Gtpl12117
32. Tak-924
33. Chebi:145535
34. Dtxsid701022549
35. Ex-a1472
36. Bdbm50285607
37. Nsc793435
38. Zinc58660702
39. Akos025401927
40. Cs-0348
41. Db11759
42. Nsc-793435
43. Ncgc00345794-02
44. Ncgc00345794-07
45. Ncgc00345794-10
46. [(1s,2s,4r)-4-[4-[[(1s)-2,3-dihydro-1h-inden-1-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl Sulfamate
47. [(1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl Sulfamate
48. 4-(4-((1s)-2,3-dihydro-1h-inden-1-ylamino)-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl Methyl Sulfamidate
49. Ac-27394
50. Hy-70062
51. Smr004701757
52. D10413
53. Brd-k67844266-001-01-3
54. Q27166792
55. ((1s,2s,4r)-4-(4-(((1s)-2,3-dihydro-1h-inden-1-yl)amino(-7h-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Sulfamate
56. ((1s,2s,4r)-4-(4-((s)-2,3-dihydro-1h-inden-1-ylamino)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl Sulfamate
57. ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo[2,3-d]-pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl Sulfamate
58. [(1s,2s,4r)-4-[4-[[(1s)-2,3-dihydro-1h-inden-1-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxy-cyclopentyl]methyl Sulfamate
| Molecular Weight | 443.5 g/mol |
|---|---|
| Molecular Formula | C21H25N5O4S |
| XLogP3 | 1.7 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 6 |
| Exact Mass | 443.16272547 g/mol |
| Monoisotopic Mass | 443.16272547 g/mol |
| Topological Polar Surface Area | 141 Ų |
| Heavy Atom Count | 31 |
| Formal Charge | 0 |
| Complexity | 734 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Treatment of acute myeloid leukaemia, Treatment of myelodysplastic syndromes
Enzyme Inhibitors
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)
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PharmaCompass offers a list of Pevonedistat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Pevonedistat manufacturer or Pevonedistat supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Pevonedistat manufacturer or Pevonedistat supplier.
PharmaCompass also assists you with knowing the Pevonedistat API Price utilized in the formulation of products. Pevonedistat API Price is not always fixed or binding as the Pevonedistat Price is obtained through a variety of data sources. The Pevonedistat Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Pevonedistat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pevonedistat, including repackagers and relabelers. The FDA regulates Pevonedistat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pevonedistat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Pevonedistat supplier is an individual or a company that provides Pevonedistat active pharmaceutical ingredient (API) or Pevonedistat finished formulations upon request. The Pevonedistat suppliers may include Pevonedistat API manufacturers, exporters, distributors and traders.
Pevonedistat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Pevonedistat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pevonedistat GMP manufacturer or Pevonedistat GMP API supplier for your needs.
A Pevonedistat CoA (Certificate of Analysis) is a formal document that attests to Pevonedistat's compliance with Pevonedistat specifications and serves as a tool for batch-level quality control.
Pevonedistat CoA mostly includes findings from lab analyses of a specific batch. For each Pevonedistat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Pevonedistat may be tested according to a variety of international standards, such as European Pharmacopoeia (Pevonedistat EP), Pevonedistat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pevonedistat USP).
