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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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MARKET PLACE

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API

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FDF

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Listed Dossiers

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Data Compilation #PharmaFlow

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Chemistry

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Also known as: 51753-57-2, Fenazepam, Phenazapam, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one, Bd 98, C15h10brcln2o
Molecular Formula
C15H10BrClN2O
Molecular Weight
349.61  g/mol
InChI Key
CGMJQQJSWIRRRL-UHFFFAOYSA-N
FDA UNII
3DSB43090Z

Phenazepam
1 2D Structure

Phenazepam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-bromo-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
2.1.2 InChI
InChI=1S/C15H10BrClN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
2.1.3 InChI Key
CGMJQQJSWIRRRL-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1C(=O)NC2=C(C=C(C=C2)Br)C(=N1)C3=CC=CC=C3Cl
2.2 Other Identifiers
2.2.1 UNII
3DSB43090Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7-bromo-5-(2-chlorophenyl) 1,3-dihydro-2h-1,4-benzodiazepin-2-one

2. 7-bromo-5-(2-chlorphenyl)-1,2-dihydro-3h-1,4-benzodiazepin-2-one

3. Fenazepam

4. Phenazepam, 2-(14)c-labeled Cpd

2.3.2 Depositor-Supplied Synonyms

1. 51753-57-2

2. Fenazepam

3. Phenazapam

4. 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one

5. Bd 98

6. C15h10brcln2o

7. 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one

8. 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-3h-1,4-benzodiazepin-2-one

9. 3dsb43090z

10. 2h-1,4-benzodiazepin-2-one, 1,3-dihydro-7-bromo-5-(2-chlorophenyl)-

11. 2h-1,4-benzodiazepin-2-one, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-

12. Brn 0889456

13. Unii-3dsb43090z

14. Phenzitat

15. Phenazepam-d4 Solution

16. Chemdivam_001103

17. 7-bromo-5-(2-chlorophenyl)-2,3-dihydro-1h-1,4-benzodiazepin-2-one

18. Chemdiv1_028228

19. Phenazepam, Beta-polymorph

20. Phenazepam [mart.]

21. Mixcom6_000420

22. N05ba

23. Phenazepam [who-dd]

24. Oprea1_009938

25. Oprea1_527397

26. 5-24-04-00341 (beilstein Handbook Reference)

27. Mls001143339

28. Schembl416137

29. Zinc1919

30. Chembl1709464

31. Hms667d02

32. Dtxsid00199685

33. 5-(2-chlorophenyl)-7-bromo-1,4-benzodiazepin-2-one

34. Bd-98

35. Hms2780h09

36. Phenazepam 0.1 Mg/ml In Methanol

37. Phenazepam 1.0 Mg/ml In Methanol

38. Bcp22944

39. Stk183542

40. Akos000668996

41. Ncgc00390271-01

42. Smr000473174

43. Bcp0726000150

44. 753p572

45. Q421138

46. 7-bromo-5-(2-chlorophenyl)-1h-1,4-benzodiazepin-2(3h)-one

47. 7-bromo-5-(2-chlorophenyl)-1h-benzo[e][1,4]diazepin-2(3h)-one

48. 7-bromo-5-(2'-chloro-phenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one

49. 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one #

50. 7-bromo-5-(2-chlorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one 2h-1,4-benzodiazepin-2-one

51. Phenazepam Solution, 1.0 Mg/ml In Acetonitrile, Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date
2005-03-28
3 Chemical and Physical Properties
Molecular Weight 349.61 g/mol
Molecular Formula C15H10BrClN2O
XLogP33.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass347.96650 g/mol
Monoisotopic Mass347.96650 g/mol
Topological Polar Surface Area41.5 Ų
Heavy Atom Count20
Formal Charge0
Complexity415
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adjuvants, Immunologic

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)


Anticonvulsants

Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)


GABA Agents

Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as GABA Agents.)


Anti-Arrhythmia Agents

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)


API SUPPLIERS

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01

Olpha

Latvia

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothOlpha, a JSC AB City subsidiary, is a leading Baltic firm with 50 years of experience in medicines & chemical pharmaceuticals.

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Olpha

02

R L Fine Chem

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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R L Fine Chem

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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03

Centaur Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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Listed Suppliers

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01

Olpha

Latvia
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Pharma, Lab & Chemical Expo
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothOlpha, a JSC AB City subsidiary, is a leading Baltic firm with 50 years of experience in medicines & chemical pharmaceuticals.

Flag Latvia
Digital Content Digital Content

Phenazepam

About the Company : Olpha, the subsidiary of JSC AB City, is one of the largest companies in the Baltic states with 50 years of experience in the production of medicines & chemical pharmaceutical prod...

Olpha, the subsidiary of JSC AB City, is one of the largest companies in the Baltic states with 50 years of experience in the production of medicines & chemical pharmaceutical products. The range of product portfolio developed by the company, includes 60 formulations, 25 APIs & >20 intermediates, including medicinal products for the nervous system, cardiovascular health, as well as antiviral, antibacterial & anti-allergic drugs. The health care products created by Olpha ensure both, the even more broader access of users to the necessary medicinal products, as well as the company’s growth & reputation in the global market.
Olpha

02

Pharma, Lab & Chemical Expo
Not Confirmed
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Phenazepam

About the Company : Centaur accepts change as a constant, and continuously innovates to remain significant. Centaur has built knowledge sharing relationships with the pharmaceutical majors in areas of...

Centaur accepts change as a constant, and continuously innovates to remain significant. Centaur has built knowledge sharing relationships with the pharmaceutical majors in areas of product development, custom synthesis, contract research and contract manufacturing. Centaur formulations and API are exported across 5 continents and more than 60 countries including regulated markets. Formulations Centaur ranks among India's TOP 50 pharmaceutical companies by prescriptions (CMarc) and by stockist audit (ORG-IMS). Centaur's All-India network includes a 1000 strong sales force that covers 250,000 doctors and 250,000 retailers every month.
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03

Pharma, Lab & Chemical Expo
Not Confirmed
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Phenazepam

About the Company : Established in 1984, R L Fine Chem Pvt. Ltd. is one of the fastest growing API companies, with a leadership position in several APIs such as antihistamines, antidepressants and mus...

Established in 1984, R L Fine Chem Pvt. Ltd. is one of the fastest growing API companies, with a leadership position in several APIs such as antihistamines, antidepressants and muscle relaxants. Acquired by private equity groups in 2016, it is one of India’s leading manufacturers of psychotropic substances. It supplies over 60 APIs to customers in more than 62 countries from FDA and EU-approved locations. R L Fine Chem is a technology-driven company with a focus on the in-house manufacture of key intermediates for our APIs. The company currently operates out of four facilities in the Indian states of Karnataka and Andhra Pradesh.
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ABOUT THIS PAGE

Phenazepam Manufacturers

A Phenazepam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Phenazepam, including repackagers and relabelers. The FDA regulates Phenazepam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Phenazepam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Phenazepam manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Phenazepam Suppliers

A Phenazepam supplier is an individual or a company that provides Phenazepam active pharmaceutical ingredient (API) or Phenazepam finished formulations upon request. The Phenazepam suppliers may include Phenazepam API manufacturers, exporters, distributors and traders.

click here to find a list of Phenazepam suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Phenazepam GMP

Phenazepam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Phenazepam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Phenazepam GMP manufacturer or Phenazepam GMP API supplier for your needs.

Phenazepam CoA

A Phenazepam CoA (Certificate of Analysis) is a formal document that attests to Phenazepam's compliance with Phenazepam specifications and serves as a tool for batch-level quality control.

Phenazepam CoA mostly includes findings from lab analyses of a specific batch. For each Phenazepam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Phenazepam may be tested according to a variety of international standards, such as European Pharmacopoeia (Phenazepam EP), Phenazepam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Phenazepam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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