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Chemistry

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Also known as: Phenolsulfonphthalein, 143-74-8, Fenolipuna, Sulfonphthal, Sulphental, Sulphonthal
Molecular Formula
C19H14O5S
Molecular Weight
354.4  g/mol
InChI Key
BELBBZDIHDAJOR-UHFFFAOYSA-N
FDA UNII
I6G9Y0J1OJ

Phenol Red
Red dye, pH indicator, and diagnostic aid for determination of renal function. It is used also for studies of the gastrointestinal and other systems.
1 2D Structure

Phenol Red

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,16-benzoxathiol-3-yl]phenol
2.1.2 InChI
InChI=1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
2.1.3 InChI Key
BELBBZDIHDAJOR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC=C2C(=C1)C(OS2(=O)=O)(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O
2.2 Other Identifiers
2.2.1 UNII
I6G9Y0J1OJ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Phenolsulfonphthalein

2. Sulfonphthal

3. Sulphental

4. Sulphonthal

2.3.2 Depositor-Supplied Synonyms

1. Phenolsulfonphthalein

2. 143-74-8

3. Fenolipuna

4. Sulfonphthal

5. Sulphental

6. Sulphonthal

7. Phenolsulphonphthalein

8. Psp (indicator)

9. Phenolsulfonephthalein

10. Phenolred

11. Phenol, 4,4'-(1,1-dioxido-3h-2,1-benzoxathiol-3-ylidene)bis-

12. 3,3-bis(4-hydroxyphenyl)-3h-benzo[c][1,2]oxathiole 1,1-dioxide

13. Nsc10459

14. Phenosulfophthalein

15. Mfcd00003552

16. Nsc 10459

17. Nsc-10459

18. Psp

19. I6g9y0j1oj

20. 4,4'-(3h-2,1-benzoxathiol-3-ylidene)diphenol S,s-dioxide

21. 4,4'-(1,1-dioxido-3h-2,1-benzoxathiole-3,3-diyl)diphenol

22. Chebi:31991

23. 3h-2,1-benzoxathiole, 3,3-bis(4-hydroxyphenyl)-, 1,1-dioxide

24. Phenol, 4,4-(3h-2,1-benzoxathiol-3-ylidene)di-, S-s-dioxide

25. 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol

26. P. S. P.

27. Ncgc00013109-03

28. Phenol, 4,4'-(3h-2,1-benzoxathiol-3-ylidene)di-, S,s-dioxide

29. Dsstox_cid_2408

30. Phenol, 4,4'-(3h-2,1-benzoxathiol-3-ylidene)bis-, (s,s-dioxide)

31. Dsstox_rid_76578

32. Dsstox_gsid_22408

33. Phenol-red

34. Phenolsulfonephthalein Sodium Salt

35. Cas-143-74-8

36. Einecs 205-609-7

37. Unii-i6g9y0j1oj

38. Brn 0326470

39. Phenolsulfonphthalein [jan:nf]

40. Phenol Red, Psp

41. Phenol Red Solution

42. Phenol Red Indicator

43. Phenol Red Acs Grade

44. Phenol Red, Free Acid

45. Phenol, 4,4'-(3h-2,1-benzoxathiol-3-ylidene)bis-, S,s-dioxide

46. Phenol Red, Acs Reagent

47. Phenol Red, Recrystallized

48. Phenolsulfonphthalein (tn)

49. Ncistruc1_001090

50. Ncistruc2_000839

51. Schembl17836

52. 5-19-03-00457 (beilstein Handbook Reference)

53. Bidd:er0046

54. Chembl258921

55. Phenol Red, Jis Special Grade

56. Dtxsid8022408

57. Phenol Red, P.a., Acs Reagent

58. Phenolsulfonphthalein (jp17/nf)

59. Phenolsulfonphthalein [mi]

60. 3,3-bis(4-hydroxyphenyl)benzo[c]1,2-oxathiolene-1,1-dione

61. 3,3-bis(p-hydroxyphenyl)-3h-2,1-benzoxathiole 1,1-dioxide

62. Phenolsulfonphthalein [jan]

63. Amy22406

64. Hy-d0169

65. Nci10459

66. Phenolsulfonphthalein [inci]

67. Zinc3860918

68. Phenolsulfonphthalein [vandf]

69. Tox21_110012

70. Tox21_303570

71. Bbl000596

72. Ccg-36909

73. Ncgc00013109

74. Phenol Red Solution, Ph 6.8-8.4

75. Phenolsulfonphthalein [mart.]

76. Stk364540

77. Phenolsulfonphthalein [who-dd]

78. 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]phenol

79. Akos000592531

80. Tox21_110012_1

81. Db13212

82. Ncgc00013109-01

83. Ncgc00013109-02

84. Ncgc00096230-01

85. Ncgc00257424-01

86. Ac-18338

87. Nci60_000111

88. Vs-00652

89. Db-042702

90. Phenolsulfonphthalein [ep Monograph]

91. Cs-0010076

92. Ft-0631835

93. P0100

94. P0101

95. P0703

96. D01200

97. D70382

98. P-2800

99. P-2801

100. Phenol Red Solution 0.5%, Cell Culture Tested

101. Ab00444024_03

102. A884896

103. Q418719

104. Sr-01000357546

105. 3h-2, 3,3-bis(4-hydroxyphenyl)-, 1,1-dioxide

106. Sr-01000357546-1

107. Brd-k79892937-001-01-7

108. Phenol Red, Powder, Bioreagent, Suitable For Cell Culture

109. 3,3-bis(4-hydroxyphenyl)-3h-2,1??-benzoxathiole-1,1-dione

110. 4,4'-(3h,2,1-benzoxathiol-3-ylidene)bisphenol S,s-dioxide

111. 4,4'-(3h-2,1-benzoxathiol-3-yildene)bisphenol S,s-dioxide

112. 4,4'-(3h-2,1-benzoxathiol-3-ylidene)bisphenol S,s-dioxide

113. Phenol,4'-(3h-2,1-benzoxathiol-3-ylidene)bis-, S,s-dioxide

114. Phenol,4'-(3h-2,1-benzoxathiol-3-ylidene)di-, S,s-dioxide

115. Phenol,4-(3h-2,1-benzoxathiol-3-ylidene)di-, S,s-dioxide

116. Phenol,4-(3h-2,1-benzoxathiol-3-ylidene)di-, S-s-dioxide

117. 3,3-bis(4-hydroxyphenyl)-3h-2,1-benzoxathiole 1,1-dioxide

118. 4,4'-(1,1-dioxido-3h-2,1-benzoxathiol-3-ylidene)bis-phenol Sodium Salt

119. Phenol, 4,4'-(3h-2,1-benzoxathiol-3-ylidene)bis-,s,s-dioxide (9ci)

120. Alpha-hydroxy-alpha,alpha-bis(p-hydroxyphenyl)-o-toluenesulfonic Acid Gamma-sultone

121. Phenol Red Solution, 0.5%, Liquid, Sterile-filtered, Bioreagent, Suitable For Cell Culture

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 354.4 g/mol
Molecular Formula C19H14O5S
XLogP33
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass354.05619472 g/mol
Monoisotopic Mass354.05619472 g/mol
Topological Polar Surface Area92.2 Ų
Heavy Atom Count25
Formal Charge0
Complexity545
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Indicators and Reagents

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)


Coloring Agents

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)


4.2 ATC Code

V - Various

V04 - Diagnostic agents

V04C - Other diagnostic agents

V04CH - Tests for renal function and ureteral injuries

V04CH03 - Phenolsulfonphthalein


API Reference Price

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14-Jan-2021
21-Nov-2024
KGS
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Quantity (KGS) & Unit rate (USD/KGS) over time

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Phenol Red Manufacturers

A Phenol Red manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Phenol Red, including repackagers and relabelers. The FDA regulates Phenol Red manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Phenol Red API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Phenol Red manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Phenol Red Suppliers

A Phenol Red supplier is an individual or a company that provides Phenol Red active pharmaceutical ingredient (API) or Phenol Red finished formulations upon request. The Phenol Red suppliers may include Phenol Red API manufacturers, exporters, distributors and traders.

click here to find a list of Phenol Red suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Phenol Red JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Phenol Red Drug Master File in Japan (Phenol Red JDMF) empowers Phenol Red API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Phenol Red JDMF during the approval evaluation for pharmaceutical products. At the time of Phenol Red JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Phenol Red suppliers with JDMF on PharmaCompass.

Phenol Red GMP

Phenol Red Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Phenol Red GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Phenol Red GMP manufacturer or Phenol Red GMP API supplier for your needs.

Phenol Red CoA

A Phenol Red CoA (Certificate of Analysis) is a formal document that attests to Phenol Red's compliance with Phenol Red specifications and serves as a tool for batch-level quality control.

Phenol Red CoA mostly includes findings from lab analyses of a specific batch. For each Phenol Red CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Phenol Red may be tested according to a variety of international standards, such as European Pharmacopoeia (Phenol Red EP), Phenol Red JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Phenol Red USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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