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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

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JDMF

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EU WC

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FDF

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Listed Dossiers

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DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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USP

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4 RELATED EXCIPIENT COMPANIES

7EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Phloridzin, 60-81-1, Phlorhizin, Phlorizoside, Floridzin, Phlorrhizin
Molecular Formula
C21H24O10
Molecular Weight
436.4  g/mol
InChI Key
IOUVKUPGCMBWBT-QNDFHXLGSA-N
FDA UNII
CU9S17279X

Phlorhizin
phlorizin is a natural product found in Malus doumeri, Vaccinium macrocarpon, and other organisms with data available.
1 2D Structure

Phlorhizin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
2.1.2 InChI
InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1
2.1.3 InChI Key
IOUVKUPGCMBWBT-QNDFHXLGSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O
2.1.5 Isomeric SMILES
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
CU9S17279X
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Phlorhizin

2. Phloridzin

2.3.2 Depositor-Supplied Synonyms

1. Phloridzin

2. 60-81-1

3. Phlorhizin

4. Phlorizoside

5. Floridzin

6. Phlorrhizin

7. Phloretin 2'-glucoside

8. Phloridzosid

9. Phlorrhizen

10. Phlorizine

11. Phloridzinum

12. Nsc 2833

13. Phloretin-2'-o-beta-glucoside

14. Ai3-19835

15. Phloridzin Dihydrate

16. Phloretin-2'-beta-glucoside

17. Chebi:8113

18. Chembl245067

19. 7061-54-3

20. Phloretin-2'-o-.beta.-glucoside

21. Cu9s17279x

22. Nsc-2833

23. 2'-(beta-d-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone

24. 1-[2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone

25. 1-propanone, 1-(2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)-

26. 1-(2,4-dihydroxy-6-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one

27. 1-(2,4-dihydroxy-6-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one

28. Phloretin 2'-o-glucoside

29. 1-propanone, 1-[2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-

30. 2'-(.beta.-d-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone

31. Sr-01000781913

32. Einecs 200-487-1

33. Lopin

34. Unii-cu9s17279x

35. 1-propanone, 1-[2-(.beta.-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-

36. O-glucoside, 1

37. 1-propanone, 1-(2-(.beta.-d-glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)-

38. Phlorizin (phloridzin)

39. Spectrum_001291

40. Phloridzin [mi]

41. Specplus_000325

42. Spectrum2_000701

43. Spectrum3_001227

44. Spectrum4_001651

45. Spectrum5_000521

46. Phloridzin [inci]

47. Phloretin-2'-o-glucoside

48. Phloridzinum [hpus]

49. Phloridzin [who-dd]

50. Schembl17290

51. Bspbio_002674

52. Kbiogr_002141

53. Kbioss_001771

54. Spectrum300547

55. Jmc511145 Compound 1

56. Divk1c_006421

57. Spbio_000881

58. Gtpl4757

59. Dtxsid3075339

60. Bdbm20875

61. Kbio1_001365

62. Kbio2_001771

63. Kbio2_004339

64. Kbio2_006907

65. Kbio3_002174

66. Hms2090p10

67. Phloretin 2'-ss-d-glucopyranoside

68. Act03316

69. Hy-n0143

70. Zinc3875408

71. Ccg-38341

72. S2343

73. 3,5-dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl Beta-d-glucopyranoside

74. 4,6-dihydroxy-2-(beta-d-glucosido)-beta-(p-hydroxyphenyl)propiophenone

75. Akos015920054

76. Ac-7976

77. Cs-2013

78. Sdccgmls-0066626.p001

79. 1-propanone,1-[2-(b-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-

80. Ncgc00142423-01

81. Ncgc00142423-02

82. Ncgc00142423-06

83. 1-[2,4-dihydroxy-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one

84. 1-[2,4-dihydroxy-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-phenyl]-3-(4-hydroxyphenyl)propan-1-one

85. 1-{6-[(2s,4s,5s,3r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)(2h-3,4,5,6-tetrahydr Opyran-2-yloxy)]-2,4-dihydroxyphenyl}-3-(4-hydroxyphenyl)propan-1-one

86. As-15724

87. N1876

88. P0248

89. C01604

90. 006p591

91. A836937

92. A868885

93. Q413105

94. Q-100699

95. Sr-01000781913-2

96. Sr-01000781913-4

97. Sr-01000781913-5

98. Brd-k73756878-001-02-9

99. 1-[2-(.beta.-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone

100. 1-[2-(?-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone

101. 1-[2-(ss-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone

102. 1-(2,4-dihydroxy-6-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yloxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one

103. 1-[2,4-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-phenyl]-3-(4-hydroxyphenyl)propan-1-one Dihydrate;phlorizin Dihydrate

104. 112318-65-7

2.4 Create Date
2005-06-08
3 Chemical and Physical Properties
Molecular Weight 436.4 g/mol
Molecular Formula C21H24O10
XLogP31.2
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass436.13694696 g/mol
Monoisotopic Mass436.13694696 g/mol
Topological Polar Surface Area177 Ų
Heavy Atom Count31
Formal Charge0
Complexity581
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Phlorhizin Manufacturers

A Phlorhizin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Phlorhizin, including repackagers and relabelers. The FDA regulates Phlorhizin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Phlorhizin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Phlorhizin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Phlorhizin Suppliers

A Phlorhizin supplier is an individual or a company that provides Phlorhizin active pharmaceutical ingredient (API) or Phlorhizin finished formulations upon request. The Phlorhizin suppliers may include Phlorhizin API manufacturers, exporters, distributors and traders.

click here to find a list of Phlorhizin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Phlorhizin USDMF

A Phlorhizin DMF (Drug Master File) is a document detailing the whole manufacturing process of Phlorhizin active pharmaceutical ingredient (API) in detail. Different forms of Phlorhizin DMFs exist exist since differing nations have different regulations, such as Phlorhizin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Phlorhizin DMF submitted to regulatory agencies in the US is known as a USDMF. Phlorhizin USDMF includes data on Phlorhizin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Phlorhizin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Phlorhizin suppliers with USDMF on PharmaCompass.

Phlorhizin GMP

Phlorhizin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Phlorhizin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Phlorhizin GMP manufacturer or Phlorhizin GMP API supplier for your needs.

Phlorhizin CoA

A Phlorhizin CoA (Certificate of Analysis) is a formal document that attests to Phlorhizin's compliance with Phlorhizin specifications and serves as a tool for batch-level quality control.

Phlorhizin CoA mostly includes findings from lab analyses of a specific batch. For each Phlorhizin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Phlorhizin may be tested according to a variety of international standards, such as European Pharmacopoeia (Phlorhizin EP), Phlorhizin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Phlorhizin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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