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Also known as: 108-73-6, Benzene-1,3,5-triol, 1,3,5-trihydroxybenzene, 1,3,5-benzenetriol, Phloroglucin, Phloroglucine
Molecular Formula
C6H6O3
Molecular Weight
126.11  g/mol
InChI Key
QCDYQQDYXPDABM-UHFFFAOYSA-N
FDA UNII
DHD7FFG6YS

Phloroglucinol
A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
1 2D Structure

Phloroglucinol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
benzene-1,3,5-triol
2.1.2 InChI
InChI=1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H
2.1.3 InChI Key
QCDYQQDYXPDABM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=C(C=C(C=C1O)O)O
2.2 Other Identifiers
2.2.1 UNII
DHD7FFG6YS
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,3,5-benzenetriol

2. Benzene-1,3,5-triol

3. Spasfon-lyoc

4. Spassirex

2.3.2 Depositor-Supplied Synonyms

1. 108-73-6

2. Benzene-1,3,5-triol

3. 1,3,5-trihydroxybenzene

4. 1,3,5-benzenetriol

5. Phloroglucin

6. Phloroglucine

7. Spasfon-lyoc

8. Dilospan S

9. Sym-trihydroxybenzene

10. S-trihydroxybenzene

11. 5-hydroxyresorcinol

12. Benzene-s-triol

13. 3,5-dihydroxyphenol

14. Benzene, Trihydroxy

15. 5-oxyresorcinol

16. Phloroglucinol Anhydrous

17. Floroglucinol

18. Floroglucin

19. 5-oxyresorcinolphloroglucin

20. 1,3,5-thb

21. 1,3,5-trihydroxycyclohexatriene

22. 1,3,5-triol

23. Benzene, 1,3,5-trihydroxy-

24. 5-benzenetriol

25. 1,2,5-trihydroxybenzene

26. Nsc 1572

27. Mfcd00002286

28. Phloroglucinol (jan)

29. Dhd7ffg6ys

30. Nsc-1572

31. Benezene-1,3,5-triol

32. Chembl473159

33. Chebi:16204

34. Phloroglucinol [jan]

35. Floroglucin [czech]

36. Floroglucinol [czech]

37. Phloroglucinol, Anhydrous

38. Ccris 4147

39. Unii-dhd7ffg6ys

40. Ncgc00166270-01

41. Einecs 203-611-2

42. Brn 1341907

43. Ai3-08848

44. Phloroglucinol Ts

45. 1,5-benzenetriol

46. 13x

47. Dilospan S (tn)

48. Phloroglucinol [ban]

49. 1,5-trihydroxybenzene

50. 1,5-triol

51. Benzene,3,5-trihydroxy-

52. Wln: Qr Cq Eq

53. 1,3,5-trihydroxylbenzene

54. 1,3,5-trihydroxy Benzene

55. 1,3,5-trihydroxy-benzene

56. Phloroglucinol [mi]

57. 1,3, 5-trihydroxybenzene

58. Schembl26311

59. Phloroglucinol [inci]

60. 1,5-trihydroxycyclohexatriene

61. 4-06-00-07361 (beilstein Handbook Reference)

62. Phloroglucinol, P.a., 99%

63. Phloroglucinol [mart.]

64. Phloroglucinol [who-dd]

65. 1,3,5-benzenetriol, Anhydrous

66. Dtxsid9048354

67. Nsc1572

68. Zinc391883

69. Act13446

70. Bbl018701

71. Bdbm50249069

72. Phloroglucinol [ep Monograph]

73. Stl146346

74. Phloroglucinol (1,3,5-benzenetriol)

75. Phloroglucinol, >=99.0% (hplc)

76. Akos000119851

77. Am84333

78. Db12944

79. Fs-4574

80. 1,3,5-benzenetriol (acd/name 4.0)

81. Ncgc00166270-02

82. Ac-10081

83. Ft-0606511

84. Ft-0673853

85. P0249

86. P1376

87. Phloroglucinol 100 Microg/ml In Acetonitrile

88. C02183

89. D00152

90. F13526

91. A801919

92. Q899008

93. Q-200070

94. Phloroglucinol, Plant Cell Culture Tested, Bioreagent

95. F0001-0177

96. Phloroglucinol, Used To Detect The Presence Of Wood Fiber.

97. Phloroglucinol (anhydrous), European Pharmacopoeia (ep) Reference Standard

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 126.11 g/mol
Molecular Formula C6H6O3
XLogP30.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass126.031694049 g/mol
Monoisotopic Mass126.031694049 g/mol
Topological Polar Surface Area60.7 Ų
Heavy Atom Count9
Formal Charge0
Complexity63.3
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Indicators and Reagents

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)


4.2 ATC Code

A - Alimentary tract and metabolism

A03 - Drugs for functional gastrointestinal disorders

A03A - Drugs for functional gastrointestinal disorders

A03AX - Other drugs for functional gastrointestinal disorders

A03AX12 - Phloroglucinol


4.3 Metabolism/Metabolites

Phloroglucinol is a known human metabolite of 2-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one and Epicatechin.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


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Looking for 108-73-6 / Phloroglucinol API manufacturers, exporters & distributors?

Phloroglucinol manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Phloroglucinol API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Phloroglucinol manufacturer or Phloroglucinol supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Phloroglucinol manufacturer or Phloroglucinol supplier.

PharmaCompass also assists you with knowing the Phloroglucinol API Price utilized in the formulation of products. Phloroglucinol API Price is not always fixed or binding as the Phloroglucinol Price is obtained through a variety of data sources. The Phloroglucinol Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Phloroglucinol

Synonyms

108-73-6, Benzene-1,3,5-triol, 1,3,5-trihydroxybenzene, 1,3,5-benzenetriol, Phloroglucin, Phloroglucine

Cas Number

108-73-6

Unique Ingredient Identifier (UNII)

DHD7FFG6YS

About Phloroglucinol

A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.

Phloroglucinol Manufacturers

A Phloroglucinol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Phloroglucinol, including repackagers and relabelers. The FDA regulates Phloroglucinol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Phloroglucinol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Phloroglucinol manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Phloroglucinol Suppliers

A Phloroglucinol supplier is an individual or a company that provides Phloroglucinol active pharmaceutical ingredient (API) or Phloroglucinol finished formulations upon request. The Phloroglucinol suppliers may include Phloroglucinol API manufacturers, exporters, distributors and traders.

click here to find a list of Phloroglucinol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Phloroglucinol USDMF

A Phloroglucinol DMF (Drug Master File) is a document detailing the whole manufacturing process of Phloroglucinol active pharmaceutical ingredient (API) in detail. Different forms of Phloroglucinol DMFs exist exist since differing nations have different regulations, such as Phloroglucinol USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Phloroglucinol DMF submitted to regulatory agencies in the US is known as a USDMF. Phloroglucinol USDMF includes data on Phloroglucinol's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Phloroglucinol USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Phloroglucinol suppliers with USDMF on PharmaCompass.

Phloroglucinol KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Phloroglucinol Drug Master File in Korea (Phloroglucinol KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Phloroglucinol. The MFDS reviews the Phloroglucinol KDMF as part of the drug registration process and uses the information provided in the Phloroglucinol KDMF to evaluate the safety and efficacy of the drug.

After submitting a Phloroglucinol KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Phloroglucinol API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Phloroglucinol suppliers with KDMF on PharmaCompass.

Phloroglucinol CEP

A Phloroglucinol CEP of the European Pharmacopoeia monograph is often referred to as a Phloroglucinol Certificate of Suitability (COS). The purpose of a Phloroglucinol CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Phloroglucinol EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Phloroglucinol to their clients by showing that a Phloroglucinol CEP has been issued for it. The manufacturer submits a Phloroglucinol CEP (COS) as part of the market authorization procedure, and it takes on the role of a Phloroglucinol CEP holder for the record. Additionally, the data presented in the Phloroglucinol CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Phloroglucinol DMF.

A Phloroglucinol CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Phloroglucinol CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Phloroglucinol suppliers with CEP (COS) on PharmaCompass.

Phloroglucinol GMP

Phloroglucinol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Phloroglucinol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Phloroglucinol GMP manufacturer or Phloroglucinol GMP API supplier for your needs.

Phloroglucinol CoA

A Phloroglucinol CoA (Certificate of Analysis) is a formal document that attests to Phloroglucinol's compliance with Phloroglucinol specifications and serves as a tool for batch-level quality control.

Phloroglucinol CoA mostly includes findings from lab analyses of a specific batch. For each Phloroglucinol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Phloroglucinol may be tested according to a variety of international standards, such as European Pharmacopoeia (Phloroglucinol EP), Phloroglucinol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Phloroglucinol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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