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Pilocarpine Hydrochloride

LGM Pharma Pilocarpine Hydrochloride

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Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

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Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

16 API Suppliers, 8 USDMF, 3 CEP/COS, 1 JDMF, 1 KDMF, 8 NDC API, 8 Listed Suppliers, $ API Reference Price

16 API Suppliers
8 USDMF
3 CEP/COS
1 JDMF
1 KDMF
8 NDC API
8 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

26 Drugs in Development

26 Drugs in Development

FINISHED DOSAGE FORMULATIONS

67 FDF Dossiers, 29 FDA Orange Book, 23 Europe, 4 Canada, 6 Australia, 4 South Africa, 1 Listed Dossiers

67 FDF Dossiers
29 FDA Orange Book
23 Europe
4 Canada
6 Australia
4 South Africa
1 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SOLUTION;OPHTHALMIC - 1%, SOLUTION;OPHTHALMIC - 2%, SOLUTION;OPHTHALMIC - 4%, TABLET;ORAL - 5MG, TABLET;ORAL - 7.5MG

drugProductComposition
SOLUTION;OPHTHALMIC - 1%
SOLUTION;OPHTHALMIC - 2%
SOLUTION;OPHTHALMIC - 4%
TABLET;ORAL - 5MG
TABLET;ORAL - 7.5MG

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 2 Seqens, 4 DKSH, 6 Gangwal Healthcare, 1 Pfanstiehl, 1 ACG Worldwide, 9 Actylis, 1 Aeon Procare, 3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 14 BASF, 10 Corel Pharma Chem, 2 DFE Pharma, 2 Finar, 7 Gangwal Chemicals, 7 Ideal Cures Pvt Ltd, 18 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 5 Microlex e.U, 2 Nomisma Healthcare, 2 Novo Excipients, 1 Pharmatrans-Sanaq, 1 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 12 Roquette, 6 Seppic, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 9 Sigachi Industries, 2 The Dow Chemical Company, 1 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

52 Coating Systems & Additives, 28 Controlled & Modified Release, 22 Fillers, Diluents & Binders, 18 Thickeners and Stabilizers, 17 Direct Compression, 11 Granulation, 10 Topical, 10 Film Formers & Plasticizers, 10 Co-Processed Excipients, 8 Parenteral, 8 Lubricants & Glidants, 7 Solubilizers, 7 Disintegrants & Superdisintegrants, 5 Taste Masking, 5 Empty Capsules, 5 API Stability Enhancers, 4 Coloring Agents, 4 Vegetarian Capsules, 3 Emulsifying Agents, 3 Chewable & Orodispersible Aids, 2 Rheology Modifiers

DIGITAL CONTENT

25 NEWS #PharmaBuzz

media
25 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

3 US Medicaid Prescriptions, 21 Finished Drug Prices

globalSalesInformation
3 US Medicaid Prescriptions
21 Finished Drug Prices

MARKET PLACE

23 APIs, 2 FDF Dossiers

marketPlace
23 APIs
2 FDF Dossiers

PATENTS & EXCLUSIVITIES

10 US Patents, 3 US Exclusivities

patents
10 US Patents
3 US Exclusivities

REF. STANDARDS & IMPURITIES

2 EDQM , 2 USP , 2 Others

otherSolutions
2 EDQM
2 USP
2 Others

LGM Pilocarpine Hydrochloride

Synopsis

ACTIVE PHARMA INGREDIENTS

16

API Suppliers

8

USDMF

3

CEP/COS

CEP/COS Certifications

1

JDMF

0

EU WC

1

KDMF

8

NDC API

0

VMF

8

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 6,929

MARKET PLACE

23

API

2

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

67

FDF Dossiers

29

FDA Orange Book

FDA (Orange Book)

23

Europe

4

Canada

6

Australia

4

South Africa

1

Listed Dossiers

26DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

2

EDQM

2

USP

0

JP

2

Others

PATENTS & EXCLUSIVITIES

10

US Patents

3

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

25

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

494,518

Annual Reports (USD Million)

NA

Finished Drug Prices

142 RELATED EXCIPIENT COMPANIES

239EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 54-71-7, (+)-pilocarpine hydrochloride, Pilocarpine hcl, Almocarpine, Salagen, Adsorbocarpine

Molecular Formula

C₁₁H₁₇ClN₂O₂

Molecular Weight

244.72 g/mol

InChI Key

RNAICSBVACLLGM-GNAZCLTHSA-N

FDA UNII

0WW6D218XJ

Pilocarpine Hydrochloride

A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.

1 2D Structure

Pilocarpine Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one;hydrochloride

2.1.2 InChI

InChI=1S/C11H16N2O2.ClH/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;/h5,7-8,10H,3-4,6H2,1-2H3;1H/t8-,10-;/m0./s1

2.1.3 InChI Key

RNAICSBVACLLGM-GNAZCLTHSA-N

2.1.4 Canonical SMILES

CCC1C(COC1=O)CC2=CN=CN2C.Cl

2.1.5 Isomeric SMILES

CC[C@H]1[C@H](COC1=O)CC2=CN=CN2C.Cl

2.2 Other Identifiers

2.2.1 UNII

0WW6D218XJ

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Hydrochloride, Pilocarpine

2. Isopilocarpine

3. Isoptocarpine

4. Nitrate, Pilocarpine

5. Ocusert

6. Pilocarpine

7. Pilocarpine Mononitrate, (3s-cis)-isomer

8. Pilocarpine Nitrate

9. Pilocarpine, Monohydrochloride, (3s-cis)-isomer

10. Salagen

2.3.2 Depositor-Supplied Synonyms

1. 54-71-7

2. (+)-pilocarpine Hydrochloride

3. Pilocarpine Hcl

4. Almocarpine

5. Salagen

6. Adsorbocarpine

7. Pilocarpal

8. Pilocar

9. Pilocar Smp

10. Pilocarpine Monohydrochloride

11. Pilomiotin

12. Pilovisc

13. Pilocel

14. Sno Pilo

15. Mistura P

16. Pilocarpine Muriate

17. Epicar

18. Mi-pilo Ophth Sol

19. Pilopine Hs

20. Vistacarpin N

21. Pilocarpine, Hydrochloride

22. Spersacarpine Hydrochloride

23. Pilokarpin Monohydrochloride

24. Pilopine

25. Pilocarpine Chloride

26. Pilocarpine (hydrochloride)

27. Pilo

28. Pilocarpinum Muriaticum

29. Pilocarpine, Monohydrochloride

30. Pilocarpine Hydrochlororide

31. Mls000069454

32. 0ww6d218xj

33. Isoptocarpine

34. (3s,4r)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one;hydrochloride

35. Nsc5746

36. Smr000059053

37. Isopto Carpine

38. Isopto-carpine

39. Ami-pilo

40. Amistura P

41. 2(3h)-furanone, 3-ethyldihydro-4-((1-methyl-1h-imidazol-5-yl)methyl)-, Monohydrochloride, (3s,4r)-

42. 2(3h)-furanone, 3-ethyldihydro-4-((1-methyl-1h-imidazol-5-yl)methyl)-, Monohydrochloride, (3s-cis)-

43. Pilopine Hs Gel

44. Nsc 5746

45. (3s,4r)-3-ethyl-4-((1-methyl-1h-imidazol-5-yl)methyl)dihydrofuran-2(3h)-one Hydrochloride

46. (3s,4r)-3-ethyl-4-[(1-methyl-1h-imidazol-5-yl)methyl]dihydrofuran-2(3h)-one Hydrochloride

47. Einecs 200-212-5

48. Unii-0ww6d218xj

49. Pilocarpine-hcl

50. Ai3-61859

51. Sr-01000000054

52. Mi-pilo

53. Component Of Epicar

54. Salagen (tn)

55. Sanpilo (tn)

56. Component Of Pilocar

57. Pilocarpine Hydrochloride [usp:jan]

58. Vuity

59. Pilopine Hs (tn)

60. Isopto Carpine (tn)

61. Nsc-5746

62. Pilocarpini Hydrochloridum

63. Regid855931

64. Opera_id_1616

65. Schembl41427

66. Mls000758210

67. Mls001076314

68. Mls001424017

69. Nsc 5746 Hcl

70. Pilocarpine Hcl [vandf]

71. Chembl1200330

72. Dtxsid2041096

73. Chebi:141029

74. Hy-b0726

75. Tox21_500950

76. S4231

77. Pilocarpine Hydrochloride [mi]

78. Pilocarpinum Muriaticum [hpus]

79. Akos005267231

80. Pilocarpine Hydrochloride (jp17/usp)

81. Ccg-100757

82. Lp00950

83. Nc00007

84. Pilocarpine Hydrochloride [jan]

85. (3s,4r)-3-ethyl-4-[(1-methylimidazol-5-yl)methyl]-3,4,5-trihydrofuran-2-one, C Hloride

86. Ncgc00094254-01

87. Ncgc00261635-01

88. Pilocarpine Hydrochloride [mart.]

89. Pilocarpine Hydrochloride [vandf]

90. Ac-33119

91. Pilocarpine Hydrochloride [usp-rs]

92. Pilocarpine Hydrochloride [who-dd]

93. Pilocarpine Hydrochloride [who-ip]

94. Eu-0100950

95. Sw196587-4

96. D02200

97. D91961

98. P 6503

99. Pilocarpine Hydrochloride [ep Impurity]

100. Pilocarpine Hydrochloride [ep Monograph]

101. Pilocarpine Hydrochloride [orange Book]

102. Pilocarpine Hydrochloride [usp Impurity]

103. 2(3h)-furanone, Monohydrochloride, (3s-cis)-

104. Pilocarpine Hydrochloride [usp Monograph]

105. Pilocarpini Hydrochloridum [who-ip Latin]

106. Wln: T5ovtj C2 D1- Dt5n Cnj C1 &gh

107. Sr-01000000054-3

108. Sr-01000075339-1

109. Pilocarpine Hydrochloride, >=98% (titration), Powder

110. Q23059847

111. Betoptic Pilo Component Pilocarpine Hydrochloride

112. Pilocarpine Hydrochloride Component Of Betoptic Pilo

113. Pilocarpine Hydrochloride, Meets Usp Testing Specifications

114. Pilocarpine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

115. (3s,4r)-3-ethyl-4-[(1-methyl-1h-imidazol-5-yl)methyl]oxolan-2-one Hydrochloride

116. Pilocarpine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

117. Pilocarpine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

118. (3s-cis)-3-ethyldihydro-4-[(1-methyl-1h-imidazol-5-yl)methyl]-2(3h)-furanone Hydrochloride

119. 2(3h)-furanone, 3-ethyldihydro-4-((1-methyl-1h-imidazol-5-yl)methyl)-, Hydrochloride (1:1), (3s,4r)-

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₁H₁₇ClN₂O₂
Molecular Weight	244.72 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	244.0978555 g/mol
Monoisotopic Mass	244.0978555 g/mol
Topological Polar Surface Area	44.1 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	245
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 8
Drug Name	Isopto carpine
PubMed Health	Pilocarpine
Drug Classes	Dental Agent, Direct Acting Miotic
Drug Label	Isopto Carpine (pilocarpine hydrochloride ophthalmic solution) is a cholinergic agonist prepared as a sterile topical ophthalmic solution. The active ingredient is represented by the chemical structure:Established name: pilocarpine hydrochlorideChe...
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Solution
Route	Ophthalmic
Strength	1%; 2%; 4%
Market Status	Prescription
Company	Alcon Res

2 of 8
Drug Name	Pilocarpine hydrochloride
PubMed Health	Pilocarpine
Drug Classes	Dental Agent, Direct Acting Miotic
Drug Label	Pilocarpine hydrochloride tablets contain pilocarpine hydrochloride, a cholinergic agonist for oral use. Pilocarpine hydrochloride is a hygroscopic, odorless, bitter tasting white crystal or powder, which is soluble in water and alcohol and virtually...
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	7.5mg; 5mg
Market Status	Prescription
Company	Corepharma; Roxane; Lannett; Impax Labs

3 of 8
Drug Name	Pilopine hs
Drug Label	SALAGEN Tablets contain pilocarpine hydrochloride, a cholinergic agonist for oral use. Pilocarpine hydrochloride is a hygroscopic, odorless, bitter tasting white crystal or powder which is soluble in water and alcohol and virtually insoluble in mos...
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Gel
Route	Ophthalmic
Strength	4%
Market Status	Prescription
Company	Alcon

4 of 8
Drug Name	Salagen
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	7.5mg; 5mg
Market Status	Prescription
Company	Eisai

5 of 8
Drug Name	Isopto carpine
PubMed Health	Pilocarpine
Drug Classes	Dental Agent, Direct Acting Miotic
Drug Label	Isopto Carpine (pilocarpine hydrochloride ophthalmic solution) is a cholinergic agonist prepared as a sterile topical ophthalmic solution. The active ingredient is represented by the chemical structure:Established name: pilocarpine hydrochlorideChe...
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Solution
Route	Ophthalmic
Strength	1%; 2%; 4%
Market Status	Prescription
Company	Alcon Res

6 of 8
Drug Name	Pilocarpine hydrochloride
PubMed Health	Pilocarpine
Drug Classes	Dental Agent, Direct Acting Miotic
Drug Label	Pilocarpine hydrochloride tablets contain pilocarpine hydrochloride, a cholinergic agonist for oral use. Pilocarpine hydrochloride is a hygroscopic, odorless, bitter tasting white crystal or powder, which is soluble in water and alcohol and virtually...
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	7.5mg; 5mg
Market Status	Prescription
Company	Corepharma; Roxane; Lannett; Impax Labs

7 of 8
Drug Name	Pilopine hs
Drug Label	SALAGEN Tablets contain pilocarpine hydrochloride, a cholinergic agonist for oral use. Pilocarpine hydrochloride is a hygroscopic, odorless, bitter tasting white crystal or powder which is soluble in water and alcohol and virtually insoluble in mos...
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Gel
Route	Ophthalmic
Strength	4%
Market Status	Prescription
Company	Alcon

8 of 8
Drug Name	Salagen
Active Ingredient	Pilocarpine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	7.5mg; 5mg
Market Status	Prescription
Company	Eisai

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Muscarinic Agonists

Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate. (See all compounds classified as Muscarinic Agonists.)

Miotics

Agents causing contraction of the pupil of the eye. Some sources use the term miotics only for the parasympathomimetics but any drug used to induce miosis is included here. (See all compounds classified as Miotics.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Cholinergic Muscarinic Agonists [MoA]; Cholinergic Receptor Agonist [EPC]; Cholinergic Agonists [MoA]

API SUPPLIERS

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USDMF

01

Anidro Do Brasil Extracoes Sa

Brazil

euroPLX 86 Munich

Not Confirmed

02

Boehringer Ingelheim Pharma Kg

Germany

euroPLX 86 Munich

Not Confirmed

03

Spera Nexus Inc

Japan

euroPLX 86 Munich

Not Confirmed

04

Linnea Phytochemicals

Switzerland

euroPLX 86 Munich

Not Confirmed

05

Pvp Sociedade Anonima

Brazil

euroPLX 86 Munich

Not Confirmed

06

Sourcetech Quimica Ltda

Brazil

euroPLX 86 Munich

Not Confirmed

07

Anidro Do Brasil Extracoes Sa

Brazil

euroPLX 86 Munich

Not Confirmed

08

Zhejiang Ausun Pharmaceutical Co Ltd

China

euroPLX 86 Munich

Not Confirmed

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CEP/COS

01

ANIDRO DO BRASIL EXTRACOES S.A. Par...

Brazil

BioFlorida Conference

Not Confirmed

02

SOURCETECH QUIMICA LTDA. Pindamonha...

Brazil

BioFlorida Conference

Not Confirmed

03

SPERA NEXUS, INC. Shizuoka JP

Japan

BioFlorida Conference

Not Confirmed

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JDMF

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KDMF

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NDC API

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Listed Suppliers

01

LGM Pharma

U.S.A

BioFlorida Conference

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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U.S.A

Digital Content

Pilocarpine Hydrochloride

About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.

Product Web Link

Digital Content

02

Vivatis

euroPLX 86 Munich

Not Confirmed

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Pilocarpine Hydrochloride

About the Company :

Portfolio PDF

Product Web Link

Virtual Booth

Digital Content

Website

Corporate PDF

03

Ajanta Pharma Limited

India

euroPLX 86 Munich

Not Confirmed

Ajanta Pharma Limited

India

euroPLX 86 Munich

Not Confirmed

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Post an Enquiry

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India

Digital Content

Pilocarpine HCl

About the Company : Ajanta Pharma is a specialty pharmaceutical company engaged in development, manufacture and marketing of quality finished dosages in domestic and international markets. Established...

Ajanta Pharma is a specialty pharmaceutical company engaged in development, manufacture and marketing of quality finished dosages in domestic and international markets. Established in 1973 and headquartered in Mumbai-India, we are committed to 'Serve Health Care Needs Worldwide'. Ajanta has been consistently providing high quality affordable medicines to patients in different parts of the world. We employ over 4,000 people worldwide and our products are sold in over 40 countries. Ajanta operates with 5 state-of-the art manufacturing facilities that produce high quality pharmaceutical products. We focus on commercializing unique generic products and pioneering synergistic combination products in the therapeutic areas of anti-malarial, Cardiovascular, dermatology, male erectile dysfunction, musculoskeletal, and ophthalmology. In India, we have significant presence in the fast growing specialty therapeutic segments of Cardiovascular, dermatology, ophthalmology and musculoskeletal. With primary focus on new product innovation and introduction, we have been consistently identifying unmet medical needs and introducing many first-to-market products to cater to those needs. Our products provide patient compliance and convenience over existing therapeutic options. Gaining first mover advantage, many of our brands hold leadership positions in their respective sub- therapeutic segments. Ajanta has extensive presence in many countries in Asia, Africa and Latin America with customized product portfolio to suit the needs of each country. Having successfully gone through USFDA inspection, we have started commercial operations in the US market in the first quarter of 2013. With a portfolio of 23 ANDAs which have been filed with the US FDA, we look forward to the US market to be our key growth driver in coming years. We have an advanced Research & Development Centre for finished formulations and Active Pharmaceutical Ingredient (API) synthesis of different dosage forms. ‘Advent’, our R&D centre has a team of over 300 scientists working on innovative products for various markets across the globe. We have acquired strong capabilities for developing generic formulations and process chemistry over the years. Committed to patient care since inception, our focus on specialty segments in India and simultaneous opening of new international markets has been accelerating our growth over the years. Ajanta’s team members are driven to fulfill its mission; a commitment to ‘Serving Global Healthcare needs with Empathy, Innovation & Technology’.

Portfolio PDF

Product Web Link

Digital Content

Corporate PDF

04

Amneal Pharmaceuticals

U.S.A

euroPLX 86 Munich

Not Confirmed

05

C-Squared Pharma

Ireland

euroPLX 86 Munich

Not Confirmed

06

C-Squared Pharma

Ireland

euroPLX 86 Munich

Not Confirmed

07

Guangzhou Tosun Pharmaceutical

China

euroPLX 86 Munich

Not Confirmed

08

IWAKI SEIYAKU

Japan

euroPLX 86 Munich

Not Confirmed

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API Reference Price

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LIMITED","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"6350","totalValueFC":"8578.7","currency":"EUR","unitRateINR":"714000","date":"13-Oct-2023","totalValueINR":"714000","totalValueInUsd":"8578.7","indian_port":"Madras Air","hs_no":"29397900","bill_no":"8282065","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"BASLE","supplierAddress":"BRIDGE HOUSE UNIT 2SKEHARD ROAD,T12 H2TK CORK, IRELAND","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1697135400,"product":"PILOCARPINE HYDROCHLORIDE API","address":"PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD\/ANDHRA PRADESH","supplier":"VINCHEM, INC.","supplierCountry":"UNITED STATES","foreign_port":"NEWARK, NJ","customer":"AUROBINDO PHARMA LIMITED","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"6900","totalValueFC":"6976.3","currency":"USD","unitRateINR":"580635","date":"13-Oct-2023","totalValueINR":"580635","totalValueInUsd":"6976.3","indian_port":"Hyderabad Air","hs_no":"29398000","bill_no":"8289706","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEWARK, NJ","supplierAddress":"301 MAIN STREET, PO BOX 639, CHATHAM, NJ 07928, UNITED STATESSDNF United States","customerAddress":"PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1697999400,"product":"PILOCARPINE HYDROCHLORIDE","address":"109, SHIV SMRITI CHAMBERS,","city":"MUMBAI, MAHARASHTRA","supplier":"C-SQUARED PHARMA","supplierCountry":"BRAZIL","foreign_port":"BASLE","customer":"S.ZHAVERI PHARMAKEM PVT LTD","customerCountry":"INDIA","quantity":"7.96","actualQuantity":"7.956","unit":"KGS","unitRateFc":"7800","totalValueFC":"64692.2","currency":"USD","unitRateINR":"676757.5","date":"23-Oct-2023","totalValueINR":"5384282.67","totalValueInUsd":"64692.2","indian_port":"Bombay Air","hs_no":"29392090","bill_no":"8438170","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"BASLE","supplierAddress":"BRIDGE HOUSE UNIT 2,SKEHARD ROAD, T12 H2TK CORK,IRELAND IE","customerAddress":"109, SHIV SMRITI CHAMBERS,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701369000,"product":"PILOCARPINE HCL","address":"ACME PLAZA , ANDHERI KURLA ROAD","city":"MUMBAI","supplier":"VIVATIS","supplierCountry":"BRAZIL","foreign_port":"HAMBURG - FUHLSBUETT","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"8800","totalValueFC":"88932.5","currency":"USD","unitRateINR":"740302","date":"01-Dec-2023","totalValueINR":"7403020.24","totalValueInUsd":"88932.5","indian_port":"Bombay Air","hs_no":"29397900","bill_no":"9019586","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"HAMBURG - FUHLSBUETT","supplierAddress":"GRUNER DEICH 1-320097 HAMBURGGERMANY DE","customerAddress":"ACME PLAZA , ANDHERI KURLA ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1703183400,"product":"PILOCARPINE HCL","address":"ACME PLAZA , ANDHERI KURLA ROAD","city":"MUMBAI","supplier":"VIVATIS","supplierCountry":"BRAZIL","foreign_port":"HAMBURG - FUHLSBUETT","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"8800","totalValueFC":"88615.2","currency":"USD","unitRateINR":"737661.2","date":"22-Dec-2023","totalValueINR":"7376612.32","totalValueInUsd":"88615.2","indian_port":"Bombay Air","hs_no":"29397900","bill_no":"9366845","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"HAMBURG - FUHLSBUETT","supplierAddress":"GRUNER DEICH 1-320097 HAMBURG GERMANYSDNF DE","customerAddress":"ACME PLAZA , ANDHERI KURLA ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1704652200,"product":"PILOCARPINE HYDROCHLORIDE","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"CSQUARED PHARMA LIMITED","supplierCountry":"SWITZERLAND","foreign_port":"N\/A","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"6675","totalValueFC":"101496.3","currency":"USD","unitRateINR":"562368.7","date":"08-Jan-2024","totalValueINR":"8435531","totalValueInUsd":"101496.3","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29398000","bill_no":"1000099","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710095400,"product":"PILOCARPINE HYDROCHLORIDE","address":"109, SHIV SMRITI CHAMBERS,","city":"MUMBAI, MAHARASHTRA","supplier":"C-SQUARED PHARMA","supplierCountry":"BRAZIL","foreign_port":"BASLE","customer":"S.ZHAVERI PHARMAKEM PVT LTD","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"8695","totalValueFC":"45614","currency":"USD","unitRateINR":"757518.8","date":"11-Mar-2024","totalValueINR":"3787593.75","totalValueInUsd":"45614","indian_port":"Bombay Air","hs_no":"29392090","bill_no":"2514837","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"BASLE","supplierAddress":"BRIDGE HOUSE UNIT 2,SKEHARD ROAD, T12 H2TK CORK,IRELAND IE","customerAddress":"109, SHIV SMRITI CHAMBERS,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720722600,"product":"PILOCARPINE HYDROCHLORIDE PH. EUR.:-FOR EXAMINATION,TEST ORANALYSIS PURPOSE ONLY","address":"COMMERCE HOUSE V,BESIDES VODAFONE","city":"AHMEDABAD, GUJARAT. INDIA.","supplier":"C-SQUARED PHARMA","supplierCountry":"BRAZIL","foreign_port":"BASLE","customer":"ACULIFE HEALTHCARE","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"7000","totalValueFC":"9443.4","currency":"USD","unitRateINR":"789381","date":"12-Jul-2024","totalValueINR":"789380.95","totalValueInUsd":"9443.4","indian_port":"Ahmedabad Air","hs_no":"29397900","bill_no":"4460770","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"BASLE","supplierAddress":"BRIDGE HOUSE UNIT 2SKEHARD ROAD,T12 H2TK CORK IRELAND","customerAddress":"COMMERCE HOUSE V,BESIDES VODAFONE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723228200,"product":"PILOCARPINE HYDROCHLORIDE USP","address":"98, GOVT.INDUSTRIAL AREA,","city":"MUMBAI.","supplier":"VIVATIS","supplierCountry":"BRAZIL","foreign_port":"HAMBURG - FUHLSBUETT","customer":"AJANTA PHARMA LIMITED","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"9500","totalValueFC":"19169.6","currency":"USD","unitRateINR":"803957.2","date":"10-Aug-2024","totalValueINR":"1607914.37","totalValueInUsd":"19169.6","indian_port":"Bombay Air","hs_no":"29397900","bill_no":"4988193","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"HAMBURG - FUHLSBUETT","supplierAddress":"GRUNER DEICH 1-3 20097 HAMBURG MFG:SOURTECH QUIMICA LTDA,BRAZILSDNF Germany","customerAddress":"98, GOVT.INDUSTRIAL AREA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725301800,"product":"PILOCARPINE HYDROCHLORIDE MILLED PILOCARPINE HYDROCHLORIDE MILLED","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"VIVATIS","supplierCountry":"BRAZIL","foreign_port":"HAMBURG","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"8900","totalValueFC":"135170.8","currency":"USD","unitRateINR":"755165","date":"03-Sep-2024","totalValueINR":"11327475","totalValueInUsd":"135170.8","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29397900","bill_no":"5402148","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"HAMBURG","supplierAddress":"GRUNER DEICH 1-3 HAMBURG 290097 DE","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725474600,"product":"ALKALOIDS,SOLID,N,O,S(PILOCARPINE HYDROCHLORIDE)","address":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"SOURCETECH QUIMICA LTDA","supplierCountry":"BRAZIL","foreign_port":"SAO PAULO","customer":"APL HEALTHCARE","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"6900","totalValueFC":"34931.8","currency":"USD","unitRateINR":"585465","date":"05-Sep-2024","totalValueINR":"2927325","totalValueInUsd":"34931.8","indian_port":"APIIC MULTI PRODUCT SEZ NAIDUPET AP","hs_no":"29398000","bill_no":"5434022","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"SAO PAULO","supplierAddress":"ROD VEREADOR ABEL FABRICIO DIAS 3 430 PINDAMONHANGABA SP Sao Paulo, SDNF Brazil","customerAddress":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725561000,"product":"PILOCARPINE HYDROCHLORIDE","address":"109, SHIV SMRITI CHAMBERS,","city":"MUMBAI, MAHARASHTRA","supplier":"C-SQUARED PHARMA","supplierCountry":"BRAZIL","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"S.ZHAVERI PHARMAKEM PVT LTD","customerCountry":"INDIA","quantity":"12.00","actualQuantity":"12","unit":"KGS","unitRateFc":"7800","totalValueFC":"94827.3","currency":"USD","unitRateINR":"662220","date":"06-Sep-2024","totalValueINR":"7946640","totalValueInUsd":"94827.3","indian_port":"Bombay Air","hs_no":"29392090","bill_no":"5464225","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"BRIDGE HOUSE UNIT 2, SKEHARD ROAD, T12 H2TK CORK, IRELAND IE IE","customerAddress":"109, SHIV SMRITI CHAMBERS,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726857000,"product":"(FOC) - PILOCARPINE HYDROCHLORIDE - A69905 - VC-2205","address":"REGD. OFFICE: NO. 16\/2,","city":"BANGALORE, KARNATAKA","supplier":"C-SQUARED PHARMA","supplierCountry":"BRAZIL","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"SOMERSET THERAPEUTICS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"6978","totalValueFC":"359134.9","currency":"USD","unitRateINR":"601918.8","date":"21-Sep-2024","totalValueINR":"30095942.4","totalValueInUsd":"359134.9","indian_port":"Bangalore Air","hs_no":"29397900","bill_no":"5732357","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"BRIDGE HOUSE UNIT 2 SHEHARD ROAD T1 2 H2TK CORK IRELAND (IRL) Dublin, , Ireland Ireland","customerAddress":"REGD. OFFICE: NO. 16\/2,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728066600,"product":"PILOCARPINE NITRATE USP\/IP","address":"142-48 S.V.ROAD,","city":"MUMBAI, MAHARASHTRA","supplier":"VIVATIS","supplierCountry":"BRAZIL","foreign_port":"HAMBURG - FUHLSBUETT","customer":"FDC","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"6000","totalValueFC":"151470","currency":"USD","unitRateINR":"509100","date":"05-Oct-2024","totalValueINR":"12727500","totalValueInUsd":"151470","indian_port":"Bombay Air","hs_no":"29397900","bill_no":"5968562","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"HAMBURG - FUHLSBUETT","supplierAddress":"GRUNER DEICH 1-320097 HAMBURG SDNF SDNF GERMANY","customerAddress":"142-48 S.V.ROAD,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - SOLUTION;OPHTHALMIC - 1%

USFDA APPLICATION NUMBER - 200890

DOSAGE - SOLUTION;OPHTHALMIC - 2%

USFDA APPLICATION NUMBER - 200890

DOSAGE - SOLUTION;OPHTHALMIC - 4%

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DOSAGE - TABLET;ORAL - 5MG

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DOSAGE - TABLET;ORAL - 7.5MG

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01

ABBVIE

U.S.A

Pharma Manufacturing 2024

Not Confirmed

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Patent Expiration Date : 2039-04-24

PILOCARPINE HYDROCHLORIDE

US Patent Number : 11285134

Drug Substance Claim :

Drug Product Claim :

Application Number : 214028

Patent Use Code : U-3562

Patent Use Description :

Patent Expiration Date : 2039-04-24

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02

ABBVIE

U.S.A

Pharma Manufacturing 2024

Not Confirmed

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Patent Expiration Date : 2039-04-24

PILOCARPINE HYDROCHLORIDE

US Patent Number : 11285134

Drug Substance Claim :

Drug Product Claim :

Application Number : 214028

Patent Use Code : U-3561

Patent Use Description :

Patent Expiration Date : 2039-04-24

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03

ABBVIE

U.S.A

Pharma Manufacturing 2024

Not Confirmed

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Patent Expiration Date : 2039-04-24

PILOCARPINE HYDROCHLORIDE

US Patent Number : 10610518

Drug Substance Claim :

Drug Product Claim :

Application Number : 214028

Patent Use Code : U-3561

Patent Use Description :

Patent Expiration Date : 2039-04-24

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04

ABBVIE

U.S.A

Pharma Manufacturing 2024

Not Confirmed

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Patent Expiration Date : 2039-04-24

PILOCARPINE HYDROCHLORIDE

US Patent Number : 10610518

Drug Substance Claim :

Drug Product Claim :

Application Number : 214028

Patent Use Code : U-3562

Patent Use Description :

Patent Expiration Date : 2039-04-24

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05

ABBVIE

U.S.A

Pharma Manufacturing 2024

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Patent Expiration Date : 2039-04-24

PILOCARPINE HYDROCHLORIDE

US Patent Number : 10610518

Drug Substance Claim :

Drug Product Claim :

Application Number : 214028

Patent Use Code : U-3252

Patent Use Description :

Patent Expiration Date : 2039-04-24

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06

ABBVIE

U.S.A

Pharma Manufacturing 2024

Not Confirmed

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Patent Expiration Date : 2039-04-24

PILOCARPINE HYDROCHLORIDE

US Patent Number : 11285134

Drug Substance Claim :

Drug Product Claim :

Application Number : 214028

Patent Use Code : U-3252

Patent Use Description :

Patent Expiration Date : 2039-04-24

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07

ORASIS PHARMS

PILOCARPINE HYDROCHLORIDE

Pharma Manufacturing 2024

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08

ORASIS PHARMS

PILOCARPINE HYDROCHLORIDE

Pharma Manufacturing 2024

Not Confirmed

09

ORASIS PHARMS

PILOCARPINE HYDROCHLORIDE

Pharma Manufacturing 2024

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10

ORASIS PHARMS

PILOCARPINE HYDROCHLORIDE

Pharma Manufacturing 2024

Not Confirmed

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