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    Also known as: 53251-94-8, Dicetel, Pinaverium bromide [inn], Lat-1717, Pinaverium bromide (inn), Morpholinium, 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, bromide (1:1)
    Molecular Formula
    C26H41Br2NO4
    Molecular Weight
    591.4  g/mol
    InChI Key
    IKGXLCMLVINENI-UHFFFAOYSA-M
    Pinaverium Bromide
    Pinaverium Bromide is an orally available bromide salt form of pinaverium, a calcium channel blocker (CCB) with antispasmodic activity. Upon oral administration, pinaverium blocks the voltage-dependent calcium channels and inhibits calcium ion influx into the smooth muscle cells located in the gastrointestinal (GI) tract. This prevents smooth muscle contraction and relaxes the GI tract. In addition, pinaverium may both reduce bowel uptake of and facilitate the function of locally active, co-administered drugs.
    1 2D Structure

    Pinaverium Bromide

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-2-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium;bromide
    2.1.2 InChI
    InChI=1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1
    2.1.3 InChI Key
    IKGXLCMLVINENI-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC)C.[Br-]
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. 4-(6-bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium Bromide

    2. Dicetel

    3. Eldicet

    4. Pinaverium

    2.2.2 Depositor-Supplied Synonyms

    1. 53251-94-8

    2. Dicetel

    3. Pinaverium Bromide [inn]

    4. Lat-1717

    5. Pinaverium Bromide (inn)

    6. Morpholinium, 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, Bromide (1:1)

    7. Pinaverii Bromidum

    8. 4-(2-bromo-4,5-dimethoxybenzyl)-4-(2-(2-(6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethoxy)ethyl)morpholin-4-ium Bromide

    9. Bromuro De Pinaverio

    10. Bromure De Pinaverium

    11. Lat 1717

    12. Pinaverii Bromidum [inn-latin]

    13. Bromure De Pinaverium [inn-french]

    14. Bromuro De Pinaverio [inn-spanish]

    15. 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-2-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium;bromide

    16. 4-(6-bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium Bromide

    17. Ncgc00181763-01

    18. Einecs 258-450-0

    19. 7scf54h12j

    20. Unii-7scf54h12j

    21. Pinaveriumbromide-d4

    22. Dsstox_cid_28540

    23. Dsstox_rid_82812

    24. Dsstox_gsid_48614

    25. Schembl25474

    26. Morpholinium, 4-(2-bromo-4,5-dimethoxy)benzyl-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)-, Bromide

    27. Chembl1909298

    28. Dtxsid2048614

    29. 4-[(2-bromo-4,5-dimethoxy-phenyl)methyl]-4-[2-[2-[(1s,5s)-6,6-dimethylnorpinan-2-yl]ethoxy]ethyl]morpholin-4-ium Bromide

    30. Bcp21168

    31. Tox21_112949

    32. Mfcd01713435

    33. Akos015918115

    34. Gs-6842

    35. 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]-hept-2-yl)ethoxy]ethyl]morpholinium Bromide

    36. Cas-53251-94-8

    37. Hy-111613

    38. Cs-0088569

    39. Ft-0673906

    40. P2753

    41. D07094

    42. Lat 1717; Lat-1717; Lat1717

    43. A870784

    44. Q27268790

    45. 4-(2-bromo-4,5-dimethoxybenzyl)-4-{2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl}morpholin-4-ium Bromide

    46. 4-[(2-bromo-4,5-dimethoxy-phenyl)methyl]-4-[2-[2-(6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]-1-oxa-4-azoniacyclohexane Bromide

    47. 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-(2-{6,6-dimethylbicyclo[3.1.1]heptan-2-yl}ethoxy)ethyl]morpholin-4-ium Bromide

    48. Morpholinium,4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, Bromide

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 591.4 g/mol
    Molecular Formula C26H41Br2NO4
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count10
    Exact Mass591.13818 g/mol
    Monoisotopic Mass589.14023 g/mol
    Topological Polar Surface Area36.9 Ų
    Heavy Atom Count33
    Formal Charge0
    Complexity596
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count3
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Calcium Channel Blockers

    A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

    Parasympatholytics

    Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

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S.A","customerCountry":"COLOMBIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"194","totalValueFC":"4661.1","currency":"USD","unitRateINR":15564.4,"date":"19-Jun-2024","totalValueINR":"389110","totalValueInUsd":"4661.1","indian_port":"Hyderabad Air","hs_no":"29239000","bill_no":"1787629","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719253800,"product":"PINAVERIUM BROMIDE","address":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N","city":"HYDERABAD,TELANGANA","supplier":"AURORE LIFE SCIENCES","supplierCountry":"INDIA","foreign_port":"BUENAVENTURA","customer":"MEGALABS COLOMBIA SAS","customerCountry":"COLOMBIA","quantity":"180.00","actualQuantity":"180","unit":"KGS","unitRateFc":"170","totalValueFC":"30178.7","currency":"USD","unitRateINR":13996.111111111111,"date":"25-Jun-2024","totalValueINR":"2519300","totalValueInUsd":"30178.7","indian_port":"Hyderabad ICD","hs_no":"29239000","bill_no":"1939495","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726684200,"product":"PINAVERIUM BROMIDE MFG DATE:NOV-2023,EXPIRY DATE:OCT-2028 BATCH NO:PIN2311018","address":"PLOT NO.1-A SEC-16A","city":"NOIDA (U.P) INDIA","supplier":"JUBILANT PHARMOVA","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"TO THE ORDER OF\\'","customerCountry":"TURKEY","quantity":"482.00","actualQuantity":"482","unit":"KGS","unitRateFc":"250","totalValueFC":"117907.5","currency":"USD","unitRateINR":20499.575124481329,"date":"19-Sep-2024","totalValueINR":"9880795.21","totalValueInUsd":"117907.5","indian_port":"Bangalore Air","hs_no":"29239000","bill_no":"4155554","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"PLOT NO.1-A SEC-16A, NOIDA (U.P) INDIA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727029800,"product":"PINAVERIUM BROMIDEB\/NO: PBR2311048MFG DT: NOV-2023,RETEST DAT: OCT-2027","address":"PLOT NO.1-A SEC-16A","city":"NOIDA (U.P) INDIA","supplier":"JUBILANT PHARMOVA","supplierCountry":"INDIA","foreign_port":"BARRANQUILLA","customer":"LABORATORIOS INCOBRA S.A","customerCountry":"COLOMBIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"350","totalValueFC":"1631.3","currency":"USD","unitRateINR":27340.420000000002,"date":"23-Sep-2024","totalValueINR":"136702.1","totalValueInUsd":"1631.3","indian_port":"Bangalore Air","hs_no":"29239000","bill_no":"4254789","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"PLOT NO.1-A SEC-16A, NOIDA (U.P) INDIA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1632076200,"product":"PINAVERIUM BROMIDE 25KG M2I FR","address":"UNIT NOS. 3&4, CORPORATE PARK,SION-TROMBAY ROAD, CHEMBUR,","city":"MUMBAI. MAHARASHTRA","supplier":"ABBOTT LABORATORIES","supplierCountry":"FRANCE","foreign_port":"#N\/A","customer":"ABBOTT LABORATORIES","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"136.4","totalValueFC":"3449.1","currency":"USD","unitRateINR":"10148.2","date":"20-Sep-2021","totalValueINR":"253704","totalValueInUsd":"3449.1","indian_port":"BOMBAY AIR","hs_no":"29349990","bill_no":"5508031","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"UNIT NOS. 3&4, CORPORATE PARK,SION-TROMBAY ROAD, CHEMBUR,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699900200,"product":"(RE-IMPORT) PINAVERIUM BROMIDE","address":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N","city":"HYDERABAD,TELANGANA","supplier":"M\/S.MOLECULAS FINAS DE MEXICO SA DE CV","supplierCountry":"INDIA","foreign_port":"MANZANILLO","customer":"AURORE LIFE SCIENCES","customerCountry":"INDIA","quantity":"3100.00","actualQuantity":"3100","unit":"KGS","unitRateFc":"159","totalValueFC":"498103.7","currency":"USD","unitRateINR":"13379.9","date":"14-Nov-2023","totalValueINR":"41477535","totalValueInUsd":"498103.7","indian_port":"JNPT","hs_no":"29349990","bill_no":"8765406","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MANZANILLO","supplierAddress":"CARRETERA TEXCOCO LECHERIA KM 23.5S\/N INT.BDGA 4 101,LA MAGDALENA PANOAYA TEXC OCO ESTADO DE MEXICO CP:5 MEXICO","customerAddress":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N"}]
    21-Jan-2021
    23-Sep-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    Finished Drug Prices

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    01

    Brand Name : Dicetel

    U.S.A
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    Medlab Asia & Asia Health
    Not Confirmed

    Brand Name : Dicetel

    U.S.A
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    Medlab Asia & Asia Health
    Not Confirmed

    Viatris Pharma GmbH

    Pinaverium Bromide

    Dosage Form : Film-Coated Tablets

    Dosage Strength : 50mg

    Price Per Pack (Euro) : 9.39

    Published in :

    Country : Switzerland

    RX/OTC/DISCN : Class B

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    02

    Brand Name : Dicetel

    U.S.A
    arrow
    Medlab Asia & Asia Health
    Not Confirmed

    Brand Name : Dicetel

    U.S.A
    arrow
    Medlab Asia & Asia Health
    Not Confirmed

    Viatris Pharma GmbH

    Pinaverium Bromide

    Dosage Form : Film-Coated Tablets

    Dosage Strength : 50mg

    Price Per Pack (Euro) : 16.49

    Published in :

    Country : Switzerland

    RX/OTC/DISCN : Class B

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    03

    Brand Name : Dicetel

    Country
    arrow
    Medlab Asia & Asia Health
    Not Confirmed

    Brand Name : Dicetel

    Country
    arrow
    Medlab Asia & Asia Health
    Not Confirmed

    SOLVAY PHARMA SpA

    Pinaverium Bromide

    Dosage Form :

    Dosage Strength : 30 Cpr Riv 50 Mg  

    Price Per Pack (Euro) : 12.04

    Published in :

    Country : Italy

    RX/OTC/DISCN : Class C

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    Market Place

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    APIs

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    india-flag.png
    Pinaverium Bromide (5 kg) API needed in India [ENA19592]
    A contract manufacturing organization (CMO) that focuses on manufacturing of various nutraceutical & pharmaceutical finished formulations is looking for suppliers of Pinaverium Bromide (5 kg) API for commercial purposes. The suppliers must support this enquiry with CoA.
    28 May 2024

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    28 May 2024

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    28 May 2024

    turkeypng-1602828403png-1622460951png-1622462103.png
    Various APIs needed in Turkey [ENA15043]
    A company that focuses on research, development, manufacturing and distribution of finished formulations, OTC products & cosmetics is looking for suppliers of Various APIs for commercial purpose. The required quantity is 100 kg for each. The suppliers must support this enquiry with DMF, GMP & CoA. 1. Pinaverium Bromide API 2. Ivermectin API
    15 Sep 2022

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    15 Sep 2022

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    Reply Comment (13)

    15 Sep 2022

    Algeria.png
    Various APIs needed in Algeria [ENA10557]
    A company that deals in various pharmaceutical products is looking for suppliers of Various APIs for commercial purposes. The suppliers must support this enquiry with CEP/ DMF. 1. Ibuprofen (800 kg/ annum) API 2. Pseudoephedrine HCl (400 kg/ annum) API 3. Omeprazole (1 MT/ annum) Pellets 4. Paracetamol (1 MT/ annum) API 5. Diclofenac Potassium (800 kg/ annum) API 6. Diclofenac Sodium (800 kg/ annum) API 7. Nifuroxazide (650 kg/ annum) API 8. Trimebutine Maleate (750 kg/ annum) API 9. Ketotifen (600 kg/ annum) API 10. Mebeverine HCl (700 kg/ annum) API 11. Celecoxib (550 kg/ annum) API 12. Naproxen Sodium (850 kg/ annum) API 13. Domperidone (600 kg/ annum) API 14. Pinaverium Bromide (700 kg/ annum) API 15. Dexchlorpheniramine Maleate (600 kg/ annum) API
    02 Jun 2021

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    02 Jun 2021

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    Reply Comment (17)

    02 Jun 2021

    Colombia.png
    Pinaverium Bromide & Rifaximin APIs needed in Colombia [ENA10070]
    A company that deals in dietary supplements and phytotherapeutic products oriented to the treatment of various pathologies is looking for suppliers of Pinaverium Bromide (14 kg) & EP Grade Rifaximin (35 kg) APIs for commercial purposes. The suppliers must support this enquiry with DMF and CoA.
    29 Mar 2021

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    29 Mar 2021

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    Reply Comment (10)

    29 Mar 2021

    turkeypng-1602828403png-1622460951png-1622462103.png
    Simethicone & Pinaverium Bromide APIs needed in Turkey [ENA08432]
    A pioneer in the international active pharmaceutical ingredient market is looking for suppliers of Simethicone & Pinaverium Bromide APIs for new development. The suppliers must support this enquiry with DMF, GMP & EU-WC.
    02 Sep 2020

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    02 Sep 2020

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    Reply Comment (9)

    02 Sep 2020

    india-flag.png
    Pinaverium API needed in India [ENA04486]
    A company engrossed in marketing & distribution of sterile liquid injectables and oral solid forms is looking for suppliers Pinaverium API.
    26 Jun 2019

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    26 Jun 2019

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    Reply Comment (6)

    26 Jun 2019

    Market Place
    Enquiry// Pinaverium Bromide, Norethisterone Acetate & Dehydrated alcohol needed in Colombia [ENA01542]
    A leading pharmaceutical organisation of the health sector that develops innovative pharmaceutical solution under a sustainable model and permanent internationalization is looking for the suppliers of the following products for domestic consumption: 1. Pinaverium Bromide 2. Norethisterone Acetate 3. Dehydrated Alcohol
    17 Aug 2018

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    17 Aug 2018

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    Reply Comment (5)

    17 Aug 2018

    Market Place
    Enquiry// Pinaverium Bromide, Imatinib and other APIs needed for Indian market [ENA00981]
    Farma Source, a representative agent company duly authorised by the buyer to support sourcing their APIs requirement is looking for suppliers of following APIs with COA and GMP certificate: 1) Pinaverium Bromide 2) Imatinib 3) Erlotinib 4) Sorafenib 5) Lenalidomide The products are needed in commercial quantities. Interested suppliers should contact Mahesh Kaval via Email: maheshk@farma-source.com or Tel: +91 9967036882.
    06 Jun 2018

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    06 Jun 2018

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    Reply Comment (1)

    06 Jun 2018

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