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Chemistry

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Also known as: Domar, 52463-83-9, Pinazepam [inn], Zami 905, Duna, Z-905
Molecular Formula
C18H13ClN2O
Molecular Weight
308.8  g/mol
InChI Key
MFZOSKPPVCIFMT-UHFFFAOYSA-N
FDA UNII
5286RBZ882

Pinazepam
1 2D Structure

Pinazepam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-chloro-5-phenyl-1-prop-2-ynyl-3H-1,4-benzodiazepin-2-one
2.1.2 InChI
InChI=1S/C18H13ClN2O/c1-2-10-21-16-9-8-14(19)11-15(16)18(20-12-17(21)22)13-6-4-3-5-7-13/h1,3-9,11H,10,12H2
2.1.3 InChI Key
MFZOSKPPVCIFMT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C#CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
2.2 Other Identifiers
2.2.1 UNII
5286RBZ882
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7-chloro-5-phenyl-1-propargyl-1,4-benzodiazepin-2- One

2. Domar

3. Duna

4. Propazepam

5. Z-905

2.3.2 Depositor-Supplied Synonyms

1. Domar

2. 52463-83-9

3. Pinazepam [inn]

4. Zami 905

5. Duna

6. Z-905

7. 7-chloro-1-propargyl-5-phenyl-2h-1,4-benzodiazepin-2-one

8. 7-chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-2h-1,4-benzodiazepin-2-one

9. 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-

10. Pinazepam (inn)

11. 7-chloro-2,3-dihydro-5-phenyl-1-propargyl-1h-1,4-benzodiazepin-2-one

12. 2h-1,4-benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-1-(2-propynyl)-

13. 5286rbz882

14. Pinazepamum

15. Pinazepamum [inn-latin]

16. Einecs 257-934-9

17. Brn 0758533

18. Dea No. 2883

19. Unii-5286rbz882

20. Domar (tn)

21. 7-chloro-5-phenyl-1-prop-2-ynyl-3h-1,4-benzodiazepin-2-one

22. Pinazepam [mi]

23. Pinazepam [mart.]

24. Pinazepam [who-dd]

25. Schembl155928

26. Chembl1213352

27. Dtxsid3023475

28. Chebi:135315

29. Db13335

30. D07314

31. Q7194856

32. 7-chloro-5-phenyl-1-prop-2-ynyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

33. 7-chloro-5-phenyl-1-(2-propynyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one #

34. 7-chloro-5-phenyl-1-(prop-2-yn-1-yl)-2,3-dihydro-1h-1,4-benzodiazepin-2-one

35. 7-chloro-5-phenyl-1-prop-2-yn-1-yl-1,3-dihydro-2h-1,4-benzodiazepin-2-one

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 308.8 g/mol
Molecular Formula C18H13ClN2O
XLogP33.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass308.0716407 g/mol
Monoisotopic Mass308.0716407 g/mol
Topological Polar Surface Area32.7 Ų
Heavy Atom Count22
Formal Charge0
Complexity501
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)


4.2 ATC Code

N - Nervous system

N05 - Psycholeptics

N05B - Anxiolytics

N05BA - Benzodiazepine derivatives

N05BA14 - Pinazepam


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ABOUT THIS PAGE

Pinazepam Manufacturers

A Pinazepam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pinazepam, including repackagers and relabelers. The FDA regulates Pinazepam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pinazepam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Pinazepam manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Pinazepam Suppliers

A Pinazepam supplier is an individual or a company that provides Pinazepam active pharmaceutical ingredient (API) or Pinazepam finished formulations upon request. The Pinazepam suppliers may include Pinazepam API manufacturers, exporters, distributors and traders.

click here to find a list of Pinazepam suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Pinazepam WC

A Pinazepam written confirmation (Pinazepam WC) is an official document issued by a regulatory agency to a Pinazepam manufacturer, verifying that the manufacturing facility of a Pinazepam active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Pinazepam APIs or Pinazepam finished pharmaceutical products to another nation, regulatory agencies frequently require a Pinazepam WC (written confirmation) as part of the regulatory process.

click here to find a list of Pinazepam suppliers with Written Confirmation (WC) on PharmaCompass.

Pinazepam GMP

Pinazepam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pinazepam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pinazepam GMP manufacturer or Pinazepam GMP API supplier for your needs.

Pinazepam CoA

A Pinazepam CoA (Certificate of Analysis) is a formal document that attests to Pinazepam's compliance with Pinazepam specifications and serves as a tool for batch-level quality control.

Pinazepam CoA mostly includes findings from lab analyses of a specific batch. For each Pinazepam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pinazepam may be tested according to a variety of international standards, such as European Pharmacopoeia (Pinazepam EP), Pinazepam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pinazepam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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