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    Also known as: 14538-56-8, Piperazate, Pinrou, Phosphoric acid;piperazine, Piperazine, phosphate (1:1), Piperazine phosphate anhydrous
    Molecular Formula
    C4H13N2O4P
    Molecular Weight
    184.13  g/mol
    InChI Key
    NQQWFVUVBGSGQN-UHFFFAOYSA-N
    FDA UNII
    P7S1V82385
    Piperazine
    An anti-nematodal agent effective against the intestinal nematodes ASCARIS LUMBRICOIDES (roundworm) and ENTEROBIUS VERMICULARIS (pinworm, threadworm). It produces a neuromuscular block leading to flaccid muscle paralysis in susceptible worms, which are then dislodged from the gut and expelled in feces.
    1 2D Structure

    Piperazine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    phosphoric acid;piperazine
    2.1.2 InChI
    InChI=1S/C4H10N2.H3O4P/c1-2-6-4-3-5-1;1-5(2,3)4/h5-6H,1-4H2;(H3,1,2,3,4)
    2.1.3 InChI Key
    NQQWFVUVBGSGQN-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CNCCN1.OP(=O)(O)O
    2.2 Other Identifiers
    2.2.1 UNII
    P7S1V82385
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 1,4 Diazacyclohexane

    2. 1,4 Piperazine

    3. 1,4-diazacyclohexane

    4. 1,4-piperazine

    5. Piperazine

    6. Piperazine Diacetate

    7. Piperazine Hexahydrate

    8. Piperazine Hydrate

    9. Piperazine Hydrobromide

    10. Piperazine Monohydrochloride

    11. Piperazine Phosphate (1:1)

    12. Piperazine Phosphate Anhydrous

    13. Piperazine Salt

    14. Piperazine Sulfate

    15. Piperazine Tartrate

    16. Piperazine Tartrate (1:1), (r-(r*,r*))-isomer

    17. Piperazine Tartrate, (r-(r*,r*))-isomer

    18. Piperazinium Oleate

    19. Pripsen

    2.3.2 Depositor-Supplied Synonyms

    1. 14538-56-8

    2. Piperazate

    3. Pinrou

    4. Phosphoric Acid;piperazine

    5. Piperazine, Phosphate (1:1)

    6. Piperazine Phosphate Anhydrous

    7. Piperazine Phosphate Monohydrate

    8. P7s1v82385

    9. Piperazine, Phosphate

    10. Anthalazine Phosphate

    11. Mfcd00036382

    12. Phosphoric Acid; Piperazine

    13. Einecs 217-775-8

    14. Piperazine, Compound With Phosphoric Acid

    15. Unii-p7s1v82385

    16. Einecs 238-572-0

    17. Piperverm

    18. Piperazine Orthophosphate

    19. Phosphoric Acid,piperazine

    20. Tasnon (tabl.)

    21. Ec 217-775-8

    22. Piperazine Hydrogen Phosphate

    23. Schembl227947

    24. Piperazine Monophosphate

    25. Chembl2219733

    26. Dtxsid70932581

    27. Piperazine Phosphate [mi]

    28. Phosphoric Acid--piperazine (1/1)

    29. Akos015897771

    30. Ft-0659133

    31. P0492

    32. Q27286336

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 184.13 g/mol
    Molecular Formula C4H13N2O4P
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count0
    Exact Mass184.06129390 g/mol
    Monoisotopic Mass184.06129390 g/mol
    Topological Polar Surface Area102 Ų
    Heavy Atom Count11
    Formal Charge0
    Complexity76.3
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antinematodal Agents

    Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice. (See all compounds classified as Antinematodal Agents.)

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SCIENCES LIMITED","customerCountry":"INDIA","quantity":"31.95","actualQuantity":"31.95","unit":"KGS","unitRateFc":"370","totalValueFC":"11923.2","currency":"USD","unitRateINR":"31302","date":"02-Aug-2024","totalValueINR":"1000098.9","totalValueInUsd":"11923.2","indian_port":"Hyderabad Air","hs_no":"29335990","bill_no":"4846776","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ADD:ROOM 236, I-SHAPED NORTH BUILDING, NO 115 WENYI ROAD,HANGZHOU,ZHEJIANG PROVINCE,CHINA, 310012 China","customerAddress":"LUXOR PARKNO.NO.8-2-120\/86\/9\/B, OPP"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722623400,"product":"1-(CYCLOPROPYLMETHYL)PIPERAZINE","address":"PLOT NO. 193, HOUSE NO. 5-35\/50,","city":"HYDERABAD, AP","supplier":"MILVERPHARMA PVT LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"BIOPHORE INDIA PHARMACEUTICALS PVT 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LTD","supplierCountry":"CHINA","foreign_port":"BEIJING, 11","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"97.00","actualQuantity":"97","unit":"KGS","unitRateFc":"264.4","totalValueFC":"25870.6","currency":"USD","unitRateINR":"22371","date":"05-Aug-2024","totalValueINR":"2169990","totalValueInUsd":"25870.6","indian_port":"Dahez-SEZ","hs_no":"29329990","bill_no":"1003858","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING, 11","supplierAddress":"N\/A","customerAddress":"PLOT 170-172, CHANDRAMOULI,INDUSTR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723487400,"product":"INTERMEDIATES - 1-(CYCLOPROPYLCARBONYL)PIPERAZINE HYDROCHLORIDE","address":"SCO 915, 2ND FLOOR,","city":"CHANDIGARH.","supplier":"SHANDONG BOYUAN PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ADLEY LAB 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NO.12 TAIXING EAST STREETJIBEI ECONOMIC DEVELOPMENT ZONE,JIYANG DIST, JINAN CITY, 251400 , S SDNF","customerAddress":"SCO 915, 2ND FLOOR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723833000,"product":"1-PIPERAZINECARBOXYLIC ACID,2-(CYANOMETHYL)- 4-[5,6,7,8-TETRAHYDRO-2-[[(2S)-1-METHYL-2-PYRROLIDINYL]METHOXY]- 7-(PHENYLM","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"M\/S DFM INTERNATIONAL LIMITED.","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"0.80","actualQuantity":"0.8","unit":"KGS","unitRateFc":"12300","totalValueFC":"9954","currency":"USD","unitRateINR":"1043655","date":"17-Aug-2024","totalValueINR":"834924","totalValueInUsd":"9954","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"5101497","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"ADD: RM1902 EASEY COMM BLDG 253-261HENNESSY RD WANCHAI HONG KONG.CHINA CN","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723919400,"product":"1-N-BOC-PIPERAZINE-3-CARBOXYLIC ACID METHYL ESTER - CS-D0654 - 129799-08-2","address":"102\/12 KRISHNA GREENLAND PARK,KASA","city":"THANE,MAHARASHTRA","supplier":"SHANGHAI KAIXIN PHARMACEUTICALS CO.","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"JINAY PHARMACEUTICALS PRIVATE ","customerCountry":"INDIA","quantity":"0.55","actualQuantity":"550","unit":"GMS","unitRateFc":"0.7","totalValueFC":"389.5","currency":"USD","unitRateINR":"59.4","date":"18-Aug-2024","totalValueINR":"32668.93","totalValueInUsd":"389.5","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"5119465","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":",LTD ROOM 502,5\/F NO.2 BUILDING 720CAILUN RD ZHANGJIANG HIGH-TECH PARKSHANGHAI 201203 CHINA","customerAddress":"102\/12 KRISHNA GREENLAND PARK,KASA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724005800,"product":"1-((4\\'-CHLORO-5,5-DIMETHYL-3,4,5,6 TETRAHYDRO- [1,1\\'-BIPHENYL]-2 YL)METHYL )PIPERAZINE DIHYDROCHLORIDE","address":"H NO 15-31-1\/HIG-V-148, ,? Phase-V, KPHB Colony, ,? Kukatpally , ?HYDERABAD ,? TELANGANA,? 500085","city":"","supplier":"GTM CHINA CO., LTD.","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"DIVI PHARMA","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"1000","totalValueFC":"1011.6","currency":"USD","unitRateINR":"84850","date":"19-Aug-2024","totalValueINR":"84850","totalValueInUsd":"1011.6","indian_port":"Hyderabad Air","hs_no":"29189990","bill_no":"5135089","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"NO. 920th, West Tower, Manhattansquare, Xinbei District,Changzhou, Jiangsu Province CN","customerAddress":"H NO 15-31-1\/HIG-V-148, ,? Phase-V, KPHB Colony, ,? Kukatpally , ?HYDERABAD ,? TELANGANA,? 500085"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724092200,"product":"1-(3-HYDROXYMETHYL PYRIDIN-2-YL)-2-PHENYL-4-METHYL PIPERAZINE","address":"ACME PLAZA, ANDHERI KURLA ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"M\/S. ZHEJIANG LIAOYUAN PHARMACEUTICAL CO., LTD.","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"600.00","actualQuantity":"600","unit":"KGS","unitRateFc":"180","totalValueFC":"109250.8","currency":"USD","unitRateINR":"15273","date":"20-Aug-2024","totalValueINR":"9163800","totalValueInUsd":"109250.8","indian_port":"JNPT","hs_no":"29335990","bill_no":"5146157","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ZHEJIANG PROVINCIAL CHEMICAL AND MEDICAL RAW MATERIAL BASE LINHAI ZONE, DUQIAO TOWN, LINHAI CITY, 317016, China","customerAddress":"ACME PLAZA, ANDHERI KURLA ROAD,"}]
    04-Jan-2021
    20-Aug-2024
    KGS
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