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Piritramide

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ACTIVE PHARMA INGREDIENTS

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Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

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API REF. PRICE (USD/KG)

$ 0

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Chemistry

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Also known as: Dipidolor, Pirinitramide, Dipiritramide, Piridolan, 302-41-0, R 3365

Molecular Formula

C₂₇H₃₄N₄O

Molecular Weight

430.6 g/mol

InChI Key

IHEHEFLXQFOQJO-UHFFFAOYSA-N

FDA UNII

4RP92LYZ2F

A diphenylpropylamine with intense narcotic analgesic activity of long duration. It is a derivative of MEPERIDINE with similar activity and usage.

1 2D Structure

Piritramide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-(3-cyano-3,3-diphenylpropyl)-4-piperidin-1-ylpiperidine-4-carboxamide

2.1.2 InChI

InChI=1S/C27H34N4O/c28-22-26(23-10-4-1-5-11-23,24-12-6-2-7-13-24)14-19-30-20-15-27(16-21-30,25(29)32)31-17-8-3-9-18-31/h1-2,4-7,10-13H,3,8-9,14-21H2,(H2,29,32)

2.1.3 InChI Key

IHEHEFLXQFOQJO-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CCN(CC1)C2(CCN(CC2)CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)N

2.2 Other Identifiers

2.2.1 UNII

4RP92LYZ2F

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Dipidolor

2. Dipydolor

3. Pirinitramide

4. Piritramid

2.3.2 Depositor-Supplied Synonyms

1. Dipidolor

2. Pirinitramide

3. Dipiritramide

4. Piridolan

5. 302-41-0

6. R 3365

7. 2,2-diphenyl-4-(4-piperidino-4-carbamoylpiperidino)butyronitrile

8. 4rp92lyz2f

9. Ids-np-013

10. 1'-(3-cyano-3,3-diphenylpropyl)(1,4'-bipiperidine)-4'-carboxamide

11. Piritramide (inn)

12. (1,4'-bipiperidine)-4'-carboxamide, 1'-(3-cyano-3,3-diphenylpropyl)-

13. Piritramid

14. Piritramide [inn]

15. 1'-(3-cyano-3,3-diphenylpropyl)-(1,4'-bipiperidine)-4'-carboxamide

16. 1-(3-cyano-3,3-diphenylpropyl)-4-piperidin-1-ylpiperidine-4-carboxamide

17. R-3365

18. Piritramide [inn:ban:dcf]

19. Piritramida

20. Piritramidum

21. 1'-(3-cyano-3,3-diphenylpropyl)-[1,4'-bipiperidine]-4'-carboxamide

22. Piritramidum [inn-latin]

23. Piritramida [inn-spanish]

24. Einecs 206-124-3

25. Unii-4rp92lyz2f

26. Brn 0501362

27. Dea No. 9642

28. [1,4'-bipiperidine]-4'-carboxamide, 1'-(3-cyano-3,3-diphenylpropyl)-

29. Dipidolor (tn)

30. Piritramide [mi]

31. Piritramide [mart.]

32. Schembl26151

33. Piritramide [who-dd]

34. Chembl559288

35. Dtxsid00184293

36. Chebi:135699

37. Zinc538198

38. Db12492

39. D07288

40. Q416439

41. Isonipecotamide, 1-(3-cyano-3,3-diphenylpropyl)-4-piperidino-

42. 1-(3-cyano-3,3-diphenylpropyl)-4-(piperidin-1-yl)piperidine-4-carboximidic Acid

2.4 Create Date

2005-03-27

3 Chemical and Physical Properties

Molecular Formula	C₂₇H₃₄N₄O
Molecular Weight	430.6 g/mol
XLogP3	3.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	430.27326172 g/mol
Monoisotopic Mass	430.27326172 g/mol
Topological Polar Surface Area	73.4 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	638
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Narcotics

Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. (See all compounds classified as Narcotics.)

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)

4.2 ATC Code

N02AC03

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

N - Nervous system

N02 - Analgesics

N02A - Opioids

N02AC - Diphenylpropylamine derivatives

N02AC03 - Piritramide

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ABOUT THIS PAGE

Piritramide Manufacturers

A Piritramide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Piritramide, including repackagers and relabelers. The FDA regulates Piritramide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Piritramide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Piritramide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Piritramide Suppliers

A Piritramide supplier is an individual or a company that provides Piritramide active pharmaceutical ingredient (API) or Piritramide finished formulations upon request. The Piritramide suppliers may include Piritramide API manufacturers, exporters, distributors and traders.

click here to find a list of Piritramide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Piritramide GMP

Piritramide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Piritramide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Piritramide GMP manufacturer or Piritramide GMP API supplier for your needs.

Piritramide CoA

A Piritramide CoA (Certificate of Analysis) is a formal document that attests to Piritramide's compliance with Piritramide specifications and serves as a tool for batch-level quality control.

Piritramide CoA mostly includes findings from lab analyses of a specific batch. For each Piritramide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Piritramide may be tested according to a variety of international standards, such as European Pharmacopoeia (Piritramide EP), Piritramide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Piritramide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.