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ACTIVE PHARMA INGREDIENTS

8 API Suppliers, 6 USDMF, 1 EU WC, 5 NDC API, 4 Listed Suppliers

8 API Suppliers
6 USDMF
1 EU WC
5 NDC API
4 Listed Suppliers

DEVELOPMENTS

25 Drugs in Development

25 Drugs in Development

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

4 FDF Dossiers, 2 FDA Orange Book, 2 Canada

4 FDF Dossiers
2 FDA Orange Book
2 Canada

DIGITAL CONTENT

37 NEWS #PharmaBuzz

media
37 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

globalSalesInformation
1 US Medicaid Prescriptions

MARKET PLACE

6 APIs

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6 APIs

PATENTS & EXCLUSIVITIES

10 US Patents, 10 US Exclusivities

patents
10 US Patents
10 US Exclusivities

HRV Pitolisant Hydrochloride

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

1INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

25DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

65,551,787

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 903576-44-3, Ciproxidine, Bf 2649, Pitolisant hcl, Pitolisant (hydrochloride), Bf 2649 hydrochloride

Molecular Formula

C₁₇H₂₇Cl₂NO

Molecular Weight

332.3 g/mol

InChI Key

XLFKECRRMPOAQS-UHFFFAOYSA-N

FDA UNII

YV33CH63HI

1 2D Structure

Pitolisant Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine;hydrochloride

2.1.2 InChI

InChI=1S/C17H26ClNO.ClH/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19;/h7-10H,1-6,11-15H2;1H

2.1.3 InChI Key

XLFKECRRMPOAQS-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CCN(CC1)CCCOCCCC2=CC=C(C=C2)Cl.Cl

2.2 Other Identifiers

2.2.1 UNII

YV33CH63HI

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 903576-44-3

2. Ciproxidine

3. Bf 2649

4. Pitolisant Hcl

5. Pitolisant (hydrochloride)

6. Bf 2649 Hydrochloride

7. Yv33ch63hi

8. Pitolisant Hydrochloride [usan]

9. 1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine Hydrochloride

10. Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-, Hydrochloride

11. 903576-44-3 (hcl)

12. Wakix (tn)

13. Pitolisant Hydrochloride (usan)

14. 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine Hydrochloride

15. 1-{3-[3-(4-chlorophenyl)propoxy]propyl}piperidine Hydrochloride

16. Piperidine, 1-(3-(3-(4-chlorophenyl)propoxy)propyl)-, Hydrochloride

17. Bf 2.649

18. Unii-yv33ch63hi

19. Schembl4591893

20. Bf-2649 Hydrochloride

21. Chembl4164059

22. Dtxsid50238098

23. Pitolisant;ciproxidine; Bf2649

24. Amy23423

25. Bcp16427

26. Ex-a1420

27. Hy-12199b

28. Pitolisant Hydrochloride [mi]

29. S5926

30. Akos024457784

31. Cs-1501

32. Sb17036

33. Pitolisant Hydrochloride [who-dd]

34. Ac-36017

35. As-72196

36. A3727

37. Pitolisant Hydrochloride [orange Book]

38. C77058

39. D11490

40. A900088

41. Q27895485

42. 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine;hydrochloride

43. 1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine Monohydrochloride

44. Piperidine, 1-(3-(3-(4-chlorophenyl)propoxy)propyl)-, Hydrochloride (1:1)

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₁₇H₂₇Cl₂NO
Molecular Weight	332.3 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	8
Exact Mass	331.1469699 g/mol
Monoisotopic Mass	331.1469699 g/mol
Topological Polar Surface Area	12.5 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	235
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2