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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 5189-11-7, Pizotyline malate, Pizotifen (malate), Pizotifen hydrogen malate, Pizotifenmalate, 99o99yvr4c
Molecular Formula
C23H27NO5S
Molecular Weight
429.5  g/mol
InChI Key
IWAWCPZVTXCFKD-UHFFFAOYSA-N
FDA UNII
99O99YVR4C

Pizotifen Malate
1 2D Structure

Pizotifen Malate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-hydroxybutanedioic acid;1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine
2.1.2 InChI
InChI=1S/C19H21NS.C4H6O5/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18;5-2(4(8)9)1-3(6)7/h2-5,10,13H,6-9,11-12H2,1H3;2,5H,1H2,(H,6,7)(H,8,9)
2.1.3 InChI Key
IWAWCPZVTXCFKD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
99O99YVR4C
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 5189-11-7

2. Pizotyline Malate

3. Pizotifen (malate)

4. Pizotifen Hydrogen Malate

5. Pizotifenmalate

6. 99o99yvr4c

7. 4-(9,10-dihydro-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxysuccinate

8. 5189-11-7 (malate)

9. Chebi:50213

10. Sanomigran

11. Nsc-758899

12. Bc-105 (malate);pizotyline (malate)

13. Sanomtgran

14. Sandomigran (tn)

15. Piperidine, 4-(9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-, Malate (1:1)

16. Mosegor

17. Litec Malate

18. Sandomigran Malate

19. Sandomygran Malate

20. 4-(9,10-dihydro-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine Malate

21. Bc 105 Malate

22. Sr-05000001896

23. Einecs 225-970-4

24. Mosegor (tn)

25. Pizotyline (malate)

26. Bc-105 (malate)

27. Prestwick0_000992

28. Prestwick1_000992

29. Prestwick2_000992

30. Prestwick3_000992

31. Unii-99o99yvr4c

32. Bspbio_001083

33. Schembl365598

34. Spectrum1505003

35. Spbio_002974

36. Pizotyline Malate [mi]

37. Bpbio1_001193

38. Chembl1592663

39. Hy-b0115a

40. Dtxsid60966214

41. Pizotifen Malate [who-dd]

42. Hms1571g05

43. Hms2093g20

44. Hms2098g05

45. Hms3651c11

46. Hms3715g05

47. Hms3884m13

48. Pharmakon1600-01505003

49. Bcp21824

50. Mfcd01700978

51. Nsc758899

52. S1394

53. Akos015907762

54. Ccg-213329

55. Cs-1871

56. Nsc 758899

57. Ncgc00096062-01

58. Ncgc00096062-02

59. As-10171

60. Malic Acid, Compound With 4-(9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methylpiperidine (1:1)

61. Sw197333-4

62. C75436

63. D08397

64. Pizotyline Malate; Bc-105 Malate; Litec Malate

65. 189p117

66. Q-201591

67. Sr-05000001896-1

68. Sr-05000001896-3

69. Q27121986

70. 2-hydroxybutanedioic Acid--4-(9,10-dihydro-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine (1/1)

71. 2-hydroxybutanedioic Acid;1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine

72. 4-(9,10-dihydro-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxybutanedioate

73. Butanedioic Acid, Hydroxy-, Compd. With 4-(9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methylpiperidine (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 429.5 g/mol
Molecular Formula C23H27NO5S
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass429.16099414 g/mol
Monoisotopic Mass429.16099414 g/mol
Topological Polar Surface Area126 Ų
Heavy Atom Count30
Formal Charge0
Complexity535
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

API Reference Price

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30-Sep-2022
18-May-2024
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ABOUT THIS PAGE

Pizotifen Malate Manufacturers

A Pizotifen Malate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pizotifen Malate, including repackagers and relabelers. The FDA regulates Pizotifen Malate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pizotifen Malate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Pizotifen Malate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Pizotifen Malate Suppliers

A Pizotifen Malate supplier is an individual or a company that provides Pizotifen Malate active pharmaceutical ingredient (API) or Pizotifen Malate finished formulations upon request. The Pizotifen Malate suppliers may include Pizotifen Malate API manufacturers, exporters, distributors and traders.

click here to find a list of Pizotifen Malate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Pizotifen Malate GMP

Pizotifen Malate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pizotifen Malate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pizotifen Malate GMP manufacturer or Pizotifen Malate GMP API supplier for your needs.

Pizotifen Malate CoA

A Pizotifen Malate CoA (Certificate of Analysis) is a formal document that attests to Pizotifen Malate's compliance with Pizotifen Malate specifications and serves as a tool for batch-level quality control.

Pizotifen Malate CoA mostly includes findings from lab analyses of a specific batch. For each Pizotifen Malate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pizotifen Malate may be tested according to a variety of international standards, such as European Pharmacopoeia (Pizotifen Malate EP), Pizotifen Malate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pizotifen Malate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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