Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers, 3 KDMF, 3 Listed Suppliers

3 API Suppliers
3 KDMF
3 Listed Suppliers

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

MARKET PLACE

4 APIs

marketPlace
4 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 301692-76-2, Cg100649, 4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide, Cg-100649, Ij34d6ypao, Cg 100649

Molecular Formula

C₁₈H₁₆FNO₄S

Molecular Weight

361.4 g/mol

InChI Key

IJWPAFMIFNSIGD-UHFFFAOYSA-N

FDA UNII

IJ34D6YPAO

Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee.

1 2D Structure

Polmacoxib

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide

2.1.2 InChI

InChI=1S/C18H16FNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23)

2.1.3 InChI Key

IJWPAFMIFNSIGD-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC1(C(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC(=CC=C3)F)C

2.2 Other Identifiers

2.2.1 UNII

IJ34D6YPAO

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Cg100649

2.3.2 Depositor-Supplied Synonyms

1. 301692-76-2

2. Cg100649

3. 4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide

4. Cg-100649

5. Ij34d6ypao

6. Cg 100649

7. 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide

8. 4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)-benzenesulfonamide

9. 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxidanylidene-furan-2-yl]benzenesulfonamide

10. Benzenesulfonamide, 4-(3-(3-fluorophenyl)-4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl)-

11. Polmacoxib [usan:inn]

12. Unii-ij34d6ypao

13. Polmacoxib [usan]

14. Acelex (s. Korea)

15. Polmacoxibcg100649

16. Polmacoxib [inn]

17. Polmacoxib (usan/inn)

18. Polmacoxib [who-dd]

19. Chembl166863

20. Gtpl8316

21. Schembl3233093

22. Ex-a601

23. Dtxsid901029389

24. Zinc589683

25. Bcp15550

26. Bdbm50474760

27. Akos025149767

28. Db12399

29. Sb17177

30. Da-42861

31. Hy-16726

32. Cs-0012326

33. Ft-0700281

34. D10656

35. A857030

36. J-690277

37. Q19598695

38. Cg100649; Cg-100649; Cg 100649

39. 2-(4-tert-butylphenyl)-1h-benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]-1h-benzimidazole

40. 5-{4-(aminosulfonyl)phenyl}-2,2-dimethyl-4-(3-fluorophenyl)-3(2h)-furanone

41. 1427301-99-2

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₁₆FNO₄S
Molecular Weight	361.4 g/mol
XLogP3	2.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	361.07840733 g/mol
Monoisotopic Mass	361.07840733 g/mol
Topological Polar Surface Area	94.8 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	672
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1