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Chemistry

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Also known as: 26853-31-6, Popc, Palmitoyloleoylphosphatidylcholine, Pc(16:0/18:1(9z)), [(2r)-3-hexadecanoyloxy-2-[(z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate, 1-hexadecanoyl-2-(9z-octadecenoyl)-sn-glycero-3-phosphocholine
Molecular Formula
C42H82NO8P
Molecular Weight
760.1  g/mol
InChI Key
WTJKGGKOPKCXLL-VYOBOKEXSA-N
FDA UNII
TE895536Y5

POPC
PC(16:0/18:1(9Z)) is a metabolite found in or produced by Saccharomyces cerevisiae.
1 2D Structure

POPC

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
2.1.2 InChI
InChI=1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
2.1.3 InChI Key
WTJKGGKOPKCXLL-VYOBOKEXSA-N
2.1.4 Canonical SMILES
CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC
2.1.5 Isomeric SMILES
CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC
2.2 Other Identifiers
2.2.1 UNII
TE895536Y5
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-palmitoyl-2-oleoyl-lecithin

2. 1-palmitoyl-2-oleoyl-phosphatidylcholine

3. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine

4. 1-palmitoyl-2-oleoylphosphatidylcholine

5. 1-palmitoyl-2-oleoylphosphatidylcholine, (r)-(z)-isomer

6. 1-palmotoyl-2-oleoylglycero-3-phosphocholine

7. 1-popc

8. Alpha-phosphatidylcholine-beta-oleoyl-gamma-palmitoyl

9. Beta-oleoyl-gamma-palmitoyl-l-alpha-phosphatidylcholine

10. Palmitoyloleoylphosphatidylcholine

11. Popc Lipid

2.3.2 Depositor-Supplied Synonyms

1. 26853-31-6

2. Popc

3. Palmitoyloleoylphosphatidylcholine

4. Pc(16:0/18:1(9z))

5. [(2r)-3-hexadecanoyloxy-2-[(z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl Phosphate

6. 1-hexadecanoyl-2-(9z-octadecenoyl)-sn-glycero-3-phosphocholine

7. 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine

8. Gpcho(34:1)

9. Pc(16:0/18:1w9)

10. Phosphatidylcholine(16:0/18:1)

11. Te895536y5

12. 1-16:0-2-18:1-phosphatidylcholine

13. 1-palmitoyl-2-oleoyl-sn-glycero-3-pc

14. 16:0-18:1-pc

15. (r,z)-2-(oleoyloxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) Phosphate

16. (r)-(z)-(4-oxido-9-oxo-7-(palmitoylmethyl)-3,5,8-trioxa-4-phosphahexacos-17-enyl)trimethylammonium 4-oxide

17. 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine

18. 1-popc

19. Pc 34:1

20. (r,z)-2-(oleoyloxy)-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl Phosphate

21. [3-hexadecanoyloxy-2-[(e)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl Phosphate

22. (2r)-3-(hexadecanoyloxy)-2-{[(9z)-octadec-9-enoyl]oxy}propyl 2-(trimethylazaniumyl)ethyl Phosphate

23. 1-palmitoyl-2-oleoyl-lecithin

24. Unii-te895536y5

25. Ptd-cho

26. L-b-oleoyl-g-palmitoyl-a-lecithin

27. Einecs 248-056-7

28. 70778-75-5

29. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine

30. 1-palmitoyl-2-oleoyl-gpc

31. Schembl45162

32. Chebi:73001

33. Gpcho(16:0/18:1omega9)

34. Pc(16:0/18:1omega9)

35. Dtxsid101029642

36. Cmc_12041

37. Cmc_12042

38. Lmgp01010005

39. Mfcd00077387

40. 1-palmitoyl-2-oleoyl-l-alpha-lecithin

41. 2-oleoyl-1-palmitoylphosphatidylcholine

42. L-a-phosphatidylcholine (egg, Chicken)

43. 1-palmitoyl-2-oleoyl-phosphatidylcholine

44. Phosphatidylcholine(16:0/18:1omega9)

45. 1-palmitoyl-2-oleoyl-sn-3-phosphocholine

46. As-67722

47. Bp-26319

48. Bp-26332

49. Phosphatidylcholine (1-16:0-2-18:1)

50. Gpc(16:0/18:1)

51. Hy-130462

52. Cs-0108058

53. 1-palmitoyl-2-oleoyl-3-sn-phosphatidylcholine

54. 1-palmitoyl-2-oleoyl-gpc (16:0/18:1)

55. 1-palmitoyl-2-oleyl-3-sn-phosphatidylcholine

56. 1-palmitoyl-2-oleoyl-sn-glycero-phosphocholine

57. 16:0-18:1 Pc

58. 3-sn-phosphatidylcholine, 2-oleoyl-1-palmitoyl

59. L-alpha-1-palmitoyl-2-oleoylphosphatidylcholine

60. 1-palmitoyl-2-oleoyl-l-alpha-phosphatidylcholine

61. A905125

62. 1-hexadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine

63. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphorylcholine

64. 1-palmitoyl-2-oleoyl-sn-glycero-phosphatidylcholine

65. 1-palmitoyl-2-oleoyl-sn-glyceryl-3-phosphorylcholine

66. Beta-oleoyl-gamma-palmitoyl-l-alpha-phosphatidylcholine

67. Q10860475

68. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (popc)

69. 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphatidylcholine

70. Egg Pc, L-alpha-phosphatidylcholine (egg, Chicken), Powder

71. Brain Pc, L-alpha-phosphatidylcholine (brain, Porcine), Powder

72. 1-hexadecanoyl-2-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine

73. Brain Pc, L-alpha-phosphatidylcholine (brain, Porcine), Chloroform

74. 16:0-18:1 Pc, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Powder

75. (2r)-2-[(9z)-9-octadecenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl Phosphate

76. (r)-2-(oleoyloxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) Phosphate

77. (r,z)-2-(oleoyloxy)-3-(palmitoyloxy)propyl(2-(trimethylammonio)ethyl)phosphate

78. 16:0-18:1 Pc, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Chloroform

79. (2-{[(2r)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl Phosphonato]oxy}ethyl)trimethylazanium

80. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (main Component Of Egg Phosphatidylcholines / Epc, Cas 97281-44-2)

81. 3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium, 4-hydroxy-n,n,n-trimethyl-9-oxo-7-(((1-oxohexadecyl)oxy)methyl)-, Inner Salt, 4-oxide, (7r,17z)-

82. 3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium, 4-hydroxy-n,n,n-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, Inner Salt, 4-oxide, (7r,17z)- 3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium, 4-hydroxy

83. 3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium, 4-hydroxy-n,n,n-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, Inner Salt, 4-oxide, [r-(z)]-

84. Choline, Hydroxide, Dihydrogen Phosphate, Inner Salt, Ester With 1-palmito-2-olein, L- (8ci)

85. Ethanaminium, 2-[[hydroxy[[(2r)-3-[(1-oxohexadecyl)oxy]-2-[[(9z)-1-oxo-9-octadecenyl]oxy]propyl]oxy]phosphinyl]oxy]-n,n,n-trimethyl-, Inner Salt

2.4 Create Date
2005-06-08
3 Chemical and Physical Properties
Molecular Weight 760.1 g/mol
Molecular Formula C42H82NO8P
XLogP313.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count41
Exact Mass759.57780557 g/mol
Monoisotopic Mass759.57780557 g/mol
Topological Polar Surface Area111 Ų
Heavy Atom Count52
Formal Charge0
Complexity899
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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04-Mar-2022
30-Sep-2024
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POPC Manufacturers

A POPC manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of POPC, including repackagers and relabelers. The FDA regulates POPC manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. POPC API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

POPC Suppliers

A POPC supplier is an individual or a company that provides POPC active pharmaceutical ingredient (API) or POPC finished formulations upon request. The POPC suppliers may include POPC API manufacturers, exporters, distributors and traders.

click here to find a list of POPC suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

POPC USDMF

A POPC DMF (Drug Master File) is a document detailing the whole manufacturing process of POPC active pharmaceutical ingredient (API) in detail. Different forms of POPC DMFs exist exist since differing nations have different regulations, such as POPC USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A POPC DMF submitted to regulatory agencies in the US is known as a USDMF. POPC USDMF includes data on POPC's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The POPC USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of POPC suppliers with USDMF on PharmaCompass.

POPC GMP

POPC Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of POPC GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right POPC GMP manufacturer or POPC GMP API supplier for your needs.

POPC CoA

A POPC CoA (Certificate of Analysis) is a formal document that attests to POPC's compliance with POPC specifications and serves as a tool for batch-level quality control.

POPC CoA mostly includes findings from lab analyses of a specific batch. For each POPC CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

POPC may be tested according to a variety of international standards, such as European Pharmacopoeia (POPC EP), POPC JP (Japanese Pharmacopeia) and the US Pharmacopoeia (POPC USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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