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1. Popg
2. Popg, L-
3. Popg, R-
4. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol
5. 185435-28-3
6. F72017vpr7
7. L-alpha-1-palmitoyl-2-oleoylglycerophosphoglycerol
8. 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol
9. 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-rac-glycerol
10. 1-hexadecanoyl-2-(9z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol)
11. [(2r)-1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (z)-octadec-9-enoate
12. 9-octadecenoic Acid (9z)-, (1r)-1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-2-((1-oxohexadecyl)oxy)ethyl Ester
13. 9-octadecenoic Acid (z)-, 1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-2-((1-oxohexadecyl)oxy)ethyl Ester, (1r)-
14. Pg(16:0/18:1)
15. 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-rac-glycerol Sodium Salt
16. Unii-f72017vpr7
17. 1-hexadecanoyl-2-(9z-octadecenoyl)-sn-glycero-3-phospho-sn-glycerol
18. Chebi:34080
19. Palmitoyloleoyl-phosphatidylglycerol
20. Lmgp04010002
21. 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)
22. Db11331
23. 1-palmitoyl-2-oleoyl-phosphatidylglycerol
24. Hy-142991
25. Cs-0374728
26. 16:0-18:1 Pg
27. 490h053
28. Q27115796
29. L-.alpha.-1-palmitoyl-2-oleoylglycerophosphoglycerol
30. 1-o-(1-o-palmitoyl-2-o-oleoyl-l-glycero-3-phospho)glycerol
31. {1-hexadecanoyl-2-[(z)-octadec-9-enoyl]-sn-glycero-3-phospho}glycerol
32. (19r)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda(5)-phosphahexacosan-19-yl (9z)-octadec-9-enoate
33. 1-hexadecanoyl-2-[cis-9-octadecanoyl]-sn-glycero-3-[phospho-rac-(1-glycerol)] Ammonium Salt
34. 9-octadecenoic Acid (9z)-, 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl Ester
| Molecular Weight | 749.0 g/mol |
|---|---|
| Molecular Formula | C40H77O10P |
| XLogP3 | 12.3 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 41 |
| Exact Mass | 748.52543565 g/mol |
| Monoisotopic Mass | 748.52543565 g/mol |
| Topological Polar Surface Area | 149 Ų |
| Heavy Atom Count | 51 |
| Formal Charge | 0 |
| Complexity | 868 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin which was indicated for the prevention of respiratory distress syndrome in premature infants.
FDA Label
Palmitoyloleoyl-phosphatidylglycerol is a replacement surfactant which prevents alveolar collapse when administered intratracheally.
Palmitoyloleoyl-phosphatidylglycerol reduces interfacial tension at the air/water interfaces in the alveoli. This prevents the tension from pulling the alveolar membranes inwards which would collapse them and lead to respiratory distress.
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