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ACTIVE PHARMA INGREDIENTS

31 API Suppliers, 17 USDMF, 4 CEP/COS, 6 JDMF, 2 EU WC, 3 KDMF, 20 NDC API, 9 Listed Suppliers

31 API Suppliers
17 USDMF
4 CEP/COS
6 JDMF
2 EU WC
3 KDMF
20 NDC API
9 Listed Suppliers

DEVELOPMENTS

11 Drugs in Development

11 Drugs in Development

FINISHED DOSAGE FORMULATIONS

1344 FDF Dossiers, 609 FDA Orange Book, 337 Europe, 157 Canada, 2 Australia, 191 South Africa, 48 Listed Dossiers

1344 FDF Dossiers
609 FDA Orange Book
337 Europe
157 Canada
2 Australia
191 South Africa
48 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

INJECTABLE;INJECTION - 20MG/100ML;30MG/100ML;600MG/100ML;310MG/100ML, INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;30MG/100ML;600MG/100ML;310MG/100ML, CAPSULE, EXTENDED RELEASE;ORAL - 10MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, CAPSULE, EXTENDED RELEASE;ORAL - 8MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 10MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 20MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 8MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;450MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;224MG/100ML;450MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;450MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;450MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;225MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;225MG/100ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;225MG/100ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, SOLUTION;IRRIGATION - 0.154MG/ML;0.92MG/ML;0.184MG/ML;0.2MG/ML;0.38MG/ML;2.1MG/ML;7.14MG/ML;0.42MG/ML, TABLET, EXTENDED RELEASE;ORAL - 10MEQ, TABLET, EXTENDED RELEASE;ORAL - 8MEQ, SOLUTION;IRRIGATION - 20MG/100ML;30MG/100ML;600MG/100ML;310MG/100ML, INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;104MG/100ML;600MG/100ML;310MG/100ML, INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;179MG/100ML;600MG/100ML;310MG/100ML, INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;254MG/100ML;600MG/100ML;310MG/100ML, INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;328MG/100ML;600MG/100ML;310MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;900MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;224MG/100ML;900MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;900MG/100ML, INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;900MG/100ML, FOR SOLUTION;ORAL - 420GM/BOT;1.48GM/BOT;5.72GM/BOT;11.2GM/BOT, EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1440ML), EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1920ML), EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML ;105MG/100ML;3.5GM/100ML (2400ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML ;147MG/100ML;3.9GM/100ML (1026ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (1540ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2053ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2566ML), INJECTABLE;INJECTION - 1.49GM/100ML, INJECTABLE;INJECTION - 14.9MG/ML, INJECTABLE;INJECTION - 2.24GM/100ML, INJECTABLE;INJECTION - 2.98GM/100ML, INJECTABLE;INJECTION - 29.8MG/ML, INJECTABLE;INJECTION - 745MG/100ML, INJECTABLE;INJECTION - 3.68GM/1000ML;3.05GM/1000ML;0.314GM/1000ML ;3.09GM/1000ML;6.34GM/1000ML;0.187GM/1000ML (5000ML), INJECTABLE;INJECTION - N/A/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;6.95GM/1000ML;0.187GM/1000ML (5000ML), SOLUTION;IRRIGATION - 0.48MG/ML;0.3MG/ML;0.75MG/ML;3.9MG/ML;6.4MG/ML;1.7MG/ML, FOR SOLUTION;ORAL - 10MEQ, FOR SOLUTION;ORAL - 20MEQ, FOR SOLUTION;ORAL - 40MEQ, TABLET;ORAL - 0.225GM;0.188GM;1.479GM, INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML), INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML), INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML), INJECTABLE;INJECTION - 5.15GM/1000ML;20GM/1000ML;5.4GM/1000ML;2.03GM/1000ML;0.157GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML), INJECTABLE;INJECTION - 5.15GM/1000ML;N/A/1000ML;5.4GM/1000ML;2.03GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML), INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;2.03GM/1000ML;0.157GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML), INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;2.44GM/1000ML;0.314GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML), INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.157GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML), INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML), INJECTABLE;INJECTION - N/A/1000ML;N/A/1000ML;5.4GM/1000ML;2.44GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML), INJECTABLE;INJECTION - 2MEQ/ML

drugProductComposition
INJECTABLE;INJECTION - 20MG/100ML;30MG/100ML;600MG/100ML;310MG/100ML
INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;30MG/100ML;600MG/100ML;310MG/100ML
CAPSULE, EXTENDED RELEASE;ORAL - 10MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
CAPSULE, EXTENDED RELEASE;ORAL - 8MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 10MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 20MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 8MEQ **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;450MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;224MG/100ML;450MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;450MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;450MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;225MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;225MG/100ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;225MG/100ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
SOLUTION;IRRIGATION - 0.154MG/ML;0.92MG/ML;0.184MG/ML;0.2MG/ML;0.38MG/ML;2.1MG/ML;7.14MG/ML;0.42MG/ML
TABLET, EXTENDED RELEASE;ORAL - 10MEQ
TABLET, EXTENDED RELEASE;ORAL - 8MEQ
SOLUTION;IRRIGATION - 20MG/100ML;30MG/100ML;600MG/100ML;310MG/100ML
INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;104MG/100ML;600MG/100ML;310MG/100ML
INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;179MG/100ML;600MG/100ML;310MG/100ML
INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;254MG/100ML;600MG/100ML;310MG/100ML
INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;328MG/100ML;600MG/100ML;310MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;900MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;224MG/100ML;900MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;900MG/100ML
INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;900MG/100ML
FOR SOLUTION;ORAL - 420GM/BOT;1.48GM/BOT;5.72GM/BOT;11.2GM/BOT
EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1440ML)
EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1920ML)
EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML ;105MG/100ML;3.5GM/100ML (2400ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML ;147MG/100ML;3.9GM/100ML (1026ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (1540ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2053ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2566ML)
INJECTABLE;INJECTION - 1.49GM/100ML
INJECTABLE;INJECTION - 14.9MG/ML
INJECTABLE;INJECTION - 2.24GM/100ML
INJECTABLE;INJECTION - 2.98GM/100ML
INJECTABLE;INJECTION - 29.8MG/ML
INJECTABLE;INJECTION - 745MG/100ML
INJECTABLE;INJECTION - 3.68GM/1000ML;3.05GM/1000ML;0.314GM/1000ML ;3.09GM/1000ML;6.34GM/1000ML;0.187GM/1000ML (5000ML)
INJECTABLE;INJECTION - N/A/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;6.95GM/1000ML;0.187GM/1000ML (5000ML)
SOLUTION;IRRIGATION - 0.48MG/ML;0.3MG/ML;0.75MG/ML;3.9MG/ML;6.4MG/ML;1.7MG/ML
FOR SOLUTION;ORAL - 10MEQ
FOR SOLUTION;ORAL - 20MEQ
FOR SOLUTION;ORAL - 40MEQ
TABLET;ORAL - 0.225GM;0.188GM;1.479GM
INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML)
INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)
INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)
INJECTABLE;INJECTION - 5.15GM/1000ML;20GM/1000ML;5.4GM/1000ML;2.03GM/1000ML;0.157GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)
INJECTABLE;INJECTION - 5.15GM/1000ML;N/A/1000ML;5.4GM/1000ML;2.03GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)
INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;2.03GM/1000ML;0.157GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)
INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;2.44GM/1000ML;0.314GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)
INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.157GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML)
INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML)
INJECTABLE;INJECTION - N/A/1000ML;N/A/1000ML;5.4GM/1000ML;2.44GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)
INJECTABLE;INJECTION - 2MEQ/ML

RELATED EXCIPIENT COMPANIES

1 Minakem, 1 Evonik, 11 Rochem International Inc, 21 SPI Pharma, 2 Seqens, 13 DKSH, 2 Jai Radhe Sales, 2 Pharm-RX Chemical, 9 Faran Shimi Pharmaceutical, 8 Boai NKY Pharmaceuticals Ltd, 1 Chynops Pharma, 17 Gangwal Healthcare, 2 Kewpie Corporation, 10 Nanjing Well Pharmaceutical, 2 Pfanstiehl, 4 ACG Worldwide, 16 Actylis, 2 Aeon Procare, 2 Alcedo Pharmachem, 9 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 38 BASF, 1 Bioplus Life Sciences, 1 Clariant, 11 Corel Pharma Chem, 5 DFE Pharma, 2 Finar, 11 Gangwal Chemicals, 4 Ideal Cures Pvt Ltd, 4 Ingredion Pharma Solutions, 26 Kerry, 1 Kima Chemical, 3 Lonza Capsugel, 2 Lubrizol Life Science Health, 19 Microlex e.U, 1 NEWEDGE Overseas, 2 Nomisma Healthcare, 3 Novo Excipients, 4 Pharmatrans-Sanaq, 11 Pluviaendo, 4 Prachin Chemical, 1 Qualicaps, 33 Roquette, 5 Seppic, 6 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 2 Shijiazhuang Huaxu Pharmaceutical, 11 Sigachi Industries, 1 The Dow Chemical Company, 2 Ulanqab Kema New Material, 1 Valens Pharmachem, 4 Vasa Pharmachem, 3 Vertellus, 2 Zhejiang Huakang Pharmaceutical

relatedExcipients
1 Minakem
1 Evonik
11 Rochem International Inc
21 SPI Pharma
2 Seqens
13 DKSH
2 Jai Radhe Sales
2 Pharm-RX Chemical
9 Faran Shimi Pharmaceutical
8 Boai NKY Pharmaceuticals Ltd
1 Chynops Pharma
17 Gangwal Healthcare
2 Kewpie Corporation
10 Nanjing Well Pharmaceutical
2 Pfanstiehl
4 ACG Worldwide
16 Actylis
2 Aeon Procare
2 Alcedo Pharmachem
9 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
38 BASF
1 Bioplus Life Sciences
1 Clariant
11 Corel Pharma Chem
5 DFE Pharma
2 Finar
11 Gangwal Chemicals
4 Ideal Cures Pvt Ltd
4 Ingredion Pharma Solutions
26 Kerry
1 Kima Chemical
3 Lonza Capsugel
2 Lubrizol Life Science Health
19 Microlex e.U
1 NEWEDGE Overseas
2 Nomisma Healthcare
3 Novo Excipients
4 Pharmatrans-Sanaq
11 Pluviaendo
4 Prachin Chemical
1 Qualicaps
33 Roquette
5 Seppic
6 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
2 Shijiazhuang Huaxu Pharmaceutical
11 Sigachi Industries
1 The Dow Chemical Company
2 Ulanqab Kema New Material
1 Valens Pharmachem
4 Vasa Pharmachem
3 Vertellus
2 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

105 Fillers, Diluents & Binders, 49 Direct Compression, 41 Coating Systems & Additives, 38 Thickeners and Stabilizers, 38 Taste Masking, 35 Disintegrants & Superdisintegrants, 35 Topical, 31 Lubricants & Glidants, 31 Granulation, 29 Controlled & Modified Release, 27 Parenteral, 26 Solubilizers, 24 Chewable & Orodispersible Aids, 22 Film Formers & Plasticizers, 21 Co-Processed Excipients, 12 Emulsifying Agents, 8 Empty Capsules, 6 Surfactant & Foaming Agents, 5 API Stability Enhancers, 4 Rheology Modifiers, 3 Coloring Agents, 1 Soft Gelatin

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 92 NEWS #PharmaBuzz

media
2 DATA COMPILATION #PharmaFlow
92 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

6 US Medicaid Prescriptions, 338 Finished Drug Prices

globalSalesInformation
6 US Medicaid Prescriptions
338 Finished Drug Prices

MARKET PLACE

32 APIs, 14 FDF Dossiers, 1 Intermediates

marketPlace
32 APIs
14 FDF Dossiers
1 Intermediates

PATENTS & EXCLUSIVITIES

17 US Patents, 1 US Exclusivities

patents
17 US Patents
1 US Exclusivities

REF. STANDARDS & IMPURITIES

1 USP

otherSolutions
1 USP

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

1344

FDF Dossiers

609

FDA Orange Book

337

Europe

157

Canada

Australia

191

South Africa

Listed Dossiers

11DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

46,811,336

Annual Reports (USD Million)

Finished Drug Prices

359 RELATED EXCIPIENT COMPANIES

591EXCIPIENTS BY APPLICATIONS

Chemistry

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Click the button for full data set

Also known as: 7447-40-7, Sylvite, Klotrix, Enseal, Slow-k, Klor-con

Molecular Formula

ClK

Molecular Weight

74.55 g/mol

InChI Key

WCUXLLCKKVVCTQ-UHFFFAOYSA-M

FDA UNII

660YQ98I10

A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.

1 2D Structure

Potassium Chloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

potassium;chloride

2.1.2 InChI

InChI=1S/ClH.K/h1H;/q;+1/p-1

2.1.3 InChI Key

WCUXLLCKKVVCTQ-UHFFFAOYSA-M

2.1.4 Canonical SMILES

[Cl-].[K+]

2.2 Other Identifiers

2.2.1 UNII

660YQ98I10

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Chloride, Potassium

2. Slow-k

2.3.2 Depositor-Supplied Synonyms

1. 7447-40-7

2. Sylvite

3. Klotrix

4. Enseal

5. Slow-k

6. Klor-con

7. Muriate Of Potash

8. Neobakasal

9. Potassium Monochloride

10. Chlorvescent

11. Kalitabs

12. Kaochlor

13. Potavescent

14. Kloren

15. Pfiklor

16. Rekawan

17. Chloropotassuril

18. Kcl-retard Zyma

19. Klor-lyte

20. K-contin

21. Kay Ciel

22. Monopotassium Chloride

23. K-lease

24. Kaon Cl

25. Kaon-cl

26. Micro-k

27. Potassium Chloride (kcl)

28. Chloride Of Potash

29. K-lor

30. K-tab

31. Ten-k

32. Kay-em

33. Potassiumchloride

34. Kaliumchlorid

35. Micro-k Ls

36. Kali Muriaticum

37. Emplets Potassium Chloride

38. Kaon-cl 10

39. Potassium;chloride

40. Sylvite (kcl)

41. Kaon Cl-10

42. Micro-k 10

43. Kcl

44. Potassium Chloride Solution

45. Sylvine

46. K+10

47. Chloride (as Potassium)

48. Steropotassium

49. Acronitol

50. Kaliduron

51. Kaliglutol

52. Kalilente

53. Kaliolite

54. Miopotasio

55. Durekal

56. Durules

57. Kadalex

58. Kalcorid

59. Kaleorid

60. Kalinorm

61. Kalipor

62. Kalipoz

63. Keylyte

64. Klorvess

65. Mfcd00011360

66. Nsc-77368

67. Potasion

68. Potasol

69. Celeka

70. Enpott

71. 14336-88-0

72. Natural Sylvite

73. Kato

74. Kalium Duriles

75. Kalium Durules

76. Kalium-durettes

77. Rekawan Retard

78. Kalium Retard

79. Lento-kalium

80. Peter-kal

81. Kalitrans Retard

82. Potassium Muriate

83. Durules-k

84. Kalium-r

85. Kay-ciel

86. Repone K

87. Diffu-k

88. Kalinor-retard P

89. Kalium Sr

90. Lento-k

91. Super K

92. Ultra K Chlor

93. Ultra-k-chlor

94. Kcl Retard

95. Addi-k

96. Cena-k

97. Ins No.508

98. K-care

99. K-grad

100. K-norm

101. Span-k

102. Clor-k-zaf

103. Potassium Chloride,ar,99.5%

104. Micro-k Extentcaps

105. Plus Kalium Retard

106. Potassium Chloride, Acs Reagent

107. Infalyte

108. Kayciel

109. Apo-k

110. Chebi:32588

111. K Tab

112. K-dur

113. K-lyte Cl

114. K-sol

115. Kay-cee-l

116. Leo-k

117. Micro-kalium Retard

118. Rum-k

119. Ins-508

120. Nu-k

121. Slow-k Tablets

122. Kalinorm Depottab

123. Tripotassium Trichloride

124. 660yq98i10

125. K+8

126. K-sr

127. Chlorid Draselny [czech]

128. Super K (salt)

129. Kaon-cl Tabs

130. Kalium S.r.

131. Klor-con M20

132. Chlorid Draselny

133. Potassium Cl

134. E 508

135. E-508

136. Buffer Solution, Ph 2.00

137. Buffer Solution, Ph 9.00

138. Potassium Chloride [jan]

139. Potassium Chloride, Ultra Dry

140. Klor-con M10

141. Klor-con M15

142. Potassium Chloride (k3cl3)

143. Caswell No. 686

144. Epiklor

145. Kali Chloratum

146. Kali Chloridum

147. Potassium, Reference Standard Solution

148. Potassii Chloridum

149. Klotrix (tn)

150. Klor-con (tn)

151. Ccris 1962

152. Klor-con 10

153. K-10

154. Hsdb 1252

155. Kaon-cl (tn)

156. K-dur (tn)

157. Potassium Chloride 10meq In Plastic Container

158. Potassium Thallium Chloride (ktlcl)

159. [kcl]

160. Einecs 231-211-8

161. Nsc 77368

162. Epa Pesticide Chemical Code 013904

163. Kcl (tn)

164. Potassium Chloride In Plastic Container

165. Kalii Chloridum

166. Potassium Chloride [usp:jan]

167. Unii-660yq98i10

168. Potassium Chloride 30meq In Plastic Container

169. Potassium Chloride 40meq In Plastic Container

170. Potassium Chloride Salt

171. Potassium Chloride,(s)

172. Potassium (as Chloride)

173. Potassium Chloride 20meq In Plastic Container

174. Wln: Ka G

175. Ec 231-211-8

176. Buffer Solution, Ph 1.01

177. Potassium(i) Chloride

178. B1653 [langual]

179. Isa (ionic Strength Adjustment Solution: 1 M Kcl)

180. Kali Muriaticum [hpus]

181. Potassium Chloride, Food Grade

182. Potassium Chloride [ii]

183. Potassium Chloride [mi]

184. Chembl1200731

185. Dtxsid5021178

186. Potassium Chloride (fru Grade)

187. Potassium Chloride [fcc]

188. Potassium Chloride Solution, 1m

189. Buffer Concentrate, Ph 10.01

190. Potassium Chloride (jp17/usp)

191. Potassium Chloride [hsdb]

192. Potassium Chloride [inci]

193. Potassium Chloride Solution, 1 M

194. Potassium Chloride Solution, 20%

195. Potassium Chloride, Optical Grade

196. Potassium Chloride [vandf]

197. Potassium Chloride, Lr, >=99%

198. Potassium Chloride [mart.]

199. Amy37139

200. Cs-b1714

201. Hy-y0537

202. Nsc77368

203. Potassium Chloride [usp-rs]

204. Potassium Chloride [who-dd]

205. Potassium Chloride [who-ip]

206. Potassium Chloride, Acs, 99.5%

207. Str03715

208. Potassium Chloride - Drilling Grade

209. Potassium Chloride Solution, 3.3 M

210. Potassium Chloride, Ar, >=99.5%

211. Akos015902779

212. Akos024438069

213. Akos024457458

214. Potassium Chloride 3m Aqueous Solution

215. Potassium Chloride Solution, 0.01 M

216. Db00761

217. Kalii Chloridum [who-ip Latin]

218. Potassium Chloride [orange Book]

219. Potassium Chloride, 1m Aqueous Solution

220. Chloride (as Potassium) [vandf]

221. Potassium (as Chloride) [vandf]

222. Potassium Chloride [ep Monograph]

223. Potassium Chloride, Bioxtra, >=99.0%

224. Potassium Chloride, Bp, Ph. Eur. Grade

225. E508

226. Potassium Chloride [usp Monograph]

227. Tham-e Component Potassium Chloride

228. Potassium Chloride Biochemical Grade = 99%

229. B7289

230. Ft-0645107

231. P1757

232. Potassium Chloride, Acs Reagent, >=99.0%

233. Potassium Chloride, P.a., 99.0-100.5%

234. Halflytely Component Potassium Chloride

235. Potassium Chloride (technical Grade, Type A)

236. Potassium Chloride (technical Grade, Type B)

237. Potassium Chloride Component Of Tham-e

238. Potassium Chloride, 99.997% (metals Basis)

239. Tis-u-sol Component Potassium Chloride

240. D02060

241. Potassium Chloride, Bioultra, >=99.5% (at)

242. Potassium Chloride, Reagentplus(r), >=99.0%

243. Potassium Chloride Component Of Halflytely

244. Potassium Chloride Component Of Tis-u-sol

245. Potassium Chloride Solution, In H2o (saturated)

246. Potassium Chloride, 99.999% Trace Metals Basis

247. Potassium Chloride, Saj First Grade, >=99.0%

248. Potassium Chloride, Tested According To Ph.eur.

249. Potassium Chloride, Trace Metals Grade 99.99%

250. Potassium Chloride, >=99.99% Trace Metals Basis

251. Potassium Chloride, 0.85m, Conductivity Standard

252. Potassium Chloride, Acs Reagent, 99.0-100.5%

253. Potassium Chloride, Jis Special Grade, >=99.5%

254. Potassium Chloride, Spectroscopy Grade, Ultrapure

255. Potassium Chloride, Usp Special, 99.0-100.5%

256. Potassium Chloride, Vetec(tm) Reagent Grade, 99%

257. Q184630

258. Potassium Chloride, 0.005m, Conductivity Standard

259. Potassium Chloride, 0.007m, Conductivity Standard

260. Potassium Chloride, 0.010m, Conductivity Standard

261. Potassium Chloride, 0.0145m, Conductivity Standard

262. Potassium Chloride, 0.0375m, Conductivity Standard

263. Potassium Chloride, 0.0765m, Conductivity Standard

264. Potassium Chloride, 0.117m, Conductivity Standard

265. Potassium Chloride, 0.159m, Conductivity Standard

266. Potassium Chloride, 1m Aqueous Solution, Rnase Free

267. Potassium Chloride, Puriss. P.a., >=99.5% (at)

268. Potassium Chloride Solution, Bioultra, ~3 M In H2o

269. Potassium Chloride, 0.00017m, Conductivity Standard

270. Potassium Chloride, 0.00068m, Conductivity Standard

271. Potassium Chloride, For Molecular Biology, >=99.0%

272. Potassium Chloride, ~0.000027m, Conductivity Standard

273. Potassium Chloride, Meets Ep, Usp Testing Specifications

274. Isa (ionic Strength Adjustment Solution: 1 M Kcl), 1 M Kcl

275. Potassium Chloride Crystal Optic Disc, 13mm X 2mm, Unpolished

276. Potassium Chloride Crystal Optic Disc, 25mm X 5mm, Unpolished

277. Potassium Chloride Crystal Optic Disc, 32mm X 3mm, Unpolished

278. Potassium Chloride Solution, Standard, Solution (volumetric), 1.0 M

279. Potassium Chloride, Bioultra, For Molecular Biology, >=99.5% (at)

280. Potassium Standard For Aas, Ready-to-use, Traceable To Bam, In H2o

281. Potassium Chloride Crystal Optic Disc, 13mm X 1mm, Polished Both Sides

282. Potassium Chloride Crystal Optic Disc, 13mm X 2mm, Polished Both Sides

283. Potassium Chloride Crystal Optic Disc, 22mm X 4mm, Polished Both Sides

284. Potassium Chloride Crystal Optic Disc, 25mm X 2mm, Polished Both Sides

285. Potassium Chloride Crystal Optic Disc, 25mm X 4mm, Polished Both Sides

286. Potassium Chloride Crystal Optic Disc, 32mm X 3mm, Polished Both Sides

287. Potassium Chloride Crystal Optic Disc, 38mm X 6mm, Polished Both Sides

288. Potassium Chloride Crystal Optic Rectangle, 30mm X 15mm X 4mm, Unpolished

289. Potassium Chloride Crystal Optic Rectangle, 41mm X 23mm X 6mm, Unpolished

290. Potassium Chloride Solution, Bioultra, For Molecular Biology, ~1 M In H2o

291. Potassium Chloride, Anhydrous, Beads, -10 Mesh, 99.99% Trace Metals Basis

292. Potassium Chloride, Nist Srm 1655, Kcl (cr) For Solution Calorimetry

293. Potassium Chloride, United States Pharmacopeia (usp) Reference Standard

294. Potassium Chloride Crystal Optic Disc, 32mm X 3mm (drilled), Polished Both Sides

295. Potassium Chloride Crystal Optic Rectangle, 30mm X 15mm X 4mm, Polished Both Sides

296. Potassium Chloride Crystal Optic Rectangle, 38.5mm X 19.5mm X 4mm, Unpolished

297. Potassium Chloride Solution, 0.075 M, Sterile-filtered, Bioxtra, Suitable For Cell Culture

298. Potassium Chloride Solution, Conductance Standard A Acc. To Iso 7888, 0.1 M Kcl

299. Potassium Chloride Solution, Conductance Standard B Acc. To Iso 7888, 0.01 M Kcl

300. Potassium Chloride Solution, Conductance Standard C Acc. To Iso 7888, 0.001 M Kcl

301. Potassium Chloride Solution, Conductivity 11.67 Ms/cm At 20 C, Analytical Standard

302. Potassium Chloride, Anhydrous, Beads, -10 Mesh, 99.999% Trace Metals Basis

303. Potassium Chloride, Anhydrous, Free-flowing, Redi-dri(tm), Acs Reagent, >=99%

304. Potassium Chloride, Anhydrous, Free-flowing, Redi-dri(tm), Reagentplus(r), >=99%

305. Potassium Chloride, Pharmaceutical Secondary Standard; Certified Reference Material

306. Potassium Chloride, Puriss. P.a., Reag. Iso, Reag. Ph. Eur., 99.5-100.5%

307. Potassium Atomic Spectroscopy Standard Concentrate 1.00 G K, For 1 L Standard Solution, 1.00 G/l, Analytical Standard

308. Potassium Atomic Spectroscopy Standard Concentrate 10.00 G K, 10.00 G/l, For 1l Standard Solution, Analytical Standard

309. Potassium Chloride Crystal Optic Rectangle, 30mm X 15mm X 4mm, (drilled), Polished Both Sides

310. Potassium Chloride Crystal Optic Rectangle, 38.5mm X 19.5mm X 4mm, (drilled), Polished Both Sides

311. Potassium Chloride, Powder, Bioreagent, Suitable For Cell Culture, Suitable For Insect Cell Culture, >=99.0%

312. Potassium Chloride, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, Fcc, E508, 99-100.5% (at), <=0.0001% Al

313. Potassium Standard Solution, Suitable For Atomic Absorption Spectrometry, 1000 Ppm K+, 1 Mg/ml K+

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	ClK
Molecular Weight	74.55 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	73.9325592 g/mol
Monoisotopic Mass	73.9325592 g/mol
Topological Polar Surface Area	0 Å²
Heavy Atom Count	2
Formal Charge	0
Complexity	2
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 26
Drug Name	Klor-con
PubMed Health	Potassium Chloride (By mouth)
Drug Classes	Nutriceutical, Potassium Supplement
Drug Label	Klor-ConM20 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 1500 mg of microencapsulated potassium chloride, USP equivalent to 20 mEq of potassium in a tablet.Klor-ConM15 is an immediately dispersing ex...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	10meq; 8meq
Market Status	Prescription
Company	Upsher-smith Labs

2 of 26
Drug Name	Klor-con m10
Drug Label	Klor-Con M20 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 1500 mg of microencapsulated potassium chloride, USP equivalent to 20 mEq of potassium in a tablet.Klor-Con M15 is an immediately dispers...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	10meq
Market Status	Prescription
Company	Upsher Smith Labs

3 of 26
Drug Name	Klor-con m15
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	15meq
Market Status	Prescription
Company	Upsher Smith Labs

4 of 26
Drug Name	Klor-con m20
Drug Label	Micro-K Extencaps Capsules and Micro-K 10 Extencaps Capsules are oral dosage forms of microencapsulated potassium chloride containing 600 and 750 mg, respectively, of potassium chloride, USP, equivalent to 8 and 10 mEq of potassium, respectiv...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	20meq
Market Status	Prescription
Company	Upsher Smith Labs

5 of 26
Drug Name	K-tab
PubMed Health	Potassium Chloride (By mouth)
Drug Classes	Nutriceutical, Potassium Supplement
Drug Label	K-TAB (potassium chloride extended-release tablets) is a solid oral dosage form of potassium chloride containing 750 mg of potassium chloride, USP, equivalent to 10 mEq of potassium in a film-coated (not enteric-coated), wax matrix tablet. This formu...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	20meq; 10meq
Market Status	Prescription
Company	Abbvie

6 of 26
Drug Name	Micro-k
Drug Label	Micro-K Extencaps Capsules and Micro-K 10 Extencaps Capsules are oral dosage forms of microencapsulated potassium chloride containing 600 and 750 mg, respectively, of potassium chloride, USP, equivalent to 8 and 10 mEq of potassium, respectiv...
Active Ingredient	Potassium chloride
Dosage Form	Capsule, extended release
Route	Oral
Strength	8meq
Market Status	Prescription
Company	Nesher Pharms

7 of 26
Drug Name	Micro-k 10
Drug Label	Potassium Chloride for Injection Concentrate, USP, is a sterile, nonpyrogenic, concentrated solution of potassium chloride, USP in water for injection administered by intravenous infusion only after dilution in a larger volume of fluid. They are prov...
Active Ingredient	Potassium chloride
Dosage Form	Capsule, extended release
Route	Oral
Strength	10meq
Market Status	Prescription
Company	Nesher Pharms

8 of 26
Drug Name	Potassium chloride
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release; Tablet; Injectable; Capsule, extended release
Route	oral; Injection; Oral
Strength	10.0meq; 20meq; 3meq/ml; 8.0meq; 10meq; 8meq; 2meq/ml
Market Status	Tentative Approval; Prescription
Company	Mylan Pharms; Anchen Pharms; Amneal Pharms; Hospira; Actavis Labs Fl; Eurand; Baxter Hlthcare; Paddock; Fresenius Kabi Usa; B Braun; Esi Lederle; Elan Pharm

9 of 26
Drug Name	Potassium chloride 10meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	14.9mg/ml; 746mg/100ml; 745mg/100ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

10 of 26
Drug Name	Potassium chloride 20meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	1.49gm/100ml; 29.8mg/ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

11 of 26
Drug Name	Potassium chloride 30meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	2.24gm/100ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

12 of 26
Drug Name	Potassium chloride 40meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	2.98gm/100ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

13 of 26
Drug Name	Potassium chloride in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	2meq/ml
Market Status	Prescription
Company	Fresenius Kabi Usa

14 of 26
Drug Name	Klor-con
PubMed Health	Potassium Chloride (By mouth)
Drug Classes	Nutriceutical, Potassium Supplement
Drug Label	Klor-ConM20 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 1500 mg of microencapsulated potassium chloride, USP equivalent to 20 mEq of potassium in a tablet.Klor-ConM15 is an immediately dispersing ex...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	10meq; 8meq
Market Status	Prescription
Company	Upsher-smith Labs

15 of 26
Drug Name	Klor-con m10
Drug Label	Klor-Con M20 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 1500 mg of microencapsulated potassium chloride, USP equivalent to 20 mEq of potassium in a tablet.Klor-Con M15 is an immediately dispers...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	10meq
Market Status	Prescription
Company	Upsher Smith Labs

16 of 26
Drug Name	Klor-con m15
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	15meq
Market Status	Prescription
Company	Upsher Smith Labs

17 of 26
Drug Name	Klor-con m20
Drug Label	Micro-K Extencaps Capsules and Micro-K 10 Extencaps Capsules are oral dosage forms of microencapsulated potassium chloride containing 600 and 750 mg, respectively, of potassium chloride, USP, equivalent to 8 and 10 mEq of potassium, respectiv...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	20meq
Market Status	Prescription
Company	Upsher Smith Labs

18 of 26
Drug Name	K-tab
PubMed Health	Potassium Chloride (By mouth)
Drug Classes	Nutriceutical, Potassium Supplement
Drug Label	K-TAB (potassium chloride extended-release tablets) is a solid oral dosage form of potassium chloride containing 750 mg of potassium chloride, USP, equivalent to 10 mEq of potassium in a film-coated (not enteric-coated), wax matrix tablet. This formu...
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release
Route	Oral
Strength	20meq; 10meq
Market Status	Prescription
Company	Abbvie

19 of 26
Drug Name	Micro-k
Drug Label	Micro-K Extencaps Capsules and Micro-K 10 Extencaps Capsules are oral dosage forms of microencapsulated potassium chloride containing 600 and 750 mg, respectively, of potassium chloride, USP, equivalent to 8 and 10 mEq of potassium, respectiv...
Active Ingredient	Potassium chloride
Dosage Form	Capsule, extended release
Route	Oral
Strength	8meq
Market Status	Prescription
Company	Nesher Pharms

20 of 26
Drug Name	Micro-k 10
Drug Label	Potassium Chloride for Injection Concentrate, USP, is a sterile, nonpyrogenic, concentrated solution of potassium chloride, USP in water for injection administered by intravenous infusion only after dilution in a larger volume of fluid. They are prov...
Active Ingredient	Potassium chloride
Dosage Form	Capsule, extended release
Route	Oral
Strength	10meq
Market Status	Prescription
Company	Nesher Pharms

21 of 26
Drug Name	Potassium chloride
Active Ingredient	Potassium chloride
Dosage Form	Tablet, extended release; Tablet; Injectable; Capsule, extended release
Route	oral; Injection; Oral
Strength	10.0meq; 20meq; 3meq/ml; 8.0meq; 10meq; 8meq; 2meq/ml
Market Status	Tentative Approval; Prescription
Company	Mylan Pharms; Anchen Pharms; Amneal Pharms; Hospira; Actavis Labs Fl; Eurand; Baxter Hlthcare; Paddock; Fresenius Kabi Usa; B Braun; Esi Lederle; Elan Pharm

22 of 26
Drug Name	Potassium chloride 10meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	14.9mg/ml; 746mg/100ml; 745mg/100ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

23 of 26
Drug Name	Potassium chloride 20meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	1.49gm/100ml; 29.8mg/ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

24 of 26
Drug Name	Potassium chloride 30meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	2.24gm/100ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

25 of 26
Drug Name	Potassium chloride 40meq in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	2.98gm/100ml
Market Status	Prescription
Company	Hospira; Baxter Hlthcare

26 of 26
Drug Name	Potassium chloride in plastic container
Active Ingredient	Potassium chloride
Dosage Form	Injectable
Route	Injection
Strength	2meq/ml
Market Status	Prescription
Company	Fresenius Kabi Usa

4.2 Therapeutic Uses

The oral dose of 10% potassium chloride elixir (Kay Ciel) required to reverse thiazide-induced hypokalemia was determined in 15 patients with essential hypertension who were taking Esidrix (hydrochlorothiazide) in a dose of 50 mg. twice daily. Each patient had maintained a serum potassium concentration of at least 0.5 meq./l. less than duplicate control values (mean decreases, 0.62 meq./l.) for at least 2 months during therapy with hydrochlorothiazide, 50 mg. twice daily. Potassium chloride 10% elixir was administered in a total daily dose of 40 mg. with bimonthly increments to 60 mg., 80 mg. and 100 mg. while the thiazide administration was maintained. The serum potassium deficit was repleted to 75% in 12 of the 15 patients. In 8 of the 12, this was accomplished with 40 mg. potassium chloride daily, and in 4, with 60 mg. daily. The latter dose is recommended in patients with thiazide-induced hypokalemia.

Schwartz AB and Swartz CD; J. Am. Med. Assoc.; VOL 230 P702-704 (1974)

Thirty-six adult patients with cardiovascular disorders were enrolled in an open 12 week study to evaluate the efficacy, safety and patient acceptance of sustained-release potassium chloride (Klotrix; I) tablets, at a dosage of 1.8 g daily. These patients were on an established regimen of potassium wasting diuretics as part of their treatment for hypertension or arteriosclerotic heart disease, and all were receiving an oral potassium supplement. On the first day of the study, the previously used oral potassium supplement was discontinued and I substituted. Serum potassium levels remained normal and other laboratory parameters did not change significantly as a result of the changeover from the previous potassium supplement to I. However, side effects occurred less frequently with I, and while more than half the patients commented on the bad taste or bad aftertaste of their previous supplement, no such comments were recorded for I. Patient acceptance of I was high, and 87% of the patients who completed the study expressed a preference for I over their previous oral potassium supplement.

Tarpley EL and Cordano A; Curr Ther Res Clin Exp.; VOL 21 ISS P282-288 (1977).

Medication (vet): as oral or parenteral source of potassium... in cattle it has been successfully used iv for "creeper cows"...& in cases of debilitating diarrhea. 1% Level in feed reduces incidence of urolithiasis in lambs, & orally...for...feeder calves...as electrolyle source.

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 472

Potassium chloride is of value for the relief of symptoms of hypokaliemic periodic paralysis, and the symptoms of Meniere's disease. Daily intake of potassium decreases the risk of stroke-associated mortality.

OECD; Screening Information Data Set (SIDS) Initial Assessment Report for SIDS Initial Assessment Meeting (SIAM) 13, Potassium Chloride (CAS 7447-40-7) (November 2001). Available from, as of March 23, 2015. https://www.inchem.org/pages/sids.html

For more Therapeutic Uses (Complete) data for POTASSIUM CHLORIDE (16 total), please visit the HSDB record page.

4.3 Drug Warning

The cardiac effects of hyperkalemia are principal toxic effects of potassium. They are mediated through changes in the intra/extracellular potassium ratio, which alters cardiac conduction. With no underlying conduction defects a transient increase in cardiac conduction occurs with potassium concentrations above 7 mmol/L, but a profound depression occurs when concentrations rise over 8.0 mmol/L. One of the effects of hyperkalemia is the depolarisation of cardiac muscle, which interferes with normal contractility. Potassium chloride exerts a direct irritant effect on the gastrointestinal mucosa.

International Programme on Chemical Safety (IPCS); Poisons Information Monograph: Potassium Chloride (PIM 430) (1992) Available from, as of November 15, 2006: https://www.inchem.org/documents/pims/pharm/potasscl.htm

Local pain and inflammation may result from subcutaneous injection). Skin rash has rarely been reported with potassium preparations.

The initial signs of poisoning are generally gastrointestinal: nausea, vomiting and diarrhea. These symptoms can develop into abdominal pain and eventually paralytic ileus. Gastrointestinal perforation after oral exposure can occur. Bleeding and perforation have been reported in patients receiving solid forms of potassium chloride.

A number of neuromuscular effects can be seen, usually with potassium concentrations of 7.0 mmol/L or higher. General weakness and flaccidity precede ascending paralysis. Tremor, paresthesias, decreased vibration perception and proprioception can be seen, but the sensory function is usually intact. Dysarthria and dysphagia may occur.

For more Drug Warnings (Complete) data for POTASSIUM CHLORIDE (8 total), please visit the HSDB record page.

4.4 Minimum/Potential Fatal Human Dose

3. 3= Moderately toxic: probably oral lethal dose (human) 0.5-5 g/kg, between 1 oz and 1 pint (or 1 lb) for 70 kg person (150 lb).

Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-124

4.5 Drug Indication

For use as an electrolyte replenisher and in the treatment of hypokalemia.

FDA Label

5 Pharmacology and Biochemistry

5.1 Pharmacology

The potassium ion is in the principle intracellular cation of most body tissues. Potassium ions participate in a number of essential physiological processes including the maintenance of intracellular tonicity, the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, and the maintenance of normal renal function. The intracellular concentration of potassium is approximately 150 to 160 mEq per liter. The normal adult plasma concentration is 3.5 to 5 mEq per liter. An active ion transport system maintains this gradient across the plasma membrane. Potassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. The usual dietary intake of potassium is 50 to 100 mEq per day. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake. Such depletion usually develops as a consequence of therapy with diuretics, primarily or secondary hyperaldosteronism, diabetic ketoacidosis, or inadequate replacement of potassium in patients on prolonged parenteral nutrition. Depletion can develop rapidly with severe diarrhea, especially if associated with vomiting. Potassium depletion due to these causes is usually accompanied by concomitant loss of chloride and is manifested by hypokalemia and metabolic alkalosis. Potassium depletion may produce weakness, fatigue, disturbances of cardiac rhythm (primarily ectopic beats), prominent U-waves in the electrocardiogram, and, in advanced cases, flaccid paralysis and/or impaired ability to concentrate urine. If potassium depletion associated with metabolic alkalosis cannot be managed by correcting the fundamental cause of the deficiency, e.g., where the patient requires long-term diuretic therapy, supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels. In rare circumstances (e.g., patients with renal tubular acidosis) potassium depletion may be associated with metabolic acidosis and hyperchloremia. In such patients, potassium replacement should be accomplished with potassium salts other than the chloride, such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate.

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Osmotic Laxative [EPC]; Potassium Compounds [CS]; Potassium Salt [EPC]; Increased Large Intestinal Motility [PE]

5.3 ATC Code

A - Alimentary tract and metabolism

A12 - Mineral supplements

A12B - Potassium

A12BA - Potassium

A12BA01 - Potassium chloride

B - Blood and blood forming organs

B05 - Blood substitutes and perfusion solutions

B05X - I.v. solution additives

B05XA - Electrolyte solutions

B05XA01 - Potassium chloride

5.4 Absorption, Distribution and Excretion

Absorption

Potassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine.

Route of Elimination

Potassium is a normal dietary constituent and, under steady-state conditions, the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake.

At steady state continuous excretion of potassium chloride in the urine and faeces equals the daily intake.

Orally and intravenously administered potassium chloride reaches an equilibrium between the extracellular fluid and intracellular space.

Almost all orally administered potassium chloride is absorbed. The peak level and its occurrence time after ingestion depend on the preparation administered.

About 90% of the ingested dose of potassium is absorbed by passive diffusion in the membrane of the upper intestine. Potassium is distributed to all tissues where it is the principal intracellular cation. Insulin, acid-base status, aldosterone, and adrenergic activity regulate cellular uptake of potassium. /potassium/

For more Absorption, Distribution and Excretion (Complete) data for POTASSIUM CHLORIDE (8 total), please visit the HSDB record page.

5.5 Mechanism of Action

Supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels.

K+ is the principal cation mediating the osmotic balance of the body fluids. In animals, the maintenance of normal cell volume and pressure depends on Na+ and K+ pumping. The K+/Na+ separation has allowed for evolution of reversible transmembrane electrical potentials essential for nerve and muscle action in animals, and both potassium and chloride are important in transmission of nerve impulses to the muscle fibers. /postasium/

OECD; Screening INformation Data Set (SIDS) Initial Assessment Report for SIDS Initial Assessment Meeting (SIAM) 13, Potassium Chloride (CAS 7447-40-7) (November 2001). Available from, as of March 23, 2015. https://www.inchem.org/pages/sids.html

The reported mutagenic effect of KCl most probably results from a disruption of osmotic balance of cells with a subsequent interference with chromosomal stability. This may result in the clastogenic effects (DNA breakage and chromosome structural instability) due to K+ effects on sequestering of Mg2+ ions required for normal maintenance of chromatin integrity. Other chemicals may also exert such effect (e.g. NaCl, sucrose).

Potassium and chloride is also important in the regulation of the acid-base balance of the body. Potassium is the principal base in tissues of blood cells, and Cl maintains electrochemical neutrality by anion exchange with bicarbonate (the chloride shift) in the CO2 transport in the blood red cells.

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USFDA APPLICATION NUMBER - 16682

DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5G...DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;30MG/100ML;600MG/100ML;310MG/100ML

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USFDA APPLICATION NUMBER - 18279

DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;450MG/100ML

USFDA APPLICATION NUMBER - 18362

DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;224...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;224MG/100ML;450MG/100ML

USFDA APPLICATION NUMBER - 18362

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USFDA APPLICATION NUMBER - 18362

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USFDA APPLICATION NUMBER - 19123

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USFDA APPLICATION NUMBER - 19691

DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;900MG/100ML

USFDA APPLICATION NUMBER - 19691

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DOSAGE - EMULSION;INTRAVENOUS - 3.3%;29MG/100...DOSAGE - EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2053ML)

USFDA APPLICATION NUMBER - 200656

DOSAGE - EMULSION;INTRAVENOUS - 3.3%;29MG/100...DOSAGE - EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2566ML)

USFDA APPLICATION NUMBER - 200656

DOSAGE - INJECTABLE;INJECTION - 1.49GM/100ML

USFDA APPLICATION NUMBER - 20161

DOSAGE - INJECTABLE;INJECTION - 14.9MG/ML

USFDA APPLICATION NUMBER - 20161

DOSAGE - INJECTABLE;INJECTION - 2.24GM/100ML

USFDA APPLICATION NUMBER - 20161

DOSAGE - INJECTABLE;INJECTION - 2.98GM/100ML

USFDA APPLICATION NUMBER - 20161

DOSAGE - INJECTABLE;INJECTION - 29.8MG/ML

USFDA APPLICATION NUMBER - 20161

DOSAGE - INJECTABLE;INJECTION - 745MG/100ML

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DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML;3.05GM/1000ML;0.314GM/1000ML ;3.09GM/1000ML;6.34GM/1000ML;0.187GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 207026

DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;3....DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;6.95GM/1000ML;0.187GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 207026

DOSAGE - SOLUTION;IRRIGATION - 0.48MG/ML;0.3M...DOSAGE - SOLUTION;IRRIGATION - 0.48MG/ML;0.3MG/ML;0.75MG/ML;3.9MG/ML;6.4MG/ML;1.7MG/ML

USFDA APPLICATION NUMBER - 20742

DOSAGE - FOR SOLUTION;ORAL - 10MEQ

USFDA APPLICATION NUMBER - 208019

DOSAGE - FOR SOLUTION;ORAL - 20MEQ

USFDA APPLICATION NUMBER - 208019

DOSAGE - FOR SOLUTION;ORAL - 40MEQ

USFDA APPLICATION NUMBER - 208019

DOSAGE - TABLET;ORAL - 0.225GM;0.188GM;1.479G...DOSAGE - TABLET;ORAL - 0.225GM;0.188GM;1.479GM

USFDA APPLICATION NUMBER - 213135

DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML)