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Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS Certifications

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Chemistry

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Also known as: 52549-17-4, Niflan, Pyranoprofen, 2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoic acid, Elicapric, Y-8004
Molecular Formula
C15H13NO3
Molecular Weight
255.27  g/mol
InChI Key
TVQZAMVBTVNYLA-UHFFFAOYSA-N
FDA UNII
2R7O1ET613

Pranoprofen
1 2D Structure

Pranoprofen

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
2.1.2 InChI
InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18)
2.1.3 InChI Key
TVQZAMVBTVNYLA-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
2R7O1ET613
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(5h-(1)benzopyrano(2,3-b)pyridin-7-yl)propionic Acid

2. Alpha-methyl-5h-(1)benzopyrano(2,3-b)pyridine-7-acetic Acid

3. Niflan

4. Nifran

5. Oftalar

6. Pyranoprofen

7. Pyranoprofen, Methyl-14c-labeled

8. Zaltoprofen

2.3.2 Depositor-Supplied Synonyms

1. 52549-17-4

2. Niflan

3. Pyranoprofen

4. 2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoic Acid

5. Elicapric

6. Y-8004

7. Nsc-759832

8. 2-{5h-chromeno[2,3-b]pyridin-7-yl}propanoic Acid

9. 2-(5h-(1)benzopyrano(2,3-b)pyridin-7-yl)propionic Acid

10. Chembl367463

11. 2r7o1et613

12. 2-(5h-[1]benzopyrano[2,3-b]pyridin-7-yl)propionic Acid

13. Ncgc00167980-01

14. Dsstox_cid_3497

15. Dsstox_rid_77055

16. Dsstox_gsid_23497

17. Pranoprofene

18. Pranoprofeno

19. Pranoprofenum

20. Pranoprofen [inn:jan]

21. Pranoprofene [inn-french]

22. Pranoprofenum [inn-latin]

23. Pranoprofeno [inn-spanish]

24. Cas-52549-17-4

25. Sr-05000001513

26. Brn 0889798

27. Pransus

28. Unii-2r7o1et613

29. Pranoprofen;

30. Elicapric (tn)

31. 2-(5h-(1)benzopyrano(2,3-b)pyridin-7yl)propionic Acid

32. Alpha-methyl-5h-(1)-benzopyrano(2,3-b)pyridine-7-acetic Acid

33. Alpha-methyl-5h-(1)benzopyrano(2,3-b)pyridine-7-acetic Acid

34. Pranoprofen [mi]

35. Pranoprofen [inn]

36. Pranoprofen [jan]

37. Pranoprofen (jp17/inn)

38. Pranoprofen [mart.]

39. Schembl26008

40. Pranoprofen [who-dd]

41. Dtxsid1023497

42. Chebi:32040

43. Pranoprofen, >=98% (hplc)

44. (2s)-2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoic Acid

45. Hms2090j03

46. Hms3651g06

47. Hms3714i03

48. Hms3884o16

49. Pharmakon1600-01502324

50. 5h-(1)benzopyrano(2,3,-b)pyridine-7-acetic Acid, Alpha-methyl-

51. Bcp11947

52. Ex-a5741

53. Hy-b0336

54. Tox21_112601

55. 5h-[1]benzopyrano[2,3-b]pyridine-7-acetic Acid, .alpha.-methyl-

56. Ac-697

57. Bdbm50286819

58. Mfcd00866111

59. Nsc759832

60. S1960

61. Akos015918442

62. Tox21_112601_1

63. Ccg-213822

64. Db13514

65. Nsc 759832

66. Ncgc00167980-02

67. As-12631

68. Ft-0652901

69. P2778

70. Sw199147-2

71. D01578

72. F17350

73. Ab01275517-01

74. Ab01275517_02

75. Ab01275517_03

76. 2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoicacid

77. 549p174

78. Q-201611

79. Q7238394

80. Sr-05000001513-1

81. Sr-05000001513-2

82. Brd-a64610707-001-01-0

83. I2-(10h-9-oxa-1-aza-anthracen-6-yl)-propionic Acid

84. 2-(5h-[1]benzopyrano-[2,3-b]pyridin-7-yl)propionic Acid

85. .alpha.-methyl-5h-(1)benzopyrano(2,3-b)pyridine-7-acetic Acid

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 255.27 g/mol
Molecular Formula C15H13NO3
XLogP32.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass255.08954328 g/mol
Monoisotopic Mass255.08954328 g/mol
Topological Polar Surface Area59.4 Ų
Heavy Atom Count19
Formal Charge0
Complexity346
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Gout Suppressants

Agents that increase uric acid excretion by the kidney (URICOSURIC AGENTS), decrease uric acid production (antihyperuricemics), or alleviate the pain and inflammation of acute attacks of gout. (See all compounds classified as Gout Suppressants.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


4.2 ATC Code

S01BC09

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


S - Sensory organs

S01 - Ophthalmologicals

S01B - Antiinflammatory agents

S01BC - Antiinflammatory agents, non-steroids

S01BC09 - Pranoprofen


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ABOUT THIS PAGE

Pranoprofen Manufacturers

A Pranoprofen manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pranoprofen, including repackagers and relabelers. The FDA regulates Pranoprofen manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pranoprofen API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Pranoprofen manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Pranoprofen Suppliers

A Pranoprofen supplier is an individual or a company that provides Pranoprofen active pharmaceutical ingredient (API) or Pranoprofen finished formulations upon request. The Pranoprofen suppliers may include Pranoprofen API manufacturers, exporters, distributors and traders.

click here to find a list of Pranoprofen suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Pranoprofen JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Pranoprofen Drug Master File in Japan (Pranoprofen JDMF) empowers Pranoprofen API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Pranoprofen JDMF during the approval evaluation for pharmaceutical products. At the time of Pranoprofen JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Pranoprofen suppliers with JDMF on PharmaCompass.

Pranoprofen GMP

Pranoprofen Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pranoprofen GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pranoprofen GMP manufacturer or Pranoprofen GMP API supplier for your needs.

Pranoprofen CoA

A Pranoprofen CoA (Certificate of Analysis) is a formal document that attests to Pranoprofen's compliance with Pranoprofen specifications and serves as a tool for batch-level quality control.

Pranoprofen CoA mostly includes findings from lab analyses of a specific batch. For each Pranoprofen CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pranoprofen may be tested according to a variety of international standards, such as European Pharmacopoeia (Pranoprofen EP), Pranoprofen JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pranoprofen USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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