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Praziquantel

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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ACTIVE PHARMA INGREDIENTS

29 API Suppliers, 10 USDMF, 13 CEP/COS, 5 EU WC, 14 NDC API, 7 VMF, 15 Listed Suppliers, $ API Reference Price

29 API Suppliers
10 USDMF
13 CEP/COS
5 EU WC
14 NDC API
7 VMF
15 Listed Suppliers
$ API Reference Price

INTERMEDIATES

2 Intermediates Suppliers

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

35 FDF Dossiers, 2 FDA Orange Book, 22 Canada, 1 Australia, 4 South Africa, 6 Listed Dossiers

35 FDF Dossiers
2 FDA Orange Book
22 Canada
1 Australia
4 South Africa
6 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Minakem, 4 SPI Pharma, 2 Seqens, 2 DKSH, 1 Pharm-RX Chemical, 4 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 10 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 1 ACG Worldwide, 8 Actylis, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 23 BASF, 10 Corel Pharma Chem, 2 DFE Pharma, 2 Finar, 6 Gangwal Chemicals, 5 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 15 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 9 Microlex e.U, 2 Nomisma Healthcare, 2 Novo Excipients, 2 Pharmatrans-Sanaq, 5 Pluviaendo, 2 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 15 Roquette, 7 Seppic, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 8 Sigachi Industries, 2 The Dow Chemical Company, 1 Valens Pharmachem, 2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

47 Coating Systems & Additives, 43 Fillers, Diluents & Binders, 28 Controlled & Modified Release, 25 Direct Compression, 20 Thickeners and Stabilizers, 17 Granulation, 13 Solubilizers, 12 Co-Processed Excipients, 12 Topical, 12 Lubricants & Glidants, 11 Film Formers & Plasticizers, 11 Disintegrants & Superdisintegrants, 11 Parenteral, 10 Taste Masking, 6 Chewable & Orodispersible Aids, 5 Empty Capsules, 5 API Stability Enhancers, 4 Vegetarian Capsules, 4 Coloring Agents, 3 Emulsifying Agents, 2 Rheology Modifiers, 1 Surfactant & Foaming Agents

DIGITAL CONTENT

12 NEWS #PharmaBuzz

media
12 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 1 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
1 Finished Drug Prices

MARKET PLACE

14 APIs, 3 FDF Dossiers

marketPlace
14 APIs
3 FDF Dossiers

REF. STANDARDS & IMPURITIES

2 EDQM , 3 USP , 4 Others

otherSolutions
2 EDQM
3 USP
4 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 180

MARKET PLACE

API

FDF

2INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

889,010

Annual Reports (USD Million)

Finished Drug Prices

177 RELATED EXCIPIENT COMPANIES

302EXCIPIENTS BY APPLICATIONS

Chemistry

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Click the button for full data set

Also known as: 55268-74-1, Biltricide, Droncit, Pyquiton, Cesol, Embay 8440

Molecular Formula

C₁₉H₂₄N₂O₂

Molecular Weight

312.4 g/mol

InChI Key

FSVJFNAIGNNGKK-UHFFFAOYSA-N

FDA UNII

6490C9U457

An anthelmintic used in most schistosome and many cestode infestations.

Praziquantel is an Anthelmintic.

1 2D Structure

Praziquantel

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one

2.1.2 InChI

InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

2.1.3 InChI Key

FSVJFNAIGNNGKK-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2

2.2 Other Identifiers

2.2.1 UNII

6490C9U457

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Biltricide

2. Cesol

3. Cisticid

4. Cysticide

5. Droncit

6. Drontsit

7. Embay 8440

8. Prasiquantel

9. Praziquantel, (+-)-isomer

10. Praziquantel, (r)-isomer

11. Praziquantel, (s)-isomer

12. Pyquiton

13. Traziquantel

2.3.2 Depositor-Supplied Synonyms

1. 55268-74-1

2. Biltricide

3. Droncit

4. Pyquiton

5. Cesol

6. Embay 8440

7. Praziquantelum

8. Azinox

9. 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1h-pyrazino[2,1-a]isoquinolin-4-one

10. 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino[2,1-a]isoquinolin-4-one

11. Embay-8440

12. Mls000038419

13. Praziquantel (biltricide)

14. Mfcd00058531

15. 135526-78-2

16. Nsc-757285

17. Smr000037139

18. 2-(cyclohexanecarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino[2,1-a]isoquinolin-4-one

19. 2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1h-pyrazino[2,1-a]isoquinolin-4(11bh)-one

20. 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4-one

21. 4h-pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-

22. Cysticide

23. Cutter Tape Tabs

24. 2-cyclohexanecarbonyl-1h,2h,3h,4h,6h,7h,11bh-piperazino[2,1-a]isoquinolin-4-one

25. Distocide

26. Prazinon

27. 6490c9u457

28. Dsstox_cid_1182

29. Dsstox_rid_75995

30. Dsstox_gsid_21182

31. Praziquantelum [inn-latin]

32. Cutter

33. 4h-pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-

34. Biltricide (tn)

35. Ccris 4114

36. (+/-)-praziquantel

37. Sr-01000003100

38. Einecs 259-559-6

39. Brn 0761557

40. Bay-8440

41. Praziquantel (jan/usp/inn)

42. Praziquantel,(s)

43. Unii-6490c9u457

44. Ncgc00016877-01

45. Prestwick_402

46. Cas-55268-74-1

47. Praziquantel 100 Microg/ml In Acetonitrile

48. (+-)-praziquantel

49. Praziquantel [usan:usp:inn:ban:jan]

50. Spectrum_001119

51. Opera_id_378

52. Prestwick0_000260

53. Prestwick1_000260

54. Prestwick2_000260

55. Prestwick3_000260

56. Spectrum2_001288

57. Spectrum3_000550

58. Spectrum4_000482

59. Spectrum5_001064

60. Praziquantel [mi]

61. Praziquantel [inn]

62. Praziquantel [jan]

63. Chembl976

64. P 4668

65. Praziquantel [usan]

66. Cid_4891

67. Praziquantel [vandf]

68. Lopac0_000909

69. Oprea1_163497

70. Schembl44153

71. Bspbio_000080

72. Bspbio_002199

73. Kbiogr_000963

74. Kbioss_001599

75. Praziquantel [mart.]

76. 5-24-03-00361 (beilstein Handbook Reference)

77. Mls000028528

78. Mls001201812

79. Mls001304085

80. Mls002548849

81. Mls006011880

82. Divk1c_000130

83. Praziquantel [usp-rs]

84. Praziquantel [who-dd]

85. Praziquantel [who-ip]

86. Spectrum1500494

87. Spbio_001295

88. Spbio_002299

89. Praziquantel-(cyclohexyl-d11)

90. Bpbio1_000088

91. Dtxsid9021182

92. Schembl16019896

93. Bdbm74574

94. Chebi:91583

95. Hms500g12

96. Kbio1_000130

97. Kbio2_001599

98. Kbio2_004167

99. Kbio2_006735

100. Kbio3_001699

101. Praziquantel [green Book]

102. Ninds_000130

103. Glxc-26256

104. Hms1568d22

105. Hms1920j06

106. Hms2090j19

107. Hms2092a09

108. Hms2095d22

109. Hms3259k07

110. Hms3262f20

111. Hms3655o19

112. Hms3712d22

113. Pharmakon1600-01500494

114. Praziquantel [orange Book]

115. Praziquantel For System Suitability

116. Praziquantel [ep Monograph]

117. Praziquantel [usp Impurity]

118. Amy16524

119. Bcp17829

120. Bcp28525

121. Bcp30228

122. Hy-b0244

123. Wzb34336

124. Praziquantel [usp Monograph]

125. Tox21_110660

126. Tox21_201950

127. Tox21_302927

128. Tox21_500909

129. Ccg-39773

130. Nsc757285

131. Praziquantel, Anthelminic, Neurogenic

132. S1691

133. Stk030186

134. Praziquantelum [who-ip Latin]

135. Akos000541869

136. Akos016398525

137. Broadline Component Praziquantel

138. Profender Component Praziquantel

139. Tox21_110660_1

140. Ac-8426

141. Db01058

142. Lp00909

143. Nc00468

144. Nsc 757285

145. Sb49202

146. Sdccgsbi-0050884.p005

147. 2-(cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4h-pyrazinoe(2,1a)isoquinolin-4-one

148. Idi1_000130

149. Ncgc00015818-04

150. Ncgc00015818-05

151. Ncgc00015818-06

152. Ncgc00015818-07

153. Ncgc00015818-08

154. Ncgc00015818-11

155. Ncgc00015818-12

156. Ncgc00015818-14

157. Ncgc00015818-15

158. Ncgc00015818-26

159. Ncgc00089733-02

160. Ncgc00089733-03

161. Ncgc00089733-04

162. Ncgc00089733-05

163. Ncgc00256422-01

164. Ncgc00259499-01

165. Ncgc00261594-01

166. As-12459

167. Bp166192

168. Praziquantel Component Of Broadline

169. Praziquantel Component Of Profender

170. Sy052322

171. Sbi-0050884.p004

172. Db-052707

173. Praziquantel (ema Epar: Veterinary)

174. (s)-praziquantel; Praziquantel, (s)-isomer

175. Ab00052075

176. Eu-0100909

177. Ft-0630676

178. P2125

179. Sw196645-3

180. 1h-pyrazino[2,1-a]isoquinolin-4(11bh)-one

181. 2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro-

182. C07367

183. D00471

184. Ab00052075-13

185. Ab00052075-15

186. Ab00052075_16

187. Ab00052075_17

188. Praziquantel, Vetranal(tm), Analytical Standard

189. 268p741

190. A830562

191. Q424145

192. Praziquantel, Antibiotic For Culture Media Use Only

193. Q-201612

194. Sr-01000003100-3

195. Sr-01000003100-5

196. Sr-01000003100-7

197. Brd-a21858158-001-05-2

198. Brd-a21858158-001-16-9

199. Sr-01000003100-16

200. F0037-0136

201. Z1563145961

202. Praziquantel, European Pharmacopoeia (ep) Reference Standard

203. Praziquantel, United States Pharmacopeia (usp) Reference Standard

204. 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4h-pyrazino[2,1-a]-isoquinolin-4-one

205. 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino-[2,1- A]isoquinolin-4-one

206. 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1h-pyrazino[2,1-a]isoquinolin-4-one

207. 2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4-one

208. Praziquantel For System Suitability, European Pharmacopoeia (ep) Reference Standard

209. Praziquantel, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₂₄N₂O₂
Molecular Weight	312.4 g/mol
XLogP3	2.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	312.183778013 g/mol
Monoisotopic Mass	312.183778013 g/mol
Topological Polar Surface Area	40.6 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	472
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Biltricide
PubMed Health	Praziquantel (By mouth)
Drug Classes	Anthelmintic
Drug Label	BILTRICIDE (praziquantel) is a trematodicide provided in tablet form for the oral treatment of schistosome infections and infections due to liver fluke.BILTRICIDE (praziquantel) is 2-(cyclohexylcarbonyl)-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2, 1...
Active Ingredient	Praziquantel
Dosage Form	Tablet
Route	Oral
Strength	600mg
Market Status	Prescription
Company	Bayer Hlthcare

2 of 2
Drug Name	Biltricide
PubMed Health	Praziquantel (By mouth)
Drug Classes	Anthelmintic
Drug Label	BILTRICIDE (praziquantel) is a trematodicide provided in tablet form for the oral treatment of schistosome infections and infections due to liver fluke.BILTRICIDE (praziquantel) is 2-(cyclohexylcarbonyl)-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2, 1...
Active Ingredient	Praziquantel
Dosage Form	Tablet
Route	Oral
Strength	600mg
Market Status	Prescription
Company	Bayer Hlthcare

4.2 Drug Indication

For the treatment of infections due to all species of schistosoma.

FDA Label

5 Pharmacology and Biochemistry

5.1 Pharmacology

Praziquantel is an anthelmintic used in most schistosome and many cestode infestations. Praziquantel effects the permeability of the cell membrane resulting in the contraction of schistosomes. The drug further causes vacuolization and disintegration of the schistosome tegument. The effect is more marked on adult worms compared to young worms. An increased calcium influx may play an important role. Secondary effects are inhibition of glucose uptake, lowering of glycogen levels and stimulation of lactate release. The action of praziquantel is limited very specifically to trematodes and cestodes; nematodes (including filariae) are not affected.

5.2 MeSH Pharmacological Classification

Anthelmintics

Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. (See all compounds classified as Anthelmintics.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

PRAZIQUANTEL

5.3.2 FDA UNII

6490C9U457

5.3.3 Pharmacological Classes

Anthelmintic [EPC]

5.4 ATC Code

P - Antiparasitic products, insecticides and repellents

P02 - Anthelmintics

P02B - Antitrematodals

P02BA - Quinoline derivatives and related substances

P02BA01 - Praziquantel

5.5 Absorption, Distribution and Excretion

Absorption

Rapidly absorbed (80%)

5.6 Metabolism/Metabolites

renal

5.7 Biological Half-Life

0.8-1.5 hours (in serum)

5.8 Mechanism of Action

Praziquantel works by causing severe spasms and paralysis of the worms' muscles. This paralysis is accompanied - and probably caused - by a rapid Ca 2+ influx inside the schistosome. Morphological alterations are another early effect of praziquantel. These morphological alterations are accompanied by an increased exposure of schistosome antigens at the parasite surface. The worms are then either completely destroyed in the intestine or passed in the stool. An interesting quirk of praziquantel is that it is relatively ineffective against juvenile schistosomes. While initially effective, effectiveness against schistosomes decreases until it reaches a minimum at 3-4 weeks. Effectiveness then increases again until it is once again fully effective at 6-7 weeks. Glutathione S-transferase (GST), an essential detoxification enzyme in parasitic helminths, is a major vaccine target and a drug target against schistosomiasis. Schistosome calcium ion channels are currently the only known target of praziquantel.

API SUPPLIERS

01

LGM Pharma

U.S.A

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Rochem International Inc

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Seqens

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Jai Radhe Sales

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Solara Active Pharma Sciences

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06

Shanghai Desano Bio-Pharmaceutical

China

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07

Merck Group

Germany

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Cipla

India

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Zhejiang Hisun Pharmaceutical

China

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Micro Labs Limited

India

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Listed Suppliers

01

LGM Pharma

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About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.

02

Rochem International Inc

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About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.

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About the Company : Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling ...

Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling up and manufacturing drug substances from the pre-clinical phase to the commercial phase. It offers a large portfolio of APIs and proprietary products. Seqens also develops custom solutions and ingredients for the most demanding industries, such as healthcare, electronics and cosmetics. Its unique range of technologies enables it to manufacture complex molecules for small- and large-scale demands. It operates 24 industrial plants and 10 R&D centres across the globe.

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About the Company : Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete ...

Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete sourcing solutions for pharmaceutical products from India, including technical and regulatory assistance. It believes in providing its customers with high-quality products at reasonable prices. It has always endeavored to achieve global standards in the field of pharmaceuticals and has carved out a niche for itself through new methods based on current market needs. Today, it has established itself as a truly global company, with exports to almost every continent.

05

Alivira Animal Health

India

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06

Beloorbayir Biotech

India

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07

Cipla

India

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08

Delta Finochem

India

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Gurvey & Berry

Canada

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Hebei Veyong Pharmaceutical

China

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API Reference Price

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MAHARASHTRA","supplier":"TIANCHEN HANGZHOU TRADING ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"LEBEN LABORATORIES PRIVATE ","customerCountry":"INDIA","quantity":"550.00","actualQuantity":"550","unit":"KGS","unitRateFc":"62.5","totalValueFC":"34737.9","currency":"USD","unitRateINR":"5259.4","date":"08-Nov-2023","totalValueINR":"2892656.25","totalValueInUsd":"34737.9","indian_port":"JNPT","hs_no":"29339990","bill_no":"8673131","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ROOM 2409,NO.136, QINGCHUN ROAD,GONGSHU DISTRICT,HANGZHOU.SDNF CHINA","customerAddress":"L-4, PHASE-III,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702233000,"product":"FOC VALUE FOR CUSTOMS PURPOSE PRAZIQUANTEL MICRONIZED","address":"BIOCON SEZ, BIOCON PARK,PLOT NO.2 3","city":"","supplier":"BOEHRINGER INGELHEIM ANIMAL HEALTH DO BRASIL LTDA","supplierCountry":"BRAZIL","foreign_port":"N\/A","customer":"SYNGENE INTERNATIONAL LIMITED","customerCountry":"INDIA","quantity":"2.50","actualQuantity":"2500","unit":"GMS","unitRateFc":"1.1","totalValueFC":"2671.5","currency":"USD","unitRateINR":"89","date":"11-Dec-2023","totalValueINR":"222383","totalValueInUsd":"2671.5","indian_port":"Biocon-SEZ","hs_no":"29339990","bill_no":"1016785","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Micronized","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"BIOCON SEZ, BIOCON PARK,PLOT NO.2 3"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709058600,"product":"PRAZIQUANTEL USP","address":"25, PULIYUR II MAIN ROAD,","city":"CHENNAI, TAMILNADU","supplier":"HANGZHOU DAWN RAY ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"MEDOPHARM PRIVATE LIMITED","customerCountry":"INDIA","quantity":"125.00","actualQuantity":"125","unit":"KGS","unitRateFc":"71","totalValueFC":"8974.1","currency":"USD","unitRateINR":"5956.9","date":"28-Feb-2024","totalValueINR":"744612.5","totalValueInUsd":"8974.1","indian_port":"Madras Air","hs_no":"29332990","bill_no":"2342745","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"1613 GUANGYIN BUILDING, NO.42E.FENGQI ROAD, HANGZHOUSDNF CHINA","customerAddress":"25, PULIYUR II MAIN ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714415400,"product":"PRAZIQUANTEL","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"ZHEJIANG HISUN PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"PAR PHARMACEUTICAL","customerCountry":"INDIA","quantity":"80.00","actualQuantity":"80","unit":"KGS","unitRateFc":"980","totalValueFC":"79238.1","currency":"USD","unitRateINR":"82712","date":"30-Apr-2024","totalValueINR":"6616960","totalValueInUsd":"79238.1","indian_port":"Madras Air","hs_no":"29349990","bill_no":"3270051","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"CO.LTD., NO.18,4TH HAIBIN ROAD, RUDONG,NANTONG, JIANGSU CHINA","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714415400,"product":"PRAZIQUANTEL USP","address":"B-106,TECHNO CITY,X 4\/1,TTC AREA","city":"NAVI MUMBAI, MAHARASHTRA","supplier":"SHENZHEN ROYAL GOLDEN SUN IMPORT AND EXPORT CO. LT","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"CELOGEN PHARMA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"2108.80","actualQuantity":"2108.8","unit":"KGS","unitRateFc":"63.6","totalValueFC":"135446.9","currency":"USD","unitRateINR":"5363.6","date":"30-Apr-2024","totalValueINR":"11310801.86","totalValueInUsd":"135446.9","indian_port":"Bombay Air","hs_no":"29411090","bill_no":"3265952","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"D. RM1001A, China Railway South Headquarters Building, No. 3333, Zhongxin Road, Azure Coast Community, Yu CHINA","customerAddress":"B-106,TECHNO CITY,X 4\/1,TTC AREA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717353000,"product":"PRAZIQUANTEL USP","address":"B-106,TECHNO CITY,X 4\/1,TTC AREA","city":"NAVI MUMBAI, MAHARASHTRA","supplier":"SHENZHEN ROYAL GOLDEN SUN IMPORT AND EXPORT CO. LT","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"CELOGEN PHARMA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"72.7","totalValueFC":"14687.6","currency":"USD","unitRateINR":"6130.6","date":"03-Jun-2024","totalValueINR":"1226111.6","totalValueInUsd":"14687.6","indian_port":"Bombay Air","hs_no":"29411090","bill_no":"3809790","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"D. RM1001A, China Railway South Headquarters Building, No. 3333, Zhongxin Road, Azure Coast Community, Yu CHINA","customerAddress":"B-106,TECHNO CITY,X 4\/1,TTC AREA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718908200,"product":"PRAZIQUANTEL RELATED COMPOUND A(QTY: 2 X 0.1G, VALUE USD: 32.83\/EACH)(FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL","supplierCountry":"INDIA","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0002","unit":"KGS","unitRateFc":"328300","totalValueFC":"67.5","currency":"USD","unitRateINR":"28169850","date":"21-Jun-2024","totalValueINR":"5633.97","totalValueInUsd":"67.5","indian_port":"Hyderabad Air","hs_no":"29335990","bill_no":"4117205","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718908200,"product":"PRAZIQUANTEL RELATED COMPOUND B (QTY: 1 X 50MG, VALUE: USD 903)(FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL","supplierCountry":"INDIA","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.00005","unit":"KGS","unitRateFc":"18060000","totalValueFC":"928.2","currency":"USD","unitRateINR":"1549641600","date":"21-Jun-2024","totalValueINR":"77482.08","totalValueInUsd":"928.2","indian_port":"Hyderabad Air","hs_no":"29335990","bill_no":"4117205","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718908200,"product":"PRAZIQUANTEL RELATED COMPOUND C (QTY: 1 X 50MG, VALUE USD: 903)(FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL","supplierCountry":"INDIA","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.00005","unit":"KGS","unitRateFc":"18060000","totalValueFC":"928.2","currency":"USD","unitRateINR":"1549641600","date":"21-Jun-2024","totalValueINR":"77482.08","totalValueInUsd":"928.2","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"4117205","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728930600,"product":"PRAZIQUANTEL EP MICRONISED","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"ALIVIRA ANIMAL HEALTH","supplierCountry":"INDIA","foreign_port":"RPCIPL SEZ","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"11.00","actualQuantity":"11","unit":"KGS","unitRateFc":"221","totalValueFC":"2454.6","currency":"USD","unitRateINR":"18750","date":"15-Oct-2024","totalValueINR":"206250","totalValueInUsd":"2454.6","indian_port":"Vizag-RPCIPL SEZ","hs_no":"29420090","bill_no":"6122865","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Micronized","supplierPort":"RPCIPL SEZ","supplierAddress":"Plot No.104 Ramky Pharma City India SEZ, JNPC, Parawada Visakhapatnam SDNF India","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732300200,"product":"PRAZIQUANTEL","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"ZHEJIANG HISUN PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"PAR PHARMACEUTICAL","customerCountry":"INDIA","quantity":"80.00","actualQuantity":"80","unit":"KGS","unitRateFc":"980","totalValueFC":"79293.6","currency":"USD","unitRateINR":"83643","date":"23-Nov-2024","totalValueINR":"6691440","totalValueInUsd":"79293.6","indian_port":"Madras Air","hs_no":"29349990","bill_no":"6835914","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"CO.LTD., NO.18, 4TH HAIBIN ROAD, RUDONG, NANTONG, JIANGSU CHINA","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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ABOUT THIS PAGE

Praziquantel Manufacturers

A Praziquantel manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Praziquantel, including repackagers and relabelers. The FDA regulates Praziquantel manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Praziquantel API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Praziquantel manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Praziquantel Suppliers

A Praziquantel supplier is an individual or a company that provides Praziquantel active pharmaceutical ingredient (API) or Praziquantel finished formulations upon request. The Praziquantel suppliers may include Praziquantel API manufacturers, exporters, distributors and traders.

click here to find a list of Praziquantel suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Praziquantel USDMF

A Praziquantel DMF (Drug Master File) is a document detailing the whole manufacturing process of Praziquantel active pharmaceutical ingredient (API) in detail. Different forms of Praziquantel DMFs exist exist since differing nations have different regulations, such as Praziquantel USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Praziquantel DMF submitted to regulatory agencies in the US is known as a USDMF. Praziquantel USDMF includes data on Praziquantel's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Praziquantel USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Praziquantel suppliers with USDMF on PharmaCompass.

Praziquantel CEP

A Praziquantel CEP of the European Pharmacopoeia monograph is often referred to as a Praziquantel Certificate of Suitability (COS). The purpose of a Praziquantel CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Praziquantel EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Praziquantel to their clients by showing that a Praziquantel CEP has been issued for it. The manufacturer submits a Praziquantel CEP (COS) as part of the market authorization procedure, and it takes on the role of a Praziquantel CEP holder for the record. Additionally, the data presented in the Praziquantel CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Praziquantel DMF.

A Praziquantel CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Praziquantel CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Praziquantel suppliers with CEP (COS) on PharmaCompass.

Praziquantel WC

A Praziquantel written confirmation (Praziquantel WC) is an official document issued by a regulatory agency to a Praziquantel manufacturer, verifying that the manufacturing facility of a Praziquantel active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Praziquantel APIs or Praziquantel finished pharmaceutical products to another nation, regulatory agencies frequently require a Praziquantel WC (written confirmation) as part of the regulatory process.

click here to find a list of Praziquantel suppliers with Written Confirmation (WC) on PharmaCompass.

Praziquantel NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Praziquantel as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Praziquantel API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Praziquantel as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Praziquantel and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Praziquantel NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Praziquantel suppliers with NDC on PharmaCompass.

Praziquantel GMP

Praziquantel Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Praziquantel GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Praziquantel GMP manufacturer or Praziquantel GMP API supplier for your needs.

Praziquantel CoA

A Praziquantel CoA (Certificate of Analysis) is a formal document that attests to Praziquantel's compliance with Praziquantel specifications and serves as a tool for batch-level quality control.

Praziquantel CoA mostly includes findings from lab analyses of a specific batch. For each Praziquantel CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Praziquantel may be tested according to a variety of international standards, such as European Pharmacopoeia (Praziquantel EP), Praziquantel JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Praziquantel USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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ACTIVE PHARMA INGREDIENTS

29 API Suppliers

10 USDMF

13 CEP/COS

5 EU WC

14 NDC API

7 VMF

15 Listed Suppliers

$ API Reference Price

INTERMEDIATES

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

35 FDF Dossiers

2 FDA Orange Book

22 Canada

1 Australia

4 South Africa

6 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Minakem

4 SPI Pharma

2 Seqens

2 DKSH

1 Pharm-RX Chemical

4 Faran Shimi Pharmaceutical

1 Boai NKY Pharmaceuticals Ltd

10 Gangwal Healthcare

1 Nanjing Well Pharmaceutical

1 Pfanstiehl

1 ACG Worldwide

8 Actylis

4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

23 BASF

10 Corel Pharma Chem

2 DFE Pharma

2 Finar

6 Gangwal Chemicals

5 Ideal Cures Pvt Ltd

2 Ingredion Pharma Solutions

15 Kerry

3 Kima Chemical

6 Lonza Capsugel

9 Microlex e.U

2 Nomisma Healthcare

2 Novo Excipients

2 Pharmatrans-Sanaq

5 Pluviaendo

2 Prachin Chemical

1 Qianhao Chemical (Hebei) Co., Ltd

1 Qualicaps

15 Roquette

7 Seppic

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

8 Sigachi Industries

2 The Dow Chemical Company

1 Valens Pharmachem

2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

47 Coating Systems & Additives

43 Fillers, Diluents & Binders

28 Controlled & Modified Release

25 Direct Compression

20 Thickeners and Stabilizers

17 Granulation

13 Solubilizers

12 Co-Processed Excipients

12 Topical

12 Lubricants & Glidants

11 Film Formers & Plasticizers

11 Disintegrants & Superdisintegrants

11 Parenteral

10 Taste Masking

6 Chewable & Orodispersible Aids

5 Empty Capsules

5 API Stability Enhancers