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Chemistry

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Also known as: 346688-38-8, 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine, 4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine, Acr16, Acr-16, 4-(3-methylsulfonylphenyl)-1-propylpiperidine
Molecular Formula
C15H23NO2S
Molecular Weight
281.4  g/mol
InChI Key
YGKUEOZJFIXDGI-UHFFFAOYSA-N
FDA UNII
HD4TW8S2VK

Pridopidine
Pridopidine has been used in trials studying the treatment of Huntington's Disease.
1 2D Structure

Pridopidine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-(3-methylsulfonylphenyl)-1-propylpiperidine
2.1.2 InChI
InChI=1S/C15H23NO2S/c1-3-9-16-10-7-13(8-11-16)14-5-4-6-15(12-14)19(2,17)18/h4-6,12-13H,3,7-11H2,1-2H3
2.1.3 InChI Key
YGKUEOZJFIXDGI-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCN1CCC(CC1)C2=CC(=CC=C2)S(=O)(=O)C
2.2 Other Identifiers
2.2.1 UNII
HD4TW8S2VK
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine

2. 4-(3-methanesulfonylphenyl)-1-propylpiperidine

3. Acr16 Compound

4. Huntexil

2.3.2 Depositor-Supplied Synonyms

1. 346688-38-8

2. 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine

3. 4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine

4. Acr16

5. Acr-16

6. 4-(3-methylsulfonylphenyl)-1-propylpiperidine

7. Hd4tw8s2vk

8. Chembl596802

9. Fr310826

10. Unii-hd4tw8s2vk

11. Acr16 Compound

12. Acr 16

13. Pridopidine [usan]

14. Pridopidine [usan:inn]

15. Pridopidine [mi]

16. Pridopidine [inn]

17. Pridopidine (usan/inn)

18. 4-(3-methanesulfonyl-phenyl)-1-propyl-piperidine

19. Pridopidine [who-dd]

20. Schembl166748

21. Asp2314

22. Dtxsid90188225

23. Bdbm50308028

24. Mfcd09835586

25. Zinc22063703

26. Akos015891431

27. Db11947

28. Ncgc00386586-01

29. As-50146

30. Hy-10684

31. Db-014417

32. Cs-0002733

33. Ft-0672149

34. 4-(3-methanesulfonylphenyl)-1-propylpiperidine

35. D09953

36. O11067

37. Q7242858

38. Piperidine, 4-(3-(methylsulfonyl)phenyl)-1-propyl-

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 281.4 g/mol
Molecular Formula C15H23NO2S
XLogP32.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass281.14495015 g/mol
Monoisotopic Mass281.14495015 g/mol
Topological Polar Surface Area45.8 Ų
Heavy Atom Count19
Formal Charge0
Complexity366
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Investigated for use/treatment in huntington's disease and schizophrenia and schizoaffective disorders.


5 Pharmacology and Biochemistry
5.1 Mechanism of Action

ACR16 belongs to a novel class of drugs, characterised as dopaminergic stabilisers, CNS active compounds that can both enhance and counteract dopaminergic effects in the brain depending on the initial level of dopaminergic activity. ARC16 works to "smooth" the many functions of this neurotransmitter chemical in striatum and other areas of the brain. Thus they have the ability to stabilize behavioural and motor disturbances caused by neurological and psychiatric disorders. They do this in pathological states without compromising normal thought processes or motor functions.


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ABOUT THIS PAGE

Pridopidine Manufacturers

A Pridopidine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pridopidine, including repackagers and relabelers. The FDA regulates Pridopidine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pridopidine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Pridopidine Suppliers

A Pridopidine supplier is an individual or a company that provides Pridopidine active pharmaceutical ingredient (API) or Pridopidine finished formulations upon request. The Pridopidine suppliers may include Pridopidine API manufacturers, exporters, distributors and traders.

Pridopidine GMP

Pridopidine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pridopidine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pridopidine GMP manufacturer or Pridopidine GMP API supplier for your needs.

Pridopidine CoA

A Pridopidine CoA (Certificate of Analysis) is a formal document that attests to Pridopidine's compliance with Pridopidine specifications and serves as a tool for batch-level quality control.

Pridopidine CoA mostly includes findings from lab analyses of a specific batch. For each Pridopidine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pridopidine may be tested according to a variety of international standards, such as European Pharmacopoeia (Pridopidine EP), Pridopidine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pridopidine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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