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Chemistry

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Also known as: 58-33-3, Promethazine hcl, Phenergan, N,n-dimethyl-1-(10h-phenothiazin-10-yl)propan-2-amine hydrochloride, Fenergan, Remsed
Molecular Formula
C17H21ClN2S
Molecular Weight
320.9  g/mol
InChI Key
XXPDBLUZJRXNNZ-UHFFFAOYSA-N
FDA UNII
R61ZEH7I1I

Promethazine Hydrochloride
A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
1 2D Structure

Promethazine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride
2.1.2 InChI
InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
2.1.3 InChI Key
XXPDBLUZJRXNNZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl
2.2 Other Identifiers
2.2.1 UNII
R61ZEH7I1I
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Atosil

2. Diphergan

3. Diprazin

4. Hydrochloride, Promethazine

5. Isopromethazine

6. Phenargan

7. Phenergan

8. Phensedyl

9. Pipolfen

10. Pipolphen

11. Proazamine

12. Promet

13. Prometazin

14. Promethazine

15. Prothazin

16. Pyrethia

17. Remsed

18. Rumergan

2.3.2 Depositor-Supplied Synonyms

1. 58-33-3

2. Promethazine Hcl

3. Phenergan

4. N,n-dimethyl-1-(10h-phenothiazin-10-yl)propan-2-amine Hydrochloride

5. Fenergan

6. Remsed

7. Promethazine (hydrochloride)

8. Diprasine

9. Diprazin

10. Fellozine

11. Pipolfen

12. Pipolphen

13. Ganphen

14. Plletia

15. Prometh Fortis

16. Prometh Plain

17. Promethazine.hcl

18. Mymethazine Fortis

19. Anergan 25

20. Promethacon

21. Promethegan

22. Romergan

23. Promethazine Chloride

24. Promethiazin

25. Zipan-25

26. V Gan

27. Lergigan

28. Pyrethia

29. Zipan-50

30. Promethazine Monohydrochloride

31. Hl 8700

32. N-(2-dimethylaminopropyl-1)phenothiazine Hydrochloride

33. 10-[2-(dimethylamino)propyl]phenothiazine Hydrochloride

34. N,n-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride

35. N-(2'-dimethylamino-2'-methyl)ethylphenothiazine Hydrochloride

36. R61zeh7i1i

37. 10-(3-dimethylaminoisopropyl)phenothiazine Hydrochloride

38. 3277 R.p.

39. Mls000069398

40. 10-(2-dimethylamino-1-propyl)phenothiazine Hydrochloride

41. Chebi:8462

42. Farganesse

43. Avomine

44. Nsc-231688

45. 58-33-3 (hcl)

46. Allerfen

47. Duplamin

48. Frinova

49. Goodnight

50. Hibechin

51. Histantil

52. Kinetosin

53. Phenadoz

54. Phencen

55. Primine

56. Promantine

57. Promine

58. Proneurin

59. Smr000058379

60. Soporil

61. Bonnox

62. Closin

63. Dorme

64. Prome

65. (+-)-10-(2-(dimethylamino)propyl)phenothiazine Monohydrochloride

66. Eusedon Mono

67. Phenergan Fortis

68. Dsstox_cid_1192

69. Pms Promethazine

70. Promethazine Plain

71. Dsstox_rid_76002

72. Dsstox_gsid_21192

73. 1435933-86-0

74. Anergan 50

75. Promethazine Hydrochloride 100 Microg/ml In Acetonitrile

76. Phenergan Plain

77. Promethiazin [german]

78. Ccris 5873

79. Phenergan Hydrochloride

80. Promethazine Hydrochloride [jan]

81. Promethazinehydrochloride

82. Einecs 200-375-2

83. Mfcd00012652

84. Unii-r61zeh7i1i

85. Nsc 231688

86. Genphen

87. Sr-01000002993

88. Phanergan D

89. Phenergan (tn)

90. Promethegan (tn)

91. 10-(2-dimethylaminopropyl)phenothiazine Hydrochloride

92. Component Of Mepergan

93. Promethazine Hydrochloride [usp:jan]

94. Promethazine-d3 Hcl

95. 10-(2-(dimethylamino)propyl)phenothiazine Monohydrochloride

96. Cpd000058379

97. Phenothiazine, 10-(2-(dimethylamino)-propyl)-, Hydrochloride

98. Pronase [jan]

99. Promethazine Hydrochlorine

100. Cas-58-33-3

101. Opera_id_1745

102. 10h-phenothiazine-10-ethanamine, N,n,alpha-trimethyl-, Monohydrochloride

103. Diprazinum [who-ip]

104. Schembl41904

105. Mls001074184

106. Mls002548850

107. Spectrum1500510

108. Chembl1200750

109. Dtxsid3021192

110. Promethazine Hydrochloride Solution

111. Hms1570b18

112. Hms1920l16

113. Pharmakon1600-01500510

114. Hy-b0781

115. N,n-dimethyl-1-phenothiazin-10-yl-propan-2-amine Hydrochloride

116. Phenothiazine, 10-(2-(dimethylamino)propyl)-, Monohydrochloride

117. Promethazine For Peak Identification

118. Tox21_202264

119. Tox21_302878

120. Tox21_500899

121. Nsc231688

122. Nsc757301

123. S4293

124. 10h-phenothiazine-10-ethanamine, N,n,.alpha.-trimethyl-, Monohydrochloride

125. Akos016339657

126. Ccg-207895

127. Cs-3543

128. Ks-1385

129. Lp00899

130. Nc00471

131. Nsc-757301

132. Promethazine Hydrochloride (jp17/usp)

133. Promethazine Hydrochloride [mi]

134. Rp-3389

135. 10h-phenothiazine-10-ethanamine, N,n,alpha-trimethyl-, Monohydrochloride, (+-)-

136. Ncgc00089735-04

137. Ncgc00094215-01

138. Ncgc00094215-02

139. Ncgc00094215-03

140. Ncgc00094215-04

141. Ncgc00094215-05

142. Ncgc00256588-01

143. Ncgc00259813-01

144. Ncgc00261584-01

145. Ac-12482

146. Bp166198

147. Promethazine Hydrochloride [mart.]

148. Promethazine Hydrochloride [vandf]

149. Promethazine Hydrochloride [usp-rs]

150. Promethazine Hydrochloride [who-dd]

151. Promethazine Hydrochloride [who-ip]

152. Db-053186

153. Eu-0100899

154. P2029

155. Sw197234-3

156. D00480

157. D92182

158. P 4651

159. Promethazine Hydrochloride [orange Book]

160. Promethazine Hydrochloride [ep Monograph]

161. Promethazine Hydrochloride [usp Impurity]

162. Wln: T C666 Bn Isj B1y1&n1&1 &gh

163. A831833

164. Promethazine Hydrochloride [usp Monograph]

165. Promethazini Hydrochloridum [who-ip Latin]

166. Mepergan Component Promethazine Hydrochloride

167. Sr-01000002993-2

168. Sr-01000002993-7

169. W-105399

170. Promethazine Hydrochloride Component Of Mepergan

171. Q27108086

172. F0138-3355

173. Phenergan Vc Component Promethazine Hydrochloride

174. Pherazine Dm Component Promethazine Hydrochloride

175. Pherazine Vc Component Promethazine Hydrochloride

176. Z1259273234

177. ((c)i)-promethazine-d4 Hcl (phenothiazine-1,3,7,9-d4)

178. Promethazine Dm Component Promethazine Hydrochloride

179. Promethazine Hydrochloride Component Of Phenergan Vc

180. Promethazine Hydrochloride Component Of Pherazine Dm

181. Promethazine Hydrochloride Component Of Pherazine Vc

182. Promethazine Vc Component Promethazine Hydrochloride

183. N,n-dimethyl-1-(10-phenothiazinyl)-2-propanamine Hydrochloride

184. N-(2'-dimethylamino-2'-methylaethyl)-phenothiazin Hydrochlorid

185. N-(2'-dimethylamino-2-methylethyl)phenothiazine Hydrochloride

186. Promethazine Hydrochloride Component Of Promethazine Dm

187. Promethazine Hydrochloride Component Of Promethazine Vc

188. Promethazine Hydrochloride, Vetranal(tm), Analytical Standard

189. N,n-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydron;chloride

190. (+/-)-10-(2-(dimethylamino)propyl)phenothiazine Monohydrochloride

191. 10h-phenothiazine-10-ethanamine,n,.alpha.-trimethyl-, Monohydrochloride

192. Dimethyl[1-(10h-phenothiazin-10-yl)propan-2-yl]amine Hydrochloride

193. N,n-dimethyl-1-(10h-phenothiazin-10-yl)-2-propanamine Hydrochloride

194. Promethazine Hydrochloride 1.0 Mg/ml In Dimethyl Sulfoxide (as Free Base)

195. Promethazine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

196. Promethazine Hydrochloride, Vial Of 25 Mg, Certified Reference Material

197. 10h-phenothiazine-10-ethanamine, N,n,.alpha.-trimethyl-, Monohydrochloride, (+/-)-

198. 10h-phenothiazine-10-ethanamine, N,n,alpha-trimethyl-, Hydrochloride (1:1)

199. Promethazine For Peak Identification, European Pharmacopoeia (ep) Reference Standard

200. Promethazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

201. Promethazine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 320.9 g/mol
Molecular Formula C17H21ClN2S
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass320.1113975 g/mol
Monoisotopic Mass320.1113975 g/mol
Topological Polar Surface Area31.8 Ų
Heavy Atom Count21
Formal Charge0
Complexity298
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NamePromethazine hydrochloride
Drug LabelDESCRIPTIONPromethazine hydrochloride is a racemic compound.Promethazine hydrochloride, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N,-trimethyl-, monohydrochloride, ()-with the following structural...
Active IngredientPromethazine hydrochloride
Dosage FormTablet; Syrup; Suppository; Injectable
RouteRectal; Injection; Oral
Strength25mg; 50mg/ml; 25mg/ml; 6.25mg/5ml; 50mg; 12.5mg
Market StatusPrescription
CompanyVintage Pharms; Amneal Pharms; Wockhardt; Hospira; Sun Pharm Inds; Teva Pharms Usa; Taro; Sandoz; Watson Labs; Amneal Pharms Ny; Hi Tech Pharma; Caraco; Hikma Maple; Kvk Tech; X-gen Pharms; Vintage; Emcure Pharms Usa; Perrigo New York; Luitpold; Zydus Pha

2 of 4  
Drug NamePromethazine plain
Active IngredientPromethazine hydrochloride
Dosage FormSyrup
RouteOral
Strength6.25mg/5ml
Market StatusPrescription
CompanyWockhardt

3 of 4  
Drug NamePromethazine hydrochloride
Drug LabelDESCRIPTIONPromethazine hydrochloride is a racemic compound.Promethazine hydrochloride, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N,-trimethyl-, monohydrochloride, ()-with the following structural...
Active IngredientPromethazine hydrochloride
Dosage FormTablet; Syrup; Suppository; Injectable
RouteRectal; Injection; Oral
Strength25mg; 50mg/ml; 25mg/ml; 6.25mg/5ml; 50mg; 12.5mg
Market StatusPrescription
CompanyVintage Pharms; Amneal Pharms; Wockhardt; Hospira; Sun Pharm Inds; Teva Pharms Usa; Taro; Sandoz; Watson Labs; Amneal Pharms Ny; Hi Tech Pharma; Caraco; Hikma Maple; Kvk Tech; X-gen Pharms; Vintage; Emcure Pharms Usa; Perrigo New York; Luitpold; Zydus Pha

4 of 4  
Drug NamePromethazine plain
Active IngredientPromethazine hydrochloride
Dosage FormSyrup
RouteOral
Strength6.25mg/5ml
Market StatusPrescription
CompanyWockhardt

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Allergic Agents

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)


Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)


Antipruritics

Agents, usually topical, that relieve itching (pruritus). (See all compounds classified as Antipruritics.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Phenothiazines [CS]; Phenothiazine [EPC]

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PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST,","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"183","totalValueFC":"78583.1","currency":"EUR","unitRateINR":"16351.1","date":"31-Oct-2023","totalValueINR":"6540420","totalValueInUsd":"78583.1","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"8554161","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST,","supplierAddress":"1106 BUDAPEST KERESZTURI UT 30-38 KERESZTURI, HungarySDNF Hungary","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700591400,"product":"PROMETHAZINE HYDROCHLORIDE","address":"781, INDUSTRIAL AREA,","city":"CHANDIGARH.","supplier":"EGIS PHARMACEUTICALS PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST,","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"228","totalValueFC":"25121.6","currency":"EUR","unitRateINR":"20919","date":"22-Nov-2023","totalValueINR":"2091900","totalValueInUsd":"25121.6","indian_port":"Delhi Air","hs_no":"29419090","bill_no":"8876957","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST,","supplierAddress":"1106 BUDAPEST KERESZTURI UT 30-38 ,, HUNGARYSDNF HUNGARY","customerAddress":"781, INDUSTRIAL AREA,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702060200,"product":"PROMETHAZINE HYDROCHLORIDE","address":"MEDREICH HOUSE, NO12\/8,","city":"SEVA NAGAR, BANGALORE, KARNATAKA","supplier":"EGIS PHARMACEUTICALS PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST,","customer":"MEDREICH","customerCountry":"INDIA","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"227","totalValueFC":"18683","currency":"EUR","unitRateINR":"20736.5","date":"09-Dec-2023","totalValueINR":"1555233.75","totalValueInUsd":"18683","indian_port":"Bangalore Air","hs_no":"29359090","bill_no":"9151659","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST,","supplierAddress":"1160 BUDAPEST KERESZTURI UT 30-38SDNFSDNF HUNGARY","customerAddress":"MEDREICH HOUSE, NO12\/8,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702060200,"product":"PROMETHAZINE HYDROCHLORIDE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"N\/A","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"183","totalValueFC":"40164.4","currency":"EUR","unitRateINR":"16717.1","date":"09-Dec-2023","totalValueINR":"3343410","totalValueInUsd":"40164.4","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"9150739","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST","supplierAddress":"N\/A","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706639400,"product":"PROMETHAZINE HYDROCHLORIDE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"EGIS PHARMACEUTICALS PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST,","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"11.72","actualQuantity":"11.72","unit":"KGS","unitRateFc":"183","totalValueFC":"2381.9","currency":"EUR","unitRateINR":"16890.9","date":"31-Jan-2024","totalValueINR":"197961.35","totalValueInUsd":"2381.9","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"9911675","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST,","supplierAddress":"1106 BUDAPEST KERESZTURI UT 30-38 KERESZTURI, , HungarySDNF Hungary","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718562600,"product":"PROMETHAZINE HYDROCHLORIDE","address":"SHANKAR TOWERS PLOT NO. A30,A.I.E","city":"HYDERABAD,TELANGANA","supplier":"SOLUPHARM PHARMAZEUTISCHE","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"ANTHEA PHARMA PVT LTD","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"21","totalValueFC":"581.4","currency":"EUR","unitRateINR":"1941.5","date":"17-Jun-2024","totalValueINR":"48536.25","totalValueInUsd":"581.4","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"4046736","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"ERZEUGNISSE GMBH, INDUSTRIESTRASSE3, 34212 MELSUNGENSDNF GERMANY","customerAddress":"SHANKAR TOWERS PLOT NO. A30,A.I.E"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721413800,"product":"PROMETHAZINE HYDROCHLORIDE","address":"MEDREICH HOUSE, NO12\/8,","city":"SEVA NAGAR, BANGALORE, KARNATAKA","supplier":"EGIS PHARMACEUTICALS PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST,","customer":"MEDREICH","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"227","totalValueFC":"12586.8","currency":"EUR","unitRateINR":"21042.9","date":"20-Jul-2024","totalValueINR":"1052145","totalValueInUsd":"12586.8","indian_port":"Bangalore Air","hs_no":"29359090","bill_no":"4623767","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST,","supplierAddress":"1160 BUDAPEST KERESZTURI UT 30-38SDNFSDNF HUNGARY","customerAddress":"MEDREICH HOUSE, NO12\/8,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725301800,"product":"PROMETHAZINE HYDROCHLORIDE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"EGIS PHARMACEUTICALS PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST,","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"183","totalValueFC":"81977.6","currency":"EUR","unitRateINR":"17174.6","date":"03-Sep-2024","totalValueINR":"6869820","totalValueInUsd":"81977.6","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"5393069","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST,","supplierAddress":"1106 BUDAPEST KERESZTURI UT 30-38 K ERESZTURI, , Hungary SDNF Hungary Hungary","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726597800,"product":"PROMETHAZINE HYDROCHLORIDE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR","city":"AHMEDABAD\/GUJRAT","supplier":"EGIS PHARMACEUTICALS PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST,","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"183","totalValueFC":"82763.7","currency":"EUR","unitRateINR":"17339.3","date":"18-Sep-2024","totalValueINR":"6935700","totalValueInUsd":"82763.7","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"5668781","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST,","supplierAddress":"1106 BUDAPEST KERESZTURI UT 30-38 K ERESZTURI, , Hungary SDNF Hungary","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729362600,"product":"PROMETHAZINE HYDROCHLORIDE","address":"MEDREICH HOUSE, NO12\/8,","city":"SEVA NAGAR, BANGALORE, KARNATAKA","supplier":"EGIS PHARMACEUTICALS PLC","supplierCountry":"HUNGARY","foreign_port":"BUDAPEST","customer":"MEDREICH","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"227","totalValueFC":"12555.3","currency":"EUR","unitRateINR":"21099.7","date":"20-Oct-2024","totalValueINR":"1054982.5","totalValueInUsd":"12555.3","indian_port":"Bangalore Air","hs_no":"29359090","bill_no":"6231503","productDescription":"API","marketType":"REGULATED MARKET","country":"HUNGARY","selfForZScoreResived":"Pharma Grade","supplierPort":"BUDAPEST","supplierAddress":"1106 BUDAPEST KERESXTURI UT 30-38 H UNGARY HUNGARY","customerAddress":"MEDREICH HOUSE, NO12\/8,"}]
20-Jan-2021
29-Nov-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
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Average Price
(USD/KGS)
Number of Transactions

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Drugs in Development

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Details:

Promethazine HCl and Dextromethorphan Hydrobromide-Generic is an approved oral solution, which is indicated for the patients suffering from cough.


Lead Product(s): Promethazine Hydrochloride,Dextromethorphan Hydrobromide

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Promethazine HCl-Dextromethorphan HBr-Generic

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 13, 2024

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Details : Promethazine HCl and Dextromethorphan Hydrobromide-Generic is an approved oral solution, which is indicated for the patients suffering from cough.

Brand Name : Promethazine HCl-Dextromethorphan HBr-Generic

Molecule Type : Small molecule

Upfront Cash : Not Applicable

September 13, 2024

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FDA Orange Book

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01

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RLD : No

TE Code : AB

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : TABLET;ORAL

Dosage Strength : 12.5MG

Approval Date : 2017-06-30

Application Number : 209177

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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RLD : No

TE Code : AB

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : TABLET;ORAL

Dosage Strength : 25MG

Approval Date : 2017-06-30

Application Number : 209177

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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RLD : No

TE Code : AB

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : TABLET;ORAL

Dosage Strength : 50MG

Approval Date : 2017-06-30

Application Number : 209177

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

Strides Pharma Science

04

WATSON LABS

Ireland
Duphat
Not Confirmed
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WATSON LABS

Ireland
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Duphat
Not Confirmed

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 25MG/ML

Approval Date : 1982-01-01

Application Number : 83532

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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WATSON LABS

Ireland
Duphat
Not Confirmed
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WATSON LABS

Ireland
arrow
Duphat
Not Confirmed

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : TABLET;ORAL

Dosage Strength : 50MG

Approval Date : 1982-01-01

Application Number : 85664

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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CHARTWELL RX

U.S.A
Duphat
Not Confirmed
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CHARTWELL RX

U.S.A
arrow
Duphat
Not Confirmed

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : SYRUP;ORAL

Dosage Strength : 6.25MG/5ML

Approval Date : 1998-09-25

Application Number : 40026

RX/OTC/DISCN : RX

RLD : No

TE Code : AA

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HOSPIRA

U.S.A
Duphat
Not Confirmed
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HOSPIRA

U.S.A
arrow
Duphat
Not Confirmed

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 50MG/ML

Approval Date : 2000-06-08

Application Number : 40372

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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KVK TECH

U.S.A
Duphat
Not Confirmed
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KVK TECH

U.S.A
arrow
Duphat
Not Confirmed

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : TABLET;ORAL

Dosage Strength : 12.5MG

Approval Date : 2007-05-04

Application Number : 40712

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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PHARM ASSOC

U.S.A
Duphat
Not Confirmed
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PHARM ASSOC

U.S.A
arrow
Duphat
Not Confirmed

PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE

Dosage Form : SYRUP;ORAL

Dosage Strength : 6.25MG/5ML

Approval Date : 2006-04-26

Application Number : 40643

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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Not Confirmed
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CODEINE PHOSPHATE; PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE AND CODEINE PHOSPHATE

Dosage Form : SYRUP;ORAL

Dosage Strength : 10MG/5ML;6.25MG/5ML

Approval Date : 1984-12-17

Application Number : 88875

RX/OTC/DISCN : RX

RLD : No

TE Code : AA

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South Africa

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promethazine HCl

Brand Name : Histodor

Dosage Form : TAB

Dosage Strength : 5mg

Packaging : 1000X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

02

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Promethazine HCl

Brand Name : Stilpane

Dosage Form : SYR

Dosage Strength : 6.5mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

03

Adcock Ingram Limited

South Africa
Duphat
Not Confirmed
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Adcock Ingram Limited

South Africa
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Duphat
Not Confirmed

Promethazine Hydrochloride

Brand Name : Lentogesic Syrup

Dosage Form : SYR

Dosage Strength : 120mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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Adcock Ingram Limited

South Africa
Duphat
Not Confirmed
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Adcock Ingram Limited

South Africa
arrow
Duphat
Not Confirmed

Promethazine Hydrochloride

Brand Name : Stopayne Syrup

Dosage Form : SYR

Dosage Strength : 120mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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Cipla Medpro (Pty) Ltd

South Africa
Duphat
Not Confirmed
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Cipla Medpro (Pty) Ltd

South Africa
arrow
Duphat
Not Confirmed

Promethazine Hydrochloride

Brand Name : Pynmed Pain And Fever Syrup

Dosage Form : SYR

Dosage Strength : 6.5mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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Cipla Medpro (Pty) Ltd

South Africa
Duphat
Not Confirmed
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Cipla Medpro (Pty) Ltd

South Africa
arrow
Duphat
Not Confirmed

Promethazine Hydrochloride

Brand Name : Pynmed Tablets/Tablette

Dosage Form : TAB

Dosage Strength : 6.5mg/5ml

Packaging : 100X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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Duphat
Not Confirmed
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Promethazine Hcl

Brand Name : Promethazine Hcl Fresenius 50Mg/2Ml

Dosage Form : INJ

Dosage Strength : 50mg/2ml

Packaging : 2X10mg/2ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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Duphat
Not Confirmed
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Promethazine HCl

Brand Name : Brunacod

Dosage Form : SYR

Dosage Strength : 3mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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Not Confirmed
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Promethazine HCl

Brand Name : Brunacod

Dosage Form : SYR

Dosage Strength : 3mg/5ml

Packaging : 2500X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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Not Confirmed
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Promethazine HCl

Brand Name : Brunacod

Dosage Form : SYR

Dosage Strength : 3mg/5ml

Packaging : 200X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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Listed Dossiers

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Regulatory Info :

Registration Country : India

Promethazine Hydrochloride

Brand Name :

Dosage Form : Tablet

Dosage Strength : 12.5MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Strides Pharma Science

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Packaging :

Regulatory Info :

Promethazine Hydrochloride

Dosage : Tablet

Dosage Strength : 12.5MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Strides Pharma Science

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Regulatory Info :

Registration Country : India

Promethazine Hydrochloride

Brand Name :

Dosage Form : Tablet

Dosage Strength : 25MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Strides Pharma Science

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Packaging :

Regulatory Info :

Promethazine Hydrochloride

Dosage : Tablet

Dosage Strength : 25MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Strides Pharma Science

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Regulatory Info :

Registration Country : India

Promethazine Hydrochloride

Brand Name :

Dosage Form : Tablet

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Strides Pharma Science

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Packaging :

Regulatory Info :

Promethazine Hydrochloride

Dosage : Tablet

Dosage Strength : 50MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Strides Pharma Science

04

Duphat
Not Confirmed
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Promethazine Hydrochloride

Brand Name :

Dosage Form : Oral Solution

Dosage Strength : 5MG/5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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Promethazine Hydrochloride

Dosage : Oral Solution

Dosage Strength : 5MG/5ML

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Registration Country : India

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Promethazine Hydrochloride

Brand Name : Phena

Dosage Form : INJECTION

Dosage Strength : 25MG

Packaging : 2 ML Amp

Approval Date :

Application Number : 83312

Regulatory Info : Generic

Registration Country : India

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Promethazine Hydrochloride

Dosage : INJECTION

Dosage Strength : 25MG

Brand Name : Phena

Approval Date :

Application Number : 83312

Registration Country : India

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Promethazine Hydrochloride

Brand Name :

Dosage Form : Injection

Dosage Strength : 25MG/ML

Packaging : 2ml Ampoule

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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Promethazine Hydrochloride

Dosage : Injection

Dosage Strength : 25MG/ML

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Registration Country : India

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Promethazine Hydrochloride

Brand Name :

Dosage Form : Tablet

Dosage Strength : 25MG

Packaging : 1 x 10 T

Approval Date :

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Regulatory Info :

Registration Country : India

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Promethazine Hydrochloride

Dosage : Tablet

Dosage Strength : 25MG

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Registration Country : India

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MS Pharma

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Promethazine Hydrochloride

Brand Name :

Dosage Form : SYRUP

Dosage Strength : 5MG/5ML

Packaging : Pack Size in UPM - 125 ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Jordan

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MS Pharma

Jordan
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Jordan
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Promethazine Hydrochloride

Dosage : SYRUP

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Registration Country : Jordan

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MS Pharma

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Promethazine Hydrochloride

Brand Name :

Dosage Form : TABLET

Dosage Strength : 25MG

Packaging : Pack Size in UPM - 1000 ,20

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Jordan

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Promethazine Hydrochloride

Dosage : TABLET

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Registration Country : Jordan

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Promethazine Hydrochloride

Brand Name :

Dosage Form : TABLET

Dosage Strength : 25MG

Packaging : Blister of 10s

Approval Date :

Application Number : 83312

Regulatory Info : Generic

Registration Country : India

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Promethazine Hydrochloride

Dosage : TABLET

Dosage Strength : 25MG

Brand Name :

Approval Date :

Application Number : 83312

Registration Country : India

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DOSAGE - INJECTABLE;INJECTION - 25MG/ML

USFDA APPLICATION NUMBER - 83312

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DOSAGE - INJECTABLE;INJECTION - 50MG/ML

USFDA APPLICATION NUMBER - 83312

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DOSAGE - SYRUP;ORAL - 6.25MG/5ML

USFDA APPLICATION NUMBER - 87953

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DOSAGE - SYRUP;ORAL - 5MG/5ML;6.25MG/5ML

USFDA APPLICATION NUMBER - 88761

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DOSAGE - SYRUP;ORAL - 10MG/5ML;6.25MG/5ML

USFDA APPLICATION NUMBER - 88763

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Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

Grade : Oral

Category : Controlled & Modified Release

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Virtual BoothDKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

Grade : Oral

Category : Solubilizers

Brand Name : HPC-SSL SFP

Excipient Details : HPC-SSL SFP is used as a binder and solubilizer in solid dosage forms including tablets, capsules, granules, and pellets.

Pharmacopoeia Ref : EP, JP, USP/NF, CEP, GMP, Hala...

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Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

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Brand Name : PROMETHAZINE HYDROCHLORIDE

United Kingdom
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Promethazine Hydrochloride

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 25MG/ML

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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Brand Name : PROMETHAZINE HYDROCHLORIDE

United Kingdom
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Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 50MG/ML

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RX/OTC/DISCN : RX

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Brand Name : PROMETHAZINE HYDROCHLORIDE

U.S.A
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Dosage Form : SUPPOSITORY;RECTAL

Dosage Strength : 25MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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Promethazine Hydrochloride

Dosage Form : SUPPOSITORY;RECTAL

Dosage Strength : 12.5MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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Brand Name : PROMETHEGAN

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Dosage Form : SUPPOSITORY;RECTAL

Dosage Strength : 50MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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Brand Name : PROMETHAZINE HYDROCHLORIDE

Israel
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Brand Name : PROMETHAZINE HYDROCHLORIDE

Israel
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Promethazine Hydrochloride

Dosage Form : SUPPOSITORY;RECTAL

Dosage Strength : 12.5MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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Brand Name : PROMETHAZINE HYDROCHLORIDE

Israel
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Israel
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Promethazine Hydrochloride

Dosage Form : SUPPOSITORY;RECTAL

Dosage Strength : 25MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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Brand Name : PROMETHAZINE HYDROCHLORIDE

Ireland
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Ireland
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Dosage Form : SUPPOSITORY;RECTAL

Dosage Strength : 12.5MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : DISCN

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Brand Name : PROMETHAZINE HYDROCHLORIDE

Ireland
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Promethazine Hydrochloride

Dosage Form : SUPPOSITORY;RECTAL

Dosage Strength : 25MG

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Brand Name : PROMETHAZINE HYDROCHLORIDE

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Promethazine Hydrochloride

Dosage Form : SYRUP;ORAL

Dosage Strength : 6.25MG/5ML

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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EDQM

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EDQM, Council of Europe

Promethazine for peak identification

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Promethazine for peak identification

CAS Number : 58-33-3

Quantity Per Vial : 5 mg

Sale Unit : 1

Order Code : Y0000797

Batch No : 2

Price (€) : 79

Storage : +5°C ± 3°C

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EDQM, Council of Europe

Promethazine impurity D

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Promethazine impurity D

CAS Number : n/a

Quantity Per Vial : 35 mg

Sale Unit : 1

Order Code : Y0000769

Batch No : 3

Price (€) : 79

Storage : +5°C ± 3°C

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EDQM, Council of Europe

Promethazine hydrochloride

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Promethazine hydrochloride

CAS Number : 58-33-3

Quantity Per Vial : 50 mg

Sale Unit : 1

Order Code : P3400000

Batch No : 2

Price (€) : 79

Storage : +5°C ± 3°C

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ABOUT THIS PAGE

Promethazine Hydrochloride Manufacturers

A Promethazine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Promethazine Hydrochloride, including repackagers and relabelers. The FDA regulates Promethazine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Promethazine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Promethazine Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Promethazine Hydrochloride Suppliers

A Promethazine Hydrochloride supplier is an individual or a company that provides Promethazine Hydrochloride active pharmaceutical ingredient (API) or Promethazine Hydrochloride finished formulations upon request. The Promethazine Hydrochloride suppliers may include Promethazine Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Promethazine Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Promethazine Hydrochloride USDMF

A Promethazine Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Promethazine Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Promethazine Hydrochloride DMFs exist exist since differing nations have different regulations, such as Promethazine Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Promethazine Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Promethazine Hydrochloride USDMF includes data on Promethazine Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Promethazine Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Promethazine Hydrochloride suppliers with USDMF on PharmaCompass.

Promethazine Hydrochloride JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Promethazine Hydrochloride Drug Master File in Japan (Promethazine Hydrochloride JDMF) empowers Promethazine Hydrochloride API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Promethazine Hydrochloride JDMF during the approval evaluation for pharmaceutical products. At the time of Promethazine Hydrochloride JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Promethazine Hydrochloride suppliers with JDMF on PharmaCompass.

Promethazine Hydrochloride CEP

A Promethazine Hydrochloride CEP of the European Pharmacopoeia monograph is often referred to as a Promethazine Hydrochloride Certificate of Suitability (COS). The purpose of a Promethazine Hydrochloride CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Promethazine Hydrochloride EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Promethazine Hydrochloride to their clients by showing that a Promethazine Hydrochloride CEP has been issued for it. The manufacturer submits a Promethazine Hydrochloride CEP (COS) as part of the market authorization procedure, and it takes on the role of a Promethazine Hydrochloride CEP holder for the record. Additionally, the data presented in the Promethazine Hydrochloride CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Promethazine Hydrochloride DMF.

A Promethazine Hydrochloride CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Promethazine Hydrochloride CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Promethazine Hydrochloride suppliers with CEP (COS) on PharmaCompass.

Promethazine Hydrochloride WC

A Promethazine Hydrochloride written confirmation (Promethazine Hydrochloride WC) is an official document issued by a regulatory agency to a Promethazine Hydrochloride manufacturer, verifying that the manufacturing facility of a Promethazine Hydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Promethazine Hydrochloride APIs or Promethazine Hydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Promethazine Hydrochloride WC (written confirmation) as part of the regulatory process.

click here to find a list of Promethazine Hydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

Promethazine Hydrochloride NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Promethazine Hydrochloride as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Promethazine Hydrochloride API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Promethazine Hydrochloride as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Promethazine Hydrochloride and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Promethazine Hydrochloride NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Promethazine Hydrochloride suppliers with NDC on PharmaCompass.

Promethazine Hydrochloride GMP

Promethazine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Promethazine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Promethazine Hydrochloride GMP manufacturer or Promethazine Hydrochloride GMP API supplier for your needs.

Promethazine Hydrochloride CoA

A Promethazine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Promethazine Hydrochloride's compliance with Promethazine Hydrochloride specifications and serves as a tool for batch-level quality control.

Promethazine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Promethazine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Promethazine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Promethazine Hydrochloride EP), Promethazine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Promethazine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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