Promethazine Teoclate

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

3 API Suppliers, 3 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Exports

INTERMEDIATES

1 Suppliers

1 Suppliers

DOSSIERs // Finished Dosage Formulations

1 Dossiers, 1 South Africa

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

EU WC

Listed Suppliers

API REF. PRICE (USD / KG)

100

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 17693-51-5, Promethazine 8-chlorotheophyllinate, S5pup23u26, Promethawern, Avopreg, Theophylline, 8-chloro-, compd. with 10-(2-dimethylaminopropyl)phenothiazine

Molecular Formula

C₂₄H₂₇ClN₆O₂S

Molecular Weight

499.0 g/mol

InChI Key

YCXARMXCESBEDS-UHFFFAOYSA-N

FDA UNII

S5PUP23U26

1 2D Structure

Promethazine Teoclate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

8-chloro-1,3-dimethyl-7H-purine-2,6-dione;N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine

2.1.2 InChI

InChI=1S/C17H20N2S.C7H7ClN4O2/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h4-11,13H,12H2,1-3H3;1-2H3,(H,9,10)

2.1.3 InChI Key

YCXARMXCESBEDS-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.CN1C2=C(C(=O)N(C1=O)C)NC(=N2)Cl

2.2 Other Identifiers

2.2.1 UNII

S5PUP23U26

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 17693-51-5

2. Promethazine 8-chlorotheophyllinate

3. S5pup23u26

4. Promethawern

5. Avopreg

6. Theophylline, 8-chloro-, Compd. With 10-(2-dimethylaminopropyl)phenothiazine

7. 8-chloro-1,3-dimethyl-7h-purine-2,6-dione;n,n-dimethyl-1-phenothiazin-10-ylpropan-2-amine

8. Promethazini Teoclas [inn-latin]

9. Promethazini Teoclas

10. Promethazine Chlorotheophyllinate

11. Teoclato De Prometazina

12. Teoclate De Promethazine

13. Einecs 241-691-0

14. Teoclate De Promethazine [inn-french]

15. Teoclato De Prometazina [inn-spanish]

16. Unii-s5pup23u26

17. Avomine (tn)

18. Promethazine Teoclate [inn:ban:jan]

19. Promethazine Compd. With 8-chlorotheophylline

20. 8-chloro-3,7-dihydro-1,3-dimethyl-1h-purine-2,6-dione Compd. With N,n,alpha-trimethyl-10h-phenothiazine-10-ethanamine (1:1)

21. Schembl2143003

22. Chembl3833361

23. Chebi:32059

24. Promethazine Teoclate (jan/inn)

25. Promethazine Teoclate [inn]

26. Promethazine Teoclate [jan]

27. Promethazine Teoclate [mart.]

28. 10-(2-dimethylaminopropyl)phenothiazine Compound Of 8-chlorotheophylline

29. Promethazine Teoclate [who-dd]

30. Theophylline, 8-chloro-, Compd. With 10-(2-(dimethylamino)propyl)phenothiazine (1:1)

31. 1h-purine-2,6-dione, 8-chloro-3,7-dihydro-1,3-dimethyl-, Compd. With N,n,alpha-trimethyl-10h-phenothiazine-10-ethanamine (1:1)

32. D01242

33. 693p515

34. Promethazine Compd With 8-chlorotheophylline

35. Q27288678

36. Promethazine Compd With 8-chlorotheophylline [mi]

37. 1h-purine-2,6-dione, 8-chloro-3,9-dihydro-1,3-dimethyl-, Compd. With N,n,.alpha.-trimethyl-10h-phenothiazine-10-ethanamine (1:1)

38. Phenothiazine, 10-(2-(dimethylamino)propyl)-, Compd. With 8-chlorotheophylline (1:1)

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₄H₂₇ClN₆O₂S
Molecular Weight	499.0 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	498.1604730 g/mol
Monoisotopic Mass	498.1604730 g/mol
Topological Polar Surface Area	101 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	596
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2