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Propagermanium

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1 Drugs in Development

Synopsis

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Chemistry

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Also known as: Propagermanium, 12758-40-6, Proxigermanium, Carboxyethylgermanium sesquioxide, Repagermanium, Ge 132

Molecular Formula

C₆H₁₀Ge₂O₇

Molecular Weight

339.4 g/mol

InChI Key

XEABSBMNTNXEJM-UHFFFAOYSA-N

1 2D Structure

Propagermanium

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid

2.1.2 InChI

InChI=1S/C6H10Ge2O7/c9-5(10)1-3-7(13)15-8(14)4-2-6(11)12/h1-4H2,(H,9,10)(H,11,12)

2.1.3 InChI Key

XEABSBMNTNXEJM-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O

2.2 Synonyms

2.2.1 MeSH Synonyms

1. 3,3'-(1,3-dioxo-1,3-digermoxanediyl)dipropionic Acid

2. 3-oxygermylpropionic Acid Polymer

3. Arlamol Gel

4. Beta Carboxyethylgermanium Sesquioxide

5. Bis(2-carboxyethyl)germanium Sesquioxide

6. Bis(carboxyethyl)germanium Sesquioxide

7. Carboxyethylgermanium Sesquioxide

8. Dcefsqd

9. Dicarboxyethenylgermanium Sesquioxide

10. Dihydrogen Bis(2-carboxylatoethyl)trioxodigermanate(2-)

11. Ge 132

12. Ge-132

13. Germanium-132

14. Propagermanium

15. Proxigermanium

16. Repagermanium

17. Sk 818

18. Sk-818

2.2.2 Depositor-Supplied Synonyms

1. Propagermanium

2. 12758-40-6

3. Proxigermanium

4. Carboxyethylgermanium Sesquioxide

5. Repagermanium

6. Ge 132

7. 3,3'-(1,3-dioxo-1,3-digermoxanediyl)dipropionic Acid

8. 2-carboxyethylgermasesquioxane

9. Bis(2-carboxyethylgermanium(iv) Sesquioxide)

10. Bis(2-carboxyethylgermaniumsesquioxide)

11. Bis(2-carboxyethylgermanium Sesquioxide)

12. Propanoic Acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis-

13. Dipropanoic Acid Germanium Sequioxide

14. 2-(carboxyethyl)germanium Sesquioxide

15. Beta-carboxyethylgermanium Oxide

16. 3,3'-(germanoic Anhydride) Dipropanoic Acid

17. 3,3'-(dioxodigermoxanylene) Dipropanoic Acid

18. 126595-07-1

19. 14c-proxigermanium

20. 3,3'-(1,3-dioxodigermoxane-1,3-diyl)dipropionic Acid

21. 3-[(2-carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic Acid

22. 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic Acid

23. Sk 818

24. Ccris 5469

25. Repagermanium [inn]

26. Carboxylethylgermanium Sesquioxide

27. Einecs 235-800-0

28. Nsc 267004

29. Brn 4141883

30. Unii-1q2p9to9q7

31. Bis-beta-carboxyethylgermanium Sesquioxide

32. Serocion (tn)

33. Propanoic Acid, 3,3'-(oxybis(oxogermylene))bis-

34. Mfcd00049319

35. Propionic Acid, 3,3'-(1,3-dioxodigermoxanylene)di-

36. 3,3'-(1,3-dioxodigermoxane-1,3-diyl)dipropanoic Acid

37. Dihydrogen Bis(2-carboxylatoethyl)trioxodigermanate(2-)

38. Propagermanium (jan)

39. Propagermanium [inn]

40. Germanate(2-), Bis(2-carboxylatoethyl)trioxodi-, Dihydrogen

41. Mls000028412

42. 1q2p9to9q7

43. Schembl1650976

44. Dtxsid9065316

45. Chebi:32060

46. Nsc267004

47. Akos015903696

48. Nsc-267004

49. Ncgc00164525-01

50. Ncgc00164525-02

51. As-70115

52. Smr000058405

53. Db-041866

54. Ft-0636767

55. Propanoic Acid,3'-[oxybis(oxogermylene)]bis-

56. D01626

57. D88066

58. A805716

59. Propionic Acid,3'-(1,3-dioxodigermoxanylene)di-

60. Sr-01000944781

61. Bis(2-carboxyethylgermanium(iv) Sesquioxide), 99%

62. Q7250075

63. Sr-01000944781-1

64. Propanoic Acid,3'-(1,3-dioxo-1,3-digermoxanediyl)bis-

65. 3-({[(2-carboxyethyl)(oxo)germyl]oxy}(oxo)germyl)propanoic Acid

66. 3-({[(2-carboxyethyl)(oxo)germyl]oxy(oxo)germyl)propanoic Acid

2.3 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₆H₁₀Ge₂O₇
Molecular Weight	339.4 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	8
Exact Mass	339.8859062 g/mol
Monoisotopic Mass	341.8850082 g/mol
Topological Polar Surface Area	118 Å²
Heavy Atom Count	15
Formal Charge	0
Complexity	259
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Interferon Inducers

Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons. (See all compounds classified as Interferon Inducers.)

Antineoplastic Agents

Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)

Drugs in Development