Find Propiomazine manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Largon, Propiomazine hcl, 1240-15-9, Chebi:8492, 70bo17yr03, 1-(10-(2-(dimethylamino)propyl)phenothiazin-2-yl)-1-propanone monohydrochloride
Molecular Formula
C20H25ClN2OS
Molecular Weight
376.9  g/mol
InChI Key
UGVNGSMLNPWNNA-UHFFFAOYSA-N
FDA UNII
70BO17YR03

Propiomazine
Propiomazine Hydrochloride is the hydrochloride salt form of propiomazine, a phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.
1 2D Structure

Propiomazine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one;hydrochloride
2.1.2 InChI
InChI=1S/C20H24N2OS.ClH/c1-5-18(23)15-10-11-20-17(12-15)22(13-14(2)21(3)4)16-8-6-7-9-19(16)24-20;/h6-12,14H,5,13H2,1-4H3;1H
2.1.3 InChI Key
UGVNGSMLNPWNNA-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CC(C)N(C)C.Cl
2.2 Other Identifiers
2.2.1 UNII
70BO17YR03
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Largon

2. Propiomazine

2.3.2 Depositor-Supplied Synonyms

1. Largon

2. Propiomazine Hcl

3. 1240-15-9

4. Chebi:8492

5. 70bo17yr03

6. 1-(10-(2-(dimethylamino)propyl)phenothiazin-2-yl)-1-propanone Monohydrochloride

7. 1-propanone, 1-(10-(2-(dimethylamino)propyl)-10h-phenothiazin-2-yl)-, Monohydrochloride

8. 1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one;hydrochloride

9. Unii-70bo17yr03

10. Propiomazine Hydrochloride [usp]

11. Propiomazinhydrochlorid

12. Surecn720224

13. Schembl141677

14. Chembl1201068

15. Dtxsid80872383

16. Propiomazine Hydrochloride [mi]

17. (+/-)-propiomazine Hydrochloride

18. Propiomazine Hydrochloride [mart.]

19. Propiomazine Hydrochloride [vandf]

20. Propiomazine Hydrochloride [who-dd]

21. Propiomazine Hydrochloride, (+/-)-

22. C07384

23. Propiomazine Hydrochloride [orange Book]

24. Q27108092

25. 1-propanone, 1-(10-(2-(dimethylamino)propyl)-10h-phenothiazin-2-yl)-, Hydrochloride (1:1)

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 376.9 g/mol
Molecular Formula C20H25ClN2OS
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass376.1376123 g/mol
Monoisotopic Mass376.1376123 g/mol
Topological Polar Surface Area48.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity441
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

ABOUT THIS PAGE

Looking for 1240-15-9 / Propiomazine API manufacturers, exporters & distributors?

Propiomazine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Propiomazine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Propiomazine manufacturer or Propiomazine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Propiomazine manufacturer or Propiomazine supplier.

PharmaCompass also assists you with knowing the Propiomazine API Price utilized in the formulation of products. Propiomazine API Price is not always fixed or binding as the Propiomazine Price is obtained through a variety of data sources. The Propiomazine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Propiomazine

Synonyms

Largon, Propiomazine hcl, 1240-15-9, Chebi:8492, 70bo17yr03, 1-(10-(2-(dimethylamino)propyl)phenothiazin-2-yl)-1-propanone monohydrochloride

Cas Number

1240-15-9

Unique Ingredient Identifier (UNII)

70BO17YR03

About Propiomazine

Propiomazine Hydrochloride is the hydrochloride salt form of propiomazine, a phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.

Propiomazine Manufacturers

A Propiomazine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Propiomazine, including repackagers and relabelers. The FDA regulates Propiomazine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Propiomazine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Propiomazine Suppliers

A Propiomazine supplier is an individual or a company that provides Propiomazine active pharmaceutical ingredient (API) or Propiomazine finished formulations upon request. The Propiomazine suppliers may include Propiomazine API manufacturers, exporters, distributors and traders.

Propiomazine GMP

Propiomazine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Propiomazine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Propiomazine GMP manufacturer or Propiomazine GMP API supplier for your needs.

Propiomazine CoA

A Propiomazine CoA (Certificate of Analysis) is a formal document that attests to Propiomazine's compliance with Propiomazine specifications and serves as a tool for batch-level quality control.

Propiomazine CoA mostly includes findings from lab analyses of a specific batch. For each Propiomazine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Propiomazine may be tested according to a variety of international standards, such as European Pharmacopoeia (Propiomazine EP), Propiomazine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Propiomazine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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