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Prostaglandin A1

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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Synopsis

ACTIVE PHARMA INGREDIENTS

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NDC API

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Chemistry

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Also known as: Pga1, 14152-28-4, Prosta-10,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13e,15s)-, Pga1 (prostaglandin a1), 15a-hydroxy-9-oxo-10,13e-prostadienoate, Vyr271n44p

Molecular Formula

C₂₀H₃₂O₄

Molecular Weight

336.5 g/mol

InChI Key

BGKHCLZFGPIKKU-LDDQNKHRSA-N

FDA UNII

VYR271N44P

prostaglandin A1 is a natural product found in Larix sibirica and Homo sapiens with data available.

1 2D Structure

Prostaglandin A1

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid

2.1.2 InChI

InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1

2.1.3 InChI Key

BGKHCLZFGPIKKU-LDDQNKHRSA-N

2.1.4 Canonical SMILES

CCCCCC(C=CC1C=CC(=O)C1CCCCCCC(=O)O)O

2.1.5 Isomeric SMILES

CCCCC[C@@H](/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O)O

2.2 Other Identifiers

2.2.1 UNII

VYR271N44P

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (13e,15s)-15-hydroxy-9-oxo-prosta-10,13-dien-1-oic Acid

2. Pga1

3. Prostaglandin A1, (13e,15r)-(+-)-isomer

4. Prostaglandin A1, (13e,15r)-isomer

5. Prostaglandin A1, (13e,15s)-(+-)-isomer

6. Prostaglandin A1, (8beta,12alpha,13e,15s)-isomer

2.3.2 Depositor-Supplied Synonyms

1. Pga1

2. 14152-28-4

3. Prosta-10,13-dien-1-oic Acid, 15-hydroxy-9-oxo-, (13e,15s)-

4. Pga1 (prostaglandin A1)

5. 15a-hydroxy-9-oxo-10,13e-prostadienoate

6. Vyr271n44p

7. (13e,15s)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic Acid

8. Chebi:15545

9. 15a-hydroxy-9-oxo-10,13e-prostadienoic Acid

10. 7-[(1r,2s)-2-[(e,3s)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic Acid

11. 9-oxo-15s-hydroxy-10z,13e-prostadienoic Acid

12. Pga(sub 1)

13. Pga(sup 1)

14. Prostaglandin A(sub 1)

15. Prostaglandin A(sup 1)

16. Prostaglandin E1-217

17. Prostaglandin E(sup 1)-217

18. Chembl1084644

19. Unii-vyr271n44p

20. 3-cyclopentene-1-heptanoic Acid, 2-(3-hydroxy-1-octenyl)-5-oxo-

21. Prostaglandin A1, Synthetic

22. Bspbio_001458

23. Bml1-f01

24. Schembl6417548

25. Eicosanoids_pga1_c20h32o4

26. Pga1, Prostaglandin A1, Powder

27. Prostaglandin A1 (pga1)

28. Dtxsid601347314

29. Hms1361i20

30. Hms1791i20

31. Hms1989i20

32. Hms3402i20

33. Hms3648a03

34. Prostaglandin A1 [usp-rs]

35. (13e,15s)-15-hydroxy-9-oxo-prosta-10,13-dien-1-oic Acid

36. Zinc4096507

37. Lmfa03010005

38. Ccg-208253

39. Idi1_033928

40. Ncgc00161282-01

41. Ncgc00161282-02

42. Ncgc00161282-03

43. 15-hydroxy-9-oxoprosta-10,13-dienoate

44. 15a-hydroxy-9-ketoprosta-10,13-dienoate

45. 15-hydroxy-9-oxoprosta-10,13-dienoic Acid

46. Alprostadil Impurity A [ep Impurity]

47. 15a-hydroxy-9-ketoprosta-10,13-dienoic Acid

48. Sr-01000946186

49. J-007508

50. Sr-01000946186-1

51. Brd-k04010869-001-02-6

52. Q27098093

53. (13e,15s)-15-hydroxy-9-oxo-prosta-10,13-dien-1-oate

54. 9-oxo-15s-hydroxy-prosta-10,13e-dien-1-oic Acid

55. 2-(3-hydroxy-1-octenyl)-5-oxo-3- Cyclopentene-1-heptanoate

56. 2-(3-hydroxy-1-octenyl)-5-oxo-3-cyclopentene-1-heptanoate

57. 2-(3-hydroxy-1-octenyl)-5-oxo-3- Cyclopentene-1-heptanoic Acid

58. 2-(3-hydroxy-1-octenyl)-5-oxo-3-cyclopentene-1-heptanoic Acid

59. Pga1 (prostaglandin A1) Is Known As A Cyclopentenone Prostaglandin.

60. Prostaglandin A1, United States Pharmacopeia (usp) Reference Standard

61. 7-((1r,2s)-2-((s,e)-3-hydroxyoct-1-enyl)-5-oxocyclopent-3-enyl)heptanoic Acid

62. 7-[(1r,2s)-2-[(e,3s)-3-hydroxyoct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic Acid

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.5 g/mol
XLogP3	4.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	13
Exact Mass	336.23005950 g/mol
Monoisotopic Mass	336.23005950 g/mol
Topological Polar Surface Area	74.6 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	439
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)

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ABOUT THIS PAGE

Prostaglandin A1 Manufacturers

A Prostaglandin A1 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Prostaglandin A1, including repackagers and relabelers. The FDA regulates Prostaglandin A1 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Prostaglandin A1 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Prostaglandin A1 Suppliers

A Prostaglandin A1 supplier is an individual or a company that provides Prostaglandin A1 active pharmaceutical ingredient (API) or Prostaglandin A1 finished formulations upon request. The Prostaglandin A1 suppliers may include Prostaglandin A1 API manufacturers, exporters, distributors and traders.

Prostaglandin A1 GMP

Prostaglandin A1 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Prostaglandin A1 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Prostaglandin A1 GMP manufacturer or Prostaglandin A1 GMP API supplier for your needs.

Prostaglandin A1 CoA

A Prostaglandin A1 CoA (Certificate of Analysis) is a formal document that attests to Prostaglandin A1's compliance with Prostaglandin A1 specifications and serves as a tool for batch-level quality control.

Prostaglandin A1 CoA mostly includes findings from lab analyses of a specific batch. For each Prostaglandin A1 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Prostaglandin A1 may be tested according to a variety of international standards, such as European Pharmacopoeia (Prostaglandin A1 EP), Prostaglandin A1 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Prostaglandin A1 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.