Find Prostaglandin E3 manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Pge3, 802-31-3, Zed6sbl53s, 9-oxo-11r,15s-dihydroxy-5z,13e,17z-prostatrienoic acid, Chebi:28031, (z)-7-[(1r,2r,3r)-3-hydroxy-2-[(1e,3s,5z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopentyl]hept-5-enoic acid
Molecular Formula
C20H30O5
Molecular Weight
350.4  g/mol
InChI Key
CBOMORHDRONZRN-QLOYDKTKSA-N
FDA UNII
ZED6SBL53S

Prostaglandin E3
Prostaglandin E3 is an eicosanoid that is generated by the action of cyclooxygenases on the omega-3 fatty acid eicosapentaenoic acid (EPA). Prostaglandin E3 regulates ocular pressure, exerts anti-inflammatory activities and may inhibit tumor cell proliferation. Prostaglandin E3 may be used as a biomarker for EPA to evaluate the association between EPA and its antineoplastic activity.
1 2D Structure

Prostaglandin E3

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopentyl]hept-5-enoic acid
2.1.2 InChI
InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h3-4,6-7,12-13,15-17,19,21,23H,2,5,8-11,14H2,1H3,(H,24,25)/b6-3-,7-4-,13-12+/t15-,16+,17+,19+/m0/s1
2.1.3 InChI Key
CBOMORHDRONZRN-QLOYDKTKSA-N
2.1.4 Canonical SMILES
CCC=CCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O
2.1.5 Isomeric SMILES
CC/C=C\C[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
ZED6SBL53S
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Delta(17)-pge1

2. Delta(17)-prostaglandin E1

3. Pge1, Delta(17)-

4. Pge3

2.3.2 Depositor-Supplied Synonyms

1. Pge3

2. 802-31-3

3. Zed6sbl53s

4. 9-oxo-11r,15s-dihydroxy-5z,13e,17z-prostatrienoic Acid

5. Chebi:28031

6. (z)-7-[(1r,2r,3r)-3-hydroxy-2-[(1e,3s,5z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopentyl]hept-5-enoic Acid

7. Prosta-5,13,17-trien-1-oicacid, 11,15-dihydroxy-9-oxo-, (5z,11a,13e,15s,17z)-

8. Delta(17)-pge1

9. Pge1, Delta(17)-

10. Prosta-5,13,17-trien-1-oic Acid, 11,15-dihydroxy-9-oxo-, (5z,11.alpha.,13e,15s,17z)-

11. Delta(17)-prostaglandin E1

12. (-)-prostaglandin E3

13. Unii-zed6sbl53s

14. Schembl3366416

15. Chembl2074717

16. Dtxsid301045731

17. Zinc4097122

18. Lmfa03010135

19. C06439

20. Sr-01000946848

21. Sr-01000946848-1

22. Q15708280

23. 9-oxo-11alpha,15s-dihydroxy-prosta-5z,13e,17z-trien-1-oic Acid

24. 7-[3-hydroxy-2-(3-hydroxy-1,5-octadienyl)-5-oxocyclopentyl]-5-heptenoate

25. (5z,11alpha,13e,15s,17z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic Acid

26. (5z,13e,15s,17z)-11alpha,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic Acid

27. 7-[3-hydroxy-2-(3-hydroxy-1,5-octadienyl)-5-oxocyclopentyl]-5-heptenoic Acid

28. 7-[3-hydroxy-2-(3-hydroxy-1,5-octadienyl)-5-oxocyclopentyl]-5-heptenoic Acid Stereoisomer

29. Prosta-5,13,17-trien-1-oic Acid, 11,15-dihydroxy-9-oxo-, (5z,11alpha,13e,15s,17z)-

30. (5z,11.alpha.,13e,15s,17z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic Acid

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 350.4 g/mol
Molecular Formula C20H30O5
XLogP32.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count11
Exact Mass350.20932405 g/mol
Monoisotopic Mass350.20932405 g/mol
Topological Polar Surface Area94.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity506
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Prostaglandin E3 Manufacturers

A Prostaglandin E3 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Prostaglandin E3, including repackagers and relabelers. The FDA regulates Prostaglandin E3 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Prostaglandin E3 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Prostaglandin E3 Suppliers

A Prostaglandin E3 supplier is an individual or a company that provides Prostaglandin E3 active pharmaceutical ingredient (API) or Prostaglandin E3 finished formulations upon request. The Prostaglandin E3 suppliers may include Prostaglandin E3 API manufacturers, exporters, distributors and traders.

Prostaglandin E3 GMP

Prostaglandin E3 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Prostaglandin E3 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Prostaglandin E3 GMP manufacturer or Prostaglandin E3 GMP API supplier for your needs.

Prostaglandin E3 CoA

A Prostaglandin E3 CoA (Certificate of Analysis) is a formal document that attests to Prostaglandin E3's compliance with Prostaglandin E3 specifications and serves as a tool for batch-level quality control.

Prostaglandin E3 CoA mostly includes findings from lab analyses of a specific batch. For each Prostaglandin E3 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Prostaglandin E3 may be tested according to a variety of international standards, such as European Pharmacopoeia (Prostaglandin E3 EP), Prostaglandin E3 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Prostaglandin E3 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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