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    Chemistry

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    Also known as: 179474-85-2, Resolor, Prucalopride succinat, Prucalopride (succinate), R-108512, Butanedioic acid 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide
    Molecular Formula
    C22H32ClN3O7
    Molecular Weight
    486.0  g/mol
    InChI Key
    QZRSNVSQLGRAID-UHFFFAOYSA-N
    FDA UNII
    4V2G75E1CK
    Prucalopride Succinate
    1 2D Structure

    Prucalopride Succinate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide;butanedioic acid
    2.1.2 InChI
    InChI=1S/C18H26ClN3O3.C4H6O4/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14;5-3(6)1-2-4(7)8/h11-12H,2-10,20H2,1H3,(H,21,23);1-2H2,(H,5,6)(H,7,8)
    2.1.3 InChI Key
    QZRSNVSQLGRAID-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl.C(CC(=O)O)C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    4V2G75E1CK
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4-amino-5-chloro-n-(1-(3-methoxypropyl)-4-piperidinyl)-2,3-dihydro-1-benzofuran-7-carboxamide

    2. Motegrity

    3. Prucalopride

    4. R 093877

    5. R093877

    6. Resolor

    7. Resotran

    8. Resotrans

    2.3.2 Depositor-Supplied Synonyms

    1. 179474-85-2

    2. Resolor

    3. Prucalopride Succinat

    4. Prucalopride (succinate)

    5. R-108512

    6. Butanedioic Acid 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide

    7. Prucalopride Succinate [usan]

    8. Prucalopride (as Succinate)

    9. 4v2g75e1ck

    10. 179474-85-2 (succinate)

    11. 4-amino-5-chloro-n-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide Succinate

    12. Butanedioic Acid, Compd. With 4-amino-5-chloro-2,3-dihydro-n-(1-(3-methoxypropyl)-4-piperidinyl)-7-benzofurancarboxamide (1:1)

    13. Butanedioic Acid, Compd. With 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1)

    14. Prucalopride Succinate (usan)

    15. Resotran

    16. 4-amino-5-chloro-n-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide;butanedioic Acid

    17. Resolor (tn)

    18. Unii-4v2g75e1ck

    19. R-93877

    20. Resolor Succinate

    21. Motegrity (tn)

    22. Prucalopridesuccinate

    23. R 108512

    24. Mls006011219

    25. Schembl1230437

    26. Chembl2105748

    27. Dtxsid701027749

    28. Hms3652b21

    29. Hms3885j13

    30. Bcp09320

    31. Mfcd00948731

    32. S4247

    33. Akos015994741

    34. Prucalopride Succinate [mart.]

    35. Ccg-269590

    36. Cs-3907

    37. Ks-1283

    38. Prucalopride Succinate [who-dd]

    39. 4-amino-5-chloro-n-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide,butanedioic Acid

    40. Ac-29960

    41. Butanedioic Acid 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarb

    42. Hy-12694

    43. Smr004702981

    44. Db-065276

    45. Prucalopride Succinate [orange Book]

    46. Ft-0745512

    47. Sw219198-1

    48. D10152

    49. A812449

    50. J-519956

    51. Q27260539

    52. B0084-470898

    2.4 Create Date
    2006-10-25
    3 Chemical and Physical Properties
    Molecular Weight 486.0 g/mol
    Molecular Formula C22H32ClN3O7
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count9
    Exact Mass485.1928781 g/mol
    Monoisotopic Mass485.1928781 g/mol
    Topological Polar Surface Area151 Ų
    Heavy Atom Count33
    Formal Charge0
    Complexity538
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Indication

    Resolor is indicated for symptomatic treatment of chronic constipation in adults in whom laxatives fail to provide adequate relief.

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Laxatives

    Agents that produce a soft formed stool, and relax and loosen the bowels, typically used over a protracted period, to relieve CONSTIPATION. (See all compounds classified as Laxatives.)

    Serotonin 5-HT4 Receptor Agonists

    Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT4 RECEPTORS. (See all compounds classified as Serotonin 5-HT4 Receptor Agonists.)

    5.2 ATC Code

    A06AX05

    API Reference Price

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REDDY COLONY, BANJARA HILLS,","city":"HYDERABAD,TELANGANA","supplier":"APOTEX INC","supplierCountry":"INDIA","foreign_port":"NA","customer":"SYMED LABS","customerCountry":"INDIA","quantity":"5.02","actualQuantity":"5.022","unit":"KGS","unitRateFc":"32000","totalValueFC":"164819.6","currency":"USD","unitRateINR":"2697420.6","date":"04-Jul-2023","totalValueINR":"13546445.09","totalValueInUsd":"164819.6","indian_port":"HYDERABAD AIR","hs_no":"29333200","bill_no":"0","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"H.NO. 8-2-293\/174\/3, ROAD NO. 14,, B.N. REDDY COLONY, BANJARA HILLS,"}]
    22-Feb-2021
    28-Aug-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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