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Pseudoephedrine, Triprolidine Drug Combination

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Also known as: Pseudophedrine hydrochoride mixture with triprolidine hydrochloride, 8054-27-1, Trifed, (1s,2s)-2-(methylamino)-1-phenylpropan-1-ol;2-[(e)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine;dihydrochloride, Decondine, Dtxsid401009332

Molecular Formula

C₂₉H₃₉Cl₂N₃O

Molecular Weight

516.5 g/mol

InChI Key

CNBCKNGTUYBXON-PLLJCRPXSA-N

1 2D Structure

Pseudoephedrine, Triprolidine Drug Combination

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol;2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine;dihydrochloride

2.1.2 InChI

InChI=1S/C19H22N2.C10H15NO.2ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;1-8(11-2)10(12)9-6-4-3-5-7-9;;/h2-3,6-12H,4-5,13-15H2,1H3;3-8,10-12H,1-2H3;2*1H/b18-11+;;;/t;8-,10+;;/m.0../s1

2.1.3 InChI Key

CNBCKNGTUYBXON-PLLJCRPXSA-N

2.1.4 Canonical SMILES

CC1=CC=C(C=C1)C(=CCN2CCCC2)C3=CC=CC=N3.CC(C(C1=CC=CC=C1)O)NC.Cl.Cl

2.1.5 Isomeric SMILES

CC1=CC=C(C=C1)/C(=C\CN2CCCC2)/C3=CC=CC=N3.C[C@@H]([C@H](C1=CC=CC=C1)O)NC.Cl.Cl

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Actifed

2. Pseudoephedrine - Triprolidine

3. Pseudoephedrine, Triprolidine Drug Combination

4. Trifed

2.2.2 Depositor-Supplied Synonyms

1. Pseudophedrine Hydrochoride Mixture With Triprolidine Hydrochloride

2. 8054-27-1

3. Trifed

4. (1s,2s)-2-(methylamino)-1-phenylpropan-1-ol;2-[(e)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine;dihydrochloride

5. Decondine

6. Dtxsid401009332

7. Triprolidine And Pseudoephedrine

8. Triprolidine Mixture With Pseudoephedrine

9. Pseudoephedrine Mixture With Triprolidine

10. Benzenemethanol, Alpha-((1s)-1-(methylamino)ethyl)-, Hydrochloride, (alphas)-, Mixt. With 2-((1e)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)pyridine Monohydrochloride

11. Benzenemethanol, Alpha-(1-(methylamino)ethyl)-, Hydrochloride, (s-(r*,r*))-, Mixt. With (e)-2-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)pyridine Monohydrochloride

12. Triprolidine And Pseudoephedrine Hydrochlorides

13. Pseudoephedrine Hydrochloride And Triprolidine Hydrochloride

14. Triprolidine Hydrochloride And Pseudoephedrine Hydrochloride

2.3 Create Date

2006-04-28

3 Chemical and Physical Properties

Molecular Formula	C₂₉H₃₉Cl₂N₃O
Molecular Weight	516.5 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	515.2470183 g/mol
Monoisotopic Mass	515.2470183 g/mol
Topological Polar Surface Area	48.4 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	457
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	4

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)

Expectorants

Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here. (See all compounds classified as Expectorants.)

4.2 FDA Pharmacological Classification

4.2.1 Pharmacological Classes

alpha-Adrenergic Agonist [EPC]; Adrenergic alpha-Agonists [MoA]

ABOUT THIS PAGE

Pseudoephedrine, Triprolidine Drug Combination Manufacturers

A Pseudoephedrine, Triprolidine Drug Combination manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pseudoephedrine, Triprolidine Drug Combination, including repackagers and relabelers. The FDA regulates Pseudoephedrine, Triprolidine Drug Combination manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pseudoephedrine, Triprolidine Drug Combination API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Pseudoephedrine, Triprolidine Drug Combination Suppliers

A Pseudoephedrine, Triprolidine Drug Combination supplier is an individual or a company that provides Pseudoephedrine, Triprolidine Drug Combination active pharmaceutical ingredient (API) or Pseudoephedrine, Triprolidine Drug Combination finished formulations upon request. The Pseudoephedrine, Triprolidine Drug Combination suppliers may include Pseudoephedrine, Triprolidine Drug Combination API manufacturers, exporters, distributors and traders.

Pseudoephedrine, Triprolidine Drug Combination GMP

Pseudoephedrine, Triprolidine Drug Combination Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pseudoephedrine, Triprolidine Drug Combination GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pseudoephedrine, Triprolidine Drug Combination GMP manufacturer or Pseudoephedrine, Triprolidine Drug Combination GMP API supplier for your needs.

Pseudoephedrine, Triprolidine Drug Combination CoA

A Pseudoephedrine, Triprolidine Drug Combination CoA (Certificate of Analysis) is a formal document that attests to Pseudoephedrine, Triprolidine Drug Combination's compliance with Pseudoephedrine, Triprolidine Drug Combination specifications and serves as a tool for batch-level quality control.

Pseudoephedrine, Triprolidine Drug Combination CoA mostly includes findings from lab analyses of a specific batch. For each Pseudoephedrine, Triprolidine Drug Combination CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pseudoephedrine, Triprolidine Drug Combination may be tested according to a variety of international standards, such as European Pharmacopoeia (Pseudoephedrine, Triprolidine Drug Combination EP), Pseudoephedrine, Triprolidine Drug Combination JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pseudoephedrine, Triprolidine Drug Combination USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.