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Chemistry

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Also known as: Psilocine, 4-hydroxy-n,n-dimethyltryptamine, 520-53-6, Psilotsin, Psilocyn, 3-[2-(dimethylamino)ethyl]-1h-indol-4-ol
Molecular Formula
C12H16N2O
Molecular Weight
204.27  g/mol
InChI Key
SPCIYGNTAMCTRO-UHFFFAOYSA-N
FDA UNII
CMS88KUW0G

Psilocin
psilocin is a natural product found in Conocybe velutipes, Conocybe tenera, and other organisms with data available.
1 2D Structure

Psilocin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[2-(dimethylamino)ethyl]-1H-indol-4-ol
2.1.2 InChI
InChI=1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3
2.1.3 InChI Key
SPCIYGNTAMCTRO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN(C)CCC1=CNC2=C1C(=CC=C2)O
2.2 Other Identifiers
2.2.1 UNII
CMS88KUW0G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (3-(2-dimethylamino)ethyl)indol-4-ol

2. Psilocin Hydrochloride

3. Psilocin Tartrate (1:1)

2.3.2 Depositor-Supplied Synonyms

1. Psilocine

2. 4-hydroxy-n,n-dimethyltryptamine

3. 520-53-6

4. Psilotsin

5. Psilocyn

6. 3-[2-(dimethylamino)ethyl]-1h-indol-4-ol

7. 3-(2-(dimethylamino)ethyl)indol-4-ol

8. N,n-dimethyl-4-hydroxytryptamine

9. 3-(2-(dimethylamino)ethyl)-1h-indol-4-ol

10. Cms88kuw0g

11. 4-ho-dmt

12. Chembl65547

13. Chebi:8613

14. Ncgc00247728-01

15. 1h-indol-4-ol, 3-[2-(dimethylamino)ethyl]-

16. 3-[2-(dimethylamino)ethyl]-1~{h}-indol-4-ol

17. Indol-4-ol, 3-(2-(dimethylamino)ethyl)-

18. Indol-4-ol, 3-[2-(dimethylamino)ethyl]-

19. Cx-59

20. Einecs 208-296-5

21. Unii-cms88kuw0g

22. Brn 0160503

23. Dea No. 7438

24. 91q

25. Psilocin [mi]

26. Psilocin [mart.]

27. Psilocin [who-dd]

28. 4-oh-dmt

29. Magic Mushrooms (salt/mix)

30. Dsstox_cid_28825

31. Dsstox_rid_83094

32. Dsstox_gsid_48899

33. 5-22-12-00014 (beilstein Handbook Reference)

34. Schembl194899

35. Psilocin/psilocybin (salt/mix)

36. Zinc2001

37. Dtxsid5048899

38. Gtpl11291

39. Spciygntamctro-uhfffaoysa-

40. Cx 59

41. Tox21_112894

42. Bdbm50081701

43. Akos022505992

44. En-0002

45. 3-[2-(dimethylamino)ethyl]-indol-4-ol

46. Cas-520-53-6

47. 3-[2-(dimethylamino)ethyl]-1h-indol-4-ol #

48. C08312

49. P-7800

50. 4-hydroxy-n,n-dimethyltryptamine Psilocin

51. L000675

52. Q409150

53. Psilocin, Vial Of 5 Mg, Certified Reference Material

54. Psilocin Solution, 100 Mug/ml In Methanol, Drug Standard

55. Psilocin Solution, 1.0 Mg/ml In Acetonitrile, Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 204.27 g/mol
Molecular Formula C12H16N2O
XLogP32.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass204.126263138 g/mol
Monoisotopic Mass204.126263138 g/mol
Topological Polar Surface Area39.3 Ų
Heavy Atom Count15
Formal Charge0
Complexity208
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Hallucinogens

Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise. (See all compounds classified as Hallucinogens.)


4.2 Metabolism/Metabolites

Psilocin has known human metabolites that include (2S,3S,4S,5R)-6-[[3-[2-(dimethylamino)ethyl]-1H-indol-4-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


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ABOUT THIS PAGE

Psilocin Manufacturers

A Psilocin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Psilocin, including repackagers and relabelers. The FDA regulates Psilocin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Psilocin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Psilocin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Psilocin Suppliers

A Psilocin supplier is an individual or a company that provides Psilocin active pharmaceutical ingredient (API) or Psilocin finished formulations upon request. The Psilocin suppliers may include Psilocin API manufacturers, exporters, distributors and traders.

click here to find a list of Psilocin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Psilocin USDMF

A Psilocin DMF (Drug Master File) is a document detailing the whole manufacturing process of Psilocin active pharmaceutical ingredient (API) in detail. Different forms of Psilocin DMFs exist exist since differing nations have different regulations, such as Psilocin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Psilocin DMF submitted to regulatory agencies in the US is known as a USDMF. Psilocin USDMF includes data on Psilocin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Psilocin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Psilocin suppliers with USDMF on PharmaCompass.

Psilocin GMP

Psilocin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Psilocin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Psilocin GMP manufacturer or Psilocin GMP API supplier for your needs.

Psilocin CoA

A Psilocin CoA (Certificate of Analysis) is a formal document that attests to Psilocin's compliance with Psilocin specifications and serves as a tool for batch-level quality control.

Psilocin CoA mostly includes findings from lab analyses of a specific batch. For each Psilocin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Psilocin may be tested according to a variety of international standards, such as European Pharmacopoeia (Psilocin EP), Psilocin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Psilocin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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