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Chemistry

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Also known as: 3681-99-0, Kakonein, Daidzein-8-c-glucoside, 7-hydroxy-3-(4-hydroxyphenyl)-8-((2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)-4h-chromen-4-one, Puerarin 80 mm, Chebi:8633
Molecular Formula
C21H20O9
Molecular Weight
416.4  g/mol
InChI Key
HKEAFJYKMMKDOR-VPRICQMDSA-N
FDA UNII
Z9W8997416

Puerarin
puerarin is a natural product found in Neustanthus phaseoloides, Clematis hexapetala, and other organisms with data available.
1 2D Structure

Puerarin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
2.1.2 InChI
InChI=1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1
2.1.3 InChI Key
HKEAFJYKMMKDOR-VPRICQMDSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O
2.1.5 Isomeric SMILES
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
Z9W8997416
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7,4'-dihydroxyisoflavone-8beta-glucopyranoside

2. Kakonein

2.3.2 Depositor-Supplied Synonyms

1. 3681-99-0

2. Kakonein

3. Daidzein-8-c-glucoside

4. 7-hydroxy-3-(4-hydroxyphenyl)-8-((2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)-4h-chromen-4-one

5. Puerarin 80 Mm

6. Chebi:8633

7. Npi 031g

8. Daidzein 8-c-glucoside

9. Nsc-380711

10. 7-hydroxy-3-(4-hydroxyphenyl)-8-[(2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one

11. Z9w8997416

12. Puerarin, Analytical Standard

13. Mfcd00063399

14. Ac1nqz4n

15. 8-c-glucoside

16. 8-glucosyldaidzein

17. Unii-z9w8997416

18. Kudzu Root Extract

19. Nsc 380711

20. 7,4'-dihydroxy-8-c-glucosylisoflavone

21. Brn 0064198

22. 8-glucopyranosyldaidzein

23. Puerarin [inci]

24. Puerarin [who-dd]

25. Surecn8581666

26. 4-19-00-03200 (beilstein Handbook Reference)

27. Mls002473178

28. Bidd:er0101

29. Chembl486386

30. Schembl8581666

31. Hkeafjykmmkdor-vpricqmdsa-

32. Dtxsid30958020

33. Hms2198m10

34. Puerarin, >=98.0% (hplc)

35. Hy-n0145

36. Zinc4098745

37. Bdbm50129558

38. 8-beta-d-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

39. Akos007930376

40. Akos015965556

41. Cs-6158

42. Db12290

43. Ks-5191

44. 4h-1-benzopyran-4-one, 8-beta-d-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-

45. 7-hydroxy-3-(4-hydroxyphenyl)-8-[(2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one

46. Ac-20294

47. Smr001397270

48. N1114

49. 4',7-dihydroxy-8-c-glucosylisoflavone

50. Q63408673

51. (1s)-1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4h-chromen-8-yl]-d-glucitol

52. 4h-1-benzopyran-4-one, 8-.beta.-d-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-

53. 8-(-bet.-d-glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-4h-1-benzopyran-4-one

54. 8-(beta-d-glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-4h-1-benzopyran-4-one

55. (1s)-1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4h-1-benzopyran-8-yl]-d-glucitol

56. 7-hydroxy-3-(4-hydroxyphenyl)-8-[(3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 416.4 g/mol
Molecular Formula C21H20O9
XLogP30
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count9
Rotatable Bond Count3
Exact Mass416.11073221 g/mol
Monoisotopic Mass416.11073221 g/mol
Topological Polar Surface Area157 Ų
Heavy Atom Count30
Formal Charge0
Complexity659
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


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ABOUT THIS PAGE

Puerarin Manufacturers

A Puerarin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Puerarin, including repackagers and relabelers. The FDA regulates Puerarin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Puerarin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Puerarin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Puerarin Suppliers

A Puerarin supplier is an individual or a company that provides Puerarin active pharmaceutical ingredient (API) or Puerarin finished formulations upon request. The Puerarin suppliers may include Puerarin API manufacturers, exporters, distributors and traders.

click here to find a list of Puerarin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Puerarin GMP

Puerarin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Puerarin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Puerarin GMP manufacturer or Puerarin GMP API supplier for your needs.

Puerarin CoA

A Puerarin CoA (Certificate of Analysis) is a formal document that attests to Puerarin's compliance with Puerarin specifications and serves as a tool for batch-level quality control.

Puerarin CoA mostly includes findings from lab analyses of a specific batch. For each Puerarin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Puerarin may be tested according to a variety of international standards, such as European Pharmacopoeia (Puerarin EP), Puerarin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Puerarin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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