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    Chemistry

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    Also known as: 22204-24-6, Pyrantel embonate, Antiminth, Combantrin, Pyrantel (pamoate), Cp-10,423-16
    Molecular Formula
    C34H30N2O6S
    Molecular Weight
    594.7  g/mol
    InChI Key
    AQXXZDYPVDOQEE-MXDQRGINSA-N
    FDA UNII
    81BK194Z5M
    Pyrantel Pamoate
    Broad spectrum antinematodal anthelmintic used also in veterinary medicine.
    1 2D Structure

    Pyrantel Pamoate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid;1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine
    2.1.2 InChI
    InChI=1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+
    2.1.3 InChI Key
    AQXXZDYPVDOQEE-MXDQRGINSA-N
    2.1.4 Canonical SMILES
    CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O
    2.1.5 Isomeric SMILES
    CN1CCCN=C1/C=C/C2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    81BK194Z5M
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Antiminth

    2. Combantrin

    3. Embonate, Pyrantel

    4. Embovin

    5. Pamoate, Pyrantel

    6. Pyrantel Embonate

    2.3.2 Depositor-Supplied Synonyms

    1. 22204-24-6

    2. Pyrantel Embonate

    3. Antiminth

    4. Combantrin

    5. Pyrantel (pamoate)

    6. Cp-10,423-16

    7. Pyrantel (as Pamoate)

    8. Embovin

    9. (e)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1)

    10. Nsc-355080

    11. Chebi:8655

    12. Cp 10423-16

    13. 81bk194z5m

    14. Nsc355080

    15. (e)-1-methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate)

    16. Cp-10423-16

    17. Cp-10423-18

    18. Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (e)-, Compd. With 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylic Acid) (1:1)

    19. Cobantril

    20. Sentry Hc Worm X

    21. 2-naphthalenecarboxylic Acid, 4,4'-methylenebis[3-hydroxy-, Compd. With 1,4,5,6-tetrahydro-1-methyl-2-[(1e)-2-(2-thienyl)ethenyl]pyrimidine (1:1)

    22. 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic Acid; 1-methyl-2-[(e)-2-(2-thienyl)vinyl]-5,6-dihydro-4h-pyrimidine

    23. 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic Acid;1-methyl-2-[(e)-2-thiophen-2-ylethenyl]-5,6-dihydro-4h-pyrimidine

    24. Sentry Hc Worm X Ds

    25. Einecs 244-837-1

    26. Vetscription Sure Shot 2x

    27. Nsc 355080

    28. Pyirantelpamoate

    29. Unii-81bk194z5m

    30. Pyrantel Pamoates

    31. Pyranteli Embonas

    32. Antiminth (tn)

    33. Pyrantel Pamoate [usan:usp:jan]

    34. 2-naphthalenecarboxylic Acid, 4,4'-methylenebis(3-hydroxy-, Compd. With 1,4,5,6-tetrahydro-1-methyl-2-((1e)-2-(2-thienyl)ethenyl)pyrimidine (1:1)

    35. Spectrum5_001373

    36. Pyrantel Pamoate, Bioxtra

    37. (3-hydroxy-2-naphthoate)

    38. Schembl41025

    39. 2-naphthalenecarboxylic Acid, 4,4'-methylenebis(3-hydroxy-, Compd. With (e)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)pyrimidine (1:1)

    40. Pyrantel Pamoate [mi]

    41. Spectrum1500517

    42. Pyrantel Pamoate [jan]

    43. Pyrantel Pamoate (jp17/usp)

    44. Schembl7793068

    45. Pyrantel Pamoate [usan]

    46. Chembl1599768

    47. Pyrantel Pamoate [vandf]

    48. Hms500m16

    49. Pyrantel Pamoate Sigmaultra,(s)

    50. Amy3564

    51. Dtxsid40897057

    52. Pyrantel Embonate [mart.]

    53. Pyrantel Pamoate [usp-rs]

    54. Hms1920n06

    55. Hms2090j21

    56. Hms2092e07

    57. Pharmakon1600-01500517

    58. Pyrantel Embonate [who-dd]

    59. Pyrantel Embonate [who-ip]

    60. Ccg-39242

    61. Mfcd00072037

    62. Nsc757303

    63. S2501

    64. Stl481883

    65. Pyrantel Pamoate [green Book]

    66. Akos015908224

    67. Cs-3869

    68. Nsc-757303

    69. Idi1_000254

    70. Pyrantel Embonate [ep Monograph]

    71. Pyrantel Pamoate [usp Monograph]

    72. Ncgc00094552-01

    73. Ncgc00094552-02

    74. Ncgc00094552-03

    75. Pyranteli Embonas [who-ip Latin]

    76. 2-naphthoic Acid, 4,4'-methylenebis(3-hydroxy-, Compd. With (e)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine (1:1)

    77. 4,4'-methylenebis(3-hydroxy-2-naphthoic) Acid, Compound With (e)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine (1:1)

    78. Ac-24204

    79. As-12185

    80. Bp166202

    81. Hy-12640

    82. Sbi-0051499.p003

    83. C07389

    84. D00486

    85. F21340

    86. 204p246

    87. A816013

    88. Sr-05000001708

    89. Q3489331

    90. Sr-05000001708-1

    91. Pyrantel Pamoate, Vetranal(tm), Analytical Standard

    92. (e)-1-methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6

    93. Pyrantel Embonate, European Pharmacopoeia (ep) Reference Standard

    94. Pyrantel Pamoate, United States Pharmacopeia (usp) Reference Standard

    95. Pyrimidine,1,4,5,6-tetrahydro-1-methyl-2-[(1e)-2-(2-thienyl)ethenyl]-

    96. (e)-1,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine 4,4'-methylenebis[3-hydroxy-2-naphthoate] (1:1)

    97. 2-naphthalenecarboxylic Acid,4'-methylenebis[3-hydroxy-, Compd. With (e)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]pyrimidine (1:1)

    98. 2-naphthoic Acid,4'-methylenebis[3-hydroxy-, Compd. With (e)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine (1:1)

    99. 4,4'-methanediylbis(3-hydroxynaphthalene-2-carboxylic Acid) - 1-methyl-2-[(e)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine (1:1)

    100. 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic Acid,1-methyl-2-[(e)-2-thiophen-2-ylethenyl]-5,6-dihydro-4h-pyrimidine

    101. Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-[2-(-2-thienyl)ethenyl-, (e)-, With 4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid (1:1)

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 594.7 g/mol
    Molecular Formula C34H30N2O6S
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count6
    Exact Mass594.18245785 g/mol
    Monoisotopic Mass594.18245785 g/mol
    Topological Polar Surface Area159 Ų
    Heavy Atom Count43
    Formal Charge0
    Complexity816
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antinematodal Agents

    Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice. (See all compounds classified as Antinematodal Agents.)

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    Megafine Pharma P Ltd

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    Orion Corp

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    PYRANTEL PAMOATE

    VMF Number : 5205

    Submission : 1988-02-24

    Status : Inactive

    Type : II

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    Submission : 1996-05-23

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    11-Jan-2021
    31-Aug-2024
    KGS
    overview
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