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Synopsis

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Chemistry

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Also known as: Pyrithioxin, 1098-97-1, Pyrithioxine, Bonifen, Encefabol, Pyridoxine disulfide
Molecular Formula
C16H20N2O4S2
Molecular Weight
368.5  g/mol
InChI Key
SIXLXDIJGIWWFU-UHFFFAOYSA-N
FDA UNII
AK5Q5FZH2R

Pyritinol
A neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
1 2D Structure

Pyritinol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol
2.1.2 InChI
InChI=1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3
2.1.3 InChI Key
SIXLXDIJGIWWFU-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=NC=C(C(=C1O)CO)CSSCC2=CN=C(C(=C2CO)O)C
2.2 Other Identifiers
2.2.1 UNII
AK5Q5FZH2R
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bonifen

2. Dipyridoxolyldisulfide

3. Encephabol

4. Enerbol

5. Hydrochloride, Pyritinol

6. Piriditol

7. Piritinol

8. Piritoxina

9. Pyridoxinedisulfide

10. Pyrithioxin

11. Pyrithioxine

12. Pyritinol Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. Pyrithioxin

2. 1098-97-1

3. Pyrithioxine

4. Bonifen

5. Encefabol

6. Pyridoxine Disulfide

7. Piritinol

8. Bonol

9. Epocan

10. Vitamin B6 Disulfide

11. Dipyridoxolyldisulfide

12. Biocefalin

13. Pyridoxine-5-disulfide

14. Pyrithioxine [jan]

15. Ak5q5fzh2r

16. Nsc-759229

17. 5,5'-(disulfanediylbis(methylene))bis(4-(hydroxymethyl)-2-methylpyridin-3-ol)

18. Pyrithioxine Hydrochloride

19. 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol

20. Pyritinol (inn)

21. 4-pyridinemethanol, 3,3'-[dithiobis(methylene)]bis[5-hydroxy-6-methyl-

22. Pyrithioxine (jan)

23. Pyritioxine

24. Pyritinol [inn]

25. Piritinolo [dcit]

26. Piritinolo

27. Pyritinolum

28. Piritinol [inn-spanish]

29. Pyritinolum [inn-latin]

30. 4-pyridinemethanol, 3,3'-(dithiobis(methylene))bis(5-hydroxy-6-methyl-

31. 5,5'-[dithiobis(methylene)]bis[4-(hydroxymethyl)-2-methylpyridin-3-ol]

32. Pyritinol [inn:ban:dcf]

33. Ncgc00166140-01

34. Einecs 214-150-1

35. Unii-ak5q5fzh2r

36. 5,5'-(disulfanediyldimethanediyl)bis[4-(hydroxymethyl)-2-methylpyridin-3-ol]

37. Pyritinol [mi]

38. Pyritinol, Pyrithioxin

39. 3,3'-(dithiobis(methylene))bis(5-hydroxy-6-methyl-4-pyridinemethanol)

40. 4-pyridinemethanol, 3,3'-(dithiodimethylene)bis(5-hydroxy-6-methyl-

41. Pyritinol [who-dd]

42. Mls004712044

43. Schembl150551

44. Chembl488093

45. Pyrithioxin, Analytical Standard

46. Dtxsid3048362

47. Chebi:135554

48. Hms3264m15

49. Hms3886m13

50. Pharmakon1600-01505762

51. Hy-b0910

52. 3,3'-(dithiodimethylene)bis(5-hydroxy-6-methyl-4-pyridinemethanol)

53. Bbl028281

54. Mfcd00151477

55. Nsc759229

56. S5141

57. Stk801801

58. Zinc37866091

59. 5,5'-disulfanediylbis(methylene)bis(4-(hydroxymethyl)-2-methylpyridin-3-ol)

60. Akos005066380

61. Ccg-213980

62. Db13084

63. Nsc 759229

64. 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-pyridin-3-ol

65. Ac-12193

66. As-13595

67. Smr001550535

68. Sbi-0207045.p001

69. Db-050233

70. Ft-0674240

71. P2250

72. C71346

73. D02160

74. Ab00375835_02

75. A802103

76. Q416361

77. Sr-01000872772

78. Sr-01000872772-1

79. W-108702

80. Brd-k82181219-001-01-9

81. Bis(4-hydroxymethyl-5-hydroxy-6-methyl-3-pyridylmethyl)disulfide

82. 5,5'-(dithiodimethylene) Bis[3-hydroxy-4-hydroxymethyl-2-methylpyridine]

83. 5,5'-(dithiodimethylene)bis[3-hydroxy-4-hydroxymethyl-2-methylpyridine]

84. 5,5'-[disulfanediylbis(methylene)]bis[4-(hydroxymethyl)-2-methyl-3-pyridinol]

85. 4-(hydroxymethyl)-5-[[[4-(hydroxymethyl)-6-methyl-5-oxidanyl-pyridin-3-yl]methyldisulfanyl]methyl]-2-methyl-pyridin-3-ol

86. 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridinyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-3-pyridinol

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 368.5 g/mol
Molecular Formula C16H20N2O4S2
XLogP31.2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass368.08644947 g/mol
Monoisotopic Mass368.08644947 g/mol
Topological Polar Surface Area157 Ų
Heavy Atom Count24
Formal Charge0
Complexity346
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

N - Nervous system

N06 - Psychoanaleptics

N06B - Psychostimulants, agents used for adhd and nootropics

N06BX - Other psychostimulants and nootropics

N06BX02 - Pyritinol


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ABOUT THIS PAGE

Pyritinol Manufacturers

A Pyritinol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pyritinol, including repackagers and relabelers. The FDA regulates Pyritinol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pyritinol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Pyritinol manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Pyritinol Suppliers

A Pyritinol supplier is an individual or a company that provides Pyritinol active pharmaceutical ingredient (API) or Pyritinol finished formulations upon request. The Pyritinol suppliers may include Pyritinol API manufacturers, exporters, distributors and traders.

click here to find a list of Pyritinol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Pyritinol GMP

Pyritinol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pyritinol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pyritinol GMP manufacturer or Pyritinol GMP API supplier for your needs.

Pyritinol CoA

A Pyritinol CoA (Certificate of Analysis) is a formal document that attests to Pyritinol's compliance with Pyritinol specifications and serves as a tool for batch-level quality control.

Pyritinol CoA mostly includes findings from lab analyses of a specific batch. For each Pyritinol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pyritinol may be tested according to a variety of international standards, such as European Pharmacopoeia (Pyritinol EP), Pyritinol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pyritinol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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