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Chemistry

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Also known as: Pyrrolnitrine, 1018-71-9, Pyroace, 3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole, Pirrolnitrina, Pyrrolnitrinum
Molecular Formula
C10H6Cl2N2O2
Molecular Weight
257.07  g/mol
InChI Key
QJBZDBLBQWFTPZ-UHFFFAOYSA-N
FDA UNII
N0P24B6EDQ

Pyrrolnitrin
3-Chloro-4-(3-chloro-2-nitrophenyl)pyrrole. Antifungal antibiotic isolated from Pseudomonas pyrrocinia. It is effective mainly against Trichophyton, Microsporium, Epidermophyton, and Penicillium.
1 2D Structure

Pyrrolnitrin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-chloro-4-(3-chloro-2-nitrophenyl)-1H-pyrrole
2.1.2 InChI
InChI=1S/C10H6Cl2N2O2/c11-8-3-1-2-6(10(8)14(15)16)7-4-13-5-9(7)12/h1-5,13H
2.1.3 InChI Key
QJBZDBLBQWFTPZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC(=C(C(=C1)Cl)[N+](=O)[O-])C2=CNC=C2Cl
2.2 Other Identifiers
2.2.1 UNII
N0P24B6EDQ
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Pyrrolnitrine

2. 1018-71-9

3. Pyroace

4. 3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole

5. Pirrolnitrina

6. Pyrrolnitrinum

7. Nsc-107654

8. Fr 005759

9. Pyrollnitrin

10. 3-chloro-4-(2'-nitro-3'-chlorophenyl)pyrrole

11. 3-chloro-4-(3-chloro-2-nitrophenyl)-1h-pyrrole

12. 1h-pyrrole, 3-chloro-4-(3-chloro-2-nitrophenyl)-

13. Nsc 107654

14. Pyrrole, 3-chloro-4-(3-chloro-2-nitrophenyl)-

15. Nsc107654

16. N0p24b6edq

17. Chebi:32079

18. 3-chloro-4-(3-chloro-2-nitro-phenyl)-1h-pyrrole

19. Ncgc00181136-01

20. 3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole;3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole

21. Pyrrolnitrine [inn-french]

22. Pyrrolnitrinum [inn-latin]

23. Pirrolnitrina [inn-spanish]

24. Pyrrolnitrin [usan:inn:jan]

25. Einecs 213-812-7

26. Unii-n0p24b6edq

27. Brn 1287646

28. Pirrolnitrin

29. 3-chloro-4-(3'-chloro-2'-nitrophenyl)pyrrole

30. Pyrrolnitrine;pyroace

31. Pyrrolnitrin [mi]

32. Pyrrolnitrin [inn]

33. Pyrrolnitrin [jan]

34. Pyrrolnitrin [usan]

35. Dsstox_cid_26867

36. Dsstox_rid_81974

37. Dsstox_gsid_46867

38. Schembl73199

39. Pyrrolnitrin [mart.]

40. 5-20-07-00373 (beilstein Handbook Reference)

41. Chembl97972

42. Pyrrolnitrin [who-dd]

43. Zinc2012

44. Dtxsid9046867

45. Pyrrolnitrin (jp17/usan/inn)

46. Wln: T5mj Cg Dr Cg Bnw

47. Bcp33872

48. Tox21_112743

49. Nsc637277

50. Db13603

51. Nsc-637277

52. Ac-32022

53. Cas-1018-71-9

54. Hy-133704

55. Cs-0129743

56. Ft-0701269

57. Ft-0701270

58. D01094

59. Q371817

60. Pyrrolnitrin From Pseudomonas Cepacia, >=98% (hplc), Solid

61. Pyrrolnitrin;3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole_hcd40

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 257.07 g/mol
Molecular Formula C10H6Cl2N2O2
XLogP34.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass255.9806328 g/mol
Monoisotopic Mass255.9806328 g/mol
Topological Polar Surface Area61.6 Ų
Heavy Atom Count16
Formal Charge0
Complexity272
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antifungal Agents

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)


4.2 ATC Code

D - Dermatologicals

D01 - Antifungals for dermatological use

D01A - Antifungals for topical use

D01AA - Antibiotics

D01AA07 - Pyrrolnitrin


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Looking for 1018-71-9 / Pyrrolnitrin API manufacturers, exporters & distributors?

Pyrrolnitrin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Pyrrolnitrin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Pyrrolnitrin manufacturer or Pyrrolnitrin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Pyrrolnitrin manufacturer or Pyrrolnitrin supplier.

PharmaCompass also assists you with knowing the Pyrrolnitrin API Price utilized in the formulation of products. Pyrrolnitrin API Price is not always fixed or binding as the Pyrrolnitrin Price is obtained through a variety of data sources. The Pyrrolnitrin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Pyrrolnitrin

Synonyms

Pyrrolnitrine, 1018-71-9, Pyroace, 3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole, Pirrolnitrina, Pyrrolnitrinum

Cas Number

1018-71-9

Unique Ingredient Identifier (UNII)

N0P24B6EDQ

About Pyrrolnitrin

3-Chloro-4-(3-chloro-2-nitrophenyl)pyrrole. Antifungal antibiotic isolated from Pseudomonas pyrrocinia. It is effective mainly against Trichophyton, Microsporium, Epidermophyton, and Penicillium.

Pyrrolnitrin Manufacturers

A Pyrrolnitrin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pyrrolnitrin, including repackagers and relabelers. The FDA regulates Pyrrolnitrin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pyrrolnitrin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Pyrrolnitrin Suppliers

A Pyrrolnitrin supplier is an individual or a company that provides Pyrrolnitrin active pharmaceutical ingredient (API) or Pyrrolnitrin finished formulations upon request. The Pyrrolnitrin suppliers may include Pyrrolnitrin API manufacturers, exporters, distributors and traders.

Pyrrolnitrin GMP

Pyrrolnitrin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pyrrolnitrin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pyrrolnitrin GMP manufacturer or Pyrrolnitrin GMP API supplier for your needs.

Pyrrolnitrin CoA

A Pyrrolnitrin CoA (Certificate of Analysis) is a formal document that attests to Pyrrolnitrin's compliance with Pyrrolnitrin specifications and serves as a tool for batch-level quality control.

Pyrrolnitrin CoA mostly includes findings from lab analyses of a specific batch. For each Pyrrolnitrin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pyrrolnitrin may be tested according to a variety of international standards, such as European Pharmacopoeia (Pyrrolnitrin EP), Pyrrolnitrin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pyrrolnitrin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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