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Chemistry

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Also known as: 10447-39-9, Quifenadine [inn], 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol, 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol, W9a18rj49b, Fenkarol
Molecular Formula
C20H23NO
Molecular Weight
293.4  g/mol
InChI Key
PZMAHNDJABQWGS-UHFFFAOYSA-N
FDA UNII
W9A18RJ49B

Quifenadine
1 2D Structure

Quifenadine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol
2.1.2 InChI
InChI=1S/C20H23NO/c22-20(17-7-3-1-4-8-17,18-9-5-2-6-10-18)19-15-21-13-11-16(19)12-14-21/h1-10,16,19,22H,11-15H2
2.1.3 InChI Key
PZMAHNDJABQWGS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN2CCC1C(C2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O
2.2 Other Identifiers
2.2.1 UNII
W9A18RJ49B
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Fenatin

2. Fencarol

3. Phencarol

4. Quifenadine Hydrobromide, (+-)-isomer

5. Quifenadine Hydrochloride

6. Quinuclidinyl-3-diphenylcarbinol

2.3.2 Depositor-Supplied Synonyms

1. 10447-39-9

2. Quifenadine [inn]

3. 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol

4. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol

5. W9a18rj49b

6. Fenkarol

7. Quifenadine (inn)

8. (3-quinuclidinyl)diphenyl Carbinol Hydrochloride

9. Ncgc00160492-01

10. .alpha.,.alpha.-diphenyl-3-quinuclidinemethanol

11. {1-azabicyclo[2.2.2]octan-3-yl}diphenylmethanol

12. Quifenadino

13. Quifenadinum

14. Quifenadinum [inn-latin]

15. Quifenadino [inn-spanish]

16. Benzhydrol, Alpha-(3-quinuclidinyl)-

17. Brn 1542055

18. Unii-w9a18rj49b

19. Alpha,alpha-diphenyl-3-quinuclidinemethanol

20. Alpha,alpha-diphenyl-3-chinuclidinylmethanol

21. 1-azabicyclo[2.2.2]octane-3-methanol,a,a-diphenyl-

22. 1-azabicyclo(2.2.2)octane-3-methanol, Alpha,alpha-diphenyl-

23. 3-quinuclidinemethanol, Alpha,alpha-diphenyl-

24. Fencarol [as Hydrochloride]

25. Dsstox_cid_26187

26. Dsstox_rid_81418

27. Dsstox_gsid_46187

28. Oprea1_250552

29. Phencarol [as Hydrochloride]

30. Phencarol; Fenatin; Fencarol

31. Quifenadine [who-dd]

32. Mls006011470

33. Schembl1813124

34. Chembl1187694

35. Dtxsid6046187

36. Schembl15292380

37. Chebi:134746

38. Bcp21301

39. Tox21_111852

40. Bbl022956

41. Mfcd01684913

42. Stk697937

43. Akos001668833

44. Db13713

45. Benzhydrol, .alpha.-(3-quinuclidinyl)-

46. Ncgc00160492-02

47. Smr002499074

48. Vs-07290

49. Cas-10447-39-9

50. D10230

51. Ab00637982-07

52. 3-quinuclidinemethanol, .alpha.,.alpha.-diphenyl-

53. Ag-205/05218021

54. Q4497981

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 293.4 g/mol
Molecular Formula C20H23NO
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass293.177964357 g/mol
Monoisotopic Mass293.177964357 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count22
Formal Charge0
Complexity344
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine Antagonists

Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)


4.2 ATC Code

R - Respiratory system

R06 - Antihistamines for systemic use

R06A - Antihistamines for systemic use

R06AX - Other antihistamines for systemic use

R06AX31 - Quifenadine


Market Place

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ABOUT THIS PAGE

Quifenadine Manufacturers

A Quifenadine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Quifenadine, including repackagers and relabelers. The FDA regulates Quifenadine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Quifenadine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Quifenadine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Quifenadine Suppliers

A Quifenadine supplier is an individual or a company that provides Quifenadine active pharmaceutical ingredient (API) or Quifenadine finished formulations upon request. The Quifenadine suppliers may include Quifenadine API manufacturers, exporters, distributors and traders.

click here to find a list of Quifenadine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Quifenadine GMP

Quifenadine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Quifenadine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Quifenadine GMP manufacturer or Quifenadine GMP API supplier for your needs.

Quifenadine CoA

A Quifenadine CoA (Certificate of Analysis) is a formal document that attests to Quifenadine's compliance with Quifenadine specifications and serves as a tool for batch-level quality control.

Quifenadine CoA mostly includes findings from lab analyses of a specific batch. For each Quifenadine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Quifenadine may be tested according to a variety of international standards, such as European Pharmacopoeia (Quifenadine EP), Quifenadine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Quifenadine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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