Find R-Tofisopam manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: R-tofisopam, Ez15i5d6c1, 82059-50-5, (5r)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine, (+)-(5r)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine, Dextofisopam [usan]
Molecular Formula
C22H26N2O4
Molecular Weight
382.5  g/mol
InChI Key
RUJBDQSFYCKFAA-HNNXBMFYSA-N
FDA UNII
EZ15I5D6C1

R-Tofisopam
1 2D Structure

R-Tofisopam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(5R)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
2.1.2 InChI
InChI=1S/C22H26N2O4/c1-7-15-13(2)23-24-22(14-8-9-18(25-3)19(10-14)26-4)17-12-21(28-6)20(27-5)11-16(15)17/h8-12,15H,7H2,1-6H3/t15-/m0/s1
2.1.3 InChI Key
RUJBDQSFYCKFAA-HNNXBMFYSA-N
2.1.4 Canonical SMILES
CCC1C(=NN=C(C2=CC(=C(C=C12)OC)OC)C3=CC(=C(C=C3)OC)OC)C
2.1.5 Isomeric SMILES
CC[C@H]1C(=NN=C(C2=CC(=C(C=C12)OC)OC)C3=CC(=C(C=C3)OC)OC)C
2.2 Other Identifiers
2.2.1 UNII
EZ15I5D6C1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine

2. Egyt-341

3. Grandaxin

4. Levotofisopam

5. Tofisopam

6. Tofizopam

2.3.2 Depositor-Supplied Synonyms

1. R-tofisopam

2. Ez15i5d6c1

3. 82059-50-5

4. (5r)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine

5. (+)-(5r)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine

6. Dextofisopam [usan]

7. Dextofisopam (usan/inn)

8. Dextofisopam [usan:inn]

9. Unii-ez15i5d6c1

10. Dextofisopam [inn]

11. Schembl236796

12. Schembl8086913

13. Chembl2107331

14. Dtxsid00231554

15. Zinc608106

16. Db06582

17. D03737

18. Q27277442

19. (5r)-1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine

20. 5h-2,3-benzodiazepine, 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-, (5r)-

21. 5h-2,3-benzodiazepine, 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl, (5r)

22. Jpu

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 382.5 g/mol
Molecular Formula C22H26N2O4
XLogP33.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass382.18925731 g/mol
Monoisotopic Mass382.18925731 g/mol
Topological Polar Surface Area61.6 Ų
Heavy Atom Count28
Formal Charge0
Complexity579
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Investigated for use/treatment in irritable bowel syndrome (IBS).


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)


ABOUT THIS PAGE

Looking for 82059-50-5 / R-Tofisopam API manufacturers, exporters & distributors?

R-Tofisopam manufacturers, exporters & distributors 1

23

PharmaCompass offers a list of R-Tofisopam API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right R-Tofisopam manufacturer or R-Tofisopam supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred R-Tofisopam manufacturer or R-Tofisopam supplier.

PharmaCompass also assists you with knowing the R-Tofisopam API Price utilized in the formulation of products. R-Tofisopam API Price is not always fixed or binding as the R-Tofisopam Price is obtained through a variety of data sources. The R-Tofisopam Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

R-Tofisopam

Synonyms

Ez15i5d6c1, 82059-50-5, (5r)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine, (+)-(5r)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine, Dextofisopam [usan], Dextofisopam (usan/inn)

Cas Number

82059-50-5

Unique Ingredient Identifier (UNII)

EZ15I5D6C1

R-Tofisopam Manufacturers

A R-Tofisopam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of R-Tofisopam, including repackagers and relabelers. The FDA regulates R-Tofisopam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. R-Tofisopam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

R-Tofisopam Suppliers

A R-Tofisopam supplier is an individual or a company that provides R-Tofisopam active pharmaceutical ingredient (API) or R-Tofisopam finished formulations upon request. The R-Tofisopam suppliers may include R-Tofisopam API manufacturers, exporters, distributors and traders.

R-Tofisopam GMP

R-Tofisopam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of R-Tofisopam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right R-Tofisopam GMP manufacturer or R-Tofisopam GMP API supplier for your needs.

R-Tofisopam CoA

A R-Tofisopam CoA (Certificate of Analysis) is a formal document that attests to R-Tofisopam's compliance with R-Tofisopam specifications and serves as a tool for batch-level quality control.

R-Tofisopam CoA mostly includes findings from lab analyses of a specific batch. For each R-Tofisopam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

R-Tofisopam may be tested according to a variety of international standards, such as European Pharmacopoeia (R-Tofisopam EP), R-Tofisopam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (R-Tofisopam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty