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Chemistry

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Also known as: 496054-87-6, Rgh-896, Radiprodil [inn], 5xgc17zkuf, Chembl182066, 2-(4-(4-fluorobenzyl)piperidin-1-yl)-2-oxo-n-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)acetamide
Molecular Formula
C21H20FN3O4
Molecular Weight
397.4  g/mol
InChI Key
GKGRZLGAQZPEHO-UHFFFAOYSA-N
FDA UNII
5XGC17ZKUF

Radiprodil
Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain.
1 2D Structure

Radiprodil

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]-2-oxo-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide
2.1.2 InChI
InChI=1S/C21H20FN3O4/c22-15-3-1-13(2-4-15)11-14-7-9-25(10-8-14)20(27)19(26)23-16-5-6-17-18(12-16)29-21(28)24-17/h1-6,12,14H,7-11H2,(H,23,26)(H,24,28)
2.1.3 InChI Key
GKGRZLGAQZPEHO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN(CCC1CC2=CC=C(C=C2)F)C(=O)C(=O)NC3=CC4=C(C=C3)NC(=O)O4
2.2 Other Identifiers
2.2.1 UNII
5XGC17ZKUF
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(4-(4-fluoro-benzyl)-piperidin-1-yl)-2-oxo-n-(2-oxo-2,3-dihydro-benzooxazol-6-yl)-acetamide

2.3.2 Depositor-Supplied Synonyms

1. 496054-87-6

2. Rgh-896

3. Radiprodil [inn]

4. 5xgc17zkuf

5. Chembl182066

6. 2-(4-(4-fluorobenzyl)piperidin-1-yl)-2-oxo-n-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)acetamide

7. 2-(4-((4-fluorophenyl)methyl)piperidin-1-yl)-2-oxo-n-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)acetamide

8. 2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-oxo-n-(2-oxo-2,3-dihydro-benzooxazol-6-yl)-acetamide

9. Unii-5xgc17zkuf

10. Radiprodil (rgh-896)

11. Radiprodil [who-dd]

12. Schembl99256

13. Dtxsid80964297

14. Rgh 896

15. Bcp30852

16. Wua05487

17. Bdbm50149684

18. S6644

19. Zinc28363953

20. Db12260

21. 2-[4-(4-fluorobenzyl)piperidin-1-yl]-2-oxo-n-(2-oxo-2,3-dihydrobenzoxazol-6-yl)acetamide

22. Ncgc00386549-01

23. 2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]-2-oxo-n-(2-oxo-3h-1,3-benzoxazol-6-yl)acetamide

24. 2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}-n-(2-hydroxy-1,3-benzoxazol-6-yl)-2-oxoacetamide

25. Bs-16896

26. Hy-14777

27. Cs-0003554

28. Rgh-896; Rgh896; Rgh 896

29. N16882

30. Q27263011

31. 1-piperidineacetamide, N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-alpha-oxo-

32. 2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-oxo-n-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide

33. 2-[4-(4-fluorobenzyl)-piperidin-1-yl]-2-oxo-n-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide

34. N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-alpha-oxo-1-piperidineacetamide

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 397.4 g/mol
Molecular Formula C21H20FN3O4
XLogP33
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area87.7
Heavy Atom Count29
Formal Charge0
Complexity629
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Radiprodil Manufacturers

A Radiprodil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Radiprodil, including repackagers and relabelers. The FDA regulates Radiprodil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Radiprodil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Radiprodil Suppliers

A Radiprodil supplier is an individual or a company that provides Radiprodil active pharmaceutical ingredient (API) or Radiprodil finished formulations upon request. The Radiprodil suppliers may include Radiprodil API manufacturers, exporters, distributors and traders.

Radiprodil GMP

Radiprodil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Radiprodil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Radiprodil GMP manufacturer or Radiprodil GMP API supplier for your needs.

Radiprodil CoA

A Radiprodil CoA (Certificate of Analysis) is a formal document that attests to Radiprodil's compliance with Radiprodil specifications and serves as a tool for batch-level quality control.

Radiprodil CoA mostly includes findings from lab analyses of a specific batch. For each Radiprodil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Radiprodil may be tested according to a variety of international standards, such as European Pharmacopoeia (Radiprodil EP), Radiprodil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Radiprodil USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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