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Chemistry

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Also known as: 22662-39-1, Disalan, Ranide, Flukanide, Bovanide, Duofas
Molecular Formula
C19H11Cl2I2NO3
Molecular Weight
626.0  g/mol
InChI Key
NEMNPWINWMHUMR-UHFFFAOYSA-N
FDA UNII
22F4FLA7DH

Rafoxanide
Veterinary anthelmintic for grazing animals; used to treat fluke, hookworm and other infestations.
1 2D Structure

Rafoxanide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
2.1.2 InChI
InChI=1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)
2.1.3 InChI Key
NEMNPWINWMHUMR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1OC2=C(C=C(C=C2)NC(=O)C3=C(C(=CC(=C3)I)I)O)Cl)Cl
2.2 Other Identifiers
2.2.1 UNII
22F4FLA7DH
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Disalan

2. Flukanide

3. Mk 990

4. Rafoxanid

5. Ranide

2.3.2 Depositor-Supplied Synonyms

1. 22662-39-1

2. Disalan

3. Ranide

4. Flukanide

5. Bovanide

6. Duofas

7. Ranide, Veterinary

8. 3'-chloro-4'-(4-chlorophenoxy)-3,5-diiodosalicylanilide

9. Mk-990

10. N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide

11. 3'-chloro-4'-(p-chlorophenoxy)-3,5-diiodosalicylanilide

12. Nsc-355278

13. N-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodobenzamide

14. 22f4fla7dh

15. Benzamide, N-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo-

16. Salicylanilide, 3'-chloro-4'-(p-chlorophenoxy)-3,5-diiodo-

17. Nsc355278

18. Ncgc00160556-01

19. Dsstox_cid_26227

20. Dsstox_rid_81454

21. Dsstox_gsid_46227

22. Rafoxanida

23. Rafoxanidum

24. Rafoxanidum [inn-latin]

25. Rafoxanida [inn-spanish]

26. Nsc 355278

27. Cas-22662-39-1

28. Einecs 245-148-9

29. Unii-22f4fla7dh

30. Brn 2228187

31. Rafoxanide [usan:inn:ban]

32. Ai3-29020

33. Rafoxanide Vetranal

34. 3'-chlor-4'-(4-chlorphenoxy)-3,5-diiodsalicylanilid

35. Rafoxanide [mi]

36. Rafoxanide [inn]

37. Rafoxanide (usan/inn)

38. Salicylanilide,5-diiodo-

39. Rafoxanide [usan]

40. Rafoxanide [mart.]

41. Mls001240273

42. Schembl118031

43. Chembl287542

44. Dtxsid5046227

45. Hms2233m19

46. Bcp15963

47. N-(3-chloro-4-(4-chlorophenoxy)

48. Zinc4181896

49. Tox21_111896

50. Bdbm50022832

51. Mfcd00682899

52. Stk377482

53. Akos003631075

54. N-[3-chloro-4-(4-chloro-phenoxy)-phenyl]-2-hydroxy-3,5-diiodo-benzamide

55. N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-benzamide

56. Rafoxanide 100 Microg/ml In Methanol

57. Tox21_111896_1

58. Ccg-270276

59. Cs-3979

60. Ks-1309

61. Phenyl)-2-hydroxy-3,5-diiodobenzamide

62. Wln: Qr Bi Di Fvmr Cg Dor Dg

63. Ncgc00160556-02

64. Ac-20061

65. Hy-17598

66. Smr000768692

67. Db-045962

68. Ft-0630489

69. R0108

70. S5093

71. Rafoxanide, Pestanal(r), Analytical Standard

72. C74169

73. D05693

74. 662r391

75. J-014804

76. Q12048733

77. 3'-chloro-4'-(p-chlorophenoxy)-3, 5-diiodosalicylanilide

78. 3,5-diiodo-3'-chloro-4'-(p-chlorophenoxy)-salicylanilide

79. 3-chloro-4-(4-chlorophenoxy)-3,5-diiodosalicylanilide

80. Benzamide, {n-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,} 5-diiodo-

81. Benzamide, N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo- [

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 626.0 g/mol
Molecular Formula C19H11Cl2I2NO3
XLogP37
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass624.82054 g/mol
Monoisotopic Mass624.82054 g/mol
Topological Polar Surface Area58.6 Ų
Heavy Atom Count27
Formal Charge0
Complexity507
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antinematodal Agents

Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice. (See all compounds classified as Antinematodal Agents.)


Antiplatyhelmintic Agents

Agents used to treat cestode, trematode, or other flatworm infestations in man or animals. (See all compounds classified as Antiplatyhelmintic Agents.)


API Reference Price

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02-Jan-2021
29-Oct-2024
KGS
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