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Ramatroban

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ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 Listed Suppliers

1 API Suppliers
1 Listed Suppliers

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 116649-85-5, Baynas, Bay u3405, Bay u 3405, Bay-u-3405, Bay-u 3405

Molecular Formula

C₂₁H₂₁FN₂O₄S

Molecular Weight

416.5 g/mol

InChI Key

LDXDSHIEDAPSSA-OAHLLOKOSA-N

FDA UNII

P1ALI72U6C

Ramatroban has been used in trials studying the treatment of Asthma.

1 2D Structure

Ramatroban

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid

2.1.2 InChI

InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1

2.1.3 InChI Key

LDXDSHIEDAPSSA-OAHLLOKOSA-N

2.1.4 Canonical SMILES

C1CC2=C(CC1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O

2.1.5 Isomeric SMILES

C1CC2=C(C[C@@H]1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O

2.2 Other Identifiers

2.2.1 UNII

P1ALI72U6C

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9-carbazole Propanoic Acid

2. Bay U 3405

3. Bay U 3406

4. Bay U-3405

5. Bay U3405

2.3.2 Depositor-Supplied Synonyms

1. 116649-85-5

2. Baynas

3. Bay U3405

4. Bay U 3405

5. Bay-u-3405

6. Bay-u 3405

7. 3-[(3r)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic Acid

8. (+)-(3r)-3-(p-fluorobenzenesulfonamido)-1,2,3,4-tetrahydrocarbazole-9-propionic Acid

9. P1ali72u6c

10. (r)-3-(3-(4-fluorophenylsulfonamido)-3,4-dihydro-1h-carbazol-9(2h)-yl)propanoic Acid

11. 9h-carbazole-9-propanoic Acid, 3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-, (3r)-

12. En-137774

13. Chembl361812

14. Ncgc00167519-01

15. En 137774

16. Bay U 3406

17. Bay U-3405

18. (3r)-3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9h-carbazole-9-propanoic Acid

19. Dsstox_cid_26685

20. Dsstox_rid_81819

21. Dsstox_gsid_46685

22. [3h]ramatroban

23. [3h]baynas

24. Baynas (tn)

25. Cas-116649-85-5

26. Ramatroban (jan/inn)

27. Ramatroban [inn:ban]

28. Unii-p1ali72u6c

29. 3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9-carbazole Propanoic Acid

30. [3h]bay U 3405

31. [3h]bay U3405

32. 3r-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9h-carbazole-9-propanoic Acid

33. (3r)-3-(((4-fluorophenyl)sulfonyl)amino)-1,2,3,4-tetrahydro-9h-carbazole-9-propanoic Acid

34. 9h-carbazole-9-propanoic Acid, 3-(((4-fluorophenyl)sulfonyl)amino)-1,2,3,4-tetrahydro-, (3r)-

35. Mfcd00887606

36. Ramatroban [mi]

37. Ramatroban [inn]

38. Ramatroban [jan]

39. Ramatroban [mart.]

40. 9h-carbazole-9-propanoic Acid, 3-(((4-fluorophenyl)sulfonyl)amino)-1,2,3,4-tetrahydro-, (r)-

41. Ramatroban [who-dd]

42. Ramatroban (bay U3405)

43. Schembl29030

44. Mls006010637

45. Gtpl1910

46. Gtpl1911

47. Dtxsid1046685

48. Chebi:32087

49. Hms3648e21

50. Bay U3405;bay-u3405

51. Ex-a4208

52. Hy-b0745

53. Zinc3798772

54. Tox21_112516

55. Ac-719

56. Bdbm50161746

57. S5286

58. Akos015966619

59. Ramatroban, >=98% (hplc), Solid

60. Tox21_112516_1

61. Ccg-268842

62. Db13036

63. Ks-1310

64. Ncgc00167519-02

65. Ncgc00167519-04

66. Ncgc00167519-07

67. Smr002530322

68. R0144

69. D01128

70. 649f855

71. A803658

72. Sr-01000883932

73. Sr-01000946208

74. J-003466

75. Sr-01000883932-1

76. Sr-01000946208-1

77. Q10357327

78. (r)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic Acid

79. (r)-3-(3-(4-fluorophenylsulfonamido)-3,4-dihydro-1h-carbazol-9(2h)-yl)propanoicacid

80. [(4-fluorophenyl)sulfonylamino] 3-(1,2,3,4-tetrahydrocarbazol-9-yl)propanoate

81. 3(r)-[[(4-fluoro-phenyl) Sulfonyl]amino]-1,2,3,4-tetrahydro-9h-carbazole-9-propanoic Acid

82. 3-[(r)-3-(4-fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic Acid

83. A8x

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₁FN₂O₄S
Molecular Weight	416.5 g/mol
XLogP3	2.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	416.12060649 g/mol
Monoisotopic Mass	416.12060649 g/mol
Topological Polar Surface Area	96.8 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	689
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Platelet Aggregation Inhibitors

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)

API SUPPLIERS

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Listed Suppliers

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Drugs in Development

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ABOUT THIS PAGE

Ramatroban Manufacturers

A Ramatroban manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ramatroban, including repackagers and relabelers. The FDA regulates Ramatroban manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ramatroban API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ramatroban manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ramatroban Suppliers

A Ramatroban supplier is an individual or a company that provides Ramatroban active pharmaceutical ingredient (API) or Ramatroban finished formulations upon request. The Ramatroban suppliers may include Ramatroban API manufacturers, exporters, distributors and traders.

click here to find a list of Ramatroban suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ramatroban GMP

Ramatroban Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ramatroban GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ramatroban GMP manufacturer or Ramatroban GMP API supplier for your needs.

Ramatroban CoA

A Ramatroban CoA (Certificate of Analysis) is a formal document that attests to Ramatroban's compliance with Ramatroban specifications and serves as a tool for batch-level quality control.

Ramatroban CoA mostly includes findings from lab analyses of a specific batch. For each Ramatroban CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ramatroban may be tested according to a variety of international standards, such as European Pharmacopoeia (Ramatroban EP), Ramatroban JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ramatroban USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.