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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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JDMF

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NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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FDF

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Canada

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USP

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Chemistry

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Also known as: Ravidasvir [usan], 1242087-93-9, Ppi-668 free base, Al3g001bi8, Bi 238630, Bi-238630
Molecular Formula
C42H50N8O6
Molecular Weight
762.9  g/mol
InChI Key
LCHMHYPWGWYXEL-ZYADHFCISA-N
FDA UNII
AL3G001BI8

Ravidasvir
Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).
1 2D Structure

Ravidasvir

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl N-[(2S)-1-[(2S)-2-[5-[6-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-3H-benzimidazol-5-yl]naphthalen-2-yl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
2.1.2 InChI
InChI=1S/C42H50N8O6/c1-23(2)35(47-41(53)55-5)39(51)49-17-7-9-33(49)37-43-22-32(46-37)29-14-13-25-19-26(11-12-27(25)20-29)28-15-16-30-31(21-28)45-38(44-30)34-10-8-18-50(34)40(52)36(24(3)4)48-42(54)56-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,43,46)(H,44,45)(H,47,53)(H,48,54)/t33-,34-,35-,36-/m0/s1
2.1.3 InChI Key
LCHMHYPWGWYXEL-ZYADHFCISA-N
2.1.4 Canonical SMILES
CC(C)C(C(=O)N1CCCC1C2=NC3=C(N2)C=C(C=C3)C4=CC5=C(C=C4)C=C(C=C5)C6=CN=C(N6)C7CCCN7C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC
2.1.5 Isomeric SMILES
CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC3=C(N2)C=C(C=C3)C4=CC5=C(C=C4)C=C(C=C5)C6=CN=C(N6)[C@@H]7CCCN7C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
2.2 Other Identifiers
2.2.1 UNII
AL3G001BI8
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ppi-668

2.3.2 Depositor-Supplied Synonyms

1. Ravidasvir [usan]

2. 1242087-93-9

3. Ppi-668 Free Base

4. Al3g001bi8

5. Bi 238630

6. Bi-238630

7. Carbamic Acid, N-((1s)-1-(((2s)-2-(5-(6-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methyl-1-oxobutyl)-2-pyrrolidinyl)-1h-benzimidazol-6-yl)-2-naphthalenyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)-, Methyl Ester

8. Methyl N-((1s)-1-(((2s)-2-(5-(6-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3- Methylbutanoyl)pyrrolidin-2-yl)-1h-imidazol-4-yl)naphthalen-2-yl)-1h-benzimidazol-2-yl)pyrrolidin-1-yl)carbonyl)-2-methylpropyl)carbamate

9. Methyl N-[(2s)-1-[(2s)-2-[5-[6-[2-[(2s)-1-[(2s)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-3h-benzimidazol-5-yl]naphthalen-2-yl]-1h-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

10. Carbamic Acid, N-[(1s)-1-[[(2s)-2-[5-[6-[2-[(2s)-1-[(2s)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1h-benzimidazol-6-yl]-2-naphthalenyl]-1h-imidazol-2-yl]-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-, Methyl Ester

11. Unii-al3g001bi8

12. Ravidasvir Free Base

13. Bl-238630

14. Ravidasvir [inn]

15. Ravidasvir [who-dd]

16. Schembl7603463

17. Chembl3121849

18. Schembl12075676

19. Bdbm243443

20. Dtxsid401335997

21. Us9427428, 3

22. Q27273972

23. Methyl ((1s)-1-(((2s)-2-(4-(6-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-benzimidazol-5-yl)-2-naphthyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate

24. Methyl N-[(1s)-1-[[(2s)-2-[5-[6-[2-[(2s)-1-[(2s)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1h-benzimidazol-6-yl]-2-naphthalenyl]-1h-imidazol-2-yl]-1-pyrrolidinyl]carbonyl]-2-methylpropyl]carbamate

25. Methyl((1s)-1-(((2s)-2-(4-(6-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-benzimidazol-5-yl)-2-naphthyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate

26. Methyl((s)-1-((s)-2-(5-(6-(2((s)-1-((methoxycarbonyl)-l-valyl)pyrrolidin-2-yl)-1h-imidazol-4-yl)naphthalen-2-yl)-1h-benzo[d]imidazol-2-yl) Pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate

27. Methyln-[(1s)-1-[[(2s)-2-[5-[6-[2-[(2s)-1-[(2s)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1h-benzimidazol-6-yl]-2-naphthalenyl]-1h-imidazol-2-yl]-1-pyrrolidinyl]carbonyl]-2-methylpropyl]carbamate

2.4 Create Date
2011-06-06
3 Chemical and Physical Properties
Molecular Weight 762.9 g/mol
Molecular Formula C42H50N8O6
XLogP36.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count12
Exact Mass762.38533134 g/mol
Monoisotopic Mass762.38533134 g/mol
Topological Polar Surface Area175 Ų
Heavy Atom Count56
Formal Charge0
Complexity1400
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Ravidasvir Manufacturers

A Ravidasvir manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ravidasvir, including repackagers and relabelers. The FDA regulates Ravidasvir manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ravidasvir API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ravidasvir manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ravidasvir Suppliers

A Ravidasvir supplier is an individual or a company that provides Ravidasvir active pharmaceutical ingredient (API) or Ravidasvir finished formulations upon request. The Ravidasvir suppliers may include Ravidasvir API manufacturers, exporters, distributors and traders.

click here to find a list of Ravidasvir suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ravidasvir GMP

Ravidasvir Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ravidasvir GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ravidasvir GMP manufacturer or Ravidasvir GMP API supplier for your needs.

Ravidasvir CoA

A Ravidasvir CoA (Certificate of Analysis) is a formal document that attests to Ravidasvir's compliance with Ravidasvir specifications and serves as a tool for batch-level quality control.

Ravidasvir CoA mostly includes findings from lab analyses of a specific batch. For each Ravidasvir CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ravidasvir may be tested according to a variety of international standards, such as European Pharmacopoeia (Ravidasvir EP), Ravidasvir JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ravidasvir USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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