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Chemistry

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Also known as: Albendazole sulfoxide, Ricobendazole, 54029-12-8, Albendazole s-oxide, Rycobendazole, Albendazole-sulfoxide
Molecular Formula
C12H15N3O3S
Molecular Weight
281.33  g/mol
InChI Key
VXTGHWHFYNYFFV-UHFFFAOYSA-N
FDA UNII
J39B52TV34

Ricobendazole
albendazole oxide is a natural product found in Penicillium crustosum and Penicillium solitum with data available.
1 2D Structure

Ricobendazole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl N-(6-propylsulfinyl-1H-benzimidazol-2-yl)carbamate
2.1.2 InChI
InChI=1S/C12H15N3O3S/c1-3-6-19(17)8-4-5-9-10(7-8)14-11(13-9)15-12(16)18-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
2.1.3 InChI Key
VXTGHWHFYNYFFV-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCS(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC
2.2 Other Identifiers
2.2.1 UNII
J39B52TV34
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Albendazole Sulfoxide

2. Albendazole Sulfoxide, Monohydrochloride

3. Ricobendazole

2.3.2 Depositor-Supplied Synonyms

1. Albendazole Sulfoxide

2. Ricobendazole

3. 54029-12-8

4. Albendazole S-oxide

5. Rycobendazole

6. Albendazole-sulfoxide

7. (+-)-albendazole Sulfoxide

8. Rycoben

9. Rs 8852

10. Methyl N-(6-propylsulfinyl-1h-benzimidazol-2-yl)carbamate

11. Methyl 5-(propylsulfinyl)-2-benzimidazolecarbamate

12. (+/-)-albendazole Sulfoxide

13. Ricobendazole; Albendazole Oxide

14. Chebi:16959

15. J39b52tv34

16. Carbamic Acid, (5-propylsulfinyl)-1h-benzimidazol-2-yl)-, Methyl Ester

17. Rs-8852

18. Albendazole Oxide (inn)

19. Carbamic Acid, [5-(propylsulfinyl)-1h-benzimidazol-2-yl]-, Methyl Ester

20. 122063-20-1

21. Albendazole-sulfoxide 100 Microg/ml In Acetonitrile

22. Albendazole Oxide [inn]

23. Methyl [5-propylsulphinyl)-1h-benzimidazol-2-yl]carbamate

24. Methyl N-(5-propylsulfinyl-1h-benzimidazol-2-yl)carbamate

25. Methyl 5-(propylsulfinyl)-1h-benzo[d]imidazol-2-ylcarbamate

26. Albendazole Oxyde

27. Albendazolum Oxidum

28. Oxido De Albendazol

29. Albendazole Oxyde [inn-french]

30. Albendazolum Oxidum [inn-latin]

31. Oxido De Albendazol [inn-spanish]

32. Albendazole Oxide [inn:ban]

33. Unii-j39b52tv34

34. Methyl (5-propylsulfoxy)2-benzimidazolecarbamate

35. Mfcd00797922

36. Albendazole Sulphoxide

37. Chembl1665

38. Dsstox_cid_31557

39. Dsstox_rid_97442

40. Dsstox_gsid_57768

41. Mls006011133

42. Schembl321413

43. Dtxsid4057768

44. Albendazole Oxide (ricobendazole)

45. Ricobendazole, >=98% (hplc)

46. Albendazole Sulfoxide [mi]

47. Hms2090e05

48. Hms3655e16

49. Tox21_113873

50. Ac-016

51. Rs8852

52. S1836

53. Akos015905725

54. Akos015961126

55. As-7013

56. Ccg-267255

57. Db13871

58. Ncgc00253760-01

59. Ncgc00253760-02

60. Ncgc00386191-01

61. Hy-12785

62. Smr004702911

63. Cas-54029-12-8

64. Db-052462

65. Albendazole Impurity B [ep Impurity]

66. Cs-0012454

67. Ft-0621944

68. Sw219539-1

69. C02809

70. D07106

71. D81988

72. Ab01275491-01

73. Ab01275491_02

74. Albendazole-sulfoxide 100 Microg/ml In Methanol

75. 029a128

76. A829917

77. Sr-05000001502

78. J-519545

79. Sr-05000001502-1

80. Q27102154

81. Albendazole Sulfoxide, Vetranal(tm), Analytical Standard

82. Methoxy-n-[5-(propylsulfinyl)benzimidazol-2-yl]carboxamide

83. Methyl [5-(propylsulfinyl)-1h-benzimidazol-2-yl]carbamate

84. Methyl (6-(propylsulfinyl)-1h-benzo[d]imidazol-2-yl)carbamate

85. Methyl N-(5-(propylsulfinyl)-1h-benzimidazol-2-yl)carbamate

86. N-(6-propylsulfinyl-1h-benzimidazol-2-yl)carbamic Acid Methyl Ester

87. [5-(propylsulfinyl)-1h-benzimidazol-2-yl]carbamic Acid, Methyl Ester

88. Methyl (5-(propylsulfinyl)-1h-benzo(d)imidazol-2-yl)carbamate

89. Methyl N-[5-(propane-1-sulfinyl)-1h-1,3-benzodiazol-2-yl]carbamate

90. Methyl N-[6-(propane-1-sulfinyl)-1h-1,3-benzodiazol-2-yl]carbamate

91. Carbamic Acid, N-[5-(propylsulfinyl)-1h-benzimidazol-2-yl]-, Methyl Ester?

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 281.33 g/mol
Molecular Formula C12H15N3O3S
XLogP31.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass281.08341252 g/mol
Monoisotopic Mass281.08341252 g/mol
Topological Polar Surface Area103 Ų
Heavy Atom Count19
Formal Charge0
Complexity353
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anthelmintics

Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. (See all compounds classified as Anthelmintics.)


Anticestodal Agents

Agents used to treat tapeworm infestations in man or animals. (See all compounds classified as Anticestodal Agents.)


4.2 Metabolism/Metabolites

Albendazole oxide is a known human metabolite of albendazole.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


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09-Mar-2021
22-Nov-2024
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ABOUT THIS PAGE

Ricobendazole Manufacturers

A Ricobendazole manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ricobendazole, including repackagers and relabelers. The FDA regulates Ricobendazole manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ricobendazole API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ricobendazole manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ricobendazole Suppliers

A Ricobendazole supplier is an individual or a company that provides Ricobendazole active pharmaceutical ingredient (API) or Ricobendazole finished formulations upon request. The Ricobendazole suppliers may include Ricobendazole API manufacturers, exporters, distributors and traders.

click here to find a list of Ricobendazole suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ricobendazole GMP

Ricobendazole Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ricobendazole GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ricobendazole GMP manufacturer or Ricobendazole GMP API supplier for your needs.

Ricobendazole CoA

A Ricobendazole CoA (Certificate of Analysis) is a formal document that attests to Ricobendazole's compliance with Ricobendazole specifications and serves as a tool for batch-level quality control.

Ricobendazole CoA mostly includes findings from lab analyses of a specific batch. For each Ricobendazole CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ricobendazole may be tested according to a variety of international standards, such as European Pharmacopoeia (Ricobendazole EP), Ricobendazole JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ricobendazole USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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