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    Chemistry

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    Also known as:
    Molecular Formula
    C47H64N4O12
    Molecular Weight
    877.0  g/mol
    InChI Key
    RISDZDVHYCURHD-QLWTZYDESA-N
    Rifapentine
    1 2D Structure

    Rifapentine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z,26E)-26-[[(4-cyclopentylpiperazin-1-yl)amino]methylidene]-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29)-heptaen-13-yl] acetate
    2.1.2 InChI
    InChI=1S/C47H64N4O12/c1-24-13-12-14-25(2)46(59)49-37-32(23-48-51-20-18-50(19-21-51)31-15-10-11-16-31)41(56)34-35(42(37)57)40(55)29(6)44-36(34)45(58)47(8,63-44)61-22-17-33(60-9)26(3)43(62-30(7)52)28(5)39(54)27(4)38(24)53/h12-14,17,22-24,26-28,31,33,38-39,43,48,53-55,57H,10-11,15-16,18-21H2,1-9H3,(H,49,59)/b13-12+,22-17+,25-14-,32-23+/t24-,26+,27+,28+,33-,38-,39+,43+,47-/m0/s1
    2.1.3 InChI Key
    RISDZDVHYCURHD-QLWTZYDESA-N
    2.1.4 Canonical SMILES
    CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=O)C2=CNN5CCN(CC5)C6CCCC6)O)C
    2.1.5 Isomeric SMILES
    C[C@H]1/C=C/C=C(\C(=O)NC\2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C(=O)/C2=C/NN5CCN(CC5)C6CCCC6)O)/C
    2.2 Create Date
    2005-11-29
    3 Chemical and Physical Properties
    Molecular Weight 877.0 g/mol
    Molecular Formula C47H64N4O12
    XLogP35.8
    Hydrogen Bond Donor Count6
    Hydrogen Bond Acceptor Count15
    Rotatable Bond Count6
    Exact Mass876.45207349 g/mol
    Monoisotopic Mass876.45207349 g/mol
    Topological Polar Surface Area217 A^2
    Heavy Atom Count63
    Formal Charge0
    Complexity1870
    Isotope Atom Count0
    Defined Atom Stereocenter Count9
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count4
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NamePriftin
    PubMed HealthRifapentine (By mouth)
    Drug ClassesAntitubercular
    Drug LabelPRIFTIN (rifapentine) for oral administration contains 150 mg of the active ingredient rifapentine per tablet. The 150 mg tablets also contain, as inactive ingredients: calcium stearate, disodium EDTA, FD&C Blue No. 2 aluminum lake, hydroxypropyl cel.
    Active IngredientRifapentine
    Dosage FormTablet
    RouteOral
    Strength150mg
    Market StatusPrescription
    CompanySanofi Aventis Us

    2 of 2  
    Drug NamePriftin
    PubMed HealthRifapentine (By mouth)
    Drug ClassesAntitubercular
    Drug LabelPRIFTIN (rifapentine) for oral administration contains 150 mg of the active ingredient rifapentine per tablet. The 150 mg tablets also contain, as inactive ingredients: calcium stearate, disodium EDTA, FD&C Blue No. 2 aluminum lake, hydroxypropyl cel.
    Active IngredientRifapentine
    Dosage FormTablet
    RouteOral
    Strength150mg
    Market StatusPrescription
    CompanySanofi Aventis Us

    API Reference Price

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    [{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671993000,"product":"BULK DRUG : RIFAPENTINE","address":"KALPATARU INSPIRE, 3RD FLOOR, OFF WESTERN EXPRESS HIGHWAY SANTACRUZ E","city":"Mumbai","supplier":"LUPIN LTD","supplierCountry":"INDIA","foreign_port":"SHEREMETYEVO","customer":"PHARMCONCEPT LLC","customerCountry":"RUSSIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"2480","totalValueFC":"1917.3","currency":"USD","unitRateINR":158000,"date":"26-Dec-2022","totalValueINR":"158000","totalValueInUsd":"1917.3","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"6448750","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"KALPATARU INSPIRE, 3RD FLOOR, OFF WESTERN EXPRESS HIGHWAY SANTACRUZ E, Mumbai","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698172200,"product":"RIFAPENTINE (FORM-I) (TAX INVOICE NO:U123-24\/EXP\/086, DT:19.10.2023)","address":"48,49,50,209,210 211.PHASE-II","city":"","supplier":"ARENE LIFE SCIENCES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"TO THE ORDER OF","customerCountry":"INDONESIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"1250","totalValueFC":"1045.3","currency":"USD","unitRateINR":87000,"date":"25-Oct-2023","totalValueINR":"87000","totalValueInUsd":"1045.3","indian_port":"Hyderabad Air","hs_no":"29420090","bill_no":"4869146","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"48,49,50,209,210 211.PHASE-II, ","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715106600,"product":"RIFAPENTINE","address":"48,49,50,209,210 211.PHASE-II","city":"","supplier":"ARENE LIFE SCIENCES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"PT. KIMA FARMA TBK","customerCountry":"INDONESIA","quantity":"137.00","actualQuantity":"137","unit":"KGS","unitRateFc":"730","totalValueFC":"98238.3","currency":"USD","unitRateINR":59770.576642335764,"date":"08-May-2024","totalValueINR":"8188569","totalValueInUsd":"98238.3","indian_port":"Hyderabad Air","hs_no":"29420090","bill_no":"9720878","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"48,49,50,209,210 211.PHASE-II, ","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1632508200,"product":"RIFAPENTINE","address":"TUNG BALAMAJITHA ROAD","city":"AMRITSAR,PUNJAB","supplier":"M\/S. QUANZHOU FORTUEN TRADE CO.LTD","supplierCountry":"CHINA","foreign_port":"#N\/A","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"6.00","actualQuantity":"6","unit":"KGS","unitRateFc":"800","totalValueFC":"4855","currency":"USD","unitRateINR":"59520","date":"25-Sep-2021","totalValueINR":"357120","totalValueInUsd":"4855","indian_port":"DELHI AIR","hs_no":"29339990","bill_no":"5586443","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"TUNG BALAMAJITHA ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1643913000,"product":"(N.C.V.) RIFAPENTINE API BATCH: FF-VRE-000241-P42 (FOR R & DUNIT)","address":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO","city":"POWAI - MUMBAI CITY","supplier":"EUROAPI","supplierCountry":"GERMANY","foreign_port":"NA","customer":"SANOFI","customerCountry":"INDIA","quantity":"0.07","actualQuantity":"0.068","unit":"KGS","unitRateFc":"650","totalValueFC":"50.8","currency":"EUR","unitRateINR":"56030","date":"04-Feb-2022","totalValueINR":"3810.04","totalValueInUsd":"50.8","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"7355530","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1643913000,"product":"(N.C.V.) RIFAPENTINE API BATCH:LV21-172-TP5 (FOR R & D UNIT)","address":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO","city":"POWAI - MUMBAI CITY","supplier":"EUROAPI","supplierCountry":"GERMANY","foreign_port":"NA","customer":"SANOFI","customerCountry":"INDIA","quantity":"0.14","actualQuantity":"0.142","unit":"KGS","unitRateFc":"650","totalValueFC":"106.1","currency":"EUR","unitRateINR":"56030","date":"04-Feb-2022","totalValueINR":"7956.26","totalValueInUsd":"106.1","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"7355530","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655922600,"product":"(N.C.V) RIFAPENTINE API (FOR R & D UNIT)","address":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO","city":"POWAI - MUMBAI CITY","supplier":"EUROAPI","supplierCountry":"GERMANY","foreign_port":"NA","customer":"SANOFI","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"650","totalValueFC":"138.5","currency":"EUR","unitRateINR":"54015","date":"23-Jun-2022","totalValueINR":"10803","totalValueInUsd":"138.5","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"9242239","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1669401000,"product":"RIFAPENTINE","address":"NO 31, RACE COURSE ROAD BANGALORE Contact No: 919945641620","city":"BENGALURU","supplier":"EUROAPI","supplierCountry":"ITALY","foreign_port":"NA","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"12.30","actualQuantity":"12.3","unit":"KGS","unitRateFc":"800","totalValueFC":"10399.1","currency":"EUR","unitRateINR":"69000","date":"26-Nov-2022","totalValueINR":"848700","totalValueInUsd":"10399.1","indian_port":"MADRAS AIR","hs_no":"29419019","bill_no":"3476683","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NO 31, RACE COURSE ROAD BANGALORE Contact No: 919945641620"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1696617000,"product":"RIFAPENTINE","address":"NO.27,RACE COURSE ROAD,","city":"KARNATAKA","supplier":"EUROAPI","supplierCountry":"ITALY","foreign_port":"ROMA , QL","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"5.45","actualQuantity":"5.45","unit":"KGS","unitRateFc":"1190","totalValueFC":"6954.7","currency":"EUR","unitRateINR":"106207.5","date":"07-Oct-2023","totalValueINR":"578830.88","totalValueInUsd":"6954.7","indian_port":"Madras Air","hs_no":"29419019","bill_no":"8196805","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"ROMA , QL","supplierAddress":"VIA ANGELO TITI2272100 BRINDISI-BRSDNF ITALY","customerAddress":"NO.27,RACE COURSE ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718303400,"product":"RIFAPENTINE","address":"G\/6, INDL ESTATE, GORWA","city":"GUJARAT","supplier":"QINWEN (HEBEI) INTERNATIONAL TRADE","supplierCountry":"CHINA","foreign_port":"CHENGDU","customer":"CENTURION LABORATORIES","customerCountry":"INDIA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"550","totalValueFC":"83311","currency":"USD","unitRateINR":"46365","date":"14-Jun-2024","totalValueINR":"6954750","totalValueInUsd":"83311","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"3988494","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHENGDU","supplierAddress":"CO., LTD.ROOM 1308 WORLD TRADE PLAZA, NO.303ZHONGSHAN EAST ROAD, SHIJIAZHUANG,HEBEI, P.R. CHINA","customerAddress":"G\/6, INDL ESTATE, GORWA"}]
    25-Sep-2021
    14-Jun-2024
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    (KGS)    		 Average Price
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    ABOUT THIS PAGE

    Rifapentine Manufacturers

    A Rifapentine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Rifapentine, including repackagers and relabelers. The FDA regulates Rifapentine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Rifapentine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Rifapentine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Rifapentine Suppliers

    A Rifapentine supplier is an individual or a company that provides Rifapentine active pharmaceutical ingredient (API) or Rifapentine finished formulations upon request. The Rifapentine suppliers may include Rifapentine API manufacturers, exporters, distributors and traders.

    click here to find a list of Rifapentine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Rifapentine USDMF

    A Rifapentine DMF (Drug Master File) is a document detailing the whole manufacturing process of Rifapentine active pharmaceutical ingredient (API) in detail. Different forms of Rifapentine DMFs exist exist since differing nations have different regulations, such as Rifapentine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Rifapentine DMF submitted to regulatory agencies in the US is known as a USDMF. Rifapentine USDMF includes data on Rifapentine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Rifapentine USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Rifapentine suppliers with USDMF on PharmaCompass.

    Rifapentine WC

    A Rifapentine written confirmation (Rifapentine WC) is an official document issued by a regulatory agency to a Rifapentine manufacturer, verifying that the manufacturing facility of a Rifapentine active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Rifapentine APIs or Rifapentine finished pharmaceutical products to another nation, regulatory agencies frequently require a Rifapentine WC (written confirmation) as part of the regulatory process.

    click here to find a list of Rifapentine suppliers with Written Confirmation (WC) on PharmaCompass.

    Rifapentine NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Rifapentine as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Rifapentine API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Rifapentine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Rifapentine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Rifapentine NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Rifapentine suppliers with NDC on PharmaCompass.

    Rifapentine GMP

    Rifapentine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Rifapentine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Rifapentine GMP manufacturer or Rifapentine GMP API supplier for your needs.

    Rifapentine CoA

    A Rifapentine CoA (Certificate of Analysis) is a formal document that attests to Rifapentine's compliance with Rifapentine specifications and serves as a tool for batch-level quality control.

    Rifapentine CoA mostly includes findings from lab analyses of a specific batch. For each Rifapentine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Rifapentine may be tested according to a variety of international standards, such as European Pharmacopoeia (Rifapentine EP), Rifapentine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Rifapentine USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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