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    Chemistry

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    Also known as:
    Molecular Formula
    C47H64N4O12
    Molecular Weight
    877.0  g/mol
    InChI Key
    RISDZDVHYCURHD-QLWTZYDESA-N
    Rifapentine
    1 2D Structure

    Rifapentine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z,26E)-26-[[(4-cyclopentylpiperazin-1-yl)amino]methylidene]-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29)-heptaen-13-yl] acetate
    2.1.2 InChI
    InChI=1S/C47H64N4O12/c1-24-13-12-14-25(2)46(59)49-37-32(23-48-51-20-18-50(19-21-51)31-15-10-11-16-31)41(56)34-35(42(37)57)40(55)29(6)44-36(34)45(58)47(8,63-44)61-22-17-33(60-9)26(3)43(62-30(7)52)28(5)39(54)27(4)38(24)53/h12-14,17,22-24,26-28,31,33,38-39,43,48,53-55,57H,10-11,15-16,18-21H2,1-9H3,(H,49,59)/b13-12+,22-17+,25-14-,32-23+/t24-,26+,27+,28+,33-,38-,39+,43+,47-/m0/s1
    2.1.3 InChI Key
    RISDZDVHYCURHD-QLWTZYDESA-N
    2.1.4 Canonical SMILES
    CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=O)C2=CNN5CCN(CC5)C6CCCC6)O)C
    2.1.5 Isomeric SMILES
    C[C@H]1/C=C/C=C(\C(=O)NC\2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C(=O)/C2=C/NN5CCN(CC5)C6CCCC6)O)/C
    2.2 Create Date
    2005-11-29
    3 Chemical and Physical Properties
    Molecular Weight 877.0 g/mol
    Molecular Formula C47H64N4O12
    XLogP35.8
    Hydrogen Bond Donor Count6
    Hydrogen Bond Acceptor Count15
    Rotatable Bond Count6
    Exact Mass876.45207349 g/mol
    Monoisotopic Mass876.45207349 g/mol
    Topological Polar Surface Area217 A^2
    Heavy Atom Count63
    Formal Charge0
    Complexity1870
    Isotope Atom Count0
    Defined Atom Stereocenter Count9
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count4
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NamePriftin
    PubMed HealthRifapentine (By mouth)
    Drug ClassesAntitubercular
    Drug LabelPRIFTIN (rifapentine) for oral administration contains 150 mg of the active ingredient rifapentine per tablet. The 150 mg tablets also contain, as inactive ingredients: calcium stearate, disodium EDTA, FD&C Blue No. 2 aluminum lake, hydroxypropyl cel.
    Active IngredientRifapentine
    Dosage FormTablet
    RouteOral
    Strength150mg
    Market StatusPrescription
    CompanySanofi Aventis Us

    2 of 2  
    Drug NamePriftin
    PubMed HealthRifapentine (By mouth)
    Drug ClassesAntitubercular
    Drug LabelPRIFTIN (rifapentine) for oral administration contains 150 mg of the active ingredient rifapentine per tablet. The 150 mg tablets also contain, as inactive ingredients: calcium stearate, disodium EDTA, FD&C Blue No. 2 aluminum lake, hydroxypropyl cel.
    Active IngredientRifapentine
    Dosage FormTablet
    RouteOral
    Strength150mg
    Market StatusPrescription
    CompanySanofi Aventis Us

    API Reference Price

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    [{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671993000,"product":"BULK DRUG : RIFAPENTINE","address":"KALPATARU INSPIRE, 3RD FLOOR, OFF WESTERN EXPRESS HIGHWAY SANTACRUZ E","city":"Mumbai","supplier":"LUPIN LTD","supplierCountry":"INDIA","foreign_port":"SHEREMETYEVO","customer":"PHARMCONCEPT LLC","customerCountry":"RUSSIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"2480","totalValueFC":"1917.3","currency":"USD","unitRateINR":158000,"date":"26-Dec-2022","totalValueINR":"158000","totalValueInUsd":"1917.3","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"6448750","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"KALPATARU INSPIRE, 3RD FLOOR, OFF WESTERN EXPRESS HIGHWAY SANTACRUZ E, Mumbai","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713724200,"product":"BULK DRUG : RIFAPENTINE","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"LUPIN LTD","supplierCountry":"INDIA","foreign_port":"MEXICO CITY","customer":"HELM PORTUGAL","customerCountry":"MEXICO","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"1000","totalValueFC":"47567.9","currency":"USD","unitRateINR":79445.419999999998,"date":"22-Apr-2024","totalValueINR":"3972271","totalValueInUsd":"47567.9","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"9312905","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MEXICO","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"159, C.S.T. ROAD,, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715106600,"product":"RIFAPENTINE","address":"48,49,50,209,210 211.PHASE-II","city":"","supplier":"ARENE LIFE SCIENCES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"PT. KIMA FARMA TBK","customerCountry":"INDONESIA","quantity":"137.00","actualQuantity":"137","unit":"KGS","unitRateFc":"730","totalValueFC":"98238.3","currency":"USD","unitRateINR":59770.576642335764,"date":"08-May-2024","totalValueINR":"8188569","totalValueInUsd":"98238.3","indian_port":"Hyderabad Air","hs_no":"29420090","bill_no":"9720878","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"48,49,50,209,210 211.PHASE-II, ","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1643913000,"product":"(N.C.V.) RIFAPENTINE API BATCH: LV22-001-TP3 (FOR R & D UNIT)","address":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO","city":"POWAI - MUMBAI CITY","supplier":"EUROAPI","supplierCountry":"GERMANY","foreign_port":"NA","customer":"SANOFI","customerCountry":"INDIA","quantity":"0.29","actualQuantity":"0.288","unit":"KGS","unitRateFc":"650","totalValueFC":"215.3","currency":"EUR","unitRateINR":"56030","date":"04-Feb-2022","totalValueINR":"16136.64","totalValueInUsd":"215.3","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"7355530","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1643913000,"product":"(N.C.V.) RIFAPENTINE API BATCH: LV22-001-TP4 (FOR R & D UNIT)","address":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO","city":"POWAI - MUMBAI CITY","supplier":"EUROAPI","supplierCountry":"GERMANY","foreign_port":"NA","customer":"SANOFI","customerCountry":"INDIA","quantity":"0.21","actualQuantity":"0.21","unit":"KGS","unitRateFc":"650","totalValueFC":"157","currency":"EUR","unitRateINR":"56030","date":"04-Feb-2022","totalValueINR":"11766.3","totalValueInUsd":"157","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"7355530","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655922600,"product":"(N.C.V) RIFAPENTINE API (FOR R & D UNIT)","address":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO","city":"POWAI - MUMBAI CITY","supplier":"EUROAPI","supplierCountry":"GERMANY","foreign_port":"NA","customer":"SANOFI","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"650","totalValueFC":"138.5","currency":"EUR","unitRateINR":"54015","date":"23-Jun-2022","totalValueINR":"10803","totalValueInUsd":"138.5","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"9242239","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SANOFI HOUSE,C.T.S-117B, L AND T BUSINESS PARK,SAKI VIHAR RO"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1696617000,"product":"RIFAPENTINE","address":"NO.27,RACE COURSE ROAD,","city":"KARNATAKA","supplier":"EUROAPI","supplierCountry":"ITALY","foreign_port":"ROMA , QL","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"5.45","actualQuantity":"5.45","unit":"KGS","unitRateFc":"1190","totalValueFC":"6954.7","currency":"EUR","unitRateINR":"106207.5","date":"07-Oct-2023","totalValueINR":"578830.88","totalValueInUsd":"6954.7","indian_port":"Madras Air","hs_no":"29419019","bill_no":"8196805","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"ROMA , QL","supplierAddress":"VIA ANGELO TITI2272100 BRINDISI-BRSDNF ITALY","customerAddress":"NO.27,RACE COURSE ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714069800,"product":"RIFAPENTINE","address":"G\/6, INDL ESTATE, GORWA","city":"GUJARAT","supplier":"QINWEN (HEBEI) INTERNATIONAL TRADE","supplierCountry":"CHINA","foreign_port":"CHENGDU","customer":"CENTURION LABORATORIES","customerCountry":"INDIA","quantity":"541.40","actualQuantity":"541.4","unit":"KGS","unitRateFc":"550","totalValueFC":"300953.2","currency":"USD","unitRateINR":"46420","date":"26-Apr-2024","totalValueINR":"25131788","totalValueInUsd":"300953.2","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"3212557","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHENGDU","supplierAddress":"CO., LTD.ROOM 1308 WORLD TRADE PLAZA, NO.303ZHONGSHAN EAST ROAD, SHIJIAZHUANG,HEBEI, P.R. CHINA","customerAddress":"G\/6, INDL ESTATE, GORWA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718303400,"product":"RIFAPENTINE","address":"G\/6, INDL ESTATE, GORWA","city":"GUJARAT","supplier":"QINWEN (HEBEI) INTERNATIONAL TRADE","supplierCountry":"CHINA","foreign_port":"CHENGDU","customer":"CENTURION LABORATORIES","customerCountry":"INDIA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"550","totalValueFC":"83311","currency":"USD","unitRateINR":"46365","date":"14-Jun-2024","totalValueINR":"6954750","totalValueInUsd":"83311","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"3988494","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHENGDU","supplierAddress":"CO., LTD.ROOM 1308 WORLD TRADE PLAZA, NO.303ZHONGSHAN EAST ROAD, SHIJIAZHUANG,HEBEI, P.R. CHINA","customerAddress":"G\/6, INDL ESTATE, GORWA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720377000,"product":"RIFAPENTINE","address":"G\/6, INDL ESTATE, GORWA","city":"GUJARAT","supplier":"QINWEN (HEBEI) INTERNATIONAL TRADE","supplierCountry":"CHINA","foreign_port":"CHENGDU","customer":"CENTURION LABORATORIES","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"550","totalValueFC":"166695.4","currency":"USD","unitRateINR":"46447.5","date":"08-Jul-2024","totalValueINR":"13934250","totalValueInUsd":"166695.4","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"4385937","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHENGDU","supplierAddress":"CO., LTD.ROOM 1308 WORLD TRADE PLAZA, NO.303ZHONGSHAN EAST ROAD, SHIJIAZHUANG,HEBEI, P.R. CHINA","customerAddress":"G\/6, INDL ESTATE, GORWA"}]
    04-Feb-2022
    08-Jul-2024
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