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Chemistry

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Also known as: Mk-0657, 808732-98-1, Cerc-301, Rislenemdaz [usan], Rislenemdaz, (-)-, Mk-0657, (-)-
Molecular Formula
C19H23FN4O2
Molecular Weight
358.4  g/mol
InChI Key
RECBFDWSXWAXHY-IAGOWNOFSA-N
FDA UNII
1DY7M91WQ1

Rislenemdaz
Mk 0657 has been used in trials studying the treatment of Major Depressive Disorder.
1 2D Structure

Rislenemdaz

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4-methylphenyl)methyl (3S,4R)-3-fluoro-4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate
2.1.2 InChI
InChI=1S/C19H23FN4O2/c1-14-3-5-15(6-4-14)13-26-19(25)24-10-7-16(17(20)12-24)11-23-18-21-8-2-9-22-18/h2-6,8-9,16-17H,7,10-13H2,1H3,(H,21,22,23)/t16-,17-/m1/s1
2.1.3 InChI Key
RECBFDWSXWAXHY-IAGOWNOFSA-N
2.1.4 Canonical SMILES
CC1=CC=C(C=C1)COC(=O)N2CCC(C(C2)F)CNC3=NC=CC=N3
2.1.5 Isomeric SMILES
CC1=CC=C(C=C1)COC(=O)N2CC[C@@H]([C@@H](C2)F)CNC3=NC=CC=N3
2.2 Other Identifiers
2.2.1 UNII
1DY7M91WQ1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-methylbenzyl 3-fluoro-4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate

2. Mk-0657

2.3.2 Depositor-Supplied Synonyms

1. Mk-0657

2. 808732-98-1

3. Cerc-301

4. Rislenemdaz [usan]

5. Rislenemdaz, (-)-

6. Mk-0657, (-)-

7. 1dy7m91wq1

8. 5ham167s5t

9. 808733-05-3

10. Mk-0657, (+/-)-

11. 808732-98-1 (free Base)

12. 4-methylbenzyl (3s,4r)-3-fluoro-4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate

13. Rislenemdaz (usan)

14. Cis-4-methylbenzyl 3-fluoro-4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate

15. 1-piperidinecarboxylic Acid, 3-fluoro-4-((2-pyrimidinylamino)methyl)-, (4-methylphenyl)methyl Ester, (3r,4s)-rel-

16. 1-piperidinecarboxylic Acid, 3-fluoro-4-((2-pyrimidinylamino)methyl)-, (4-methylphenyl)methyl Ester, (3s,4r)-

17. Chembl2036513

18. 1-piperidinecarboxylic Acid, 3-fluoro-4-[(2-pyrimidinylamino)methyl]-, (4-methylphenyl)methyl Ester, (3r,4s)-rel-

19. Unii-1dy7m91wq1

20. Unii-5ham167s5t

21. Rislenemdaz [inn]

22. Rislenemdaz [who-dd]

23. Schembl4469674

24. Chembl2068839

25. Rislenemdaz, (+/-)-

26. Dtxsid801031864

27. Zinc6716889

28. Bdbm50385169

29. Mfcd14635204

30. Akos037643749

31. Cs-7798

32. Db12063

33. Hy-106441a

34. As-35130

35. D11340

36. Q18205913

37. Racemic Cis-4-methylbenzyl 3-fluoro-4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate

38. (-)-(3s,4r)-4-methylbenzyl 3-fluoro-4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate

39. (-)-(3s,4r)-4-methylbenzyl-3-flouro-4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate

40. (4-methylphenyl)methyl (3s,4r)-3-fluoro-4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate

41. 1221592-28-4

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 358.4 g/mol
Molecular Formula C19H23FN4O2
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass358.18050415 g/mol
Monoisotopic Mass358.18050415 g/mol
Topological Polar Surface Area67.4 Ų
Heavy Atom Count26
Formal Charge0
Complexity439
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1221592-28-4 / Rislenemdaz API manufacturers, exporters & distributors?

Rislenemdaz manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Rislenemdaz API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Rislenemdaz manufacturer or Rislenemdaz supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Rislenemdaz manufacturer or Rislenemdaz supplier.

PharmaCompass also assists you with knowing the Rislenemdaz API Price utilized in the formulation of products. Rislenemdaz API Price is not always fixed or binding as the Rislenemdaz Price is obtained through a variety of data sources. The Rislenemdaz Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Rislenemdaz

Synonyms

Mk-0657, 808732-98-1, Cerc-301, Rislenemdaz [usan], Rislenemdaz, (-)-, Mk-0657, (-)-

Cas Number

1221592-28-4

Unique Ingredient Identifier (UNII)

1DY7M91WQ1

About Rislenemdaz

Mk 0657 has been used in trials studying the treatment of Major Depressive Disorder.

Rislenemdaz Manufacturers

A Rislenemdaz manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Rislenemdaz, including repackagers and relabelers. The FDA regulates Rislenemdaz manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Rislenemdaz API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Rislenemdaz Suppliers

A Rislenemdaz supplier is an individual or a company that provides Rislenemdaz active pharmaceutical ingredient (API) or Rislenemdaz finished formulations upon request. The Rislenemdaz suppliers may include Rislenemdaz API manufacturers, exporters, distributors and traders.

Rislenemdaz GMP

Rislenemdaz Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Rislenemdaz GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Rislenemdaz GMP manufacturer or Rislenemdaz GMP API supplier for your needs.

Rislenemdaz CoA

A Rislenemdaz CoA (Certificate of Analysis) is a formal document that attests to Rislenemdaz's compliance with Rislenemdaz specifications and serves as a tool for batch-level quality control.

Rislenemdaz CoA mostly includes findings from lab analyses of a specific batch. For each Rislenemdaz CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Rislenemdaz may be tested according to a variety of international standards, such as European Pharmacopoeia (Rislenemdaz EP), Rislenemdaz JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Rislenemdaz USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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