Find Ritanserin manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

FDF

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 87051-43-2, Tiserton, Ritanserina, Ritanserine, Ritanserinum, R-55667
Molecular Formula
C27H25F2N3OS
Molecular Weight
477.6  g/mol
InChI Key
JUQLTPCYUFPYKE-UHFFFAOYSA-N
FDA UNII
145TFV465S

Ritanserin
A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
1 2D Structure

Ritanserin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one
2.1.2 InChI
InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3
2.1.3 InChI Key
JUQLTPCYUFPYKE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC3
2.2 Other Identifiers
2.2.1 UNII
145TFV465S
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6-(2-(4-(bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-5h-thiazolo(3,2-a)pyrimidin-5-one

2. R 55667

3. R-55667

4. R55667

5. Ritanserin Hydrochloride

6. Ritanserin Tartrate

2.3.2 Depositor-Supplied Synonyms

1. 87051-43-2

2. Tiserton

3. Ritanserina

4. Ritanserine

5. Ritanserinum

6. R-55667

7. R 55,667

8. 6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one

9. 6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one

10. Mfcd00069341

11. 6-(2-(4-(bis(p-fluorophenyl)methylene)-piperidino)ethyl)-7-methyl-5h-thiazolo-(3,2-a)pyrimidin-5-one

12. Nsc-758470

13. Mls000069360

14. Chembl267777

15. 6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one

16. 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5h-[1,3]thiazolo[3,2-a]pyrimidin-5-one

17. Chebi:64195

18. 145tfv465s

19. Ncgc00015877-06

20. Smr000058511

21. Dsstox_cid_22594

22. Dsstox_rid_80055

23. Dsstox_gsid_42594

24. 5h-thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-

25. 6-[2-[4-(bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one

26. 6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[2,3-b]pyrimidin-5-one

27. Ritanserine [french]

28. Ritanserinum [latin]

29. Ritanserina [spanish]

30. 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one

31. Cas-87051-43-2

32. Sr-01000000024

33. Ritanserin [usan:inn:ban]

34. Unii-145tfv465s

35. Ritanserin, Powder

36. Tiserton (tn)

37. 5h-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-

38. 6-[2-[4-[bis(p-fluorophenyl)methylene]-piperidino]ethyl]-7-methyl-5h-thiazolo-[3,2-a]pyrimidin-5-one

39. Spectrum_001830

40. Ritanserin [mi]

41. Lopac-r-103

42. Ritanserin [inn]

43. Opera_id_1609

44. Ritanserin (usan/inn)

45. Spectrum2_001560

46. Spectrum3_001023

47. Spectrum5_001504

48. Ritanserin [usan]

49. Ritanserin [vandf]

50. Gtpl97

51. Cid_5074

52. Ritanserin [mart.]

53. Ritanserin [who-dd]

54. Lopac0_001083

55. Regid_for_cid_5074

56. Schembl49227

57. Bspbio_002805

58. Kbioss_002335

59. Mls001148629

60. Divk1c_000192

61. Spbio_001440

62. Dtxsid9042594

63. Hms500j14

64. Kbio1_000192

65. Kbio2_002332

66. Kbio2_004900

67. Kbio2_007468

68. Kbio3_002025

69. Ninds_000192

70. Hms2093e19

71. Hms2233m22

72. Hms3263i08

73. Hms3268o04

74. Hms3373o19

75. Hms3412n14

76. Hms3676n14

77. Pharmakon1600-01503421

78. Zinc538314

79. Bcp13728

80. Tox21_110251

81. Tox21_501083

82. Bdbm50001775

83. Ccg-39338

84. Nsc758470

85. Nsc805597

86. Akos015909799

87. Tox21_110251_1

88. Db12693

89. Lp01083

90. Nsc 758470

91. Nsc-805597

92. Sdccgsbi-0051053.p004

93. 6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thia

94. Idi1_000192

95. Ncgc00015877-01

96. Ncgc00015877-02

97. Ncgc00015877-03

98. Ncgc00015877-04

99. Ncgc00015877-05

100. Ncgc00015877-07

101. Ncgc00015877-08

102. Ncgc00015877-09

103. Ncgc00015877-11

104. Ncgc00015877-15

105. Ncgc00022447-03

106. Ncgc00022447-04

107. Ncgc00022447-05

108. Ncgc00178460-01

109. Ncgc00261768-01

110. 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidyl]ethyl]-7-methyl-thiazolo[3,2-a]pyrimidin-5-one

111. Ac-30888

112. Bs-49232

113. Hy-10791

114. Sy274388

115. Sbi-0051053.p003

116. Db-056967

117. B6898

118. Cs-0002823

119. Eu-0101083

120. Ft-0630948

121. R-103

122. D05738

123. Ab00053288_14

124. 051r432

125. A848404

126. L001003

127. R 55667r 55667

128. Q3937260

129. Sr-01000000024-3

130. Sr-01000000024-4

131. Brd-k40887525-001-02-9

132. Brd-k40887525-001-14-4

133. Ethyl]-7-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one

134. 6-[2-[4-bis(4-fluorophenyl)methylene]-1-piperidinyl]-

135. (+)-6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one

136. (ritanserin)6-(2-{4-[bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1h-indolizin-5-one

137. (ritanserin)6-(2-{4-[bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one

138. 6-(2-(4-[bis(4-fluorophenyl)methylene]-1-piperidinyl)ethyl)-7-methyl-5h-[1,3]thiazolo[3,2-a]pyrimidin-5-one #

139. 6-(2-{4-[bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one

140. 6-(2-{4-[bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one

141. 6-(2-{4-[bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (ritanserin)

142. 6-(2-{4-[bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(ritanserin)

143. 6-[2-[4-[bis(4-fluorophenyl)-methylene]-1-piperidinyl]ethyl]-7-methyl-5h-thiazolo[3,2-a]-pyrimidin-5-one

144. E2j

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 477.6 g/mol
Molecular Formula C27H25F2N3OS
XLogP35.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass477.16863993 g/mol
Monoisotopic Mass477.16863993 g/mol
Topological Polar Surface Area61.2 Ų
Heavy Atom Count34
Formal Charge0
Complexity877
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antidepressive Agents, Second-Generation

A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. (See all compounds classified as Antidepressive Agents, Second-Generation.)


Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)


Serotonin Antagonists

Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. (See all compounds classified as Serotonin Antagonists.)


API SUPPLIERS

read-more
read-more
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Market Place

Do you need sourcing support? Ask us

ABOUT THIS PAGE

Ritanserin Manufacturers

A Ritanserin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ritanserin, including repackagers and relabelers. The FDA regulates Ritanserin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ritanserin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ritanserin Suppliers

A Ritanserin supplier is an individual or a company that provides Ritanserin active pharmaceutical ingredient (API) or Ritanserin finished formulations upon request. The Ritanserin suppliers may include Ritanserin API manufacturers, exporters, distributors and traders.

click here to find a list of Ritanserin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ritanserin USDMF

A Ritanserin DMF (Drug Master File) is a document detailing the whole manufacturing process of Ritanserin active pharmaceutical ingredient (API) in detail. Different forms of Ritanserin DMFs exist exist since differing nations have different regulations, such as Ritanserin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ritanserin DMF submitted to regulatory agencies in the US is known as a USDMF. Ritanserin USDMF includes data on Ritanserin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ritanserin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Ritanserin suppliers with USDMF on PharmaCompass.

Ritanserin GMP

Ritanserin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ritanserin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ritanserin GMP manufacturer or Ritanserin GMP API supplier for your needs.

Ritanserin CoA

A Ritanserin CoA (Certificate of Analysis) is a formal document that attests to Ritanserin's compliance with Ritanserin specifications and serves as a tool for batch-level quality control.

Ritanserin CoA mostly includes findings from lab analyses of a specific batch. For each Ritanserin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ritanserin may be tested according to a variety of international standards, such as European Pharmacopoeia (Ritanserin EP), Ritanserin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ritanserin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty