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Robenacoxib
Also known as: 220991-32-2, Onsior, Robenacoxib [inn], 2-(5-ethyl-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic acid, 2-[5-ethyl-2-(2,3,5,6-tetrafluoroanilino)phenyl]acetic acid, Chebi:76269
Molecular Formula
C16H13F4NO2
Molecular Weight
327.27  g/mol
InChI Key
ZEXGDYFACFXQPF-UHFFFAOYSA-N
FDA UNII
Z588009C7C

Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
1 2D Structure

Robenacoxib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[5-ethyl-2-(2,3,5,6-tetrafluoroanilino)phenyl]acetic acid
2.1.2 InChI
InChI=1S/C16H13F4NO2/c1-2-8-3-4-12(9(5-8)6-13(22)23)21-16-14(19)10(17)7-11(18)15(16)20/h3-5,7,21H,2,6H2,1H3,(H,22,23)
2.1.3 InChI Key
ZEXGDYFACFXQPF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCC1=CC(=C(C=C1)NC2=C(C(=CC(=C2F)F)F)F)CC(=O)O
2.2 Other Identifiers
2.2.1 UNII
Z588009C7C
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 220991-32-2

2. Onsior

3. Robenacoxib [inn]

4. 2-(5-ethyl-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic Acid

5. 2-[5-ethyl-2-(2,3,5,6-tetrafluoroanilino)phenyl]acetic Acid

6. Chebi:76269

7. Cgs 34975

8. Z588009c7c

9. (5-ethyl-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic Acid

10. Robenacoxibum

11. {5-ethyl-2-[(2,3,5,6-tetrafluorophenyl)amino]phenyl}acetic Acid

12. Robenacoxib [mi]

13. Schembl6036596

14. Zinc7562

15. Chembl2107774

16. Robenacoxib [green Book]

17. Unii-z588009c7c

18. Dtxsid90176607

19. Bcp23758

20. Mfcd27966869

21. Db11455

22. Ncgc00532515-01

23. Robenacoxib [ema Epar Veterinary]

24. Cs-0065148

25. Ft-0674451

26. C20708

27. A902615

28. J-014494

29. Q7341121

30. 5-ethyl-2-(2',3',5',6'-tetrafluoroanilino)phenylacetic Acid

31. 5-ethyl-2-(2', 3', 5', 6'-tetrafluoroanilino)phenylacetic Acid

32. 5-ethyl-2-(2', 3',5',6'-tetrafluoroanilino)phenylacetic Acid

33. 5-ethyl-2-(2',3',5', 6'-tetrafluoroanilino)phenylacetic Acid

34. 5-ethyl-2-(2',3',5',6'-tetrafluoroanilino) Phenylacetic Acid

2.4 Create Date
2006-04-28
3 Chemical and Physical Properties
Molecular Weight 327.27 g/mol
Molecular Formula C16H13F4NO2
XLogP34.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass327.08824131 g/mol
Monoisotopic Mass327.08824131 g/mol
Topological Polar Surface Area49.3 Ų
Heavy Atom Count23
Formal Charge0
Complexity398
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Cats (tablets):

For the treatmentRelief of pain and inflammation associated with acute andor chronic musculo-skeletal disorders.

For the reduction of moderate pain and inflammation associated with orthopaedic surgery.

Dogs (tablets):

For the Ttreatment of pain and inflammation associated with chronic osteoarthritis .

For the treatment of pain and inflammation associated with soft tissue surgery.

Cats and dogs (solution for injection):

For the Ttreatment of pain and inflammation associated with orthopaedic or soft tissue surgery.


5 Pharmacology and Biochemistry
5.1 ATC Code

QM01AH91


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