![EuroAPI Header](https://www.pharmacompass.com/image/flap/euroapi-w34-desktop-headergif-72716.gif)
![EuroAPI Header](https://www.pharmacompass.com/image/flap/euroapi-w34-mob-headergif-95876.gif)
API Suppliers
US DMFs Filed
CEP/COS Certifications
0
JDMFs Filed
0
EU WC
0
Listed Suppliers
0
USA (Orange Book)
Europe
0
Canada
0
Australia
0
South Africa
0
Uploaded Dossiers
0
U.S. Medicaid
Annual Reports
0
1. (5s,8s)-8-(((1r)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4.5)decan-2-one
2. 8-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4,5)decan-2-one
3. Rolapitant
4. Sch 619734
5. Varubi
1. Rolapitant Hydrochloride Hydrate
2. 914462-92-3
3. Rolapitant Hcl
4. Varubi
5. Sch619734
6. Rolapitant Hcl H20
7. Rolapitant Hydrochloride [usan]
8. Rolapitant Hydrochloride Monohydrate
9. 57o5s1qsaq
10. Varubi (tn)
11. (5s,8s)-8-(((1r)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4.5)decan-2-one Monohydrochloride Monohydrate
12. (5s,8s)-8-[[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one;hydrate;hydrochloride
13. Rolapitant Hydrochloride (usan)
14. Rolapitant Hcl Hydrate
15. 1,7-diazaspiro(4.5)decan-2-one, 8-(((1r)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-, Monohydrochloride, Monohydrate, (5s,8s)-
16. Unii-57o5s1qsaq
17. Rolapitant.hcl.h2o
18. Schembl2173125
19. Chembl3707330
20. Chebi:90911
21. Dtxsid70238570
22. Bcp15968
23. Mfcd19443696
24. Rolapitant Hydrochloride [mi]
25. Rolapitant Monohydrochloride Monohydrate
26. Ac-35397
27. Bs-17849
28. Rolapitant Hydrochloride [orange Book]
29. D08988
30. D83025
31. Rolapitant Hydrochloride Monohydrate [who-dd]
32. Q27162902
33. (5s,8s)-8-({(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-2-oxo-8-phenyl-1,7-diazaspiro[4.5]decan-7-ium Chloride--water (1/1)
34. (5s,8s)-8-({(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one Hydrochloride--water (1/1)
Molecular Weight | 555.0 g/mol |
---|---|
Molecular Formula | C25H29ClF6N2O3 |
Hydrogen Bond Donor Count | 4 |
Hydrogen Bond Acceptor Count | 10 |
Rotatable Bond Count | 5 |
Exact Mass | 554.1770895 g/mol |
Monoisotopic Mass | 554.1770895 g/mol |
Topological Polar Surface Area | 51.4 Ų |
Heavy Atom Count | 37 |
Formal Charge | 0 |
Complexity | 731 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 3 |
Neurokinin-1 Receptor Antagonists
Compounds that inhibit or block the activity of NEUROKININ-1 RECEPTORS. (See all compounds classified as Neurokinin-1 Receptor Antagonists.)