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Chemistry

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Also known as: Ronopterin, Ronopterin [inn], Vas203, 185243-78-1, Vas-203, 1d1z87ay23
Molecular Formula
C9H16N6O2
Molecular Weight
240.26  g/mol
InChI Key
NDSDGUULXHNXGA-RPDRRWSUSA-N
FDA UNII
1D1Z87AY23

Ronopterin
Ronopterin has been used in trials studying the treatment of Traumatic Brain Injury.
1 2D Structure

Ronopterin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,2S)-1-[(6R)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol
2.1.2 InChI
InChI=1S/C9H16N6O2/c1-3(16)6(17)4-2-12-8-5(13-4)7(10)14-9(11)15-8/h3-4,6,13,16-17H,2H2,1H3,(H5,10,11,12,14,15)/t3-,4+,6-/m0/s1
2.1.3 InChI Key
NDSDGUULXHNXGA-RPDRRWSUSA-N
2.1.4 Canonical SMILES
CC(C(C1CNC2=NC(=NC(=C2N1)N)N)O)O
2.1.5 Isomeric SMILES
C[C@@H]([C@@H]([C@H]1CNC2=NC(=NC(=C2N1)N)N)O)O
2.2 Other Identifiers
2.2.1 UNII
1D1Z87AY23
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2,4-diamino-5,6,7,8-tetrahydro-6(1,2-dihydroxypropyl)pteridine

2. 4-amino-h4biopterin

3. 4-amino-tetrahydrobiopterin

4. Ronopterin

5. Vas203

2.3.2 Depositor-Supplied Synonyms

1. Ronopterin

2. Ronopterin [inn]

3. Vas203

4. 185243-78-1

5. Vas-203

6. 1d1z87ay23

7. (1r,2s)-1-[(6r)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol

8. 1,2-propanediol, 1-(2,4-diamino-1,5,6,7-tetrahydro-6-pteridinyl)-, (1r,2s)-

9. 1,2-propanediol, 1-(2,4-diamino-5,6,7,8-tetrahydro-6-pteridinyl)-, (1r,2s)-

10. (1r,2s)-1-((r)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl)propane-1,2-diol

11. Unii-1d1z87ay23

12. (1r,2s)-1-((6r)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl)propane-1,2-diol

13. 4-amino-h4biopterin

14. 4-amino 5,6,7,8-tetrahydrobiopterin

15. Ronopterin [who-dd]

16. Ronopterin, (6r)-

17. Chembl1230245

18. Dtxsid9040394

19. Db12575

20. (1r,2s)-1-((6r)-2,4-diamino-5,6,7,8-tetrahydropteridin- 6-yl)propane-1,2-diol

21. 1,2-propanediol, 1-((6r)-2,4-diamino-5,6,7,8-tetrahydro-6-pteridinyl)-, (1r,2s)-

22. 2,4-diamino-6-[2,3-dihydroxy-prop-3-yl]-5,6,7,8-tetrahydropteridine

23. Q27252260

24. 2,4-diamino-5,6,7,8-tetrahydro-6(1,2-dihydroxypropyl)pteridine

25. (1r,2s)-1-(2,4-diamino-5,6,7,8-tetrahydro-6-pteridinyl)-1,2-propanediol

26. (6r)-2,4-diamino-5,6,7,8-tetrahydro-6-(-erythro-1,2-dihydroxypropyl)pteridine

27. (6r)-2,4-diamino-6beta-[(1r,2s)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridine

2.4 Create Date
2005-11-29
3 Chemical and Physical Properties
Molecular Weight 240.26 g/mol
Molecular Formula C9H16N6O2
XLogP3-1.2
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Exact Mass240.13347377 g/mol
Monoisotopic Mass240.13347377 g/mol
Topological Polar Surface Area142 Ų
Heavy Atom Count17
Formal Charge0
Complexity268
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 185243-78-1 / Ronopterin API manufacturers, exporters & distributors?

Ronopterin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ronopterin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ronopterin manufacturer or Ronopterin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ronopterin manufacturer or Ronopterin supplier.

PharmaCompass also assists you with knowing the Ronopterin API Price utilized in the formulation of products. Ronopterin API Price is not always fixed or binding as the Ronopterin Price is obtained through a variety of data sources. The Ronopterin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ronopterin

Synonyms

Ronopterin [inn], Vas203, 185243-78-1, Vas-203, 1d1z87ay23, (1r,2s)-1-[(6r)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol

Cas Number

185243-78-1

Unique Ingredient Identifier (UNII)

1D1Z87AY23

About Ronopterin

Ronopterin has been used in trials studying the treatment of Traumatic Brain Injury.

Ronopterin Manufacturers

A Ronopterin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ronopterin, including repackagers and relabelers. The FDA regulates Ronopterin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ronopterin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ronopterin Suppliers

A Ronopterin supplier is an individual or a company that provides Ronopterin active pharmaceutical ingredient (API) or Ronopterin finished formulations upon request. The Ronopterin suppliers may include Ronopterin API manufacturers, exporters, distributors and traders.

Ronopterin GMP

Ronopterin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ronopterin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ronopterin GMP manufacturer or Ronopterin GMP API supplier for your needs.

Ronopterin CoA

A Ronopterin CoA (Certificate of Analysis) is a formal document that attests to Ronopterin's compliance with Ronopterin specifications and serves as a tool for batch-level quality control.

Ronopterin CoA mostly includes findings from lab analyses of a specific batch. For each Ronopterin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ronopterin may be tested according to a variety of international standards, such as European Pharmacopoeia (Ronopterin EP), Ronopterin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ronopterin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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