Find RRx-001 manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Rrx-001, 925206-65-1, 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one, Abdnaz, Radiosensitizer rrx-001, 7rpw6su9sc
Molecular Formula
C5H6BrN3O5
Molecular Weight
268.02  g/mol
InChI Key
JODKFOVZURLVTG-UHFFFAOYSA-N
FDA UNII
7RPW6SU9SC

RRx-001
Radiosensitizer RRx-001 is a dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increasing tumor blood flow and thus improving oxygenation to the tumor site. By increasing oxygen levels, these tumor cells may be more susceptible to radiation therapy. Tumor hypoxia is correlated with tumor aggressiveness, metastasis and resistance to radiotherapy.
1 2D Structure

RRx-001

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone
2.1.2 InChI
InChI=1S/C5H6BrN3O5/c6-1-4(10)7-2-5(3-7,8(11)12)9(13)14/h1-3H2
2.1.3 InChI Key
JODKFOVZURLVTG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1C(CN1C(=O)CBr)([N+](=O)[O-])[N+](=O)[O-]
2.2 Other Identifiers
2.2.1 UNII
7RPW6SU9SC
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 14c-rrx-001

2. Rrx-001

2.3.2 Depositor-Supplied Synonyms

1. Rrx-001

2. 925206-65-1

3. 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

4. Abdnaz

5. Radiosensitizer Rrx-001

6. 7rpw6su9sc

7. Ethanone, 2-bromo-1-(3,3-dinitro-1-azetidinyl)-

8. Unii-7rpw6su9sc

9. Rrx 001

10. Rrx001

11. Schembl2249018

12. Chembl3526802

13. Rrx 001 [who-dd]

14. 1-bromoacetyl-3,3-dinitroazetidine

15. Bcp19228

16. Ex-a2006

17. Mfcd25976849

18. S8405

19. Zinc34805177

20. N-(bromoacetyl)-3,3-dinitroazetidine

21. Akos037644389

22. Ccg-267126

23. Cs-5286

24. Db12060

25. Ac-32908

26. As-53015

27. Br164811

28. Hy-16438

29. P15978

30. Q27268765

2.4 Create Date
2007-03-07
3 Chemical and Physical Properties
Molecular Weight 268.02 g/mol
Molecular Formula C5H6BrN3O5
XLogP30
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass266.94908 g/mol
Monoisotopic Mass266.94908 g/mol
Topological Polar Surface Area112 Ų
Heavy Atom Count14
Formal Charge0
Complexity273
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 925206-65-1 / RRx-001 API manufacturers, exporters & distributors?

RRx-001 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of RRx-001 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right RRx-001 manufacturer or RRx-001 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred RRx-001 manufacturer or RRx-001 supplier.

PharmaCompass also assists you with knowing the RRx-001 API Price utilized in the formulation of products. RRx-001 API Price is not always fixed or binding as the RRx-001 Price is obtained through a variety of data sources. The RRx-001 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

RRx-001

Synonyms

925206-65-1, 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one, Abdnaz, Radiosensitizer rrx-001, 7rpw6su9sc, Ethanone, 2-bromo-1-(3,3-dinitro-1-azetidinyl)-

Cas Number

925206-65-1

Unique Ingredient Identifier (UNII)

7RPW6SU9SC

About RRx-001

Radiosensitizer RRx-001 is a dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increasing tumor blood flow and thus improving oxygenation to the tumor site. By increasing oxygen levels, these tumor cells may be more susceptible to radiation therapy. Tumor hypoxia is correlated with tumor aggressiveness, metastasis and resistance to radiotherapy.

Rrx 001 Manufacturers

A Rrx 001 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Rrx 001, including repackagers and relabelers. The FDA regulates Rrx 001 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Rrx 001 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Rrx 001 Suppliers

A Rrx 001 supplier is an individual or a company that provides Rrx 001 active pharmaceutical ingredient (API) or Rrx 001 finished formulations upon request. The Rrx 001 suppliers may include Rrx 001 API manufacturers, exporters, distributors and traders.

Rrx 001 GMP

Rrx 001 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Rrx 001 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Rrx 001 GMP manufacturer or Rrx 001 GMP API supplier for your needs.

Rrx 001 CoA

A Rrx 001 CoA (Certificate of Analysis) is a formal document that attests to Rrx 001's compliance with Rrx 001 specifications and serves as a tool for batch-level quality control.

Rrx 001 CoA mostly includes findings from lab analyses of a specific batch. For each Rrx 001 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Rrx 001 may be tested according to a variety of international standards, such as European Pharmacopoeia (Rrx 001 EP), Rrx 001 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Rrx 001 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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