Find Rubidazone Monohydrochloride manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Rubidazone, Rubidazone monohydrochloride, Rp 22,050 hydrochloride, Nsc-164011, N-[(e)-1-[(2s,4s)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1h-tetracen-2-yl]ethylideneamino]benzamide;hydrochloride, Nsc164011
Molecular Formula
C34H36ClN3O10
Molecular Weight
682.1  g/mol
InChI Key
NKFHKYQGZDAKMX-CBGHEUOKSA-N

Rubidazone Monohydrochloride
Zorubicin Hydrochloride is a benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04)
1 2D Structure

Rubidazone Monohydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[(E)-1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]benzamide;hydrochloride
2.1.2 InChI
InChI=1S/C34H35N3O10.ClH/c1-15-28(38)20(35)12-23(46-15)47-22-14-34(44,16(2)36-37-33(43)17-8-5-4-6-9-17)13-19-25(22)32(42)27-26(30(19)40)29(39)18-10-7-11-21(45-3)24(18)31(27)41;/h4-11,15,20,22-23,28,38,40,42,44H,12-14,35H2,1-3H3,(H,37,43);1H/b36-16+;/t15?,20?,22-,23?,28?,34-;/m0./s1
2.1.3 InChI Key
NKFHKYQGZDAKMX-CBGHEUOKSA-N
2.1.4 Canonical SMILES
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=NNC(=O)C6=CC=CC=C6)C)O)N)O.Cl
2.1.5 Isomeric SMILES
CC1C(C(CC(O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(/C(=N/NC(=O)C6=CC=CC=C6)/C)O)N)O.Cl
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Daunomycin Benzoylhydrazone

2. Rp 22050

3. Rubidazone

4. Zorubicin

5. Zorubicin Hydrochloride, (l-xylo)-(2s-cis)-isomer

6. Zorubicin, (l-arabino)-(2s-cis)-isomer

7. Zorubicine

2.2.2 Depositor-Supplied Synonyms

1. Rubidazone

2. Rubidazone Monohydrochloride

3. Rp 22,050 Hydrochloride

4. Nsc-164011

5. N-[(e)-1-[(2s,4s)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1h-tetracen-2-yl]ethylideneamino]benzamide;hydrochloride

6. Nsc164011

7. 36508-71-1

8. Rubidaz

9. Zorubicinhydrochlorid

10. Daunorubicin, Monohydrochloride

11. Chembl1975668

12. Rp 22050

13. Benzoic Acid Hydrazide, Monohydrochlorideone

14. 22050 R.p.

15. Benzoic Acid [1-[4-[(3-amino-2,6-trideoxy-.alpha.-l-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide, (2s-cis)-, Monohydrochloride

16. Benzoic Acid,3,6-trideoxy-.alpha.-l-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide, Monohydrochloride, (2s-cis)-

2.3 Create Date
2006-10-24
3 Chemical and Physical Properties
Molecular Weight 682.1 g/mol
Molecular Formula C34H36ClN3O10
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count12
Rotatable Bond Count6
Exact Mass681.2089220 g/mol
Monoisotopic Mass681.2089220 g/mol
Topological Polar Surface Area210 Ų
Heavy Atom Count48
Formal Charge0
Complexity1230
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count4
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antibiotics, Antineoplastic

Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. (See all compounds classified as Antibiotics, Antineoplastic.)


ABOUT THIS PAGE

Rubidazone Monohydrochloride Manufacturers

A Rubidazone Monohydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Rubidazone Monohydrochloride, including repackagers and relabelers. The FDA regulates Rubidazone Monohydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Rubidazone Monohydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Rubidazone Monohydrochloride Suppliers

A Rubidazone Monohydrochloride supplier is an individual or a company that provides Rubidazone Monohydrochloride active pharmaceutical ingredient (API) or Rubidazone Monohydrochloride finished formulations upon request. The Rubidazone Monohydrochloride suppliers may include Rubidazone Monohydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Rubidazone Monohydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Rubidazone Monohydrochloride USDMF

A Rubidazone Monohydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Rubidazone Monohydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Rubidazone Monohydrochloride DMFs exist exist since differing nations have different regulations, such as Rubidazone Monohydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Rubidazone Monohydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Rubidazone Monohydrochloride USDMF includes data on Rubidazone Monohydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Rubidazone Monohydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Rubidazone Monohydrochloride suppliers with USDMF on PharmaCompass.

Rubidazone Monohydrochloride GMP

Rubidazone Monohydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Rubidazone Monohydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Rubidazone Monohydrochloride GMP manufacturer or Rubidazone Monohydrochloride GMP API supplier for your needs.

Rubidazone Monohydrochloride CoA

A Rubidazone Monohydrochloride CoA (Certificate of Analysis) is a formal document that attests to Rubidazone Monohydrochloride's compliance with Rubidazone Monohydrochloride specifications and serves as a tool for batch-level quality control.

Rubidazone Monohydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Rubidazone Monohydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Rubidazone Monohydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Rubidazone Monohydrochloride EP), Rubidazone Monohydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Rubidazone Monohydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty