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Chemistry

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Also known as: 101363-10-4, Mf 934, Nsc-759835, Chebi:8909, Rufloxacin (inn), Y521xm2900
Molecular Formula
C17H18FN3O3S
Molecular Weight
363.4  g/mol
InChI Key
NJCJBUHJQLFDSW-UHFFFAOYSA-N
FDA UNII
Y521XM2900

Rufloxacin Hydrochloride
Rufloxacin is a quinolone antibiotic.
1 2D Structure

Rufloxacin Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-fluoro-6-(4-methylpiperazin-1-yl)-10-oxo-4-thia-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
2.1.2 InChI
InChI=1S/C17H18FN3O3S/c1-19-2-4-20(5-3-19)14-12(18)8-10-13-16(14)25-7-6-21(13)9-11(15(10)22)17(23)24/h8-9H,2-7H2,1H3,(H,23,24)
2.1.3 InChI Key
NJCJBUHJQLFDSW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F
2.2 Other Identifiers
2.2.1 UNII
Y521XM2900
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 9-fluoro-10-(n-(4'-methyl)piperazinyl)-7-oxo-2,3-dihydro-7h-pyrido(1,2,3de)-1,4-benzothiazine-6-carboxylic Acid

2. Mf 934

3. Mf-934

4. Rufloxacin Hydrobromide

5. Rufloxacin Hydrochloride

6. Rufloxacin Monohydrobromide

7. Rufloxacin Monohydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 101363-10-4

2. Mf 934

3. Nsc-759835

4. Chebi:8909

5. Rufloxacin (inn)

6. Y521xm2900

7. 7h-pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic Acid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-

8. Rufloxacine

9. Rufloxacino

10. Rufloxacinum

11. Rufloxacin [inn]

12. 9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7h-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic Acid

13. 9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7h-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic Acid;9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7h-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic Acid

14. Smr000466373

15. Rufloxacine [french]

16. Rufloxacinum [latin]

17. Rufloxacino [spanish]

18. Rufloxacin [inn:ban]

19. Sr-01000612324

20. Ncgc00074024-02

21. Unii-y521xm2900

22. Rufloxacin [mi]

23. Rufloxacin [who-dd]

24. Mls000759502

25. Mls001424127

26. Schembl135502

27. Chembl295619

28. Dtxsid6048412

29. Hms2051k22

30. Hms2090n07

31. Hms3264m18

32. Hms3393k22

33. Hms3715p09

34. Pharmakon1600-01502335

35. Zinc538328

36. Hy-b0902

37. Rkl10066

38. Bbl008945

39. Nsc759835

40. Stk711124

41. Akos004120047

42. Ccg-100908

43. Cs-4367

44. Db13772

45. Nc00158

46. Nsc 759835

47. As-79943

48. Ft-0631011

49. D02474

50. Ab00474020-18

51. Ab00474020-20

52. Ab00474020_21

53. 363r104

54. Q3942356

55. Sr-01000612324-5

56. Sr-01000612324-6

57. 7-fluoro-6-(4-methylpiperazin-1-yl)-10-oxo-4-thia-1-azatricyclo[7.3.1.0^{5,13]trideca-5(13),6,8,11-tetraene-11-carboxylic Acid

58. 7-fluoro-6-(4-methylpiperazin-1-yl)-10-oxo-4-thia-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic Acid

59. 8-fluoro-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6h-1-thia-3a-aza-phenalene-5-carboxylic Acid

60. 8-fluoro-9-(4-methylpiperazin-1-yl)-6-oxo-2,3-dihydro-6h-1-thia-3a-aza-phenalene-5-carboxylic Acid

61. 9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2h-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic Acid

62. 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido(1,2,3-de)-1,4-benzothiazine-6-carboxylic Acid

63. 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic Acid

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 363.4 g/mol
Molecular Formula C17H18FN3O3S
XLogP3-0.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Exact Mass363.10529078 g/mol
Monoisotopic Mass363.10529078 g/mol
Topological Polar Surface Area89.4 Ų
Heavy Atom Count25
Formal Charge0
Complexity608
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Topoisomerase II Inhibitors

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)


4.2 ATC Code

J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01M - Quinolone antibacterials

J01MA - Fluoroquinolones

J01MA10 - Rufloxacin


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ABOUT THIS PAGE

Rufloxacin Hydrochloride Manufacturers

A Rufloxacin Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Rufloxacin Hydrochloride, including repackagers and relabelers. The FDA regulates Rufloxacin Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Rufloxacin Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Rufloxacin Hydrochloride Suppliers

A Rufloxacin Hydrochloride supplier is an individual or a company that provides Rufloxacin Hydrochloride active pharmaceutical ingredient (API) or Rufloxacin Hydrochloride finished formulations upon request. The Rufloxacin Hydrochloride suppliers may include Rufloxacin Hydrochloride API manufacturers, exporters, distributors and traders.

Rufloxacin Hydrochloride GMP

Rufloxacin Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Rufloxacin Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Rufloxacin Hydrochloride GMP manufacturer or Rufloxacin Hydrochloride GMP API supplier for your needs.

Rufloxacin Hydrochloride CoA

A Rufloxacin Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Rufloxacin Hydrochloride's compliance with Rufloxacin Hydrochloride specifications and serves as a tool for batch-level quality control.

Rufloxacin Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Rufloxacin Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Rufloxacin Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Rufloxacin Hydrochloride EP), Rufloxacin Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Rufloxacin Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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