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Synopsis

ACTIVE PHARMA INGREDIENTS

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JDMF

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KDMF

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NDC API

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NDC API

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4 RELATED EXCIPIENT COMPANIES

7EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 153-18-4, Rutoside, Quercetin 3-rutinoside, Birutan, Phytomelin, Myrticolorin
Molecular Formula
C27H30O16
Molecular Weight
610.5  g/mol
InChI Key
IKGXIBQEEMLURG-NVPNHPEKSA-N
FDA UNII
5G06TVY3R7

Rutin
A flavonol glycoside found in many plants, including BUCKWHEAT; TOBACCO; FORSYTHIA; HYDRANGEA; VIOLA, etc. It has been used therapeutically to decrease capillary fragility.
1 2D Structure

Rutin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
2.1.2 InChI
InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1
2.1.3 InChI Key
IKGXIBQEEMLURG-NVPNHPEKSA-N
2.1.4 Canonical SMILES
CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
2.1.5 Isomeric SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
5G06TVY3R7
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3-rhamnosyl-glucosyl Quercetin

2. Quercetin 3 Rutinoside

3. Quercetin, 3-rhamnosyl-glucosyl

4. Quercetin-3-rutinoside

5. Rutoside

2.3.2 Depositor-Supplied Synonyms

1. 153-18-4

2. Rutoside

3. Quercetin 3-rutinoside

4. Birutan

5. Phytomelin

6. Myrticolorin

7. Eldrin

8. Globulariacitrin

9. Rutin Trihydrate

10. Ilixanthin

11. Osyritrin

12. Paliuroside

13. Tanrutin

14. Sophorin

15. Bioflavonoid

16. Globularicitrin

17. Rutabion

18. Venoruton

19. 3-rutinosyl Quercetin

20. Violaquercitrin

21. Yunxianggan

22. 3-rhamnoglucosylquercetin

23. Rutine

24. Rutozyd

25. Melin

26. Quercetin 3-o-rutinoside

27. Rutinic Acid

28. Birutan Forte

29. Quercetin-3-rutinoside

30. Oxyritin

31. Rutinum

32. Rutosido

33. Rutosidum

34. Rutinion Acid

35. Vitamin P

36. Quercitin 3-rutinoside

37. Novarrutina

38. Violaquercetrin

39. Birutin

40. Quercetin Rhamnoglucosine

41. Quercetin-3-o-rutinoside

42. Quercetin-3beta-rutinoside

43. Quercetin 3-rhamnoglucoside

44. Quercetol 3-rhamnoglucoside

45. C.i. 75730

46. Rutosid

47. Rutoside [inn]

48. 3,3',4',5,7-pentahydroxyflavone-3-rutinoside

49. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-((((2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)methyl)tetrahydro-2h-pyran-2-yl)oxy)-4h-chromen-4-one

50. Quercetin 3-o-beta-d-rutinoside

51. 5g06tvy3r7

52. Chembl226335

53. Chebi:28527

54. Rutoside (inn)

55. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranoside

56. 3-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4h-1-benzopyran-4-one

57. 3-rhamnoglucoside Of 3,3',4',5,7-pentahydroxyflavone

58. Ncgc00160628-01

59. Nsc-9220

60. Dsstox_cid_2326

61. Dsstox_rid_76549

62. Dsstox_gsid_22326

63. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one

64. 4h-1-benzopyran-4-one,3-[[6-o-(6-deoxy-a-l-mannopyranosyl)-b-d-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

65. Rut

66. Rutoside (rutin)

67. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chromen-4-one

68. 3-((6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4h-1-benzopyran-4-one

69. Cas-153-18-4

70. Smr000112560

71. Rutin [jan:nf]

72. Rutosidum [inn-latin]

73. Rutosido [inn-spanish]

74. Usaf Cf-5

75. Unii-5g06tvy3r7

76. Neoisorutin

77. Ccris 7564

78. Rutinoside, Quercetin-3, Beta-

79. Hydroxyethylrutoside

80. Rutin (rutoside)

81. Venoruton (tn)

82. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-mannopyranoside

83. Nsc 9220

84. Einecs 205-814-1

85. Mfcd00006830

86. Rutin,(s)

87. Brn 0075455

88. 3,3',4',5,7-pentahydroxyflavone 3-rutinoside

89. Ai3-19098

90. Rutin [vandf]

91. Rutin [inci]

92. 207671-50-9

93. Rutin [dsc]

94. Rutin [usp-rs]

95. Rutin [mi]

96. Rutoside [inn:jan:nf]

97. Rutoside [who-dd]

98. Beta-quercetin-3-rutinoside

99. Bidd:pxr0020

100. Schembl23243

101. 4h-1-benzopyran-4-one, 3-((6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

102. 5-18-05-00519 (beilstein Handbook Reference)

103. Mls000759398

104. Mls001424098

105. Bidd:er0377

106. Divk1c_000644

107. Megxp0_000068

108. Rutin From Sophora Japonica L.

109. Dtxsid3022326

110. Acon1_000075

111. Cid_5280805

112. Hms502a06

113. Kbio1_000644

114. Rutin (95%)

115. Ninds_000644

116. 3,3',4',5,7-pentahydroxyflavone-3-rhamnoglucoside

117. Hms2051b06

118. 3'4'5,7-tetoh-flavone-3-rut

119. Flavone, 3,3',4',5,7-pentahydroxy-, 3-(o-rhamnosylglucoside)

120. Hy-n0148

121. Zinc4096846

122. Quercetin 3-o-beta-delta-rutinoside

123. Tox21_111945

124. Tox21_202602

125. Bdbm50217942

126. Glucopyranoside, Quercetin-3 6-o-alpha-l-rhamnopyranosyl-, Beta-d

127. Quercetin, 3-(6-o-alpha-l-rhamnopyranosyl-beta-d-glucopyranoside)

128. S2350

129. 3,3',4',5,5',7-hexahydroxyflavone (6-o-alpha-l-rhamnosyl-beta-d-glucoside)

130. Akos015895432

131. Glucopyranoside, Quercetin-3 6-o-(6-deoxy-alpha-l-mannopyranosyl)-, Beta-d-

132. Quercetin, 3-(6-0-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranoside)

133. Tox21_111945_1

134. Ccg-100999

135. Cs-5573

136. Db01698

137. Ds-9708

138. Nc00249

139. Idi1_000644

140. Rutinoside, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-1-benzopyran-3-yl

141. Ncgc00160628-02

142. Ncgc00160628-03

143. Ncgc00260150-01

144. 4h-1-benzopyran-4-one, 3-[[6-o-(6-deoxy-.alpha.-l-mannopyranosyl)-.beta.-d-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

145. Methyltetrahydro-2h-pyran-2-yloxy)methyl)

146. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3

147. R0035

148. C05625

149. D08499

150. Ab00374708-09

151. Tetrahydro-2h-pyran-2-yloxy)-4h-chromen-4-one

152. A809400

153. Q407857

154. Sr-01000759399

155. Q-201691

156. Sr-01000759399-5

157. A8241da0-6ec6-48ba-bd10-3f7bd61d42ce

158. Brd-k20482099-001-01-1

159. Brd-k20482099-001-11-0

160. 3,3,4,5,7-pentahydroxyflavone-3-rhamnoglucoside

161. 3-rhamnoglucoside Of 5,7,3',4'-tetrahydroxyflavonol

162. Quercetin 3-o-[alpha-l-rhamnosyl-(1->6)-beta-d-glucoside]

163. Quercetin 3-o-.alpha.-l-rhamnopyranosyl-.beta.-d-glucopyranoside

164. Rutin (quercetin-3-o-rutinoside) (constituent Of Ginkgo) [dsc]

165. Rutin (quercetin-3-o-rutinoside) (constituent Of Hawthorn Leaf With Flower) [dsc]

166. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-((((2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)methyl)tetrahydro-2h-pyran-2-yl)oxy)-4h-chromen-4-one;rutin

167. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(((2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yloxy)methyl)tetrahydro-2h-pyran-2-yloxy)-4h-chromen-4-one

168. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4h-chromen-4-one

169. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4h-chromen-4-one-3-yl 6-o-.alpha.-l-rhamnopyranosyl-.beta.-d-glucoside

170. 4h-1-benzopyran-4-one, 3-[[6-o-(6-deoxy-.alpha.-l-mannopyranosyl)-.beta.-d-glucopyranosyl]-oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 610.5 g/mol
Molecular Formula C27H30O16
XLogP3-1.3
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count16
Rotatable Bond Count6
Exact Mass610.15338487 g/mol
Monoisotopic Mass610.15338487 g/mol
Topological Polar Surface Area266 Ų
Heavy Atom Count43
Formal Charge0
Complexity1020
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

C05CA01

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


C - Cardiovascular system

C05 - Vasoprotectives

C05C - Capillary stabilizing agents

C05CA - Bioflavonoids

C05CA01 - Rutoside


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RAYMOND ARON,92160 ANTONY FRANCESDNF France","customerAddress":"3RD 4TH FLOORS, H.NO. 5-10-173"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722882600,"product":"IBRUTINIB API","address":"F 2, NO.18-17, CITY HOME RESIDENCY,","city":"HYDERABAD, AP.","supplier":"GYMA LABORATORIES OF AMERICA, INC.","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"SP ACCURE LABS PVT. 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REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"2.60","actualQuantity":"2.6","unit":"KGS","unitRateFc":"15500","totalValueFC":"41193.7","currency":"USD","unitRateINR":"1337024.2","date":"19-Nov-2024","totalValueINR":"3476262.89","totalValueInUsd":"41193.7","indian_port":"Hyderabad Air","hs_no":"29420090","bill_no":"6750475","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ZHOUPU INTERNATIONAL MEDICAL ZONE NO.588, TIANXIONG RD SHANGHAI 20012 0 CHINA CN","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"}]
12-Mar-2021
19-Nov-2024
KGS
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Rutin Manufacturers

A Rutin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Rutin, including repackagers and relabelers. The FDA regulates Rutin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Rutin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Rutin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Rutin Suppliers

A Rutin supplier is an individual or a company that provides Rutin active pharmaceutical ingredient (API) or Rutin finished formulations upon request. The Rutin suppliers may include Rutin API manufacturers, exporters, distributors and traders.

click here to find a list of Rutin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Rutin USDMF

A Rutin DMF (Drug Master File) is a document detailing the whole manufacturing process of Rutin active pharmaceutical ingredient (API) in detail. Different forms of Rutin DMFs exist exist since differing nations have different regulations, such as Rutin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Rutin DMF submitted to regulatory agencies in the US is known as a USDMF. Rutin USDMF includes data on Rutin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Rutin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Rutin suppliers with USDMF on PharmaCompass.

Rutin CEP

A Rutin CEP of the European Pharmacopoeia monograph is often referred to as a Rutin Certificate of Suitability (COS). The purpose of a Rutin CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Rutin EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Rutin to their clients by showing that a Rutin CEP has been issued for it. The manufacturer submits a Rutin CEP (COS) as part of the market authorization procedure, and it takes on the role of a Rutin CEP holder for the record. Additionally, the data presented in the Rutin CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Rutin DMF.

A Rutin CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Rutin CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Rutin suppliers with CEP (COS) on PharmaCompass.

Rutin WC

A Rutin written confirmation (Rutin WC) is an official document issued by a regulatory agency to a Rutin manufacturer, verifying that the manufacturing facility of a Rutin active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Rutin APIs or Rutin finished pharmaceutical products to another nation, regulatory agencies frequently require a Rutin WC (written confirmation) as part of the regulatory process.

click here to find a list of Rutin suppliers with Written Confirmation (WC) on PharmaCompass.

Rutin GMP

Rutin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Rutin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Rutin GMP manufacturer or Rutin GMP API supplier for your needs.

Rutin CoA

A Rutin CoA (Certificate of Analysis) is a formal document that attests to Rutin's compliance with Rutin specifications and serves as a tool for batch-level quality control.

Rutin CoA mostly includes findings from lab analyses of a specific batch. For each Rutin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Rutin may be tested according to a variety of international standards, such as European Pharmacopoeia (Rutin EP), Rutin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Rutin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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