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Chemistry

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Also known as: Rzl-012, Chembl5314928, Schembl14965985, 9h-carbazole-9-pentanaminium, 3,6-dibromo-n,n,n-trimethyl-, chloride (1:1), 1436920-57-8
Molecular Formula
C20H25Br2ClN2
Molecular Weight
488.7  g/mol
InChI Key
GYDHQSBIPOHCIM-UHFFFAOYSA-M
FDA UNII
M8BBT7ORRM

RZL-012
Utenpanium Chloride is a synthetic small molecule thermogenic regulator, that may potentially be used for the treatment of Dercum's Disease lipomas. Although the exact mechanisms(s) through which this agent exerts its effects have yet to be fully elucidated, upon subcutaneous injection into lipomas, utenpanium chloride activates thermogenesis in subcutaneous fat, turning fat into heat. This may lead to fat cell death and the shrinkage of fat tissue.
1 2D Structure

RZL-012

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-(3,6-dibromocarbazol-9-yl)pentyl-trimethylazanium;chloride
2.1.2 InChI
InChI=1S/C20H25Br2N2.ClH/c1-24(2,3)12-6-4-5-11-23-19-9-7-15(21)13-17(19)18-14-16(22)8-10-20(18)23;/h7-10,13-14H,4-6,11-12H2,1-3H3;1H/q+1;/p-1
2.1.3 InChI Key
GYDHQSBIPOHCIM-UHFFFAOYSA-M
2.2 Other Identifiers
2.2.1 UNII
M8BBT7ORRM
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5-(3,6-dibromo-9h-carbazol-9-yl)-n,n,n-trimethylpentan-1-aminium Chloride

2. Rzl-012

2.3.2 Depositor-Supplied Synonyms

1. Rzl-012

2. Chembl5314928

3. Schembl14965985

4. 9h-carbazole-9-pentanaminium, 3,6-dibromo-n,n,n-trimethyl-, Chloride (1:1)

5. 1436920-57-8

2.4 Create Date
2013-06-11
3 Chemical and Physical Properties
Molecular Weight 488.7 g/mol
Molecular Formula C20H25Br2ClN2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count6
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area4.9
Heavy Atom Count25
Formal Charge0
Complexity383
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

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